JP2016514727A5 - - Google Patents

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JP2016514727A5
JP2016514727A5 JP2016504377A JP2016504377A JP2016514727A5 JP 2016514727 A5 JP2016514727 A5 JP 2016514727A5 JP 2016504377 A JP2016504377 A JP 2016504377A JP 2016504377 A JP2016504377 A JP 2016504377A JP 2016514727 A5 JP2016514727 A5 JP 2016514727A5
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alkyl
aryl
heteroaryl
heterocyclyl
cycloalkyl
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JP2016514727A (ja
JP6360881B2 (ja
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Priority claimed from PCT/US2014/031442 external-priority patent/WO2014153509A1/en
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JP2016504377A 2013-03-22 2014-03-21 触媒的ｍｔｏｒｃ１／２阻害薬及びオーロラａキナーゼの選択的阻害薬の組合せ Active JP6360881B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361804314P 2013-03-22 2013-03-22
US61/804,314 2013-03-22
PCT/US2014/031442 WO2014153509A1 (en) 2013-03-22 2014-03-21 Combination of catalytic mtorc 1/2 inhibitors and selective inhibitors of aurora a kinase

Publications (3)

Publication Number Publication Date
JP2016514727A JP2016514727A (ja) 2016-05-23
JP2016514727A5 true JP2016514727A5 (enExample) 2017-04-27
JP6360881B2 JP6360881B2 (ja) 2018-07-18

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JP2016504377A Active JP6360881B2 (ja) 2013-03-22 2014-03-21 触媒的ｍｔｏｒｃ１／２阻害薬及びオーロラａキナーゼの選択的阻害薬の組合せ

Country Status (6)

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US (2) US9724354B2 (enExample)
EP (1) EP2976086B1 (enExample)
JP (1) JP6360881B2 (enExample)
CN (1) CN105209042B (enExample)
CA (1) CA2907726A1 (enExample)
WO (1) WO2014153509A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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AU2016342027B2 (en) * 2015-10-23 2021-05-13 Navitor Pharmaceuticals, Inc. Modulators of Sestrin-GATOR2 interaction and uses thereof
SI3442535T1 (sl) 2016-04-15 2023-01-31 Cancer Research Technology Limited Heterociklične spojine kot zaviralci RET-kinaze
WO2017178844A1 (en) 2016-04-15 2017-10-19 Cancer Research Technology Limited Heterocyclic compounds as ret kinase inhibitors
ITUA20164278A1 (it) * 2016-06-10 2017-12-10 International Soc For Drug Development S R L COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA
GB201705971D0 (en) 2017-04-13 2017-05-31 Cancer Res Tech Ltd Inhibitor compounds
WO2020146779A1 (en) * 2019-01-11 2020-07-16 The Regents Of The University Of California mTORC1 INHIBITORS FOR ACTIVATING AUTOPHAGY
US20240067655A1 (en) * 2020-11-13 2024-02-29 Neuron23, Inc. Kinase modulators and methods of use thereof
CN112782402A (zh) * 2020-12-11 2021-05-11 南京市儿童医院 一种利用mk-5108阻断aurka来减轻肾纤维化的方法

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