JP2017513636A5 - - Google Patents

Info

Publication number

JP2017513636A5

JP2017513636A5 JP2016564198A JP2016564198A JP2017513636A5 JP 2017513636 A5 JP2017513636 A5 JP 2017513636A5 JP 2016564198 A JP2016564198 A JP 2016564198A JP 2016564198 A JP2016564198 A JP 2016564198A JP 2017513636 A5 JP2017513636 A5 JP 2017513636A5

Authority

JP

Japan

Prior art keywords

sample

bacteria

heparin

bacterium

beads

Prior art date

2015-04-17

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

• Espacenet
• Global Dossier
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• 238000000034 method Methods 0.000 claims 21
• 241000894006 Bacteria Species 0.000 claims 13
• HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 6
• 239000011324 bead Substances 0.000 claims 6
• 229960002897 heparin Drugs 0.000 claims 6
• 229920000669 heparin Polymers 0.000 claims 5
• 229920002971 Heparan sulfate Polymers 0.000 claims 4
• 239000003463 adsorbent Substances 0.000 claims 4
• 150000004676 glycans Chemical class 0.000 claims 4
• 229920001282 polysaccharide Polymers 0.000 claims 4
• 239000005017 polysaccharide Substances 0.000 claims 4
• 239000000758 substrate Substances 0.000 claims 4
• 239000007787 solid Substances 0.000 claims 3
• 238000001179 sorption measurement Methods 0.000 claims 3
• 241000588724 Escherichia coli Species 0.000 claims 2
• 241000588747 Klebsiella pneumoniae Species 0.000 claims 2
• 239000000853 adhesive Substances 0.000 claims 2
• 230000001070 adhesive effect Effects 0.000 claims 2
• 239000008280 blood Substances 0.000 claims 2
• 210000004369 blood Anatomy 0.000 claims 2
• YZBQHRLRFGPBSL-RXMQYKEDSA-N carbapenem Chemical compound C1C=CN2C(=O)C[C@H]21 YZBQHRLRFGPBSL-RXMQYKEDSA-N 0.000 claims 2
• -1 polyethylene Polymers 0.000 claims 2
• 229920000642 polymer Polymers 0.000 claims 2
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
• 241000588626 Acinetobacter baumannii Species 0.000 claims 1
• 229920001661 Chitosan Polymers 0.000 claims 1
• 108090000204 Dipeptidase 1 Proteins 0.000 claims 1
• 241000194031 Enterococcus faecium Species 0.000 claims 1
• VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 1
• 239000005977 Ethylene Substances 0.000 claims 1
• 239000004698 Polyethylene Substances 0.000 claims 1
• 229920002873 Polyethylenimine Polymers 0.000 claims 1
• 229920002367 Polyisobutene Polymers 0.000 claims 1
• 239000004743 Polypropylene Substances 0.000 claims 1
• 230000002745 absorbent Effects 0.000 claims 1
• 239000002250 absorbent Substances 0.000 claims 1
• SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 claims 1
• 102000006635 beta-lactamase Human genes 0.000 claims 1
• 150000001720 carbohydrates Chemical class 0.000 claims 1
• 235000014633 carbohydrates Nutrition 0.000 claims 1
• 229920001577 copolymer Polymers 0.000 claims 1
• 239000012510 hollow fiber Substances 0.000 claims 1
• 229920002674 hyaluronan Polymers 0.000 claims 1
• 229960003160 hyaluronic acid Drugs 0.000 claims 1
• 238000000338 in vitro Methods 0.000 claims 1
• 125000000311 mannosyl group Chemical group C1([C@@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
• 239000000178 monomer Substances 0.000 claims 1
• 210000002381 plasma Anatomy 0.000 claims 1
• 229920003229 poly(methyl methacrylate) Polymers 0.000 claims 1
• 229920000573 polyethylene Polymers 0.000 claims 1
• 239000004926 polymethyl methacrylate Substances 0.000 claims 1
• 229920001155 polypropylene Polymers 0.000 claims 1
• 229920002635 polyurethane Polymers 0.000 claims 1
• 239000004814 polyurethane Substances 0.000 claims 1
• 238000000159 protein binding assay Methods 0.000 claims 1
• 210000002966 serum Anatomy 0.000 claims 1
• SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 claims 1