JP2016529230A5 - - Google Patents

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JP2016529230A5
JP2016529230A5 JP2016525825A JP2016525825A JP2016529230A5 JP 2016529230 A5 JP2016529230 A5 JP 2016529230A5 JP 2016525825 A JP2016525825 A JP 2016525825A JP 2016525825 A JP2016525825 A JP 2016525825A JP 2016529230 A5 JP2016529230 A5 JP 2016529230A5
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oligonucleotide
ligand
linker
biologically active
conjugate
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JP6702862B2 (ja
JP2016529230A (ja
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Priority claimed from PCT/US2014/046425 external-priority patent/WO2015006740A2/en
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Priority to JP2020081749A priority Critical patent/JP7296916B2/ja
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Publication of JP6702862B2 publication Critical patent/JP6702862B2/ja
Priority to JP2023060071A priority patent/JP7676460B2/ja
Priority to JP2025075070A priority patent/JP2025107295A/ja
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JP2016525825A 2013-07-11 2014-07-11 オリゴヌクレオチド−リガンドコンジュゲートおよびそれらの調製方法 Active JP6702862B2 (ja)

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JP2020081749A JP7296916B2 (ja) 2013-07-11 2020-05-07 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法
JP2023060071A JP7676460B2 (ja) 2013-07-11 2023-04-03 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法
JP2025075070A JP2025107295A (ja) 2013-07-11 2025-04-30 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法

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US201361845279P 2013-07-11 2013-07-11
US61/845,279 2013-07-11
PCT/US2014/046425 WO2015006740A2 (en) 2013-07-11 2014-07-11 Oligonucleotide-ligand conjugates and process for their preparation

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JP2020081749A Division JP7296916B2 (ja) 2013-07-11 2020-05-07 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法

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JP2016529230A JP2016529230A (ja) 2016-09-23
JP2016529230A5 true JP2016529230A5 (enExample) 2017-08-24
JP6702862B2 JP6702862B2 (ja) 2020-06-03

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JP2016525825A Active JP6702862B2 (ja) 2013-07-11 2014-07-11 オリゴヌクレオチド−リガンドコンジュゲートおよびそれらの調製方法
JP2020081749A Active JP7296916B2 (ja) 2013-07-11 2020-05-07 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法
JP2023060071A Active JP7676460B2 (ja) 2013-07-11 2023-04-03 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法
JP2025075070A Pending JP2025107295A (ja) 2013-07-11 2025-04-30 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法

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JP2020081749A Active JP7296916B2 (ja) 2013-07-11 2020-05-07 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法
JP2023060071A Active JP7676460B2 (ja) 2013-07-11 2023-04-03 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法
JP2025075070A Pending JP2025107295A (ja) 2013-07-11 2025-04-30 オリゴヌクレオチド-リガンドコンジュゲートおよびそれらの調製方法

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US (3) US10808246B2 (enExample)
EP (3) EP3019200B1 (enExample)
JP (4) JP6702862B2 (enExample)
AU (4) AU2014287002A1 (enExample)
CA (2) CA2917161C (enExample)
DK (1) DK3019200T3 (enExample)
WO (1) WO2015006740A2 (enExample)

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