BR112015013715A2 - sistema, método para capturar o alvo celular, lisado celular e ligante de captura. - Google Patents
sistema, método para capturar o alvo celular, lisado celular e ligante de captura.Info
- Publication number
- BR112015013715A2 BR112015013715A2 BR112015013715A BR112015013715A BR112015013715A2 BR 112015013715 A2 BR112015013715 A2 BR 112015013715A2 BR 112015013715 A BR112015013715 A BR 112015013715A BR 112015013715 A BR112015013715 A BR 112015013715A BR 112015013715 A2 BR112015013715 A2 BR 112015013715A2
- Authority
- BR
- Brazil
- Prior art keywords
- cell
- capture ligand
- capturing
- target
- cell lysate
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261736426P | 2012-12-12 | 2012-12-12 | |
US201361788313P | 2013-03-15 | 2013-03-15 | |
PCT/US2013/074756 WO2014093671A1 (en) | 2012-12-12 | 2013-12-12 | Compositions and methods for capture of cellular targets of bioactive agents |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015013715A2 true BR112015013715A2 (pt) | 2017-09-26 |
Family
ID=50934961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015013715A BR112015013715A2 (pt) | 2012-12-12 | 2013-12-12 | sistema, método para capturar o alvo celular, lisado celular e ligante de captura. |
Country Status (11)
Country | Link |
---|---|
US (2) | US9551705B2 (pt) |
EP (1) | EP2931305B1 (pt) |
JP (2) | JP6484178B2 (pt) |
KR (2) | KR102227321B1 (pt) |
CN (1) | CN104853767B (pt) |
AU (2) | AU2013359160B2 (pt) |
BR (1) | BR112015013715A2 (pt) |
CA (1) | CA2894432C (pt) |
IL (1) | IL239213B (pt) |
SG (1) | SG11201504520XA (pt) |
WO (1) | WO2014093671A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6522339B2 (ja) | 2011-11-21 | 2019-05-29 | プロメガ コーポレイションPromega Corporation | カルボキシxローダミン類似体 |
WO2014093671A1 (en) | 2012-12-12 | 2014-06-19 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
JP6604938B2 (ja) | 2013-03-15 | 2019-11-13 | プロメガ コーポレイション | タンパク質を官能基または固体表面に共有結合的に係留するための基質 |
US10168323B2 (en) | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
WO2016196956A1 (en) | 2015-06-05 | 2016-12-08 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
US10458988B2 (en) * | 2017-03-03 | 2019-10-29 | Musc Foundation For Research Development | Biotinylated luminescent probe |
US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
US11709155B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
EP3941195A4 (en) | 2019-03-20 | 2023-03-22 | Promega Corporation | PHOTOAFFINITY PROBES |
US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
JP2022182394A (ja) * | 2021-05-28 | 2022-12-08 | 独立行政法人国立病院機構 | 抗原固相化デバイス |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5914095A (en) | 1989-04-07 | 1999-06-22 | Salutar, Inc. | Polychelants containg amide bonds |
US5344926A (en) | 1992-06-22 | 1994-09-06 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing staurosporine derivatives |
KR950703582A (ko) | 1992-10-14 | 1995-09-20 | 조이스 이. 마임스 | 킬레이트화 중합체(chelating polymers) |
US5756688A (en) | 1992-10-14 | 1998-05-26 | Sterling Winthrop Inc. | MR imaging compositions and methods |
GB9503969D0 (en) | 1995-02-28 | 1995-04-19 | Sams Bernard | Incrementing mechanism |
US20020004202A1 (en) | 2000-01-24 | 2002-01-10 | Cornish Virginia W. | In vivo screen using chemical inducers of dimerization |
US20020168737A1 (en) * | 2001-01-24 | 2002-11-14 | Cornish Virginia W. | Binding and catalysis screen for high throughput determination of protein function using chemical inducers of dimerization |
HUE027549T2 (hu) * | 2002-07-31 | 2016-10-28 | Seattle Genetics Inc | Hatóanyagot tartalmazó konjugátumok és alkalmazásuk rák, autoimmun betegség vagy fertõzéses betegség kezelésére |
US7429472B2 (en) | 2003-01-31 | 2008-09-30 | Promega Corporation | Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule |
KR20050109934A (ko) | 2003-01-31 | 2005-11-22 | 프로메가 코포레이션 | 관능기의 단백질로의 공유 테더링 |
KR100507796B1 (ko) * | 2003-04-03 | 2005-08-17 | 한미약품 주식회사 | 생체내 반감기가 증가된 peg-생리활성 폴리펩티드 동종이량체 결합체 및 이의 제조방법 |
US7425436B2 (en) | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
EP1989548A2 (en) * | 2006-02-08 | 2008-11-12 | Promega Corporation | Compositions and methods for capturing and analyzing cross-linked biomolecules |
JP5420198B2 (ja) * | 2008-06-16 | 2014-02-19 | オリンパス株式会社 | タンパク質相互作用解析方法、ポリヌクレオチド、および、組成物 |
KR100891456B1 (ko) * | 2008-11-06 | 2009-04-01 | 씨지케이 주식회사 | 생리활성물질에 대한 세포내 표적물질을 검출하는 방법 및 장치 |
EP3409764B1 (en) * | 2009-05-01 | 2020-04-15 | Promega Corporation | Synthetic oplophorus luciferases with enhanced light output |
JP5889910B2 (ja) | 2010-11-02 | 2016-03-22 | プロメガ コーポレイションPromega Corporation | 新規セレンテラジン基質及び使用法 |
WO2014093671A1 (en) | 2012-12-12 | 2014-06-19 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
US10168323B2 (en) * | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
JP6604938B2 (ja) * | 2013-03-15 | 2019-11-13 | プロメガ コーポレイション | タンパク質を官能基または固体表面に共有結合的に係留するための基質 |
WO2016196956A1 (en) * | 2015-06-05 | 2016-12-08 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
-
2013
- 2013-12-12 WO PCT/US2013/074756 patent/WO2014093671A1/en active Application Filing
- 2013-12-12 BR BR112015013715A patent/BR112015013715A2/pt not_active Application Discontinuation
- 2013-12-12 KR KR1020157018280A patent/KR102227321B1/ko active IP Right Grant
- 2013-12-12 SG SG11201504520XA patent/SG11201504520XA/en unknown
- 2013-12-12 US US14/104,814 patent/US9551705B2/en active Active
- 2013-12-12 AU AU2013359160A patent/AU2013359160B2/en active Active
- 2013-12-12 CA CA2894432A patent/CA2894432C/en active Active
- 2013-12-12 KR KR1020207024366A patent/KR102272233B1/ko active IP Right Grant
- 2013-12-12 CN CN201380064237.XA patent/CN104853767B/zh active Active
- 2013-12-12 EP EP13862430.9A patent/EP2931305B1/en active Active
- 2013-12-12 JP JP2015547559A patent/JP6484178B2/ja active Active
-
2015
- 2015-06-04 IL IL239213A patent/IL239213B/en active IP Right Grant
-
2017
- 2017-01-10 US US15/402,879 patent/US10976312B2/en active Active
-
2019
- 2019-02-14 AU AU2019201035A patent/AU2019201035B9/en active Active
- 2019-02-15 JP JP2019025449A patent/JP6999589B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
US9551705B2 (en) | 2017-01-24 |
AU2019201035B9 (en) | 2021-02-11 |
KR20150093222A (ko) | 2015-08-17 |
SG11201504520XA (en) | 2015-07-30 |
AU2013359160B2 (en) | 2018-11-15 |
AU2019201035A1 (en) | 2019-03-07 |
JP2019092517A (ja) | 2019-06-20 |
CN104853767A (zh) | 2015-08-19 |
AU2013359160A2 (en) | 2015-11-12 |
EP2931305A4 (en) | 2016-08-17 |
CA2894432C (en) | 2022-06-07 |
WO2014093671A1 (en) | 2014-06-19 |
KR102272233B1 (ko) | 2021-07-01 |
KR20200103867A (ko) | 2020-09-02 |
AU2019201035B2 (en) | 2020-09-03 |
US10976312B2 (en) | 2021-04-13 |
EP2931305A1 (en) | 2015-10-21 |
JP2016502843A (ja) | 2016-02-01 |
CA2894432A1 (en) | 2014-06-19 |
JP6999589B2 (ja) | 2022-02-04 |
US20170115283A1 (en) | 2017-04-27 |
US20140199712A1 (en) | 2014-07-17 |
EP2931305B1 (en) | 2018-11-28 |
IL239213B (en) | 2020-03-31 |
AU2013359160A1 (en) | 2015-07-09 |
CN104853767B (zh) | 2017-04-05 |
JP6484178B2 (ja) | 2019-03-13 |
IL239213A0 (en) | 2015-07-30 |
KR102227321B1 (ko) | 2021-03-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112015013715A2 (pt) | sistema, método para capturar o alvo celular, lisado celular e ligante de captura. | |
BR112014027610A2 (pt) | sistema de detecção e método. | |
BR112015002349A2 (pt) | sistema de filtragem, e, método de filtração | |
BR112015009932A2 (pt) | método e sistema. | |
BR112013025752A2 (pt) | método e sistema para autenticar entidades por intermédio de terminais. | |
BR112013030520A2 (pt) | método, sistema, e, composição. | |
BRPI1106068A2 (pt) | dispositivo de recepção, e, sistema de cãmera. | |
BR112013015581A2 (pt) | método, e. sistema | |
BR112015029662A2 (pt) | sistema, e método | |
BR112015005096A2 (pt) | dispositivo, método, e sistema de suprimento de conteúdo, e, programa. | |
BR112015014394A2 (pt) | Conjunto de barbear substituível, sistema de barbear e método de barbear. | |
BR112015000671A2 (pt) | sistema de biorrefinaria, métodos e composições dos mesmos. | |
EP2888349A4 (en) | SYSTEM, DEVICE AND METHOD FOR MULTIPLEX DETECTION WITH HIGH THROUGHPUT | |
BR112016009373A2 (pt) | Sistema, e, método de detecção de descarga parcial | |
BR112014032113A2 (pt) | sistema de conversão de biomassa, e, método. | |
BR112014026864A2 (pt) | sistema, e método | |
BR112014026800A2 (pt) | método e sistema para extração de brotos e uso do sistema. | |
BR112012028663A2 (pt) | método, e, sistema | |
BR112014026818A2 (pt) | método, produto e sistema. | |
BR112014018562A2 (pt) | sistema e método de processamento de imagem de vestuário, e meio legível por computador | |
BR112014032114A2 (pt) | sistema de conversão de biomassa, e, método. | |
BR112015013155A2 (pt) | método, e sistema | |
BR112015000976A2 (pt) | sistema e método para monitoramento de respiração. | |
BR112015023685A2 (pt) | sistema, e método. | |
BR112013030399A2 (pt) | sistema, dispositivo e método de formação de imagem |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |