JP2016508984A5 - - Google Patents
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- JP2016508984A5 JP2016508984A5 JP2015549810A JP2015549810A JP2016508984A5 JP 2016508984 A5 JP2016508984 A5 JP 2016508984A5 JP 2015549810 A JP2015549810 A JP 2015549810A JP 2015549810 A JP2015549810 A JP 2015549810A JP 2016508984 A5 JP2016508984 A5 JP 2016508984A5
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261745508P | 2012-12-21 | 2012-12-21 | |
| US61/745,508 | 2012-12-21 | ||
| US201361827325P | 2013-05-24 | 2013-05-24 | |
| US61/827,325 | 2013-05-24 | ||
| PCT/US2013/077139 WO2014100689A1 (en) | 2012-12-21 | 2013-12-20 | Anti-gdf15 antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019007928A Division JP2019056018A (ja) | 2012-12-21 | 2019-01-21 | 抗gdf15抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016508984A JP2016508984A (ja) | 2016-03-24 |
| JP2016508984A5 true JP2016508984A5 (enExample) | 2017-02-09 |
| JP6758832B2 JP6758832B2 (ja) | 2020-09-30 |
Family
ID=50069279
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015549810A Active JP6758832B2 (ja) | 2012-12-21 | 2013-12-20 | 抗gdf15抗体 |
| JP2019007928A Withdrawn JP2019056018A (ja) | 2012-12-21 | 2019-01-21 | 抗gdf15抗体 |
| JP2021009528A Withdrawn JP2021061864A (ja) | 2012-12-21 | 2021-01-25 | 抗gdf15抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019007928A Withdrawn JP2019056018A (ja) | 2012-12-21 | 2019-01-21 | 抗gdf15抗体 |
| JP2021009528A Withdrawn JP2021061864A (ja) | 2012-12-21 | 2021-01-25 | 抗gdf15抗体 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US9175076B2 (enExample) |
| EP (2) | EP3689370A1 (enExample) |
| JP (3) | JP6758832B2 (enExample) |
| KR (1) | KR102208861B1 (enExample) |
| CN (1) | CN105073133B (enExample) |
| AR (1) | AR094271A1 (enExample) |
| AU (1) | AU2013364133B2 (enExample) |
| CA (1) | CA2896076C (enExample) |
| DK (1) | DK2934584T3 (enExample) |
| EA (1) | EA038645B1 (enExample) |
| ES (1) | ES2791183T3 (enExample) |
| MX (1) | MX370720B (enExample) |
| WO (1) | WO2014100689A1 (enExample) |
Families Citing this family (75)
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|---|---|---|---|---|
| DK2006381T3 (en) | 2006-03-31 | 2016-02-22 | Chugai Pharmaceutical Co Ltd | PROCEDURE FOR REGULATING ANTIBODIES BLOOD PHARMACOKINETICS |
| DK2202245T3 (en) | 2007-09-26 | 2016-11-21 | Chugai Pharmaceutical Co Ltd | A method of modifying an antibody isoelectric point VIA amino acid substitution in CDR |
| PT2708559T (pt) | 2008-04-11 | 2018-05-16 | Chugai Pharmaceutical Co Ltd | Molécula de ligação ao antigénio capaz de se ligar repetidamente a duas ou mais moléculas de antigénio |
| MX365235B (es) | 2010-11-30 | 2019-05-28 | Chugai Pharmaceutical Co Ltd | Molécula de unión a antígeno capaz de unir repetidamente a la pluralidad de moléculas de antígeno. |
| MX343729B (es) | 2011-04-08 | 2016-11-18 | Amgen Inc | Factor de diferenciación de crecimiento 15 (gdf-15) y composiciones del mismo para usarse en el tratamiento o mejoramiento de trastornos metabólicos. |
| MX2014009129A (es) | 2012-01-26 | 2014-11-21 | Amgen Inc | Polipeptidos de factor 15 de diferenciacion de crecimiento (gdf-15). |
| EP2830646B1 (en) | 2012-03-27 | 2018-03-07 | NGM Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
| WO2014030750A1 (ja) | 2012-08-24 | 2014-02-27 | 中外製薬株式会社 | マウスFcγRII特異的Fc抗体 |
| TWI855488B (zh) | 2012-08-24 | 2024-09-11 | 日商中外製藥股份有限公司 | FcγRIIb特異性Fc區域變異體 |
| EP3590537A1 (en) | 2012-09-26 | 2020-01-08 | Julius-Maximilians-Universität Würzburg | Monoclonal antibodies to growth and differentiation factor 15 (gdf-15) |
| WO2014100689A1 (en) * | 2012-12-21 | 2014-06-26 | Aveo Pharmaceuticals, Inc. | Anti-gdf15 antibodies |
| US9161966B2 (en) | 2013-01-30 | 2015-10-20 | Ngm Biopharmaceuticals, Inc. | GDF15 mutein polypeptides |
| US9828415B2 (en) | 2013-01-30 | 2017-11-28 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
| SG11201508170TA (en) | 2013-04-02 | 2015-11-27 | Chugai Pharmaceutical Co Ltd | Fc REGION VARIANT |
| US9862752B2 (en) | 2013-07-31 | 2018-01-09 | Amgen Inc. | Growth differentiation factor 15 (GDF-15) constructs |
| EP3063543B1 (en) * | 2013-10-31 | 2020-03-11 | Regeneron Pharmaceuticals, Inc. | Competitive ligand binding assay for detecting neutralizing antibodies |
| EP4005585B1 (en) | 2013-11-21 | 2024-03-27 | The Brigham & Women's Hospital, Inc. | Compositions and methods for treating right ventricular hypertrophy |
| WO2015143126A1 (en) | 2014-03-19 | 2015-09-24 | Mackay Memorial Hospital Of Taiwan Presbyterian Church And Mackay Memorial Social Work Foundation | Immunogenic glycopeptides, composition comprising the glycopeptides and use thereof |
| GB2524553C (en) * | 2014-03-26 | 2017-07-19 | Julius-Maximilians-Universitãt Würzburg | Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and uses thereof for treating cancer cachexia |
| DK3122775T3 (da) | 2014-03-26 | 2020-02-03 | Univ Wuerzburg J Maximilians | Monoklonale antistoffer til vækst- og differentieringsfaktor 15 (gdf-15), og anvendelser deraf til behandling af cancer kakeksi og cancer |
| GB2524552B (en) * | 2014-03-26 | 2017-07-12 | Julius-Maximilians-Universitãt Wurzburg | Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and use thereof for treating cancer |
| EP3157952B1 (en) * | 2014-06-20 | 2021-12-22 | Aveo Pharmaceuticals, Inc. | Treatment of congestive heart failure and other cardiac dysfunction using a gdf15 modulator |
| EP3157953B1 (en) | 2014-06-20 | 2021-12-22 | Aveo Pharmaceuticals, Inc. | Treatment of chronic kidney disease and other renal dysfunction using a gdf15 modulator |
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| EP3197493B1 (en) | 2014-09-25 | 2021-03-10 | Aveo Pharmaceuticals Inc. | Methods of reversing cachexia and prolonging survival comprising administering a gdf15 modulator and an anti-cancer agent |
| KR20170066515A (ko) * | 2014-09-30 | 2017-06-14 | 우니베르지타이트 겐트 | 관절 질환의 치료 방법 |
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| ES2799503T3 (es) | 2014-10-31 | 2020-12-18 | Ngm Biopharmaceuticals Inc | Composiciones y procedimientos de uso para el tratamiento de trastornos metabólicos |
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| CN106349388B (zh) * | 2015-07-17 | 2021-04-02 | 上海佳文英莉生物技术有限公司 | 一种促细胞程序性坏死抗体及其应用 |
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| JP7138567B2 (ja) * | 2016-04-27 | 2022-09-16 | ノバルティス アーゲー | 成長分化因子15に対する抗体およびそれらの使用 |
| US10336812B2 (en) * | 2016-05-10 | 2019-07-02 | Janssen Biotech, Inc. | GDF15 fusion proteins and uses thereof |
| NL2017267B1 (en) * | 2016-07-29 | 2018-02-01 | Aduro Biotech Holdings Europe B V | Anti-pd-1 antibodies |
| US11773162B2 (en) * | 2016-08-05 | 2023-10-03 | Allakos, Inc. | Anti-Siglec-7 antibodies for the treatment of cancer |
| KR102538749B1 (ko) | 2016-08-05 | 2023-06-01 | 추가이 세이야쿠 가부시키가이샤 | Il-8 관련 질환의 치료용 또는 예방용 조성물 |
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| TWI724392B (zh) * | 2018-04-06 | 2021-04-11 | 美商美國禮來大藥廠 | 生長分化因子15促效劑化合物及其使用方法 |
| KR20200140878A (ko) | 2018-04-09 | 2020-12-16 | 암젠 인크 | 성장 분화 인자 15 융합 단백질 |
| US20210340263A1 (en) * | 2018-08-09 | 2021-11-04 | The Wistar Institute | Anti-Follicule Stimulating Hormone Receptor Antibodies |
| KR102715542B1 (ko) * | 2018-08-20 | 2024-10-08 | 화이자 인코포레이티드 | 항-gdf15 항체, 조성물 및 사용 방법 |
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| WO2021066751A1 (en) * | 2019-10-02 | 2021-04-08 | Aslan Pharmaceuticals Pte. Ltd. | Antigen specific binding domains and antibody molecules |
| WO2021111636A1 (ja) * | 2019-12-06 | 2021-06-10 | 大塚製薬株式会社 | 抗gdf15抗体 |
| CN111393526B (zh) * | 2020-03-30 | 2022-04-12 | 中国人民解放军第四军医大学 | 抗gdf15中和性单克隆抗体及其应用 |
| EP4163300A4 (en) * | 2020-06-04 | 2024-07-03 | Daegu Gyeongbuk Institute Of Science and Technology | Gfral-antagonistic antibody and use thereof |
| JPWO2022092326A1 (enExample) * | 2020-10-30 | 2022-05-05 | ||
| WO2022189936A1 (en) * | 2021-03-08 | 2022-09-15 | Medimmune, Llc | Antibodies directed against gdf-15 |
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| WO2023141815A1 (zh) * | 2022-01-26 | 2023-08-03 | 康源博创生物科技(北京)有限公司 | 抗生长分化因子15的抗体分子及其应用 |
| WO2023217068A1 (zh) | 2022-05-09 | 2023-11-16 | 舒泰神(北京)生物制药股份有限公司 | 特异性识别gdf15的抗体及其应用 |
| CN116041497A (zh) * | 2022-12-22 | 2023-05-02 | 杭州贤至生物科技有限公司 | 一种猫杯状病毒(fcv)重组蛋白单克隆抗体及制备方法 |
| CN116444667B (zh) * | 2023-06-13 | 2023-09-01 | 上海驯鹿生物技术有限公司 | 一种靶向gdf15的全人源抗体及其应用 |
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| EP3157953B1 (en) | 2014-06-20 | 2021-12-22 | Aveo Pharmaceuticals, Inc. | Treatment of chronic kidney disease and other renal dysfunction using a gdf15 modulator |
-
2013
- 2013-12-20 WO PCT/US2013/077139 patent/WO2014100689A1/en not_active Ceased
- 2013-12-20 AU AU2013364133A patent/AU2013364133B2/en active Active
- 2013-12-20 CA CA2896076A patent/CA2896076C/en active Active
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