JP2016502843A5 - - Google Patents
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- Publication number
- JP2016502843A5 JP2016502843A5 JP2015547559A JP2015547559A JP2016502843A5 JP 2016502843 A5 JP2016502843 A5 JP 2016502843A5 JP 2015547559 A JP2015547559 A JP 2015547559A JP 2015547559 A JP2015547559 A JP 2015547559A JP 2016502843 A5 JP2016502843 A5 JP 2016502843A5
- Authority
- JP
- Japan
- Prior art keywords
- bioactive agent
- capture
- cell
- solid surface
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012867 bioactive agent Substances 0.000 claims description 17
- 102000004169 proteins and genes Human genes 0.000 claims description 17
- 108090000623 proteins and genes Proteins 0.000 claims description 17
- 239000003446 ligand Substances 0.000 claims description 15
- 239000007787 solid Substances 0.000 claims description 12
- 230000001413 cellular effect Effects 0.000 claims description 9
- 230000004927 fusion Effects 0.000 claims description 5
- 230000003993 interaction Effects 0.000 claims description 4
- 230000005291 magnetic effect Effects 0.000 claims description 3
- 239000011324 bead Substances 0.000 claims description 2
- 229920005989 resin Polymers 0.000 claims description 2
- 239000011347 resin Substances 0.000 claims description 2
- 150000003384 small molecules Chemical group 0.000 claims description 2
- 239000013592 cell lysate Substances 0.000 claims 3
- 230000003834 intracellular effect Effects 0.000 claims 1
- 230000002934 lysing effect Effects 0.000 claims 1
- 230000005298 paramagnetic effect Effects 0.000 claims 1
- 102000006830 Luminescent Proteins Human genes 0.000 description 1
- 108010047357 Luminescent Proteins Proteins 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000710 homodimer Substances 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261736426P | 2012-12-12 | 2012-12-12 | |
| US61/736,426 | 2012-12-12 | ||
| US201361788313P | 2013-03-15 | 2013-03-15 | |
| US61/788,313 | 2013-03-15 | ||
| PCT/US2013/074756 WO2014093671A1 (en) | 2012-12-12 | 2013-12-12 | Compositions and methods for capture of cellular targets of bioactive agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019025449A Division JP6999589B2 (ja) | 2012-12-12 | 2019-02-15 | 生物活性剤の細胞標的の捕捉のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016502843A JP2016502843A (ja) | 2016-02-01 |
| JP2016502843A5 true JP2016502843A5 (enExample) | 2019-02-07 |
| JP6484178B2 JP6484178B2 (ja) | 2019-03-13 |
Family
ID=50934961
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015547559A Active JP6484178B2 (ja) | 2012-12-12 | 2013-12-12 | 生物活性剤の細胞標的の捕捉のための組成物および方法 |
| JP2019025449A Active JP6999589B2 (ja) | 2012-12-12 | 2019-02-15 | 生物活性剤の細胞標的の捕捉のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019025449A Active JP6999589B2 (ja) | 2012-12-12 | 2019-02-15 | 生物活性剤の細胞標的の捕捉のための組成物および方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9551705B2 (enExample) |
| EP (1) | EP2931305B1 (enExample) |
| JP (2) | JP6484178B2 (enExample) |
| KR (2) | KR102272233B1 (enExample) |
| CN (1) | CN104853767B (enExample) |
| AU (2) | AU2013359160B2 (enExample) |
| BR (1) | BR112015013715A2 (enExample) |
| CA (1) | CA2894432C (enExample) |
| IL (1) | IL239213B (enExample) |
| SG (1) | SG11201504520XA (enExample) |
| WO (1) | WO2014093671A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4159833A3 (en) | 2009-12-09 | 2023-07-26 | The Procter & Gamble Company | Fabric and home care products |
| JP6522339B2 (ja) * | 2011-11-21 | 2019-05-29 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | カルボキシｘローダミン類似体 |
| WO2014093671A1 (en) | 2012-12-12 | 2014-06-19 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| JP6604938B2 (ja) | 2013-03-15 | 2019-11-13 | プロメガ コーポレイション | タンパク質を官能基または固体表面に共有結合的に係留するための基質 |
| US10168323B2 (en) | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| WO2016196956A1 (en) * | 2015-06-05 | 2016-12-08 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
| US10458988B2 (en) * | 2017-03-03 | 2019-10-29 | Musc Foundation For Research Development | Biotinylated luminescent probe |
| US12181452B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US12180581B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11709155B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
| US11913944B2 (en) | 2019-03-20 | 2024-02-27 | Promega Corporation | Photoaffinity probes |
| US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
| CN116391122A (zh) | 2020-09-24 | 2023-07-04 | 沃特世科技公司 | 用于反应性分子分离的色谱硬件改进 |
| JP2022182394A (ja) * | 2021-05-28 | 2022-12-08 | 独立行政法人国立病院機構 | 抗原固相化デバイス |
| US20250120928A1 (en) * | 2021-07-14 | 2025-04-17 | University Of Maryland, Baltimore | Suberoylanilide hydroxamic acid (saha) drugs, conjugates, and nanoparticles, and methods of use thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5914095A (en) | 1989-04-07 | 1999-06-22 | Salutar, Inc. | Polychelants containg amide bonds |
| ES2136103T3 (es) | 1992-06-22 | 1999-11-16 | Kyowa Hakko Kogyo Kk | Procedimiento para la preparacion de derivados de estaurosporina. |
| US5756688A (en) | 1992-10-14 | 1998-05-26 | Sterling Winthrop Inc. | MR imaging compositions and methods |
| HK1001498A1 (en) | 1992-10-14 | 1998-06-19 | Nycomed Imaging As | Chelating polymers |
| GB9503969D0 (en) | 1995-02-28 | 1995-04-19 | Sams Bernard | Incrementing mechanism |
| WO2001053355A1 (en) * | 2000-01-24 | 2001-07-26 | The Trustees Of Columbia University In The City Of New York | An in vivo screen using chemical inducers of dimerization |
| US20020168737A1 (en) | 2001-01-24 | 2002-11-14 | Cornish Virginia W. | Binding and catalysis screen for high throughput determination of protein function using chemical inducers of dimerization |
| DK1545613T3 (da) | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| AU2004211584B2 (en) | 2003-01-31 | 2009-11-12 | Promega Corporation | Covalent tethering of functional groups to proteins |
| US7429472B2 (en) | 2003-01-31 | 2008-09-30 | Promega Corporation | Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule |
| KR100507796B1 (ko) | 2003-04-03 | 2005-08-17 | 한미약품 주식회사 | 생체내 반감기가 증가된 ｐｅｇ-생리활성 폴리펩티드 동종이량체 결합체 및 이의 제조방법 |
| US7425436B2 (en) | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
| EP1989548A2 (en) | 2006-02-08 | 2008-11-12 | Promega Corporation | Compositions and methods for capturing and analyzing cross-linked biomolecules |
| JP5420198B2 (ja) * | 2008-06-16 | 2014-02-19 | オリンパス株式会社 | タンパク質相互作用解析方法、ポリヌクレオチド、および、組成物 |
| KR100891456B1 (ko) | 2008-11-06 | 2009-04-01 | 씨지케이 주식회사 | 생리활성물질에 대한 세포내 표적물질을 검출하는 방법 및 장치 |
| PL2456864T3 (pl) * | 2009-05-01 | 2016-04-29 | Promega Corp | Syntetyczna lucyferaza z oplophorus o wzmocnionej emisji światła |
| US8669103B2 (en) | 2010-11-02 | 2014-03-11 | Promega Corporation | Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use |
| WO2014093671A1 (en) | 2012-12-12 | 2014-06-19 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| JP6604938B2 (ja) * | 2013-03-15 | 2019-11-13 | プロメガ コーポレイション | タンパク質を官能基または固体表面に共有結合的に係留するための基質 |
| US10168323B2 (en) * | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| WO2016196956A1 (en) * | 2015-06-05 | 2016-12-08 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
-
2013
- 2013-12-12 WO PCT/US2013/074756 patent/WO2014093671A1/en not_active Ceased
- 2013-12-12 CN CN201380064237.XA patent/CN104853767B/zh active Active
- 2013-12-12 KR KR1020207024366A patent/KR102272233B1/ko active Active
- 2013-12-12 CA CA2894432A patent/CA2894432C/en active Active
- 2013-12-12 SG SG11201504520XA patent/SG11201504520XA/en unknown
- 2013-12-12 AU AU2013359160A patent/AU2013359160B2/en active Active
- 2013-12-12 JP JP2015547559A patent/JP6484178B2/ja active Active
- 2013-12-12 KR KR1020157018280A patent/KR102227321B1/ko active Active
- 2013-12-12 US US14/104,814 patent/US9551705B2/en active Active
- 2013-12-12 EP EP13862430.9A patent/EP2931305B1/en active Active
- 2013-12-12 BR BR112015013715A patent/BR112015013715A2/pt not_active Application Discontinuation
-
2015
- 2015-06-04 IL IL239213A patent/IL239213B/en active IP Right Grant
-
2017
- 2017-01-10 US US15/402,879 patent/US10976312B2/en active Active
-
2019
- 2019-02-14 AU AU2019201035A patent/AU2019201035B9/en active Active
- 2019-02-15 JP JP2019025449A patent/JP6999589B2/ja active Active
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