MX2016005657A - Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas. - Google Patents
Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas.Info
- Publication number
- MX2016005657A MX2016005657A MX2016005657A MX2016005657A MX2016005657A MX 2016005657 A MX2016005657 A MX 2016005657A MX 2016005657 A MX2016005657 A MX 2016005657A MX 2016005657 A MX2016005657 A MX 2016005657A MX 2016005657 A MX2016005657 A MX 2016005657A
- Authority
- MX
- Mexico
- Prior art keywords
- cells
- differentiation
- clustering
- suspension
- pluripotent stem
- Prior art date
Links
- 230000004069 differentiation Effects 0.000 title abstract 3
- 210000003890 endocrine cell Anatomy 0.000 title abstract 2
- 230000009996 pancreatic endocrine effect Effects 0.000 title abstract 2
- 210000001778 pluripotent stem cell Anatomy 0.000 title abstract 2
- 239000000725 suspension Substances 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 abstract 1
- 210000001705 ectoderm cell Anatomy 0.000 abstract 1
- 210000001900 endoderm Anatomy 0.000 abstract 1
- 210000002064 heart cell Anatomy 0.000 abstract 1
- 210000001704 mesoblast Anatomy 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
- C12N5/0075—General culture methods using substrates using microcarriers
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
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- C12N2500/00—Specific components of cell culture medium
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/117—Keratinocyte growth factors (KGF-1, i.e. FGF-7; KGF-2, i.e. FGF-12)
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- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C12N2501/19—Growth and differentiation factors [GDF]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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- C12N2501/41—Hedgehog proteins; Cyclopamine (inhibitor)
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- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361962158P | 2013-11-01 | 2013-11-01 | |
| US13/998,974 US10377989B2 (en) | 2012-12-31 | 2013-12-30 | Methods for suspension cultures of human pluripotent stem cells |
| PCT/US2014/038993 WO2015065524A2 (en) | 2013-11-01 | 2014-05-21 | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016005657A true MX2016005657A (es) | 2017-01-05 |
Family
ID=53004904
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016005657A MX2016005657A (es) | 2013-11-01 | 2014-05-21 | Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas. |
| MX2016005658A MX2016005658A (es) | 2013-11-01 | 2014-06-17 | Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016005658A MX2016005658A (es) | 2013-11-01 | 2014-06-17 | Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas. |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP3063268A4 (enExample) |
| JP (2) | JP2016534731A (enExample) |
| KR (4) | KR20180128529A (enExample) |
| CN (2) | CN105793413A (enExample) |
| AU (4) | AU2014342995C1 (enExample) |
| BR (1) | BR112016009393A8 (enExample) |
| CA (2) | CA2928639A1 (enExample) |
| MX (2) | MX2016005657A (enExample) |
| PH (2) | PH12016500783A1 (enExample) |
| RU (2) | RU2689710C2 (enExample) |
| SG (2) | SG11201603045VA (enExample) |
| WO (2) | WO2015065524A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2928639A1 (en) * | 2013-11-01 | 2015-05-07 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
| EP3474866A4 (en) * | 2016-06-23 | 2020-02-26 | Tithon Biotech, Inc. | CELLS EXPRESSING THE PARATHYROID HORMONE RECEPTOR 1 AND USES THEREOF |
| EP4595951A3 (en) | 2016-11-10 | 2025-08-27 | ViaCyte, Inc. | Pdx1 pancreatic endoderm cells in cell delivery devices |
| SG11201903428XA (en) * | 2016-11-16 | 2019-05-30 | Cynata Therapeutics Ltd | Pluripotent stem cell assay |
| US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
| JP2020527956A (ja) * | 2017-07-21 | 2020-09-17 | センマ・セラピューティクス・インコーポレーテッド | 幹細胞由来の膵臓ベータ細胞の再凝集 |
| JP7000896B2 (ja) * | 2017-08-23 | 2022-01-19 | 王子ホールディングス株式会社 | 細胞シート形成部材、細胞シート形成部材の製造方法、および、細胞シートの製造方法 |
| CN111836886A (zh) * | 2018-01-05 | 2020-10-27 | 血小板生源说股份有限公司 | 用于产生巨核细胞的组合物和方法 |
| SG11202006731VA (en) * | 2018-01-18 | 2020-08-28 | Agency Science Tech & Res | Method for differentiation of human pluripotent stem cell lines in suspension culture |
| KR102115360B1 (ko) * | 2018-05-30 | 2020-05-26 | 주식회사 바이블리오테카 | 성체 줄기세포 배양액 및 그 제조방법 |
| US10724052B2 (en) | 2018-09-07 | 2020-07-28 | Crispr Therapeutics Ag | Universal donor cells |
| CA3257300A1 (en) | 2019-05-31 | 2025-06-12 | W. L. Gore & Associates, Inc. | Cell encapsulation devices with controlled oxygen diffusion distances |
| WO2020243663A1 (en) | 2019-05-31 | 2020-12-03 | W. L. Gore & Associates, Inc. | A biocompatible membrane composite |
| AU2020284245B2 (en) | 2019-05-31 | 2023-10-05 | Viacyte, Inc. | A biocompatible membrane composite |
| WO2020243665A1 (en) | 2019-05-31 | 2020-12-03 | W. L. Gore & Associates, Inc. | A biocompatible membrane composite |
| CA3151339A1 (en) * | 2019-08-27 | 2021-03-04 | United Therapeutics Corporation | Methods and compositions for culturing alveolar cells |
| MX2022002783A (es) | 2019-09-05 | 2022-04-06 | Crispr Therapeutics Ag | Celulas donantes universales. |
| PH12022550542A1 (en) | 2019-09-05 | 2023-03-20 | Crispr Therapeutics Ag | Universal donor cells |
| CN114729323B (zh) * | 2019-11-22 | 2024-09-17 | 诺和诺德股份有限公司 | 旋转聚集的神经微球及其应用 |
| US11578309B2 (en) | 2020-12-31 | 2023-02-14 | Crispr Therapeutics Ag | Universal donor cells |
| WO2022203051A1 (ja) * | 2021-03-25 | 2022-09-29 | 株式会社カネカ | 多能性幹細胞集団の製造方法 |
| CN116218766A (zh) * | 2023-04-21 | 2023-06-06 | 北京意胜生物科技有限公司 | 一种制备胰腺前体细胞的方法、培养基及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ2004696A3 (cs) * | 2001-11-09 | 2005-02-16 | Artecel Sciences, Inc. | Endokrinní pankreatická diferenciace buněk stromatu odvozených z adipózní tkáně a její použití |
| EP2733203B1 (en) * | 2006-08-02 | 2018-10-10 | Technion Research & Development Foundation Ltd. | Methods of expanding embryonic stem cells in a suspension culture |
| US20110151554A1 (en) * | 2006-11-09 | 2011-06-23 | Akira Yuo | Method for culturing and subculturing primate embryonic stem cell, as well as method for inducing differentiation thereof |
| WO2008148105A1 (en) * | 2007-05-25 | 2008-12-04 | Medistem Laboratories, Inc. | Endometrial stem cells and methods of making and using same |
| KR20160054032A (ko) * | 2007-07-01 | 2016-05-13 | 라이프스캔, 인코포레이티드 | 단일 다분화성 줄기 세포 배양 |
| EP2271747B1 (en) * | 2008-03-17 | 2016-09-07 | Agency for Science, Technology And Research | Microcarriers for pluripotent stem cell culture |
| KR101651661B1 (ko) * | 2008-06-30 | 2016-08-26 | 얀센 바이오테크 인코포레이티드 | 만능 줄기 세포의 분화 |
| US8008075B2 (en) * | 2008-11-04 | 2011-08-30 | Viacyte, Inc. | Stem cell aggregate suspension compositions and methods of differentiation thereof |
| CN102597218B (zh) * | 2009-08-12 | 2017-10-27 | 国立大学法人京都大学 | 用于诱导多能干细胞分化成神经前体细胞的方法 |
| JP5936134B2 (ja) * | 2010-06-15 | 2016-06-15 | 国立大学法人京都大学 | ヒト人工多能性幹細胞の選択方法 |
| CA2809303C (en) * | 2010-08-31 | 2024-04-09 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| WO2012117333A1 (en) * | 2011-02-28 | 2012-09-07 | Stempeutics Research Malaysia Sdn Bhd | Isolation and expansion of adult stem cells, their therapeutic composition and uses thereof |
| US8951798B2 (en) * | 2011-10-13 | 2015-02-10 | Wisconsin Alumni Research Foundation | Generation of cardiomyocytes from human pluripotent stem cells |
| WO2013095953A1 (en) * | 2011-12-22 | 2013-06-27 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into single hormonal insulin positive cells |
| US10519422B2 (en) * | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
| EP4039798A1 (en) * | 2012-12-31 | 2022-08-10 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent cells |
| CA2928639A1 (en) * | 2013-11-01 | 2015-05-07 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
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2014
- 2014-05-21 CA CA2928639A patent/CA2928639A1/en not_active Abandoned
- 2014-05-21 KR KR1020187034291A patent/KR20180128529A/ko not_active Abandoned
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- 2014-05-21 AU AU2014342995A patent/AU2014342995C1/en not_active Ceased
- 2014-05-21 MX MX2016005657A patent/MX2016005657A/es unknown
- 2014-05-21 RU RU2016121409A patent/RU2689710C2/ru active
- 2014-05-21 EP EP14857034.4A patent/EP3063268A4/en not_active Withdrawn
- 2014-05-21 SG SG11201603045VA patent/SG11201603045VA/en unknown
- 2014-05-21 CN CN201480059910.5A patent/CN105793413A/zh active Pending
- 2014-05-21 WO PCT/US2014/038993 patent/WO2015065524A2/en not_active Ceased
- 2014-05-21 KR KR1020167014409A patent/KR20160079072A/ko not_active Ceased
- 2014-06-17 SG SG11201603047PA patent/SG11201603047PA/en unknown
- 2014-06-17 EP EP14859059.9A patent/EP3063269A4/en not_active Withdrawn
- 2014-06-17 JP JP2016527450A patent/JP2017500013A/ja active Pending
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- 2014-06-17 CN CN201480059902.0A patent/CN105683362A/zh active Pending
- 2014-06-17 WO PCT/US2014/042796 patent/WO2015065537A1/en not_active Ceased
- 2014-06-17 BR BR112016009393A patent/BR112016009393A8/pt not_active Application Discontinuation
- 2014-06-17 KR KR1020167014406A patent/KR20160079071A/ko not_active Abandoned
- 2014-06-17 RU RU2016121404A patent/RU2016121404A/ru not_active Application Discontinuation
- 2014-06-17 CA CA2928741A patent/CA2928741A1/en not_active Abandoned
- 2014-06-17 AU AU2014343007A patent/AU2014343007C1/en not_active Ceased
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2016
- 2016-04-27 PH PH12016500783A patent/PH12016500783A1/en unknown
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2018
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