JP2016530236A5 - - Google Patents
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- Publication number
- JP2016530236A5 JP2016530236A5 JP2016524801A JP2016524801A JP2016530236A5 JP 2016530236 A5 JP2016530236 A5 JP 2016530236A5 JP 2016524801 A JP2016524801 A JP 2016524801A JP 2016524801 A JP2016524801 A JP 2016524801A JP 2016530236 A5 JP2016530236 A5 JP 2016530236A5
- Authority
- JP
- Japan
- Prior art keywords
- rotavirus
- protein
- adapter
- surface protein
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000702670 Rotavirus Species 0.000 claims description 81
- 102000018697 Membrane Proteins Human genes 0.000 claims description 57
- 108010052285 Membrane Proteins Proteins 0.000 claims description 57
- 102000004169 proteins and genes Human genes 0.000 claims description 41
- 108090000623 proteins and genes Proteins 0.000 claims description 41
- 239000002245 particle Substances 0.000 claims description 38
- 229920001184 polypeptide Polymers 0.000 claims description 37
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 37
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 37
- 238000000034 method Methods 0.000 claims description 23
- 150000007523 nucleic acids Chemical class 0.000 claims description 16
- 108020004707 nucleic acids Proteins 0.000 claims description 14
- 102000039446 nucleic acids Human genes 0.000 claims description 14
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 12
- 108020001507 fusion proteins Proteins 0.000 claims description 12
- 102000037865 fusion proteins Human genes 0.000 claims description 12
- 108700026244 Open Reading Frames Proteins 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 10
- 239000000725 suspension Substances 0.000 claims description 10
- 210000004027 cell Anatomy 0.000 claims description 7
- 239000001963 growth medium Substances 0.000 claims description 7
- 238000010367 cloning Methods 0.000 claims description 4
- 230000008014 freezing Effects 0.000 claims description 4
- 238000007710 freezing Methods 0.000 claims description 4
- 238000003384 imaging method Methods 0.000 claims description 4
- 238000001000 micrograph Methods 0.000 claims description 4
- 230000001902 propagating effect Effects 0.000 claims description 4
- 230000003612 virological effect Effects 0.000 claims description 4
- 102000000844 Cell Surface Receptors Human genes 0.000 claims description 3
- 108010001857 Cell Surface Receptors Proteins 0.000 claims description 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 2
- 239000012634 fragment Substances 0.000 claims description 2
- 239000002773 nucleotide Substances 0.000 claims description 2
- 125000003729 nucleotide group Chemical group 0.000 claims description 2
- 230000004927 fusion Effects 0.000 claims 2
- PXFBZOLANLWPMH-UHFFFAOYSA-N 16-Epiaffinine Natural products C1C(C2=CC=CC=C2N2)=C2C(=O)CC2C(=CC)CN(C)C1C2CO PXFBZOLANLWPMH-UHFFFAOYSA-N 0.000 description 1
- 230000004709 cell invasion Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000010845 search algorithm Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13175637 | 2013-07-08 | ||
| EP13175637.1 | 2013-07-08 | ||
| PCT/EP2014/064652 WO2015004158A1 (en) | 2013-07-08 | 2014-07-08 | Rotavirus particles with chimeric surface proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016530236A JP2016530236A (ja) | 2016-09-29 |
| JP2016530236A5 true JP2016530236A5 (enExample) | 2017-08-10 |
| JP6594306B2 JP6594306B2 (ja) | 2019-10-23 |
Family
ID=48747990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016524801A Active JP6594306B2 (ja) | 2013-07-08 | 2014-07-08 | キメラ表面タンパク質を有するロタウイルス粒子 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10192025B2 (enExample) |
| EP (1) | EP3019518B1 (enExample) |
| JP (1) | JP6594306B2 (enExample) |
| CN (1) | CN105518022B (enExample) |
| AU (1) | AU2014289274B2 (enExample) |
| CA (1) | CA2916827C (enExample) |
| ES (1) | ES2733279T3 (enExample) |
| MX (1) | MX367150B (enExample) |
| RU (1) | RU2698049C2 (enExample) |
| WO (1) | WO2015004158A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202000101T1 (it) * | 2008-10-10 | 2020-03-13 | Childrens Medical Center | Vaccino con trimero di env di hiv-1 stabilizzato biochimicamente |
| CN105263506B (zh) | 2013-01-07 | 2018-03-09 | 贝丝以色列女执事医疗中心 | 稳定的人免疫缺陷病毒(HIV)包膜(EnV)三聚体疫苗及其使用方法 |
| US10174292B2 (en) | 2015-03-20 | 2019-01-08 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| WO2017071713A1 (en) * | 2015-10-30 | 2017-05-04 | University Of Copenhagen | Virus like particle with efficient epitope display |
| MA44418B1 (fr) * | 2017-03-02 | 2021-11-30 | Intelligent Virus Imaging Inc | Procédé permettant la mesure quantitative de contenu particulaire à l'aide d'une imagerie à l'état hydraté |
| CN109627295B (zh) * | 2018-12-29 | 2020-08-04 | 四川大学 | 一种通用型狂犬病相关病毒g蛋白胞外段的制备方法 |
| CN110144334B (zh) * | 2019-05-05 | 2021-03-16 | 中国水产科学研究院长江水产研究所 | 一种共表达草鱼呼肠孤病毒外衣壳蛋白vp4和vp35的重组杆状病毒的制备方法和应用 |
| CN110408637B (zh) * | 2019-08-08 | 2020-12-25 | 中国水产科学研究院长江水产研究所 | 一种草鱼出血病酵母口服疫苗及应用 |
| CN114316009B (zh) * | 2020-09-29 | 2023-04-25 | 上海交通大学 | 一种能够结合多种病毒的蛋白及其应用 |
| CN115044597A (zh) * | 2022-07-22 | 2022-09-13 | 态创生物科技(广州)有限公司 | 基于噬菌体展示和蛋白酶切割的寡肽表达和提纯方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0235754A2 (en) | 1986-03-04 | 1987-09-09 | Abbott Laboratories | Composition and methods of use for a lacZ rotavirus fusion protein |
| JP3055687B2 (ja) * | 1987-08-10 | 2000-06-26 | ザ ユニバーシティー オブ メルボルン | Ｖｐ７をコードするヒトロタウイルス血清型４遺伝子９の分子クローニング、糖タンパク質特異的主要外部カプシド中和及びワクチンに使用するためのｖｐ７及びそのフラグメントの発現 |
| ZA929418B (en) * | 1991-12-06 | 1993-06-07 | Whitehead Biomedical Inst | Recombinant vaccines and method of producing same. |
| WO2006007555A2 (en) * | 2004-07-01 | 2006-01-19 | Children's Medical Center Corporation ¨ | Rotavirus antigens |
| US7655439B2 (en) | 2005-09-09 | 2010-02-02 | Zymogenetics, Inc. | Trimerizing polypeptides |
| KR101502619B1 (ko) * | 2007-03-29 | 2015-03-16 | 한국엠에스디 유한회사 | 인간로타바이러스의 ｖｐ７ 유전자 및 이에 특이적인프라이머 또는 프로브를 포함하는 인간로타바이러스 감염증진단용 조성물 |
| CN102465137B (zh) * | 2010-11-05 | 2014-03-12 | 上海生物制品研究所有限责任公司 | 表达轮状病毒类表达颗粒的毕赤酵母、其制备方法及用途 |
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2014
- 2014-07-08 AU AU2014289274A patent/AU2014289274B2/en active Active
- 2014-07-08 ES ES14736835T patent/ES2733279T3/es active Active
- 2014-07-08 CA CA2916827A patent/CA2916827C/en active Active
- 2014-07-08 JP JP2016524801A patent/JP6594306B2/ja active Active
- 2014-07-08 WO PCT/EP2014/064652 patent/WO2015004158A1/en not_active Ceased
- 2014-07-08 EP EP14736835.1A patent/EP3019518B1/en active Active
- 2014-07-08 CN CN201480049500.2A patent/CN105518022B/zh active Active
- 2014-07-08 MX MX2016000075A patent/MX367150B/es active IP Right Grant
- 2014-07-08 RU RU2016103770A patent/RU2698049C2/ru active
- 2014-07-08 US US14/900,829 patent/US10192025B2/en active Active