CN105518022B - 具有嵌合表面蛋白的轮状病毒颗粒 - Google Patents

具有嵌合表面蛋白的轮状病毒颗粒 Download PDF

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CN105518022B
CN105518022B CN201480049500.2A CN201480049500A CN105518022B CN 105518022 B CN105518022 B CN 105518022B CN 201480049500 A CN201480049500 A CN 201480049500A CN 105518022 B CN105518022 B CN 105518022B
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rotavirus
protein
particles
adaptor
heterologous
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CN105518022A (zh
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P·R·道米策
N·格利高里夫
S·哈里森
J·潘
E·塞滕布里
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Novartis AG
Boston Childrens Hospital
Brandeis University
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Boston Childrens Hospital
Brandeis University
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    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/42—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a HA(hemagglutinin)-tag
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    • C07K2319/00—Fusion polypeptide
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12323—Virus like particles [VLP]
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    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12351—Methods of production or purification of viral material

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CN201480049500.2A 2013-07-08 2014-07-08 具有嵌合表面蛋白的轮状病毒颗粒 Active CN105518022B (zh)

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EP13175637 2013-07-08
EP13175637.1 2013-07-08
PCT/EP2014/064652 WO2015004158A1 (en) 2013-07-08 2014-07-08 Rotavirus particles with chimeric surface proteins

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CN105518022A CN105518022A (zh) 2016-04-20
CN105518022B true CN105518022B (zh) 2020-08-18

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US (1) US10192025B2 (enExample)
EP (1) EP3019518B1 (enExample)
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CN (1) CN105518022B (enExample)
AU (1) AU2014289274B2 (enExample)
CA (1) CA2916827C (enExample)
ES (1) ES2733279T3 (enExample)
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SMT202000101T1 (it) * 2008-10-10 2020-03-13 Childrens Medical Center Vaccino con trimero di env di hiv-1 stabilizzato biochimicamente
CN105263506B (zh) 2013-01-07 2018-03-09 贝丝以色列女执事医疗中心 稳定的人免疫缺陷病毒(HIV)包膜(EnV)三聚体疫苗及其使用方法
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
WO2017071713A1 (en) * 2015-10-30 2017-05-04 University Of Copenhagen Virus like particle with efficient epitope display
MA44418B1 (fr) * 2017-03-02 2021-11-30 Intelligent Virus Imaging Inc Procédé permettant la mesure quantitative de contenu particulaire à l'aide d'une imagerie à l'état hydraté
CN109627295B (zh) * 2018-12-29 2020-08-04 四川大学 一种通用型狂犬病相关病毒g蛋白胞外段的制备方法
CN110144334B (zh) * 2019-05-05 2021-03-16 中国水产科学研究院长江水产研究所 一种共表达草鱼呼肠孤病毒外衣壳蛋白vp4和vp35的重组杆状病毒的制备方法和应用
CN110408637B (zh) * 2019-08-08 2020-12-25 中国水产科学研究院长江水产研究所 一种草鱼出血病酵母口服疫苗及应用
CN114316009B (zh) * 2020-09-29 2023-04-25 上海交通大学 一种能够结合多种病毒的蛋白及其应用
CN115044597A (zh) * 2022-07-22 2022-09-13 态创生物科技(广州)有限公司 基于噬菌体展示和蛋白酶切割的寡肽表达和提纯方法

Citations (1)

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WO2015004158A1 (en) 2015-01-15
JP6594306B2 (ja) 2019-10-23
US20160188790A1 (en) 2016-06-30
MX367150B (es) 2019-08-07
JP2016530236A (ja) 2016-09-29
RU2698049C2 (ru) 2019-08-21
CN105518022A (zh) 2016-04-20
RU2016103770A3 (enExample) 2018-07-25
MX2016000075A (es) 2016-07-19
RU2016103770A (ru) 2017-08-11
EP3019518A1 (en) 2016-05-18
US10192025B2 (en) 2019-01-29
EP3019518B1 (en) 2019-04-03
AU2014289274B2 (en) 2018-11-15
ES2733279T3 (es) 2019-11-28
CA2916827C (en) 2021-11-02
AU2014289274A1 (en) 2016-02-18
CA2916827A1 (en) 2015-01-15

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