JP2017114876A5 - - Google Patents

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Publication number
JP2017114876A5
JP2017114876A5 JP2017018192A JP2017018192A JP2017114876A5 JP 2017114876 A5 JP2017114876 A5 JP 2017114876A5 JP 2017018192 A JP2017018192 A JP 2017018192A JP 2017018192 A JP2017018192 A JP 2017018192A JP 2017114876 A5 JP2017114876 A5 JP 2017114876A5
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JP
Japan
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group
nitrogen
oxygen
sulfur
membered
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JP2017018192A
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English (en)
Japanese (ja)
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JP2017114876A (ja
JP6786410B2 (ja
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Publication of JP2017114876A5 publication Critical patent/JP2017114876A5/ja
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JP2017018192A 2008-04-08 2017-02-03 トリテルペンであるサポニン、その合成法および使用 Active JP6786410B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4319708P 2008-04-08 2008-04-08
US61/043,197 2008-04-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015038239A Division JP2015134793A (ja) 2008-04-08 2015-02-27 トリテルペンであるサポニン、その合成法および使用

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019000534A Division JP6770596B2 (ja) 2008-04-08 2019-01-07 トリテルペンであるサポニン、その合成法および使用

Publications (3)

Publication Number Publication Date
JP2017114876A JP2017114876A (ja) 2017-06-29
JP2017114876A5 true JP2017114876A5 (enExample) 2017-10-12
JP6786410B2 JP6786410B2 (ja) 2020-11-18

Family

ID=40875147

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2011504157A Expired - Fee Related JP5706815B2 (ja) 2008-04-08 2009-04-08 トリテルペンであるサポニン、その合成法および使用
JP2015038239A Withdrawn JP2015134793A (ja) 2008-04-08 2015-02-27 トリテルペンであるサポニン、その合成法および使用
JP2017018192A Active JP6786410B2 (ja) 2008-04-08 2017-02-03 トリテルペンであるサポニン、その合成法および使用
JP2019000534A Active JP6770596B2 (ja) 2008-04-08 2019-01-07 トリテルペンであるサポニン、その合成法および使用
JP2020117691A Pending JP2020169206A (ja) 2008-04-08 2020-07-08 トリテルペンであるサポニン、その合成法および使用

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2011504157A Expired - Fee Related JP5706815B2 (ja) 2008-04-08 2009-04-08 トリテルペンであるサポニン、その合成法および使用
JP2015038239A Withdrawn JP2015134793A (ja) 2008-04-08 2015-02-27 トリテルペンであるサポニン、その合成法および使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2019000534A Active JP6770596B2 (ja) 2008-04-08 2019-01-07 トリテルペンであるサポニン、その合成法および使用
JP2020117691A Pending JP2020169206A (ja) 2008-04-08 2020-07-08 トリテルペンであるサポニン、その合成法および使用

Country Status (11)

Country Link
US (6) US8283456B2 (enExample)
EP (3) EP3868771A1 (enExample)
JP (5) JP5706815B2 (enExample)
KR (6) KR102256410B1 (enExample)
CN (2) CN104710487A (enExample)
AU (1) AU2009233757B2 (enExample)
CA (3) CA2993582C (enExample)
ES (1) ES2827804T3 (enExample)
HK (1) HK1211591A1 (enExample)
IL (4) IL208535A (enExample)
WO (1) WO2009126737A2 (enExample)

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CN111499679B (zh) 2013-01-04 2021-07-06 台湾浩鼎生技股份有限公司 具有较高碳水化合物抗原密度的疫苗及新颖皂素佐剂
US10806119B2 (en) 2013-06-05 2020-10-20 Yeda Research And Development Co. Ltd. Plant with altered content of steroidal alkaloids
BR112015032713B1 (pt) 2013-09-17 2023-03-21 Obi Pharma, Inc Composto, composição farmacêutica, uso de uma quantidade terapeuticamente efetiva da composição farmacêutica, e uso do composto
KR102424785B1 (ko) 2014-05-30 2022-07-25 메모리얼 슬로안 케터링 캔서 센터 최소 사포닌 유사체, 이의 합성법 및 용도
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US10935544B2 (en) 2015-09-04 2021-03-02 Obi Pharma, Inc. Glycan arrays and method of use
CN108778289B (zh) * 2015-11-06 2020-11-17 佐剂技术公司 三萜皂苷类似物
US10980894B2 (en) 2016-03-29 2021-04-20 Obi Pharma, Inc. Antibodies, pharmaceutical compositions and methods
BR112018070097A2 (pt) 2016-03-29 2019-02-12 Obi Pharma, Inc. anticorpo, hibridoma, composição farmacêutica, método para tratar câncer em um indivíduo, método para inibir a proliferação de células cancerígenas, método para diagnosticar o câncer em um indivíduo, método para tratar um paciente humano, método para fazer imagens de um indivíduo, conjugado de fármaco-anticorpo (adc), método para tratar câncer, anticorpo biespecífico e método para preparar uma população de anticorpos homogêneos
KR20230110820A (ko) 2016-04-22 2023-07-25 오비아이 파머 인코퍼레이티드 글로보 계열 항원을 통한 면역 활성화 또는 면역 조정에의한 암 면역요법
CN110072545A (zh) 2016-07-27 2019-07-30 台湾浩鼎生技股份有限公司 免疫原性/治疗性聚糖组合物及其用途
US11643456B2 (en) 2016-07-29 2023-05-09 Obi Pharma, Inc. Human antibodies, pharmaceutical compositions and methods
TWI822055B (zh) 2016-11-21 2023-11-11 台灣浩鼎生技股份有限公司 共軛生物分子、醫藥組成物及方法
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2018191598A1 (en) * 2017-04-13 2018-10-18 Adjuvance Technologies, Inc. Triterpene saponin synthesis, intermediates and adjuvant combinations
CA3061205A1 (en) 2017-04-25 2018-11-01 Memorial Sloan Kettering Cancer Center Triterpene saponin analogues
US20200164065A1 (en) * 2017-04-25 2020-05-28 Adjuvance Technologies, Inc. Triterpene saponin analogues
SG11202001826YA (en) * 2017-10-16 2020-03-30 Adjuvance Technologies Inc Triterpene saponin analogues
KR20200104889A (ko) 2017-12-29 2020-09-04 글리코미메틱스, 인크. E-셀렉틴 및 갈렉틴-3의 이종이기능성 억제제
US12497429B2 (en) * 2018-03-20 2025-12-16 The Uab Research Foundation Saponin-based vaccine adjuvants
TW202504930A (zh) 2018-06-27 2025-02-01 台灣浩鼎生技股份有限公司 用於糖蛋白工程的糖苷合成酶變體及其使用方法
SG11202102106RA (en) 2018-09-06 2021-04-29 Yeda Res & Dev Cellulose-synthase-like enzymes and uses thereof
WO2020055503A1 (en) 2018-09-14 2020-03-19 Massachusetts Institute Of Technology Nanoparticle vaccine adjuvant and methods of use thereof
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
CA3122321A1 (en) 2018-12-27 2020-07-02 Glycomimetics, Inc. Galectin-3 inhibiting c-glycosides
IL292796A (en) * 2019-11-05 2022-07-01 Adjuvance Tech Inc Varicella zoster immunogenic compositions and uses thereof
WO2021195024A1 (en) * 2020-03-23 2021-09-30 Adjuvance Technologies, Inc. Adjuvant compounds, salt forms, and formulations
KR20230044195A (ko) * 2020-06-24 2023-04-03 사프렘 테크놀로지스 비.브이. 항체-약물 접합체와 항체-사포닌 접합체의 조합물
WO2023052829A1 (en) * 2021-10-02 2023-04-06 Desert King Chile S.A A 3-o-monodesmosidic saponins extract, stable at physiological ph, method for preparing it from a quillaja plant extract cultured with a microbial consortium, uses and such microbial consortium
EP4190359A1 (en) 2021-12-03 2023-06-07 Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE Saponin-based adjuvants and vaccines
WO2023114570A1 (en) 2021-12-19 2023-06-22 Massachusetts Institute Of Technology Compositions and methods for long-lasting germinal center responses to a priming immunization
EP4466278A1 (en) 2022-01-19 2024-11-27 Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE Saponin-based adjuvants and vaccines
EP4698224A1 (en) 2023-04-20 2026-02-25 Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE Saponin derivatives as adjuvants and photoaffinity probes

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