AU2014216137B2 - Modulation of Apolipoprotein C-III (ApoCIII) expression in lipoprotein lipase deficient (LPLD) populations - Google Patents

Modulation of Apolipoprotein C-III (ApoCIII) expression in lipoprotein lipase deficient (LPLD) populations Download PDF

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Publication number
AU2014216137B2
AU2014216137B2 AU2014216137A AU2014216137A AU2014216137B2 AU 2014216137 B2 AU2014216137 B2 AU 2014216137B2 AU 2014216137 A AU2014216137 A AU 2014216137A AU 2014216137 A AU2014216137 A AU 2014216137A AU 2014216137 B2 AU2014216137 B2 AU 2014216137B2
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certain embodiments
apociii
wing segment
animal
lpld
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AU2014216137A1 (en
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Veronica J. Alexander
Nicholas J. Viney
Joseph L. Witztum
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Ionis Pharmaceuticals Inc
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Ionis Pharmaceuticals Inc
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AU2014216137A 2013-02-14 2014-02-14 Modulation of Apolipoprotein C-III (ApoCIII) expression in lipoprotein lipase deficient (LPLD) populations Active AU2014216137B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2018211325A AU2018211325B2 (en) 2013-02-14 2018-08-03 Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations
AU2020202300A AU2020202300A1 (en) 2013-02-14 2020-03-31 Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361764969P 2013-02-14 2013-02-14
US61/764,969 2013-02-14
US201361880779P 2013-09-20 2013-09-20
US61/880,779 2013-09-20
PCT/US2014/016546 WO2014127268A2 (en) 2013-02-14 2014-02-14 Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations

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Application Number Title Priority Date Filing Date
AU2018211325A Division AU2018211325B2 (en) 2013-02-14 2018-08-03 Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations

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AU2014216137A1 AU2014216137A1 (en) 2015-08-20
AU2014216137B2 true AU2014216137B2 (en) 2018-05-10

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AU2014216137A Active AU2014216137B2 (en) 2013-02-14 2014-02-14 Modulation of Apolipoprotein C-III (ApoCIII) expression in lipoprotein lipase deficient (LPLD) populations
AU2018211325A Active AU2018211325B2 (en) 2013-02-14 2018-08-03 Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations
AU2020202300A Withdrawn AU2020202300A1 (en) 2013-02-14 2020-03-31 Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations

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AU2018211325A Active AU2018211325B2 (en) 2013-02-14 2018-08-03 Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations
AU2020202300A Withdrawn AU2020202300A1 (en) 2013-02-14 2020-03-31 Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations

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US (4) US9593333B2 (enExample)
EP (2) EP3400947B1 (enExample)
JP (3) JP6313789B2 (enExample)
KR (2) KR102169899B1 (enExample)
CN (2) CN108743943A (enExample)
AU (3) AU2014216137B2 (enExample)
BR (1) BR112015019515A8 (enExample)
CA (2) CA3170716A1 (enExample)
DK (1) DK2956176T3 (enExample)
ES (2) ES2680599T3 (enExample)
IL (2) IL240338B (enExample)
MX (2) MX368155B (enExample)
NZ (1) NZ631119A (enExample)
RU (2) RU2018121529A (enExample)
WO (1) WO2014127268A2 (enExample)
ZA (1) ZA201505628B (enExample)

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AU2014284152B2 (en) * 2013-06-21 2020-01-23 Ionis Pharmaceuticals, Inc. Compositions and methods for modulation of target nucleic acids
HK1248522A1 (zh) * 2015-02-27 2018-10-19 Ionis Pharmaceuticals, Inc. 调节脂肪代谢障碍群体中的载脂蛋白c-iii(apociii)表达
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JP2020517242A (ja) 2017-04-21 2020-06-18 スターテン・バイオテクノロジー・ベー・フェー 抗ＡｐｏＣ３抗体およびその使用方法
WO2018223056A1 (en) 2017-06-02 2018-12-06 Wave Life Sciences Ltd. Oligonucleotide compositions and methods of use thereof
BR112020008514A2 (pt) 2017-10-31 2020-10-20 Staten Biotechnology B.V. anticorpos anti-apoc3 e métodos de uso dos mesmos
US10538583B2 (en) 2017-10-31 2020-01-21 Staten Biotechnology B.V. Anti-APOC3 antibodies and compositions thereof
CA3098624A1 (en) 2018-05-11 2019-11-14 Wave Life Sciences Ltd. Oligonucleotide compositions and methods of use thereof
US20240033280A1 (en) * 2020-10-02 2024-02-01 Ionis Pharmaceuticals, Inc. Methods for reducing apociii expression
CN116814621B (zh) * 2022-08-05 2025-09-09 厦门甘宝利生物医药有限公司 一种抑制apoc3基因表达的rna抑制剂及其应用
WO2025110984A1 (en) * 2023-11-21 2025-05-30 Hydrogene Therapeutics, Inc. Compositions and methods for treating wilson's disease

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