JP2017510580A5 - - Google Patents
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- JP2017510580A5 JP2017510580A5 JP2016558569A JP2016558569A JP2017510580A5 JP 2017510580 A5 JP2017510580 A5 JP 2017510580A5 JP 2016558569 A JP2016558569 A JP 2016558569A JP 2016558569 A JP2016558569 A JP 2016558569A JP 2017510580 A5 JP2017510580 A5 JP 2017510580A5
- Authority
- JP
- Japan
- Prior art keywords
- genus
- oxo
- amino
- morganella
- citrobacter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 201000009906 Meningitis Diseases 0.000 claims description 6
- 241000588771 Morganella <proteobacterium> Species 0.000 claims description 6
- 241000589291 Acinetobacter Species 0.000 claims description 5
- 241001453380 Burkholderia Species 0.000 claims description 5
- 241000588923 Citrobacter Species 0.000 claims description 5
- 241000588914 Enterobacter Species 0.000 claims description 5
- 241000588722 Escherichia Species 0.000 claims description 5
- 241000588748 Klebsiella Species 0.000 claims description 5
- 241000588653 Neisseria Species 0.000 claims description 5
- 241000588769 Proteus <enterobacteria> Species 0.000 claims description 5
- 241000589516 Pseudomonas Species 0.000 claims description 5
- 241000607142 Salmonella Species 0.000 claims description 5
- 241000607720 Serratia Species 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- 241000606125 Bacteroides Species 0.000 claims description 3
- 241000589876 Campylobacter Species 0.000 claims description 3
- 241000122971 Stenotrophomonas Species 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims description 3
- 241000894007 species Species 0.000 claims description 3
- 208000035143 Bacterial infection Diseases 0.000 claims description 2
- 230000001580 bacterial effect Effects 0.000 claims description 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 4
- YMGUBTXCNDTFJI-UHFFFAOYSA-N cyclopropanecarboxylic acid Chemical compound OC(=O)C1CC1 YMGUBTXCNDTFJI-UHFFFAOYSA-N 0.000 claims 2
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- -1 2-aminothiazol-4-yl Chemical group 0.000 claims 1
- 241000255925 Diptera Species 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000000034 method Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000027096 gram-negative bacterial infections Diseases 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461969735P | 2014-03-24 | 2014-03-24 | |
| US61/969,735 | 2014-03-24 | ||
| US201462088304P | 2014-12-05 | 2014-12-05 | |
| US62/088,304 | 2014-12-05 | ||
| PCT/US2015/022011 WO2015148379A1 (en) | 2014-03-24 | 2015-03-23 | Monobactam organic compounds for the treatment of bacterial infections |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017510580A JP2017510580A (ja) | 2017-04-13 |
| JP2017510580A5 true JP2017510580A5 (cg-RX-API-DMAC7.html) | 2017-06-01 |
| JP6153674B2 JP6153674B2 (ja) | 2017-06-28 |
Family
ID=52808201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016558569A Active JP6153674B2 (ja) | 2014-03-24 | 2015-03-23 | 細菌感染を治療するためのモノバクタム有機化合物 |
Country Status (37)
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108137573B (zh) * | 2015-09-23 | 2021-06-11 | 诺华股份有限公司 | 单环内酰胺抗生素的盐和固体形式 |
| US20180282331A1 (en) | 2015-11-09 | 2018-10-04 | Wockhardt Limited | 7-Oxo -6-(sulfooxy)- 1,6-diazabicyclo [3.2.1] octane containing compounds and their use in treatment of bacterial infections (changed by PCT to: 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS |
| JP7184646B2 (ja) * | 2015-12-15 | 2022-12-06 | メルク・シャープ・アンド・ドーム・エルエルシー | ビアリールモノバクタム化合物および細菌感染治療のためのそれの使用方法 |
| MX2018010878A (es) | 2016-03-07 | 2018-11-09 | Merck Sharp & Dohme | Compuestos de aril-monobactam biciclicos y metodos de uso de los mismos para el tratamiento de infecciones bacterianas. |
| IL269390B (en) | 2017-03-20 | 2022-08-01 | Broad Inst Inc | Compounds and methods for the treatment of parasitic diseases |
| CA3063649A1 (en) | 2017-08-02 | 2019-02-07 | Novartis Ag | Chemical process for manufacturing monobactam antibiotic and intermediates thereof |
| WO2019058346A1 (en) * | 2017-09-22 | 2019-03-28 | Novartis Ag | MONOBACTAM ADMINISTRATION IN ASSOCIATION WITH ANTIBIOTIC AGENT FOR THE TREATMENT OF COMPLICATED INTRA-ABDOMINAL INFECTION |
| KR102455390B1 (ko) * | 2017-10-02 | 2022-10-17 | 아릭사 파마슈티컬스 인코포레이티드 | 아즈트레오남 유도체 및 이의 용도 |
| MX2020003581A (es) | 2017-10-02 | 2020-07-22 | Merck Sharp & Dohme | Compuestos monobactamicos cromanos para el tratamiento de infecciones bacterianas. |
| WO2019092180A1 (en) * | 2017-11-10 | 2019-05-16 | Novartis Ag | Administration of monobactam for the treatment of urinary tract infection |
| JP7280273B2 (ja) | 2018-01-29 | 2023-05-23 | メッドシャイン ディスカバリー インコーポレイテッド | 細菌感染を治療するための単環β－ラクタム化合物 |
| KR102017784B1 (ko) * | 2018-04-11 | 2019-09-03 | 전북대학교산학협력단 | 민감성 및 선택성을 개선한 캠필로박터 검출용 배지 조성물 및 이를 이용한 캠필로박터 검출방법 |
| KR102017785B1 (ko) * | 2018-05-17 | 2019-09-03 | 전북대학교산학협력단 | 민감성 및 선택성을 개선한 캠필로박터 선택증균용 배지 조성물 및 이를 이용한 캠필로박터 검출방법 |
| US11905286B2 (en) | 2018-08-09 | 2024-02-20 | Antabio Sas | Diazabicyclooctanones as inhibitors of serine beta-lactamases |
| FI3833665T3 (fi) | 2018-08-09 | 2023-10-09 | Antabio Sas | Diatsabisyklo-oktanoneja seriini-beeta-laktamaasien inhibiittoreina |
| US20220002288A1 (en) | 2018-11-13 | 2022-01-06 | Nanjing Sanhome Pharmaceutical Co., Ltd. | Monobactam compounds and use therefor |
| US12310948B2 (en) | 2018-12-18 | 2025-05-27 | Shenzhen Optimum Biological Technology Co., Ltd | Application of monocyclic β-lactam compound in pharmacy |
| CN114787158B (zh) * | 2019-11-22 | 2023-10-24 | 苏州二叶制药有限公司 | 磺酰脲环取代的单环β-内酰胺类抗生素 |
| CN111303144B (zh) * | 2019-12-13 | 2020-11-27 | 苏州信诺维医药科技有限公司 | 一种治疗细菌感染的化合物 |
| WO2021121387A1 (zh) | 2019-12-19 | 2021-06-24 | 南京明德新药研发有限公司 | 化合物在制药中的应用 |
| EP3838266A1 (en) | 2019-12-20 | 2021-06-23 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Microfluidic production of biofunctionalized giant unilamellar vesicles for targeted intracellular cargo delivery |
| CN113754651B (zh) * | 2020-06-02 | 2023-04-18 | 中国医学科学院医药生物技术研究所 | 一种β-内酰胺化合物、其用途及其制备方法 |
| CN115210231B (zh) * | 2020-07-16 | 2024-10-08 | 宁夏农林科学院 | 单环内酰胺类化合物、其制备方法及其作为抗菌药的用途 |
| WO2022185240A1 (en) | 2021-03-04 | 2022-09-09 | Bp Asset Vi, Inc. | Formulation of a monobactam antibiotic |
| WO2022185241A1 (en) | 2021-03-04 | 2022-09-09 | Bp Asset Vi, Inc. | Process for manufacturing a monobactam antibiotic |
| KR20240105442A (ko) * | 2021-11-18 | 2024-07-05 | 머크 샤프 앤드 돔 엘엘씨 | 크로만 아미딘 모노박탐 항생제 |
| CN115304594B (zh) | 2022-10-12 | 2023-02-14 | 苏州二叶制药有限公司 | 磺酰脲环取代的化合物的盐型及其晶型 |
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2015
- 2015-03-23 UA UAA201608977A patent/UA121383C2/uk unknown
- 2015-03-23 LT LTEP15714147.4T patent/LT3122745T/lt unknown
- 2015-03-23 JP JP2016558569A patent/JP6153674B2/ja active Active
- 2015-03-23 AU AU2015236369A patent/AU2015236369B2/en active Active
- 2015-03-23 MY MYPI2016702871A patent/MY179292A/en unknown
- 2015-03-23 EA EA201691766A patent/EA030850B1/ru not_active IP Right Cessation
- 2015-03-23 HU HUE15714147A patent/HUE042134T2/hu unknown
- 2015-03-23 CN CN201580015867.7A patent/CN106164072B/zh active Active
- 2015-03-23 DK DK18215940.0T patent/DK3511328T3/da active
- 2015-03-23 BR BR112016020333-0A patent/BR112016020333B1/pt active IP Right Grant
- 2015-03-23 CU CU2016000131A patent/CU24441B1/es unknown
- 2015-03-23 KR KR1020167024716A patent/KR101733441B1/ko active Active
- 2015-03-23 RS RS20190406A patent/RS58509B1/sr unknown
- 2015-03-23 WO PCT/US2015/022011 patent/WO2015148379A1/en not_active Ceased
- 2015-03-23 PL PL15714147T patent/PL3122745T3/pl unknown
- 2015-03-23 AP AP2016009374A patent/AP2016009374A0/en unknown
- 2015-03-23 SG SG11201606711UA patent/SG11201606711UA/en unknown
- 2015-03-23 EP EP18215940.0A patent/EP3511328B1/en active Active
- 2015-03-23 PT PT15714147T patent/PT3122745T/pt unknown
- 2015-03-23 MX MX2016011822A patent/MX373444B/es active IP Right Grant
- 2015-03-23 DK DK15714147.4T patent/DK3122745T3/en active
- 2015-03-23 HR HRP20190501TT patent/HRP20190501T1/hr unknown
- 2015-03-23 SM SM20190218T patent/SMT201900218T1/it unknown
- 2015-03-23 CA CA2939254A patent/CA2939254C/en active Active
- 2015-03-23 SI SI201530680T patent/SI3122745T1/sl unknown
- 2015-03-23 ES ES18215940T patent/ES2862203T3/es active Active
- 2015-03-23 MA MA39777A patent/MA39777B1/fr unknown
- 2015-03-23 TW TW104109243A patent/TWI714525B/zh active
- 2015-03-23 PE PE2016001601A patent/PE20161371A1/es unknown
- 2015-03-23 PH PH1/2016/501577A patent/PH12016501577B1/en unknown
- 2015-03-23 US US14/665,245 patent/US9174978B2/en active Active
- 2015-03-23 EP EP15714147.4A patent/EP3122745B1/en active Active
- 2015-03-23 ES ES15714147T patent/ES2719136T3/es active Active
- 2015-09-22 US US14/861,797 patent/US10369138B2/en active Active
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2016
- 2016-08-11 ZA ZA2016/05565A patent/ZA201605565B/en unknown
- 2016-08-14 IL IL247259A patent/IL247259B/en active IP Right Grant
- 2016-09-09 CL CL2016002285A patent/CL2016002285A1/es unknown
- 2016-09-12 SV SV2016005274A patent/SV2016005274A/es unknown
- 2016-09-12 EC ECIEPI201673620A patent/ECSP16073620A/es unknown
- 2016-09-12 GT GT201600183A patent/GT201600183A/es unknown
-
2019
- 2019-04-03 CY CY20191100371T patent/CY1121701T1/el unknown
- 2019-04-10 US US16/380,243 patent/US20190231752A1/en not_active Abandoned
-
2020
- 2020-03-19 US US16/823,485 patent/US20200276169A1/en not_active Abandoned
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