JP2017114876A5 - - Google Patents

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Publication number
JP2017114876A5
JP2017114876A5 JP2017018192A JP2017018192A JP2017114876A5 JP 2017114876 A5 JP2017114876 A5 JP 2017114876A5 JP 2017018192 A JP2017018192 A JP 2017018192A JP 2017018192 A JP2017018192 A JP 2017018192A JP 2017114876 A5 JP2017114876 A5 JP 2017114876A5
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Japan
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group
nitrogen
oxygen
sulfur
membered
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JP2017018192A
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English (en)
Japanese (ja)
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JP6786410B2 (ja
JP2017114876A (ja
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JP2017018192A 2008-04-08 2017-02-03 トリテルペンであるサポニン、その合成法および使用 Active JP6786410B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4319708P 2008-04-08 2008-04-08
US61/043,197 2008-04-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015038239A Division JP2015134793A (ja) 2008-04-08 2015-02-27 トリテルペンであるサポニン、その合成法および使用

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019000534A Division JP6770596B2 (ja) 2008-04-08 2019-01-07 トリテルペンであるサポニン、その合成法および使用

Publications (3)

Publication Number Publication Date
JP2017114876A JP2017114876A (ja) 2017-06-29
JP2017114876A5 true JP2017114876A5 (enExample) 2017-10-12
JP6786410B2 JP6786410B2 (ja) 2020-11-18

Family

ID=40875147

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2011504157A Expired - Fee Related JP5706815B2 (ja) 2008-04-08 2009-04-08 トリテルペンであるサポニン、その合成法および使用
JP2015038239A Withdrawn JP2015134793A (ja) 2008-04-08 2015-02-27 トリテルペンであるサポニン、その合成法および使用
JP2017018192A Active JP6786410B2 (ja) 2008-04-08 2017-02-03 トリテルペンであるサポニン、その合成法および使用
JP2019000534A Active JP6770596B2 (ja) 2008-04-08 2019-01-07 トリテルペンであるサポニン、その合成法および使用
JP2020117691A Pending JP2020169206A (ja) 2008-04-08 2020-07-08 トリテルペンであるサポニン、その合成法および使用

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2011504157A Expired - Fee Related JP5706815B2 (ja) 2008-04-08 2009-04-08 トリテルペンであるサポニン、その合成法および使用
JP2015038239A Withdrawn JP2015134793A (ja) 2008-04-08 2015-02-27 トリテルペンであるサポニン、その合成法および使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2019000534A Active JP6770596B2 (ja) 2008-04-08 2019-01-07 トリテルペンであるサポニン、その合成法および使用
JP2020117691A Pending JP2020169206A (ja) 2008-04-08 2020-07-08 トリテルペンであるサポニン、その合成法および使用

Country Status (11)

Country Link
US (6) US8283456B2 (enExample)
EP (3) EP3357931B1 (enExample)
JP (5) JP5706815B2 (enExample)
KR (6) KR102453184B1 (enExample)
CN (2) CN102112484B (enExample)
AU (1) AU2009233757B2 (enExample)
CA (3) CA2993582C (enExample)
ES (1) ES2827804T3 (enExample)
HK (1) HK1211591A1 (enExample)
IL (4) IL208535A (enExample)
WO (1) WO2009126737A2 (enExample)

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CN102068446B (zh) * 2011-01-10 2013-08-21 武汉道一堂医药研究院 三萜皂苷化合物在制备抗病原微生物药物中的应用
AU2013204005B2 (en) * 2012-05-23 2015-04-16 Oncology Research International Limited Improved synthesis
US10517936B2 (en) 2013-01-04 2019-12-31 OBI Pharma., Inc. Vaccines with higher carbohydrate antigen density and novel saponin adjuvant
US10806119B2 (en) 2013-06-05 2020-10-20 Yeda Research And Development Co. Ltd. Plant with altered content of steroidal alkaloids
ES2914176T3 (es) 2013-09-17 2022-06-07 Obi Pharma Inc Composiciones de una vacuna glucídica para inducir respuestas inmunitarias y usos de las mismas en el tratamiento de cáncer
CA2950750C (en) 2014-05-30 2023-01-10 David Y. Gin Minimal saponin analogues, synthesis and use thereof
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
KR20180050339A (ko) 2015-09-04 2018-05-14 오비아이 파머 인코퍼레이티드 글리칸 어레이 및 사용 방법
US20180327436A1 (en) 2015-11-06 2018-11-15 Adjuvance Technologies, Inc. Triterpene saponin analogues
US10980894B2 (en) 2016-03-29 2021-04-20 Obi Pharma, Inc. Antibodies, pharmaceutical compositions and methods
EP3436482A4 (en) 2016-03-29 2020-03-11 OBI Pharma, Inc. ANTIBODIES, PHARMACEUTICAL COMPOSITIONS AND METHODS
JP7544465B2 (ja) 2016-04-22 2024-09-03 オービーアイ ファーマ，インコーポレイテッド グロボシリーズの抗原を介した免疫活性化又は免疫調節によるがん免疫療法
KR20190067765A (ko) 2016-07-27 2019-06-17 오비아이 파머 인코퍼레이티드 면역원성/치료 글리칸 조성물 및 그의 용도
TWI786054B (zh) 2016-07-29 2022-12-11 台灣浩鼎生技股份有限公司 人類抗體、醫藥組合物、及其方法
KR20190077103A (ko) 2016-11-21 2019-07-02 오비아이 파머 인코퍼레이티드 접합된 생물학적 분자, 제약 조성물 및 방법
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CN110869025A (zh) * 2017-04-13 2020-03-06 佐剂技术公司 三萜皂苷合成、中间体和佐剂组合
SG10202108075YA (en) * 2017-04-25 2021-09-29 Adjuvance Technologies Inc Triterpene saponin analogues
US20200164065A1 (en) * 2017-04-25 2020-05-28 Adjuvance Technologies, Inc. Triterpene saponin analogues
US11324821B2 (en) 2017-10-16 2022-05-10 Adjuvance Technologies, Inc. Triterpene saponin analogues
JP7304863B2 (ja) 2017-12-29 2023-07-07 グリコミメティクス， インコーポレイテッド Ｅ－セレクチンおよびガレクチン－３のヘテロ二機能性阻害剤
US12497429B2 (en) * 2018-03-20 2025-12-16 The Uab Research Foundation Saponin-based vaccine adjuvants
US11203645B2 (en) 2018-06-27 2021-12-21 Obi Pharma, Inc. Glycosynthase variants for glycoprotein engineering and methods of use
CN112969785A (zh) 2018-09-06 2021-06-15 耶达研究及发展有限公司 纤维素合酶样酶及其用途
US11547672B2 (en) 2018-09-14 2023-01-10 Massachusetts Institute Of Technology Nanoparticle vaccine adjuvant and methods of use thereof
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
AU2019416330A1 (en) 2018-12-27 2021-07-01 Glycomimetics, Inc. Galectin-3 inhibiting c-glycosides
US20220409721A1 (en) * 2019-11-05 2022-12-29 Adjuvance Technologies, Inc. Varicella zoster
US20230128815A1 (en) * 2020-03-23 2023-04-27 Adjuvance Technologies, Inc. Adjuvant compounds, salt forms, and formulations
WO2023052829A1 (en) * 2021-10-02 2023-04-06 Desert King Chile S.A A 3-o-monodesmosidic saponins extract, stable at physiological ph, method for preparing it from a quillaja plant extract cultured with a microbial consortium, uses and such microbial consortium
EP4190359A1 (en) 2021-12-03 2023-06-07 Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE Saponin-based adjuvants and vaccines
US20230190920A1 (en) 2021-12-19 2023-06-22 Massachusetts Institute Of Technology Compositions and methods for long-lasting germinal center responses to a priming immunization
WO2023139145A1 (en) 2022-01-19 2023-07-27 Asociación Centro De Investigación Cooperativa En Biociencias-Cic Biogune Saponin-based adjuvants and vaccines
WO2024218268A1 (en) 2023-04-20 2024-10-24 Asociación Centro De Investigación Cooperativa En Biociencias-Cic Biogune Saponin derivatives as adjuvants and photoaffinity probes

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KR102453184B1 (ko) * 2008-04-08 2022-10-07 슬로안-케테링인스티튜트퍼캔서리서치 트리테르펜 사포닌, 그의 합성 방법, 및 그의 용도
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CA2950750C (en) * 2014-05-30 2023-01-10 David Y. Gin Minimal saponin analogues, synthesis and use thereof

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