JP2016528179A5 - - Google Patents

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JP2016528179A5
JP2016528179A5 JP2016519576A JP2016519576A JP2016528179A5 JP 2016528179 A5 JP2016528179 A5 JP 2016528179A5 JP 2016519576 A JP2016519576 A JP 2016519576A JP 2016519576 A JP2016519576 A JP 2016519576A JP 2016528179 A5 JP2016528179 A5 JP 2016528179A5
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crystal
diffraction pattern
ray diffraction
compound
formula
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JP6998655B2 (ja
JP2016528179A (ja
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JP2016519576A 2013-06-10 2014-06-09 製造方法及びmdm2阻害剤の結晶形 Active JP6998655B2 (ja)

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JP2020084989A JP6891322B2 (ja) 2013-06-10 2020-05-14 製造方法及びmdm2阻害剤の結晶形

Applications Claiming Priority (3)

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US201361833196P 2013-06-10 2013-06-10
US61/833,196 2013-06-10
PCT/US2014/041594 WO2014200937A1 (en) 2013-06-10 2014-06-09 Processes of making and crystalline forms of a mdm2 inhibitor

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JP2020084989A Division JP6891322B2 (ja) 2013-06-10 2020-05-14 製造方法及びmdm2阻害剤の結晶形

Publications (3)

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JP2016528179A JP2016528179A (ja) 2016-09-15
JP2016528179A5 true JP2016528179A5 (enExample) 2017-07-20
JP6998655B2 JP6998655B2 (ja) 2022-02-04

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JP2016519576A Active JP6998655B2 (ja) 2013-06-10 2014-06-09 製造方法及びmdm2阻害剤の結晶形
JP2020084989A Active JP6891322B2 (ja) 2013-06-10 2020-05-14 製造方法及びmdm2阻害剤の結晶形
JP2021087378A Active JP7263439B2 (ja) 2013-06-10 2021-05-25 製造方法及びmdm2阻害剤の結晶形
JP2023064715A Pending JP2023089126A (ja) 2013-06-10 2023-04-12 製造方法及びmdm2阻害剤の結晶形
JP2025029906A Pending JP2025084856A (ja) 2013-06-10 2025-02-27 製造方法及びmdm2阻害剤の結晶形

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JP2020084989A Active JP6891322B2 (ja) 2013-06-10 2020-05-14 製造方法及びmdm2阻害剤の結晶形
JP2021087378A Active JP7263439B2 (ja) 2013-06-10 2021-05-25 製造方法及びmdm2阻害剤の結晶形
JP2023064715A Pending JP2023089126A (ja) 2013-06-10 2023-04-12 製造方法及びmdm2阻害剤の結晶形
JP2025029906A Pending JP2025084856A (ja) 2013-06-10 2025-02-27 製造方法及びmdm2阻害剤の結晶形

Country Status (38)

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US (10) US9376386B2 (enExample)
EP (3) EP3805232B1 (enExample)
JP (5) JP6998655B2 (enExample)
KR (4) KR20240159641A (enExample)
CN (3) CN110627708A (enExample)
AP (1) AP2015008891A0 (enExample)
AR (3) AR096582A1 (enExample)
AU (5) AU2014278428B2 (enExample)
BR (2) BR122020003153B1 (enExample)
CA (4) CA3201958A1 (enExample)
CL (3) CL2015003589A1 (enExample)
CR (2) CR20210290A (enExample)
CY (1) CY1123661T1 (enExample)
DK (1) DK3008039T3 (enExample)
EA (3) EA202091612A1 (enExample)
ES (2) ES3072074T3 (enExample)
HR (1) HRP20202065T1 (enExample)
HU (1) HUE053047T2 (enExample)
IL (4) IL297860A (enExample)
JO (2) JO3768B1 (enExample)
LT (1) LT3008039T (enExample)
MA (3) MA53572A1 (enExample)
MX (2) MX379872B (enExample)
MY (2) MY194848A (enExample)
NZ (1) NZ714821A (enExample)
PE (2) PE20160113A1 (enExample)
PH (2) PH12020550916A1 (enExample)
PL (1) PL3008039T3 (enExample)
PT (1) PT3008039T (enExample)
RS (1) RS61192B1 (enExample)
SG (2) SG11201509896VA (enExample)
SI (1) SI3008039T1 (enExample)
SM (1) SMT202100013T1 (enExample)
TN (1) TN2015000521A1 (enExample)
TW (3) TWI698428B (enExample)
UA (2) UA121301C2 (enExample)
UY (2) UY40179A (enExample)
WO (1) WO2014200937A1 (enExample)

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WO2014151863A1 (en) 2013-03-14 2014-09-25 Amgen Inc. Heteroaryl acid morpholinone compounds as mdm2 inhibitors for the treatment of cancer
MA53572A1 (fr) 2013-06-10 2021-10-29 Amgen Inc Procédés de production et formes cristallines d'un inhibiteur mdm2
MY192088A (en) 2013-11-11 2022-07-26 Amgen Inc Combinantion therapy including an mdm2 inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers
CN109152843A (zh) 2016-05-20 2019-01-04 豪夫迈·罗氏有限公司 Protac抗体缀合物及其使用方法
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JP2023539867A (ja) 2020-08-27 2023-09-20 大塚製薬株式会社 Mdm2アンタゴニストを用いた癌治療に関するバイオマーカー
WO2022183006A1 (en) 2021-02-25 2022-09-01 Mayo Foundation For Medical Education And Research Compounds for programmable protein degradation and methods of use for the disease treatment
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EP4398903A4 (en) * 2021-09-09 2025-07-16 Kartos Therapeutics METHODS FOR TREATING CANCER DEPENDENT ON MYC GENE EXPRESSION
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CN115925589A (zh) * 2022-12-26 2023-04-07 诚达药业股份有限公司 一种脂肪族亚磺酸钙盐及其制备方法
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