JP2017500013A5 - - Google Patents
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- Publication number
- JP2017500013A5 JP2017500013A5 JP2016527450A JP2016527450A JP2017500013A5 JP 2017500013 A5 JP2017500013 A5 JP 2017500013A5 JP 2016527450 A JP2016527450 A JP 2016527450A JP 2016527450 A JP2016527450 A JP 2016527450A JP 2017500013 A5 JP2017500013 A5 JP 2017500013A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- chelating agent
- cell population
- stem cells
- culture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 16
- 210000004027 cell Anatomy 0.000 claims 14
- 239000002738 chelating agent Substances 0.000 claims 7
- 102000004190 Enzymes Human genes 0.000 claims 5
- 108090000790 Enzymes Proteins 0.000 claims 5
- 210000001778 pluripotent stem cell Anatomy 0.000 claims 5
- 210000000130 stem cell Anatomy 0.000 claims 3
- 238000004114 suspension culture Methods 0.000 claims 3
- 108090000145 Bacillolysin Proteins 0.000 claims 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 2
- 102000035092 Neutral proteases Human genes 0.000 claims 2
- 108091005507 Neutral proteases Proteins 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 1
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 claims 1
- 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 claims 1
- 108010076089 accutase Proteins 0.000 claims 1
- 238000004115 adherent culture Methods 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 210000004381 amniotic fluid Anatomy 0.000 claims 1
- 229940098773 bovine serum albumin Drugs 0.000 claims 1
- 239000006285 cell suspension Substances 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 238000006911 enzymatic reaction Methods 0.000 claims 1
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000002107 myocardial effect Effects 0.000 claims 1
- 210000005155 neural progenitor cell Anatomy 0.000 claims 1
- 230000008186 parthenogenesis Effects 0.000 claims 1
- 239000003590 rho kinase inhibitor Substances 0.000 claims 1
- 210000003954 umbilical cord Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361962158P | 2013-11-01 | 2013-11-01 | |
| US61/962,158 | 2013-11-01 | ||
| US13/998,974 US10377989B2 (en) | 2012-12-31 | 2013-12-30 | Methods for suspension cultures of human pluripotent stem cells |
| US13/998,974 | 2013-12-30 | ||
| PCT/US2014/042796 WO2015065537A1 (en) | 2013-11-01 | 2014-06-17 | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017500013A JP2017500013A (ja) | 2017-01-05 |
| JP2017500013A5 true JP2017500013A5 (enExample) | 2018-03-29 |
Family
ID=53004904
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016527338A Pending JP2016534731A (ja) | 2013-11-01 | 2014-05-21 | 膵内分泌細胞への分化のためのヒト多能性幹細胞の懸濁及び集団化 |
| JP2016527450A Pending JP2017500013A (ja) | 2013-11-01 | 2014-06-17 | 膵内分泌細胞への分化のためのヒト多能性幹細胞の懸濁及び集団化 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016527338A Pending JP2016534731A (ja) | 2013-11-01 | 2014-05-21 | 膵内分泌細胞への分化のためのヒト多能性幹細胞の懸濁及び集団化 |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP3063268A4 (enExample) |
| JP (2) | JP2016534731A (enExample) |
| KR (4) | KR20160079072A (enExample) |
| CN (2) | CN105793413A (enExample) |
| AU (4) | AU2014342995C1 (enExample) |
| BR (1) | BR112016009393A8 (enExample) |
| CA (2) | CA2928639A1 (enExample) |
| MX (2) | MX2016005657A (enExample) |
| PH (2) | PH12016500782A1 (enExample) |
| RU (2) | RU2689710C2 (enExample) |
| SG (2) | SG11201603045VA (enExample) |
| WO (2) | WO2015065524A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2689710C2 (ru) * | 2013-11-01 | 2019-05-29 | Янссен Байотек, Инк. | Суспендирование и кластеризация плюрипотентных стволовых клеток человека с целью их дифференцировки в панкреатические эндокринные клетки |
| RU2771328C2 (ru) * | 2016-06-23 | 2022-04-29 | Титон Биотек, Инк. | Клетки, экспрессирующие рецептор паратиреоидного гормона 1, и их применение |
| CN118924958A (zh) | 2016-11-10 | 2024-11-12 | 韦尔赛特公司 | 含有pdx1胰腺内胚层细胞的细胞递送装置及其方法 |
| AU2017361117B9 (en) | 2016-11-16 | 2022-03-24 | Cynata Therapeutics Limited | Pluripotent stem cell assay |
| US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
| EP4488363A3 (en) * | 2017-07-21 | 2025-03-26 | Vertex Pharmaceuticals Incorporated | Re-aggregation of stem cell-derived pancreatic beta cells |
| JP7000896B2 (ja) * | 2017-08-23 | 2022-01-19 | 王子ホールディングス株式会社 | 細胞シート形成部材、細胞シート形成部材の製造方法、および、細胞シートの製造方法 |
| AU2019205942B2 (en) * | 2018-01-05 | 2025-05-15 | Platelet Biogenesis, Inc. | Compositions and methods for producing megakaryocytes |
| JP2021510527A (ja) * | 2018-01-18 | 2021-04-30 | エージェンシー フォー サイエンス， テクノロジー アンド リサーチ | 懸濁培養におけるヒト多能性幹細胞系の分化のための方法 |
| KR102115360B1 (ko) * | 2018-05-30 | 2020-05-26 | 주식회사 바이블리오테카 | 성체 줄기세포 배양액 및 그 제조방법 |
| US12378572B2 (en) | 2018-09-07 | 2025-08-05 | Crispr Therapeutics Ag | Universal donor cells |
| CA3139292C (en) | 2019-05-31 | 2025-06-10 | Viacyte, Inc. | CELL ENCAPSULATION DEVICES WITH REGULATED OXYGEN DIFFUSION DISTANCES |
| WO2020243666A1 (en) | 2019-05-31 | 2020-12-03 | W. L. Gore & Associates, Inc. | A biocompatible membrane composite |
| AU2020282355B2 (en) | 2019-05-31 | 2023-11-02 | Viacyte, Inc. | A biocompatible membrane composite |
| AU2020283056B2 (en) | 2019-05-31 | 2023-06-08 | Viacyte, Inc. | A biocompatible membrane composite |
| KR20220090496A (ko) * | 2019-08-27 | 2022-06-29 | 유나이티드 쎄러퓨틱스 코포레이션 | 폐포 세포를 배양하기 위한 방법 및 조성물 |
| US11118196B2 (en) | 2019-09-05 | 2021-09-14 | Crispr Therapeutics Ag | Universal donor cells |
| KR20220058579A (ko) | 2019-09-05 | 2022-05-09 | 크리스퍼 테라퓨틱스 아게 | 보편적 공여자 세포 |
| WO2021099532A1 (en) * | 2019-11-22 | 2021-05-27 | Novo Nordisk A/S | Spin-aggregated neural microspheres and the application thereof |
| WO2022144856A1 (en) | 2020-12-31 | 2022-07-07 | Crispr Therapeutics Ag | Universal donor cells |
| US20240191185A1 (en) * | 2021-03-25 | 2024-06-13 | Kaneka Corporation | Method for producing pluripotent stem cell population |
| JP2022151855A (ja) * | 2021-03-25 | 2022-10-07 | 株式会社カネカ | 多能性幹細胞集団の製造方法 |
| CN116218766A (zh) * | 2023-04-21 | 2023-06-06 | 北京意胜生物科技有限公司 | 一种制备胰腺前体细胞的方法、培养基及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030124721A1 (en) * | 2001-11-09 | 2003-07-03 | Bentley Cheatham | Endocrine pancreas differentiation of adipose tissue-derived stromal cells and uses thereof |
| PT2733203T (pt) * | 2006-08-02 | 2019-01-23 | Technion Res & Dev Foundation | Métodos de expansão de células estminais embrionárias numa cultura de suspensão |
| JP5067949B2 (ja) * | 2006-11-09 | 2012-11-07 | 独立行政法人国立国際医療研究センター | 霊長類動物胚性幹細胞の培養及び継代方法、並びにその分化誘導方法 |
| US20090053182A1 (en) * | 2007-05-25 | 2009-02-26 | Medistem Laboratories, Inc. | Endometrial stem cells and methods of making and using same |
| CN104250632B (zh) * | 2007-07-01 | 2018-09-11 | 生命扫描有限公司 | 单个多能干细胞培养 |
| WO2009116951A2 (en) * | 2008-03-17 | 2009-09-24 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| US20100015711A1 (en) * | 2008-06-30 | 2010-01-21 | Janet Davis | Differentiation of Pluripotent Stem Cells |
| US8008075B2 (en) * | 2008-11-04 | 2011-08-30 | Viacyte, Inc. | Stem cell aggregate suspension compositions and methods of differentiation thereof |
| AU2010283229B2 (en) * | 2009-08-12 | 2015-04-02 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into neural precursor cells |
| WO2011158960A1 (en) * | 2010-06-15 | 2011-12-22 | Kyoto University | Method for selecting human induced pluripotent stem cells |
| CN108517310B (zh) * | 2010-08-31 | 2022-02-15 | 詹森生物科技公司 | 人胚胎干细胞的分化 |
| WO2012117333A1 (en) * | 2011-02-28 | 2012-09-07 | Stempeutics Research Malaysia Sdn Bhd | Isolation and expansion of adult stem cells, their therapeutic composition and uses thereof |
| WO2013056072A1 (en) * | 2011-10-13 | 2013-04-18 | Wisconsin Alumni Research Foundation | Generation of cardiomyocytes from human pluripotent stem cells |
| KR102203056B1 (ko) * | 2011-12-22 | 2021-01-14 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 단일 인슐린 호르몬 양성 세포로의 분화 |
| US10519422B2 (en) * | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
| WO2014106141A1 (en) * | 2012-12-31 | 2014-07-03 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent cells for differentiation into pancreatic endocrine cells |
| RU2689710C2 (ru) * | 2013-11-01 | 2019-05-29 | Янссен Байотек, Инк. | Суспендирование и кластеризация плюрипотентных стволовых клеток человека с целью их дифференцировки в панкреатические эндокринные клетки |
-
2014
- 2014-05-21 RU RU2016121409A patent/RU2689710C2/ru active
- 2014-05-21 SG SG11201603045VA patent/SG11201603045VA/en unknown
- 2014-05-21 KR KR1020167014409A patent/KR20160079072A/ko not_active Ceased
- 2014-05-21 EP EP14857034.4A patent/EP3063268A4/en not_active Withdrawn
- 2014-05-21 CN CN201480059910.5A patent/CN105793413A/zh active Pending
- 2014-05-21 CA CA2928639A patent/CA2928639A1/en not_active Abandoned
- 2014-05-21 MX MX2016005657A patent/MX2016005657A/es unknown
- 2014-05-21 WO PCT/US2014/038993 patent/WO2015065524A2/en not_active Ceased
- 2014-05-21 JP JP2016527338A patent/JP2016534731A/ja active Pending
- 2014-05-21 KR KR1020187034291A patent/KR20180128529A/ko not_active Abandoned
- 2014-05-21 AU AU2014342995A patent/AU2014342995C1/en not_active Ceased
- 2014-06-17 KR KR1020167014406A patent/KR20160079071A/ko not_active Abandoned
- 2014-06-17 AU AU2014343007A patent/AU2014343007C1/en not_active Ceased
- 2014-06-17 BR BR112016009393A patent/BR112016009393A8/pt not_active Application Discontinuation
- 2014-06-17 MX MX2016005658A patent/MX2016005658A/es unknown
- 2014-06-17 CA CA2928741A patent/CA2928741A1/en not_active Abandoned
- 2014-06-17 SG SG11201603047PA patent/SG11201603047PA/en unknown
- 2014-06-17 JP JP2016527450A patent/JP2017500013A/ja active Pending
- 2014-06-17 CN CN201480059902.0A patent/CN105683362A/zh active Pending
- 2014-06-17 RU RU2016121404A patent/RU2016121404A/ru not_active Application Discontinuation
- 2014-06-17 WO PCT/US2014/042796 patent/WO2015065537A1/en not_active Ceased
- 2014-06-17 KR KR1020187034483A patent/KR20180130001A/ko not_active Withdrawn
- 2014-06-17 EP EP14859059.9A patent/EP3063269A4/en not_active Withdrawn
-
2016
- 2016-04-27 PH PH12016500782A patent/PH12016500782A1/en unknown
- 2016-04-27 PH PH12016500783A patent/PH12016500783A1/en unknown
-
2018
- 2018-07-26 AU AU2018208707A patent/AU2018208707A1/en not_active Abandoned
- 2018-07-26 AU AU2018208717A patent/AU2018208717A1/en not_active Abandoned
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