JP2016513110A5 - - Google Patents

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Publication number
JP2016513110A5
JP2016513110A5 JP2015558162A JP2015558162A JP2016513110A5 JP 2016513110 A5 JP2016513110 A5 JP 2016513110A5 JP 2015558162 A JP2015558162 A JP 2015558162A JP 2015558162 A JP2015558162 A JP 2015558162A JP 2016513110 A5 JP2016513110 A5 JP 2016513110A5
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JP
Japan
Prior art keywords
pharmaceutical composition
modified oligonucleotide
wing
fragment
wing fragment
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JP2015558162A
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English (en)
Japanese (ja)
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JP2016513110A (ja
JP6313789B2 (ja
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Priority claimed from PCT/US2014/016546 external-priority patent/WO2014127268A2/en
Publication of JP2016513110A publication Critical patent/JP2016513110A/ja
Publication of JP2016513110A5 publication Critical patent/JP2016513110A5/ja
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JP2015558162A 2013-02-14 2014-02-14 リポタンパク質リパーゼ欠損(lpld)集団におけるアポリポタンパク質c−iii(apociii)発現の調節 Active JP6313789B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361764969P 2013-02-14 2013-02-14
US61/764,969 2013-02-14
US201361880779P 2013-09-20 2013-09-20
US61/880,779 2013-09-20
PCT/US2014/016546 WO2014127268A2 (en) 2013-02-14 2014-02-14 Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018054633A Division JP6681422B2 (ja) 2013-02-14 2018-03-22 リポタンパク質リパーゼ欠損(lpld)集団におけるアポリポタンパク質c−iii(apociii)発現の調節

Publications (3)

Publication Number Publication Date
JP2016513110A JP2016513110A (ja) 2016-05-12
JP2016513110A5 true JP2016513110A5 (enExample) 2017-03-16
JP6313789B2 JP6313789B2 (ja) 2018-04-18

Family

ID=51354689

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2015558162A Active JP6313789B2 (ja) 2013-02-14 2014-02-14 リポタンパク質リパーゼ欠損(lpld)集団におけるアポリポタンパク質c−iii(apociii)発現の調節
JP2018054633A Active JP6681422B2 (ja) 2013-02-14 2018-03-22 リポタンパク質リパーゼ欠損(lpld)集団におけるアポリポタンパク質c−iii(apociii)発現の調節
JP2020050456A Withdrawn JP2020111594A (ja) 2013-02-14 2020-03-23 リポタンパク質リパーゼ欠損(lpld)集団におけるアポリポタンパク質c−iii(apociii)発現の調節

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018054633A Active JP6681422B2 (ja) 2013-02-14 2018-03-22 リポタンパク質リパーゼ欠損(lpld)集団におけるアポリポタンパク質c−iii(apociii)発現の調節
JP2020050456A Withdrawn JP2020111594A (ja) 2013-02-14 2020-03-23 リポタンパク質リパーゼ欠損(lpld)集団におけるアポリポタンパク質c−iii(apociii)発現の調節

Country Status (16)

Country Link
US (4) US9593333B2 (enExample)
EP (2) EP2956176B1 (enExample)
JP (3) JP6313789B2 (enExample)
KR (2) KR20200123263A (enExample)
CN (2) CN108743943A (enExample)
AU (3) AU2014216137B2 (enExample)
BR (1) BR112015019515A8 (enExample)
CA (2) CA3170716A1 (enExample)
DK (1) DK2956176T3 (enExample)
ES (2) ES2961686T3 (enExample)
IL (2) IL240338B (enExample)
MX (2) MX368155B (enExample)
NZ (1) NZ631119A (enExample)
RU (2) RU2018121529A (enExample)
WO (1) WO2014127268A2 (enExample)
ZA (1) ZA201505628B (enExample)

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PL2992098T3 (pl) 2013-05-01 2019-09-30 Ionis Pharmaceuticals, Inc. Kompozycje i sposoby modulowania ekspresji hbv i ttr
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MX2020004512A (es) 2017-10-31 2020-08-13 Anticuerpos anti apolipoproteina c-iii (anti-apoc3) y metodos de uso de los mismos.
US10538583B2 (en) 2017-10-31 2020-01-21 Staten Biotechnology B.V. Anti-APOC3 antibodies and compositions thereof
JP7427608B2 (ja) 2018-05-11 2024-02-05 ウェイブ ライフ サイエンシズ リミテッド オリゴヌクレオチド組成物及びその使用方法
WO2022072244A1 (en) * 2020-10-02 2022-04-07 Ionis Pharmaceuticals, Inc. Methods for reducing apociii expression
CN116814621B (zh) * 2022-08-05 2025-09-09 厦门甘宝利生物医药有限公司 一种抑制apoc3基因表达的rna抑制剂及其应用
WO2025110984A1 (en) * 2023-11-21 2025-05-30 Hydrogene Therapeutics, Inc. Compositions and methods for treating wilson's disease

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