SG11202006731VA - Method for differentiation of human pluripotent stem cell lines in suspension culture - Google Patents

Method for differentiation of human pluripotent stem cell lines in suspension culture

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Publication number
SG11202006731VA
SG11202006731VA SG11202006731VA SG11202006731VA SG11202006731VA SG 11202006731V A SG11202006731V A SG 11202006731VA SG 11202006731V A SG11202006731V A SG 11202006731VA SG 11202006731V A SG11202006731V A SG 11202006731VA SG 11202006731V A SG11202006731V A SG 11202006731VA
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SG
Singapore
Prior art keywords
differentiation
cell lines
stem cell
pluripotent stem
suspension culture
Prior art date
Application number
SG11202006731VA
Inventor
Jaichandran Sivalingam
Steve Oh
Shaul Reuveny
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Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of SG11202006731VA publication Critical patent/SG11202006731VA/en

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  • Health & Medical Sciences (AREA)
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  • Immunology (AREA)
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  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG11202006731VA 2018-01-18 2019-01-15 Method for differentiation of human pluripotent stem cell lines in suspension culture SG11202006731VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201800488W 2018-01-18
PCT/SG2019/050023 WO2019143292A1 (en) 2018-01-18 2019-01-15 Method for differentiation of human pluripotent stem cell lines in suspension culture

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SG11202006731VA true SG11202006731VA (en) 2020-08-28

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US (1) US20200399602A1 (en)
EP (1) EP3740566A4 (en)
JP (1) JP2021510527A (en)
CN (1) CN112041428B (en)
SG (1) SG11202006731VA (en)
WO (1) WO2019143292A1 (en)

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WO2020130068A1 (en) * 2018-12-20 2020-06-25 住友化学株式会社 Embryonic erythroblast-containing cell population and method for producing same, cell culture composition, and compound test method
JP2022545415A (en) * 2019-08-20 2022-10-27 アダプティミューン・リミテッド Culture medium for hematopoiesis induction
GB201911957D0 (en) * 2019-08-20 2019-10-02 Adaptimmune Ltd Methods of producing haemogenic progenitor cells from pluripotent stem cells
WO2021173458A1 (en) * 2020-02-28 2021-09-02 Purdue Research Foundation Generating aorta-gonad-mesonephros-like hematopoietic cells from human pluripotent stem cells under a defined condition
CN111321110A (en) * 2020-02-28 2020-06-23 上海市东方医院（同济大学附属东方医院） Method for differentiating human pluripotent stem cells into mesoderm
CN112226409B (en) * 2020-05-28 2023-07-21 东莞市东阳光生物药研发有限公司 Method for differentiating embryonic stem cells into CD34+ hematopoietic progenitor cells
TW202237826A (en) 2020-11-30 2022-10-01 瑞士商克里斯珀醫療股份公司 Gene-edited natural killer cells
EP4271798A1 (en) 2020-12-30 2023-11-08 CRISPR Therapeutics AG Compositions and methods for differentiating stem cells into nk cells
GB202102297D0 (en) * 2021-02-18 2021-04-07 Adaptimmune Ltd Methods of Producing Haemogenic Endothelial Cells from Pluripotent Stem Cells
CN113046318B (en) * 2021-04-13 2023-04-18 中国科学院深圳先进技术研究院 Culture medium and method for inducing pluripotent stem cells to differentiate into hematopoietic precursor cells
CN114181968B (en) * 2022-02-11 2022-07-19 北京干细胞与再生医学研究院 Preparation method and application of artificial blood progenitor cells with B lineage differentiation potential
WO2024059070A1 (en) * 2022-09-13 2024-03-21 R.P. Scherer Technologies, Llc Method of differentiation of pluripotent stem cells to hematopoietic precursor and stem cells
CN115927169B (en) * 2022-10-11 2023-08-11 再造再生医学科技(杭州)有限公司 For amplification of CD34 + Culture medium for hematopoietic stem cells and in vitro amplification of CD34 + Methods of hematopoietic stem cells
CN116064372A (en) * 2022-11-15 2023-05-05 上海交通大学 Method for preparing human ovary somatic cell-like cells
CN116769710A (en) * 2023-01-28 2023-09-19 深圳市寰宇生物科技有限公司 Macrophage differentiated from human induced pluripotent stem cells, and preparation method and application thereof
CN116640728B (en) * 2023-07-24 2023-10-20 呈诺再生医学科技(北京)有限公司 Application of RO8191 and AS2863619 in inducing generation of enucleated erythrocytes expressed AS human beta-globin

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