JP2017114876A5 - - Google Patents

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Publication number
JP2017114876A5
JP2017114876A5 JP2017018192A JP2017018192A JP2017114876A5 JP 2017114876 A5 JP2017114876 A5 JP 2017114876A5 JP 2017018192 A JP2017018192 A JP 2017018192A JP 2017018192 A JP2017018192 A JP 2017018192A JP 2017114876 A5 JP2017114876 A5 JP 2017114876A5
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JP
Japan
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group
nitrogen
oxygen
sulfur
membered
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JP2017018192A
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English (en)
Japanese (ja)
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JP6786410B2 (ja
JP2017114876A (ja
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Publication of JP2017114876A5 publication Critical patent/JP2017114876A5/ja
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JP2017018192A 2008-04-08 2017-02-03 トリテルペンであるサポニン、その合成法および使用 Active JP6786410B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4319708P 2008-04-08 2008-04-08
US61/043,197 2008-04-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015038239A Division JP2015134793A (ja) 2008-04-08 2015-02-27 トリテルペンであるサポニン、その合成法および使用

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019000534A Division JP6770596B2 (ja) 2008-04-08 2019-01-07 トリテルペンであるサポニン、その合成法および使用

Publications (3)

Publication Number Publication Date
JP2017114876A JP2017114876A (ja) 2017-06-29
JP2017114876A5 true JP2017114876A5 (enExample) 2017-10-12
JP6786410B2 JP6786410B2 (ja) 2020-11-18

Family

ID=40875147

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2011504157A Expired - Fee Related JP5706815B2 (ja) 2008-04-08 2009-04-08 トリテルペンであるサポニン、その合成法および使用
JP2015038239A Withdrawn JP2015134793A (ja) 2008-04-08 2015-02-27 トリテルペンであるサポニン、その合成法および使用
JP2017018192A Active JP6786410B2 (ja) 2008-04-08 2017-02-03 トリテルペンであるサポニン、その合成法および使用
JP2019000534A Active JP6770596B2 (ja) 2008-04-08 2019-01-07 トリテルペンであるサポニン、その合成法および使用
JP2020117691A Pending JP2020169206A (ja) 2008-04-08 2020-07-08 トリテルペンであるサポニン、その合成法および使用

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2011504157A Expired - Fee Related JP5706815B2 (ja) 2008-04-08 2009-04-08 トリテルペンであるサポニン、その合成法および使用
JP2015038239A Withdrawn JP2015134793A (ja) 2008-04-08 2015-02-27 トリテルペンであるサポニン、その合成法および使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2019000534A Active JP6770596B2 (ja) 2008-04-08 2019-01-07 トリテルペンであるサポニン、その合成法および使用
JP2020117691A Pending JP2020169206A (ja) 2008-04-08 2020-07-08 トリテルペンであるサポニン、その合成法および使用

Country Status (11)

Country Link
US (6) US8283456B2 (enExample)
EP (3) EP2280987B1 (enExample)
JP (5) JP5706815B2 (enExample)
KR (6) KR102085687B1 (enExample)
CN (2) CN104710487A (enExample)
AU (1) AU2009233757B2 (enExample)
CA (3) CA2720771C (enExample)
ES (1) ES2827804T3 (enExample)
HK (1) HK1211591A1 (enExample)
IL (4) IL208535A (enExample)
WO (1) WO2009126737A2 (enExample)

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CA2897084C (en) 2013-01-04 2019-07-16 Cheng Der Tony Yu Vaccines with higher carbohydrate antigen density and novel saponin adjuvant
US10806119B2 (en) 2013-06-05 2020-10-20 Yeda Research And Development Co. Ltd. Plant with altered content of steroidal alkaloids
EP3046588B1 (en) 2013-09-17 2022-03-02 OBI Pharma, Inc. Compositions of a carbohydrate vaccine for inducing immune responses and uses thereof in cancer treatment
WO2015184451A1 (en) 2014-05-30 2015-12-03 Memorial Sloan-Kettering Cancer Center Minimal saponin analogues, synthesis and use thereof
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
EP3344806A4 (en) 2015-09-04 2019-03-20 OBI Pharma, Inc. GLYCANARRAYS AND METHOD OF USE
IL286493B (en) * 2015-11-06 2022-07-01 Memorial Sloan Kettering Cancer Center Triterpene saponin analogues, methods of producing same, compositions comprising same and uses thereof
AU2017239637A1 (en) 2016-03-29 2018-11-15 Obi Pharma, Inc. Antibodies, pharmaceutical compositions and methods
US10980894B2 (en) 2016-03-29 2021-04-20 Obi Pharma, Inc. Antibodies, pharmaceutical compositions and methods
IL262296B2 (en) 2016-04-22 2024-09-01 Obi Pharma Inc Cancer immunotherapy by immune activation or immune modulation via globo series antigens
KR20190067765A (ko) 2016-07-27 2019-06-17 오비아이 파머 인코퍼레이티드 면역원성/치료 글리칸 조성물 및 그의 용도
KR102528998B1 (ko) 2016-07-29 2023-05-03 오비아이 파머 인코퍼레이티드 인간 항체, 제약 조성물 및 방법
WO2018094414A1 (en) 2016-11-21 2018-05-24 Obi Pharma, Inc. Conjugated biological molecules, pharmaceutical compositions and methods
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
IL269963B2 (en) * 2017-04-13 2024-09-01 Adjuvance Tech Inc Triterpene saponin synthesis, intermediates and adjuvant combinations
CN110582282A (zh) 2017-04-25 2019-12-17 佐剂技术公司 三萜皂苷类似物
US20200164065A1 (en) * 2017-04-25 2020-05-28 Adjuvance Technologies, Inc. Triterpene saponin analogues
JP2020536946A (ja) * 2017-10-16 2020-12-17 アジュバンス・テクノロジーズ・インコーポレーテッド トリテルペンサポニン類似物
US11548908B2 (en) 2017-12-29 2023-01-10 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
US12497429B2 (en) * 2018-03-20 2025-12-16 The Uab Research Foundation Saponin-based vaccine adjuvants
TW202504930A (zh) 2018-06-27 2025-02-01 台灣浩鼎生技股份有限公司 用於糖蛋白工程的糖苷合成酶變體及其使用方法
JP2022500023A (ja) 2018-09-06 2022-01-04 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド セルロース合成酵素様酵素及びその使用
WO2020055503A1 (en) 2018-09-14 2020-03-19 Massachusetts Institute Of Technology Nanoparticle vaccine adjuvant and methods of use thereof
JP7547345B2 (ja) 2018-12-27 2024-09-09 グリコミメティクス， インコーポレイテッド ガレクチン－３阻害性ｃ－グリコシド
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
AU2020379738A1 (en) 2019-11-05 2022-04-14 Adjuvance Technologies, Inc. Varicella zoster
WO2021195024A1 (en) * 2020-03-23 2021-09-30 Adjuvance Technologies, Inc. Adjuvant compounds, salt forms, and formulations
WO2021261995A1 (en) * 2020-06-24 2021-12-30 Sapreme Technologies B.V. Combination of an antibody-drug conjugate and an antibody-saponin conjugate
US20250282811A1 (en) * 2021-10-02 2025-09-11 Desert King Chile S.A A 3-o-monodesmosidic saponins extract, stable at physiological ph, method for preparing it from a quillaja plant extract cultured with a microbial consortium, uses and such microbial consortium
EP4190359A1 (en) 2021-12-03 2023-06-07 Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE Saponin-based adjuvants and vaccines
WO2023114570A1 (en) 2021-12-19 2023-06-22 Massachusetts Institute Of Technology Compositions and methods for long-lasting germinal center responses to a priming immunization
EP4466278A1 (en) 2022-01-19 2024-11-27 Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE Saponin-based adjuvants and vaccines
WO2024218268A1 (en) 2023-04-20 2024-10-24 Asociación Centro De Investigación Cooperativa En Biociencias-Cic Biogune Saponin derivatives as adjuvants and photoaffinity probes
CN121852499A (zh) * 2026-03-17 2026-04-14 武汉糖智药业有限公司 Qs-7生物合成乙酰化的方法

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KR102085687B1 (ko) 2008-04-08 2020-03-06 슬로안-케테링인스티튜트퍼캔서리서치 트리테르펜 사포닌, 그의 합성 방법, 및 그의 용도
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