JP2015506699A5 - - Google Patents
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- JP2015506699A5 JP2015506699A5 JP2014555774A JP2014555774A JP2015506699A5 JP 2015506699 A5 JP2015506699 A5 JP 2015506699A5 JP 2014555774 A JP2014555774 A JP 2014555774A JP 2014555774 A JP2014555774 A JP 2014555774A JP 2015506699 A5 JP2015506699 A5 JP 2015506699A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- nucleic acid
- polypeptide
- item
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261594149P | 2012-02-02 | 2012-02-02 | |
| US61/594,149 | 2012-02-02 | ||
| PCT/US2013/024406 WO2013116698A2 (en) | 2012-02-02 | 2013-02-01 | High throughput screen for biologically active polypeptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015506699A JP2015506699A (ja) | 2015-03-05 |
| JP2015506699A5 true JP2015506699A5 (enExample) | 2016-03-10 |
| JP6196241B2 JP6196241B2 (ja) | 2017-09-13 |
Family
ID=47750048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014555774A Expired - Fee Related JP6196241B2 (ja) | 2012-02-02 | 2013-02-01 | 生物学的に活性なポリペプチドのハイスループットスクリーニング |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9701959B2 (enExample) |
| EP (1) | EP2809783A2 (enExample) |
| JP (1) | JP6196241B2 (enExample) |
| CA (1) | CA2861387A1 (enExample) |
| WO (1) | WO2013116698A2 (enExample) |
Families Citing this family (40)
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|---|---|---|---|---|
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
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| EP2530168B1 (en) | 2006-05-11 | 2015-09-16 | Raindance Technologies, Inc. | Microfluidic Devices |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| WO2010009365A1 (en) | 2008-07-18 | 2010-01-21 | Raindance Technologies, Inc. | Droplet libraries |
| US8528589B2 (en) | 2009-03-23 | 2013-09-10 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| JP5934657B2 (ja) | 2010-02-12 | 2016-06-15 | レインダンス テクノロジーズ， インコーポレイテッド | デジタル検体分析 |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| WO2012045012A2 (en) | 2010-09-30 | 2012-04-05 | Raindance Technologies, Inc. | Sandwich assays in droplets |
| EP3859011A1 (en) | 2011-02-11 | 2021-08-04 | Bio-Rad Laboratories, Inc. | Methods for forming mixed droplets |
| EP2675819B1 (en) | 2011-02-18 | 2020-04-08 | Bio-Rad Laboratories, Inc. | Compositions and methods for molecular labeling |
| DE202012013668U1 (de) | 2011-06-02 | 2019-04-18 | Raindance Technologies, Inc. | Enzymquantifizierung |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| EP3305918B1 (en) | 2012-03-05 | 2020-06-03 | President and Fellows of Harvard College | Methods for epigenetic sequencing |
| US9290552B2 (en) | 2012-12-21 | 2016-03-22 | Dna Twopointo, Inc. | Fluorescent and colored proteins and methods for using them |
| US8975042B2 (en) * | 2012-12-21 | 2015-03-10 | Dna Twopointo, Inc. | Fluorescent and colored proteins and methods for using them |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| LT3134536T (lt) | 2014-04-21 | 2020-05-11 | President And Fellows Of Harvard College | Sistemos ir būdai, skirti nukleorūgščių brūkšniniam kodavimui |
| CN107614700B (zh) * | 2015-03-11 | 2026-03-31 | 布罗德研究所有限公司 | 基因型和表型偶联 |
| EP3283629A4 (en) | 2015-04-17 | 2018-08-29 | President and Fellows of Harvard College | Barcoding systems and methods for gene sequencing and other applications |
| WO2016187466A1 (en) * | 2015-05-20 | 2016-11-24 | Invenra, Inc. | Methods, apparatus and compositions for expression and high throughput screening |
| WO2017004250A1 (en) | 2015-06-29 | 2017-01-05 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University | Systems and methods for continuous flow digital droplet polymerase chain reaction bioanalysis |
| EP3397764A4 (en) | 2015-12-30 | 2019-05-22 | Bio-Rad Laboratories, Inc. | DIGITAL PROTEIN QUANTIFICATION |
| ES2996699T3 (en) * | 2016-04-12 | 2025-02-13 | Medimmune Llc | Immune repertoire mining |
| KR102657960B1 (ko) * | 2016-10-18 | 2024-04-16 | 삼성전자주식회사 | 힘 전달 프레임 및 이를 포함하는 운동 보조 장치 |
| JP2020500517A (ja) | 2016-11-28 | 2020-01-16 | アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ | 連続流小滴反応に関連するシステムおよび方法 |
| RU2019123063A (ru) | 2016-12-23 | 2021-01-26 | Вистерра, Инк. | Связывающие полипептиды и способы их получения |
| AU2018262331A1 (en) * | 2017-05-05 | 2019-11-21 | Scipio Bioscience | Methods for trapping and barcoding discrete biological units in hydrogel |
| EP4741512A2 (en) | 2017-09-22 | 2026-05-13 | University of Washington | In situ combinatorial labeling of cellular molecules |
| EP3752596A4 (en) * | 2018-02-15 | 2021-12-15 | enEvolv, Inc. | SENSOR SYSTEMS |
| CA3095588A1 (en) | 2018-04-02 | 2019-10-10 | Dropworks, Inc. | Systems and methods for serial flow emulsion processes |
| WO2020193368A1 (en) * | 2019-03-22 | 2020-10-01 | Qiagen Gmbh | Method for improving the amplification efficiency of bead-based emulsion pcr (empcr) |
| WO2020247976A1 (en) * | 2019-06-03 | 2020-12-10 | Dropworks, Inc. | Systems and methods for stabilizing emulsions |
| AU2020361681A1 (en) | 2019-10-10 | 2022-05-05 | 1859, Inc. | Methods and systems for microfluidic screening |
| CA3187408A1 (en) * | 2020-07-28 | 2022-02-03 | Michael Roy GOTRIK | Systems and methods for assaying a plurality of polypeptides |
| WO2022037682A1 (en) * | 2020-08-21 | 2022-02-24 | Hifibio (Shanghai) Limited | Functional screening using droplet-based microfluidics |
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-
2013
- 2013-02-01 US US14/375,943 patent/US9701959B2/en not_active Expired - Fee Related
- 2013-02-01 CA CA2861387A patent/CA2861387A1/en not_active Abandoned
- 2013-02-01 EP EP13706121.4A patent/EP2809783A2/en not_active Withdrawn
- 2013-02-01 JP JP2014555774A patent/JP6196241B2/ja not_active Expired - Fee Related
- 2013-02-01 WO PCT/US2013/024406 patent/WO2013116698A2/en not_active Ceased
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