IL239213B - Preparations and methods for capturing cellular targets of biologically active substances - Google Patents
Preparations and methods for capturing cellular targets of biologically active substancesInfo
- Publication number
- IL239213B IL239213B IL239213A IL23921315A IL239213B IL 239213 B IL239213 B IL 239213B IL 239213 A IL239213 A IL 239213A IL 23921315 A IL23921315 A IL 23921315A IL 239213 B IL239213 B IL 239213B
- Authority
- IL
- Israel
- Prior art keywords
- bioactiv
- capture
- agents
- compositions
- methods
- Prior art date
Links
- 230000001413 cellular effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261736426P | 2012-12-12 | 2012-12-12 | |
| US201361788313P | 2013-03-15 | 2013-03-15 | |
| PCT/US2013/074756 WO2014093671A1 (en) | 2012-12-12 | 2013-12-12 | Compositions and methods for capture of cellular targets of bioactive agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL239213A0 IL239213A0 (en) | 2015-07-30 |
| IL239213B true IL239213B (en) | 2020-03-31 |
Family
ID=50934961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL239213A IL239213B (en) | 2012-12-12 | 2015-06-04 | Preparations and methods for capturing cellular targets of biologically active substances |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9551705B2 (enExample) |
| EP (1) | EP2931305B1 (enExample) |
| JP (2) | JP6484178B2 (enExample) |
| KR (2) | KR102272233B1 (enExample) |
| CN (1) | CN104853767B (enExample) |
| AU (2) | AU2013359160B2 (enExample) |
| BR (1) | BR112015013715A2 (enExample) |
| CA (1) | CA2894432C (enExample) |
| IL (1) | IL239213B (enExample) |
| SG (1) | SG11201504520XA (enExample) |
| WO (1) | WO2014093671A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4159833A3 (en) | 2009-12-09 | 2023-07-26 | The Procter & Gamble Company | Fabric and home care products |
| EP2782916B1 (en) * | 2011-11-21 | 2018-02-28 | Promega Corporation | Carboxy x rhodamine analogs |
| BR112015013715A2 (pt) | 2012-12-12 | 2017-09-26 | Promega Corp | sistema, método para capturar o alvo celular, lisado celular e ligante de captura. |
| US10168323B2 (en) | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| US11072811B2 (en) | 2013-03-15 | 2021-07-27 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
| JP6876002B2 (ja) * | 2015-06-05 | 2021-05-26 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | 機能的要素を共有結合により係留させるための細胞透過性、細胞適合性、かつ開裂可能であるリンカー |
| US10458988B2 (en) * | 2017-03-03 | 2019-10-29 | Musc Foundation For Research Development | Biotinylated luminescent probe |
| US11709155B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US12180581B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
| US12181452B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| WO2020191339A1 (en) | 2019-03-20 | 2020-09-24 | Promega Corporation | Photoaffinity probes |
| US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
| US12352734B2 (en) | 2020-09-24 | 2025-07-08 | Waters Technologies Corporation | Chromatographic hardware improvements for separation of reactive molecules |
| JP2022182394A (ja) * | 2021-05-28 | 2022-12-08 | 独立行政法人国立病院機構 | 抗原固相化デバイス |
| EP4370109A4 (en) * | 2021-07-14 | 2025-10-22 | Univ Maryland | SUBEROYLANILIDE HYDROXAMIC ACID (SAHA) DRUGS, CONJUGATES AND NANOPARTICLES, AND METHODS OF USE THEREOF |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5914095A (en) | 1989-04-07 | 1999-06-22 | Salutar, Inc. | Polychelants containg amide bonds |
| EP0575955B1 (en) | 1992-06-22 | 1999-09-15 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing staurosporine derivatives |
| US5756688A (en) | 1992-10-14 | 1998-05-26 | Sterling Winthrop Inc. | MR imaging compositions and methods |
| WO1994009056A1 (en) | 1992-10-14 | 1994-04-28 | Sterling Winthrop Inc. | Chelating polymers |
| GB9503969D0 (en) | 1995-02-28 | 1995-04-19 | Sams Bernard | Incrementing mechanism |
| US20020004202A1 (en) | 2000-01-24 | 2002-01-10 | Cornish Virginia W. | In vivo screen using chemical inducers of dimerization |
| US20020168737A1 (en) * | 2001-01-24 | 2002-11-14 | Cornish Virginia W. | Binding and catalysis screen for high throughput determination of protein function using chemical inducers of dimerization |
| DK1545613T3 (da) | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| US7429472B2 (en) | 2003-01-31 | 2008-09-30 | Promega Corporation | Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule |
| EP2455457B1 (en) | 2003-01-31 | 2015-03-11 | Promega Corporation | Covalent tethering of functional groups to proteins |
| KR100507796B1 (ko) | 2003-04-03 | 2005-08-17 | 한미약품 주식회사 | 생체내 반감기가 증가된 ｐｅｇ-생리활성 폴리펩티드 동종이량체 결합체 및 이의 제조방법 |
| US7425436B2 (en) | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
| EP1989548A2 (en) * | 2006-02-08 | 2008-11-12 | Promega Corporation | Compositions and methods for capturing and analyzing cross-linked biomolecules |
| JP5420198B2 (ja) * | 2008-06-16 | 2014-02-19 | オリンパス株式会社 | タンパク質相互作用解析方法、ポリヌクレオチド、および、組成物 |
| KR100891456B1 (ko) | 2008-11-06 | 2009-04-01 | 씨지케이 주식회사 | 생리활성물질에 대한 세포내 표적물질을 검출하는 방법 및 장치 |
| WO2010127368A1 (en) | 2009-05-01 | 2010-11-04 | Promega Corporation | Synthetic oplophorus luciferases with enhanced light output |
| SG10202103336SA (en) * | 2010-11-02 | 2021-04-29 | Promega Corp | Novel coelenterazine substrates and methods of use |
| BR112015013715A2 (pt) | 2012-12-12 | 2017-09-26 | Promega Corp | sistema, método para capturar o alvo celular, lisado celular e ligante de captura. |
| US10168323B2 (en) | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| US11072811B2 (en) * | 2013-03-15 | 2021-07-27 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
| JP6876002B2 (ja) * | 2015-06-05 | 2021-05-26 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | 機能的要素を共有結合により係留させるための細胞透過性、細胞適合性、かつ開裂可能であるリンカー |
-
2013
- 2013-12-12 BR BR112015013715A patent/BR112015013715A2/pt not_active Application Discontinuation
- 2013-12-12 CA CA2894432A patent/CA2894432C/en active Active
- 2013-12-12 EP EP13862430.9A patent/EP2931305B1/en active Active
- 2013-12-12 AU AU2013359160A patent/AU2013359160B2/en active Active
- 2013-12-12 CN CN201380064237.XA patent/CN104853767B/zh active Active
- 2013-12-12 JP JP2015547559A patent/JP6484178B2/ja active Active
- 2013-12-12 KR KR1020207024366A patent/KR102272233B1/ko active Active
- 2013-12-12 US US14/104,814 patent/US9551705B2/en active Active
- 2013-12-12 WO PCT/US2013/074756 patent/WO2014093671A1/en not_active Ceased
- 2013-12-12 KR KR1020157018280A patent/KR102227321B1/ko active Active
- 2013-12-12 SG SG11201504520XA patent/SG11201504520XA/en unknown
-
2015
- 2015-06-04 IL IL239213A patent/IL239213B/en active IP Right Grant
-
2017
- 2017-01-10 US US15/402,879 patent/US10976312B2/en active Active
-
2019
- 2019-02-14 AU AU2019201035A patent/AU2019201035B9/en active Active
- 2019-02-15 JP JP2019025449A patent/JP6999589B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10976312B2 (en) | 2021-04-13 |
| KR20200103867A (ko) | 2020-09-02 |
| KR20150093222A (ko) | 2015-08-17 |
| CA2894432A1 (en) | 2014-06-19 |
| IL239213A0 (en) | 2015-07-30 |
| EP2931305A4 (en) | 2016-08-17 |
| AU2019201035B2 (en) | 2020-09-03 |
| AU2019201035A1 (en) | 2019-03-07 |
| KR102272233B1 (ko) | 2021-07-01 |
| US9551705B2 (en) | 2017-01-24 |
| JP2019092517A (ja) | 2019-06-20 |
| JP6999589B2 (ja) | 2022-02-04 |
| AU2019201035B9 (en) | 2021-02-11 |
| AU2013359160B2 (en) | 2018-11-15 |
| EP2931305A1 (en) | 2015-10-21 |
| AU2013359160A1 (en) | 2015-07-09 |
| CN104853767B (zh) | 2017-04-05 |
| EP2931305B1 (en) | 2018-11-28 |
| BR112015013715A2 (pt) | 2017-09-26 |
| JP2016502843A (ja) | 2016-02-01 |
| CA2894432C (en) | 2022-06-07 |
| SG11201504520XA (en) | 2015-07-30 |
| CN104853767A (zh) | 2015-08-19 |
| KR102227321B1 (ko) | 2021-03-12 |
| US20170115283A1 (en) | 2017-04-27 |
| US20140199712A1 (en) | 2014-07-17 |
| JP6484178B2 (ja) | 2019-03-13 |
| WO2014093671A1 (en) | 2014-06-19 |
| AU2013359160A2 (en) | 2015-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |