|
US61945A
(en)
|
|
1867-02-12 |
|
James maeshall |
|
US2229275A
(en)
|
1939-07-15 |
1941-01-21 |
M J B Company |
Key for cans
|
|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
IL47062A
(en)
|
1975-04-10 |
1979-07-25 |
Yeda Res & Dev |
Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde
|
|
FR2413974A1
(fr)
|
1978-01-06 |
1979-08-03 |
David Bernard |
Sechoir pour feuilles imprimees par serigraphie
|
|
US4665077A
(en)
|
1979-03-19 |
1987-05-12 |
The Upjohn Company |
Method for treating rejection of organ or skin grafts with 6-aryl pyrimidine compounds
|
|
WO1981001145A1
(en)
|
1979-10-18 |
1981-04-30 |
Univ Illinois |
Hydrolytic enzyme-activatible pro-drugs
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
US4676980A
(en)
*
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
|
US6893625B1
(en)
*
|
1986-10-27 |
2005-05-17 |
Royalty Pharma Finance Trust |
Chimeric antibody with specificity to human B cell surface antigen
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
GB8705477D0
(en)
|
1987-03-09 |
1987-04-15 |
Carlton Med Prod |
Drug delivery systems
|
|
US4975278A
(en)
|
1988-02-26 |
1990-12-04 |
Bristol-Myers Company |
Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
|
|
US5283187A
(en)
|
1987-11-17 |
1994-02-01 |
Brown University Research Foundation |
Cell culture-containing tubular capsule produced by co-extrusion
|
|
US4892538A
(en)
|
1987-11-17 |
1990-01-09 |
Brown University Research Foundation |
In vivo delivery of neurotransmitters by implanted, encapsulated cells
|
|
WO1989008114A1
(en)
|
1988-02-25 |
1989-09-08 |
The General Hospital Corporation |
Rapid immunoselection cloning method
|
|
US5506126A
(en)
|
1988-02-25 |
1996-04-09 |
The General Hospital Corporation |
Rapid immunoselection cloning method
|
|
IL85746A
(en)
|
1988-03-15 |
1994-05-30 |
Yeda Res & Dev |
Preparations comprising t-lymphocyte cells treated with 8-methoxypsoralen or cell membranes separated therefrom for preventing or treating autoimmune diseases
|
|
US4861579A
(en)
|
1988-03-17 |
1989-08-29 |
American Cyanamid Company |
Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies
|
|
FI891226A7
(fi)
|
1988-04-28 |
1989-10-29 |
The Board Of Trustees Of The Leland |
Anti-T-solun reseptorideterminantit autoimmuunisairauden hoitoon
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
WO1990008187A1
(en)
|
1989-01-19 |
1990-07-26 |
Dana Farber Cancer Institute |
Soluble two domain cd2 protein
|
|
CA2046909A1
(en)
|
1989-03-21 |
1990-09-22 |
Mark D. Howell |
Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
ES2096590T3
(es)
|
1989-06-29 |
1997-03-16 |
Medarex Inc |
Reactivos biespecificos para la terapia del sida.
|
|
DE69031919T3
(de)
|
1989-07-19 |
2005-01-27 |
Connetics Corp., Palo Alto |
T-zell-rezeptor-peptide als heilmittel für autoimmune und bösartige krankheiten
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5208020A
(en)
*
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
|
AU8295491A
(en)
|
1990-06-29 |
1992-01-23 |
Biosource Technologies Incorporated |
Melanin production by transformed microorganisms
|
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
|
JPH06507398A
(ja)
|
1991-05-14 |
1994-08-25 |
リプリジェン コーポレーション |
Ｈｉｖ感染治療のための異種複合抗体
|
|
EP0940468A1
(en)
|
1991-06-14 |
1999-09-08 |
Genentech, Inc. |
Humanized antibody variable domain
|
|
MX9204374A
(es)
|
1991-07-25 |
1993-03-01 |
Idec Pharma Corp |
Anticuerpo recombinante y metodo para su produccion.
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
FI941572L
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
|
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
|
JPH07501451A
(ja)
|
1991-11-25 |
1995-02-16 |
エンゾン・インコーポレイテッド |
多価抗原結合タンパク質
|
|
DE69333807T2
(de)
|
1992-02-06 |
2006-02-02 |
Chiron Corp., Emeryville |
Marker für krebs und biosynthetisches bindeprotein dafür
|
|
JP3571337B2
(ja)
|
1992-02-11 |
2004-09-29 |
セル ジェネシス，インコーポレーテッド |
遺伝子標的現象による同型遺伝子接合
|
|
US5573905A
(en)
|
1992-03-30 |
1996-11-12 |
The Scripps Research Institute |
Encoded combinatorial chemical libraries
|
|
DE69322860T2
(de)
|
1992-04-03 |
1999-07-01 |
Genentech, Inc., South San Francisco, Calif. |
Antikörper gegen alpha v beta 3 integrin
|
|
ZA932522B
(en)
|
1992-04-10 |
1993-12-20 |
Res Dev Foundation |
Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
|
|
CA2134773A1
(en)
|
1992-06-04 |
1993-12-09 |
Robert J. Debs |
Methods and compositions for in vivo gene therapy
|
|
DE69308573T2
(de)
|
1992-08-17 |
1997-08-07 |
Genentech Inc |
Bispezifische immunoadhesine
|
|
US7744877B2
(en)
|
1992-11-13 |
2010-06-29 |
Biogen Idec Inc. |
Expression and use of anti-CD20 Antibodies
|
|
US5648267A
(en)
|
1992-11-13 |
1997-07-15 |
Idec Pharmaceuticals Corporation |
Impaired dominant selectable marker sequence and intronic insertion strategies for enhancement of expression of gene product and expression vector systems comprising same
|
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
EP1005870B1
(en)
|
1992-11-13 |
2009-01-21 |
Biogen Idec Inc. |
Therapeutic application of chimeric antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
DE669986T1
(de)
|
1992-11-13 |
1996-10-10 |
Idec Pharma Corp |
Völlig unfunktionelle konsensus-kozak-sequenzen zur säugetier-exprimierung.
|
|
US5417972A
(en)
|
1993-08-02 |
1995-05-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of killing B-cells in a complement independent and an ADCC independent manner using antibodies which specifically bind CDIM
|
|
US5595721A
(en)
|
1993-09-16 |
1997-01-21 |
Coulter Pharmaceutical, Inc. |
Radioimmunotherapy of lymphoma using anti-CD20
|
|
CA2195557C
(en)
*
|
1994-08-12 |
2006-10-17 |
Shui-On Leung |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
|
US5910486A
(en)
|
1994-09-06 |
1999-06-08 |
Uab Research Foundation |
Methods for modulating protein function in cells using, intracellular antibody homologues
|
|
US6214388B1
(en)
|
1994-11-09 |
2001-04-10 |
The Regents Of The University Of California |
Immunoliposomes that optimize internalization into target cells
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5641870A
(en)
*
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
|
US5739277A
(en)
|
1995-04-14 |
1998-04-14 |
Genentech Inc. |
Altered polypeptides with increased half-life
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
PT1516628E
(pt)
|
1995-07-27 |
2013-09-24 |
Genentech Inc |
Formulação de proteína liofilizada isotónica estável
|
|
GB9603256D0
(en)
|
1996-02-16 |
1996-04-17 |
Wellcome Found |
Antibodies
|
|
US20010056066A1
(en)
|
1996-07-26 |
2001-12-27 |
Smithkline Beecham Corporation |
Method of treating immune cell mediated systemic diseases
|
|
US6024965A
(en)
|
1996-10-18 |
2000-02-15 |
Erasums University Rotterdam |
Induction of REV and TAT specific cytotoxic T-cells for prevention and treatment of human immunodeficiency virus (HIV) infection
|
|
DE69739673D1
(de)
|
1996-11-27 |
2009-12-31 |
Genentech Inc |
Affinitätsreinigung von Polypeptid-Proteinen auf einer Protein A Matrix
|
|
US6183744B1
(en)
|
1997-03-24 |
2001-02-06 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
US6991790B1
(en)
*
|
1997-06-13 |
2006-01-31 |
Genentech, Inc. |
Antibody formulation
|
|
DK0999853T3
(da)
|
1997-06-13 |
2003-04-22 |
Genentech Inc |
Stabiliseret antostofformulering
|
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
|
US20040191256A1
(en)
|
1997-06-24 |
2004-09-30 |
Genentech, Inc. |
Methods and compositions for galactosylated glycoproteins
|
|
ES2244066T3
(es)
|
1997-06-24 |
2005-12-01 |
Genentech, Inc. |
Procedimiento y composiciones de glicoproteinas galactosiladas.
|
|
US6368596B1
(en)
|
1997-07-08 |
2002-04-09 |
Board Of Regents, The University Of Texas System |
Compositions and methods for homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells
|
|
EP1028751B1
(en)
|
1997-10-31 |
2008-12-31 |
Genentech, Inc. |
Methods and compositions comprising glycoprotein glycoforms
|
|
US6528624B1
(en)
*
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
US6242195B1
(en)
|
1998-04-02 |
2001-06-05 |
Genentech, Inc. |
Methods for determining binding of an analyte to a receptor
|
|
DE69937291T2
(de)
|
1998-04-02 |
2008-07-10 |
Genentech, Inc., South San Francisco |
Antikörpervarianten und fragmente davon
|
|
ES2434961T5
(es)
|
1998-04-20 |
2018-01-18 |
Roche Glycart Ag |
Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo
|
|
ES2292682T3
(es)
|
1998-05-06 |
2008-03-16 |
Genentech, Inc. |
Purificacion de anticuerpos mediante cromatografia de intercambio ionico.
|
|
GB9811969D0
(en)
|
1998-06-03 |
1998-07-29 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
KR101023367B1
(ko)
|
1998-08-11 |
2011-03-18 |
바이오겐 아이덱 인크. |
Ｂ-세포 림프종을 치료하기 위한 항-ｃｄ２０ 항체를 포함하는 약제
|
|
GB9821061D0
(en)
|
1998-09-28 |
1998-11-18 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
US6224866B1
(en)
|
1998-10-07 |
2001-05-01 |
Biocrystal Ltd. |
Immunotherapy of B cell involvement in progression of solid, nonlymphoid tumors
|
|
KR20010103655A
(ko)
|
1998-11-09 |
2001-11-23 |
케네쓰 제이. 울코트 |
키메라 항-ｃｄ２０항체를 이용한 순환성 종양세포와관련된 혈액학적 악성종양의 치료법
|
|
BR9915149A
(pt)
|
1998-11-09 |
2001-08-07 |
Idec Pharma Corp |
Tratamento com anticorpo anti-cd20 quimérico de pacientes recebendo transplantes de bmt ou de pbsc
|
|
GB9826174D0
(en)
|
1998-11-30 |
1999-01-20 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9828074D0
(en)
|
1998-12-18 |
1999-02-17 |
Glaxo Group Ltd |
Therapeutically useful compounds
|
|
KR101077001B1
(ko)
|
1999-01-15 |
2011-10-26 |
제넨테크, 인크. |
효과기 기능이 변화된 폴리펩티드 변이체
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US6897044B1
(en)
|
1999-01-28 |
2005-05-24 |
Biogen Idec, Inc. |
Production of tetravalent antibodies
|
|
US6596657B1
(en)
*
|
1999-02-17 |
2003-07-22 |
Poly-Med, Inc. |
Antimicrobial fabrics
|
|
EP1035172A3
(en)
|
1999-03-12 |
2002-11-27 |
Fuji Photo Film Co., Ltd. |
Azomethine compound and oily magenta ink
|
|
EP1176195B1
(en)
|
1999-04-09 |
2013-05-22 |
Kyowa Hakko Kirin Co., Ltd. |
Method for controlling the activity of immunologically functional molecule
|
|
HK1043312B
(en)
|
1999-05-07 |
2006-07-28 |
Genentech, Inc. |
Treatment of autoimmune diseases with antagonists which bind to b cell surface markers
|
|
EP1194167B1
(en)
|
1999-06-09 |
2009-08-19 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target b-cells
|
|
ITMI991299A1
(it)
|
1999-06-11 |
2000-12-11 |
Consiglio Nazionale Ricerche |
Uso di anticorpi contro antigeni di superficie per il trattamento della malattia trapianto contro ospite
|
|
DE19930748C2
(de)
|
1999-07-02 |
2001-05-17 |
Infineon Technologies Ag |
Verfahren zur Herstellung von EEPROM- und DRAM-Grabenspeicherzellbereichen auf einem Chip
|
|
HUP0202238A3
(en)
|
1999-07-12 |
2004-05-28 |
Idec Pharmaceuticals Inc San D |
Blocking immune response to a foreign antigen using an antagonist which binds to cd20
|
|
US6451284B1
(en)
|
1999-08-11 |
2002-09-17 |
Idec Pharmaceuticals Corporation |
Clinical parameters for determining hematologic toxicity prior to radioimmunotheraphy
|
|
CN101259270A
(zh)
|
1999-08-11 |
2008-09-10 |
拜奥根Idec公司 |
用抗cd20抗体治疗累及骨髓的非霍奇金淋巴瘤患者
|
|
US8557244B1
(en)
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
|
WO2001013945A1
(en)
|
1999-08-23 |
2001-03-01 |
Biocrystal Ltd. |
Methods and compositions for immunotherapy of b cell involvement in promotion of a disease condition comprising multiple sclerosis
|
|
US6238302B1
(en)
*
|
1999-09-03 |
2001-05-29 |
Callaway Golf Company |
Golf club head with an insert having integral tabs
|
|
US20030044420A1
(en)
*
|
1999-09-24 |
2003-03-06 |
Mccormick Alison A. |
Self antigen vaccines for treating B cell lymphomas and other cancers
|
|
AU7950400A
(en)
|
1999-10-19 |
2001-04-30 |
Kyowa Hakko Kogyo Co. Ltd. |
Process for producing polypeptide
|
|
US20020006404A1
(en)
|
1999-11-08 |
2002-01-17 |
Idec Pharmaceuticals Corporation |
Treatment of cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
|
|
US20020028178A1
(en)
|
2000-07-12 |
2002-03-07 |
Nabil Hanna |
Treatment of B cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
|
|
WO2001034194A1
(en)
|
1999-11-08 |
2001-05-17 |
Idec Pharmaceuticals Corporation |
Treatment of b cell malignancies using anti-cd40l antibodies in combination with anti-cd20 antibodies and/or chemotherapeutics and radiotherapy
|
|
AU4721901A
(en)
*
|
2000-02-25 |
2001-09-03 |
Immunex Corp |
Integrin antagonists
|
|
AU2001247737A1
(en)
|
2000-03-24 |
2001-10-08 |
Chiron Corporation |
Methods of therapy for non-hodgkin's lymphoma using a combination of an antibodyto cd20 and interleuking-2
|
|
US20030185796A1
(en)
|
2000-03-24 |
2003-10-02 |
Chiron Corporation |
Methods of therapy for non-hodgkin's lymphoma
|
|
KR20020091170A
(ko)
|
2000-03-31 |
2002-12-05 |
아이덱 파마슈티칼즈 코포레이션 |
Ｂ 세포 림프종의 치료를 위한 항-사이토카인 항체 또는길항제 및 항-ｃｄ２０의 조합된 사용
|
|
ES2637801T3
(es)
|
2000-04-11 |
2017-10-17 |
Genentech, Inc. |
Anticuerpos multivalentes y usos de los mismos
|
|
DE60130910T2
(de)
|
2000-04-17 |
2008-07-10 |
Ucb Pharma, S.A. |
Enamin-derivate als zell-adhäsionsmoleküle
|
|
EP1286692A4
(en)
|
2000-04-25 |
2004-11-17 |
Idec Pharma Corp |
INTRATHECAL ADMINISTRATION OF RITUXIMAB FOR THE TREATMENT OF LYMPHOMAS OF THE CENTRAL NERVOUS SYSTEM
|
|
EP1299128A2
(en)
|
2000-06-20 |
2003-04-09 |
Idec Pharmaceuticals Corporation |
Cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination
|
|
WO2001097843A2
(en)
|
2000-06-22 |
2001-12-27 |
University Of Iowa Research Foundation |
Methods for enhancing antibody-induced cell lysis and treating cancer
|
|
US6960597B2
(en)
|
2000-06-30 |
2005-11-01 |
Orth-Mcneil Pharmaceutical, Inc. |
Aza-bridged-bicyclic amino acid derivatives as α4 integrin antagonists
|
|
AU6461201A
(en)
|
2000-07-12 |
2002-01-21 |
Idec Pharma Corp |
Treatment of b cell malignancies using combination of b cell depleting antibody and immune modulating antibody related applications
|
|
CN1325480C
(zh)
|
2000-08-18 |
2007-07-11 |
味之素株式会社 |
苯基丙氨酸衍生物
|
|
EP1311549A2
(en)
|
2000-08-22 |
2003-05-21 |
Micromet AG |
Composition for the elimination of autoreactive b-cells
|
|
US20020058029A1
(en)
|
2000-09-18 |
2002-05-16 |
Nabil Hanna |
Combination therapy for treatment of autoimmune diseases using B cell depleting/immunoregulatory antibody combination
|
|
AU2001290303A1
(en)
|
2000-09-29 |
2002-04-15 |
Ajinomoto Co., Inc. |
Novel phenylalanine derivatives
|
|
US6946292B2
(en)
|
2000-10-06 |
2005-09-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Cells producing antibody compositions with increased antibody dependent cytotoxic activity
|
|
US7064191B2
(en)
|
2000-10-06 |
2006-06-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for purifying antibody
|
|
US20020128448A1
(en)
|
2000-10-20 |
2002-09-12 |
Idec Pharmaceuticals Corporation |
Variant IgG3 Rituxan and therapeutic use thereof
|
|
US6866866B1
(en)
*
|
2000-11-03 |
2005-03-15 |
Andrx Labs, Llc |
Controlled release metformin compositions
|
|
JP4731793B2
(ja)
|
2000-12-28 |
2011-07-27 |
アルセア テクノロジーズ インコーポレイテッド |
抗体全体またはそのフラグメントの結晶、ならびにこの結晶を作製および使用するための方法
|
|
CA2433877C
(en)
|
2001-01-17 |
2014-11-18 |
Aptevo Research And Development Llc |
Binding domain-immunoglobulin fusion proteins
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7829084B2
(en)
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
|
WO2002096948A2
(en)
|
2001-01-29 |
2002-12-05 |
Idec Pharmaceuticals Corporation |
Engineered tetravalent antibodies and methods of use
|
|
EP1373321A2
(en)
|
2001-01-29 |
2004-01-02 |
Idec Pharmaceuticals Corporation |
Modified antibodies and methods of use
|
|
US20030103971A1
(en)
|
2001-11-09 |
2003-06-05 |
Kandasamy Hariharan |
Immunoregulatory antibodies and uses thereof
|
|
EP1383532B1
(en)
|
2001-04-02 |
2011-05-04 |
Genentech, Inc. |
Combination therapy
|
|
JP2005500018A
(ja)
|
2001-04-02 |
2005-01-06 |
アイデック ファーマスーティカルズ コーポレイション |
ＧｎＴＩＩＩと同時発現する組換え抗体
|
|
WO2003061694A1
(en)
|
2001-05-10 |
2003-07-31 |
Seattle Genetics, Inc. |
Immunosuppression of the humoral immune response by anti-cd20 antibodies
|
|
WO2002102312A2
(en)
|
2001-06-14 |
2002-12-27 |
Intermune, Inc. |
Combination therapy of gamma-interferon and b cell specific antibodies
|
|
US7321026B2
(en)
|
2001-06-27 |
2008-01-22 |
Skytech Technology Limited |
Framework-patched immunoglobulins
|
|
WO2003010135A1
(en)
|
2001-07-26 |
2003-02-06 |
Ajinomoto Co., Inc. |
Novel phenylpropionic acid derivatives
|
|
RU2321630C2
(ru)
|
2001-08-03 |
2008-04-10 |
Гликарт Биотекнолоджи АГ |
Гликозилированные антитела (варианты), обладающие повышенной антителозависимой клеточной цитотоксичностью
|
|
ATE443259T1
(de)
|
2001-09-20 |
2009-10-15 |
Univ Texas |
Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper- komplexe mit elisa-tests
|
|
US20030157108A1
(en)
|
2001-10-25 |
2003-08-21 |
Genentech, Inc. |
Glycoprotein compositions
|
|
CN1210307C
(zh)
|
2001-11-16 |
2005-07-13 |
上海中信国健药业有限公司 |
抗cd20人源化单克隆抗体
|
|
EP1463524A4
(en)
|
2001-12-07 |
2005-02-09 |
Chiron Corp |
THERAPEUTIC METHODS FOR TREATING NON-HODGKINIAN LYMPHOMA
|
|
JP4452899B2
(ja)
|
2001-12-13 |
2010-04-21 |
味の素株式会社 |
新規フェニルアラニン誘導体
|
|
US20040093621A1
(en)
|
2001-12-25 |
2004-05-13 |
Kyowa Hakko Kogyo Co., Ltd |
Antibody composition which specifically binds to CD20
|
|
CA2476166C
(en)
|
2002-02-14 |
2011-11-15 |
Immunomedics, Inc. |
Anti-cd20 antibodies and fusion proteins thereof and methods of use
|
|
US20040002587A1
(en)
|
2002-02-20 |
2004-01-01 |
Watkins Jeffry D. |
Fc region variants
|
|
AU2003211560A1
(en)
|
2002-02-20 |
2003-09-09 |
Ajinomoto Co., Inc. |
Novel phenylalanine derivative
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
EP1480666B1
(en)
*
|
2002-03-05 |
2012-06-13 |
Ramot at Tel-Aviv University Ltd. |
Immunizing composition and method for inducing an immune response against the beta-secretase cleavage site of amyloid precursor protein
|
|
US7166441B2
(en)
|
2002-03-12 |
2007-01-23 |
Perseptive Biosystems Inc. |
Method and apparatus for the identification and quantification of biomolecules
|
|
US20030180292A1
(en)
|
2002-03-14 |
2003-09-25 |
Idec Pharmaceuticals |
Treatment of B cell malignancies using anti-CD40L antibodies in combination with anti-CD20 antibodies and/or chemotherapeutics and radiotherapy
|
|
WO2003084569A1
(en)
*
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Drug containing antibody composition
|
|
US20040132140A1
(en)
|
2002-04-09 |
2004-07-08 |
Kyowa Hakko Kogyo Co., Ltd. |
Production process for antibody composition
|
|
CN102911987B
(zh)
*
|
2002-04-09 |
2015-09-30 |
协和发酵麒麟株式会社 |
基因组被修饰的细胞
|
|
US20050031613A1
(en)
*
|
2002-04-09 |
2005-02-10 |
Kazuyasu Nakamura |
Therapeutic agent for patients having human FcgammaRIIIa
|
|
JP4628679B2
(ja)
*
|
2002-04-09 |
2011-02-09 |
協和発酵キリン株式会社 |
Ｇｄｐ−フコースの輸送に関与する蛋白質の活性が低下または欠失した細胞
|
|
AU2003236018A1
(en)
*
|
2002-04-09 |
2003-10-20 |
Kyowa Hakko Kirin Co., Ltd. |
METHOD OF ENHANCING ACTIVITY OF ANTIBODY COMPOSITION OF BINDING TO FcGamma RECEPTOR IIIa
|
|
JPWO2003089410A1
(ja)
|
2002-04-19 |
2005-08-25 |
協和醗酵工業株式会社 |
フェニルアラニン誘導体
|
|
US20030219818A1
(en)
|
2002-05-10 |
2003-11-27 |
Bohen Sean P. |
Methods and compositions for determining neoplastic disease responsiveness to antibody therapy
|
|
WO2004032828A2
(en)
|
2002-07-31 |
2004-04-22 |
Seattle Genetics, Inc. |
Anti-cd20 antibody-drug conjugates for the treatment of cancer and immune disorders
|
|
PL216630B1
(pl)
|
2002-10-17 |
2014-04-30 |
Genmab As |
Izolowane ludzkie przeciwciało monoklonalne wiążące ludzki CD20, związane z tym przeciwciałem transfektoma, komórka gospodarza, transgeniczne zwierzę lub roślina, kompozycja, immunokoniugat, cząsteczka bispecyficzna, wektor ekspresyjny, kompozycja farmaceutyczna, zastosowanie medyczne, zestaw oraz przeciwciało antyidiotypowe i jego zastosowanie
|
|
WO2004060053A2
(en)
|
2002-12-16 |
2004-07-22 |
Genentech, Inc. |
Transgenic mice expressing human cd20
|
|
ES2347241T3
(es)
|
2002-12-16 |
2010-10-27 |
Genentech, Inc. |
Variantes de inmunoglobulina y sus utilizaciones.
|
|
US7534427B2
(en)
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
US8084582B2
(en)
*
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
|
KR101118460B1
(ko)
|
2003-04-09 |
2012-04-13 |
허큘레스 인코포레이티드 |
컨디셔닝 용도에서의 양이온성의 산화된 다당류
|
|
EP2062916A3
(en)
|
2003-04-09 |
2009-08-19 |
Genentech, Inc. |
Therapy of autoimmune disease in a patient with an inadequate response to a TNF-Alpha inhibitor
|
|
WO2005000901A2
(en)
|
2003-05-09 |
2005-01-06 |
Duke University |
Cd20-specific antibodies and methods of employing same
|
|
AR044388A1
(es)
|
2003-05-20 |
2005-09-07 |
Applied Molecular Evolution |
Moleculas de union a cd20
|
|
US20050163775A1
(en)
|
2003-06-05 |
2005-07-28 |
Genentech, Inc. |
Combination therapy for B cell disorders
|
|
AU2004256042A1
(en)
|
2003-06-05 |
2005-01-20 |
Genentech, Inc. |
BlyS antagonists and uses thereof
|
|
WO2004113826A2
(en)
*
|
2003-06-19 |
2004-12-29 |
Zygo Corporation |
Compensation for imperfections in a measurement object and for beam misalignments in plane mirror interferometers
|
|
AU2004261176B2
(en)
|
2003-07-25 |
2010-05-20 |
Bally Gaming International, Inc. |
Uniquely identifiable casino gaming chips
|
|
RU2370775C2
(ru)
|
2003-07-29 |
2009-10-20 |
Дженентек, Инк. |
Анализ нейтрализующих антител и его применение
|
|
WO2005014618A2
(en)
|
2003-08-08 |
2005-02-17 |
Immunomedics, Inc. |
Bispecific antibodies for inducing apoptosis of tumor and diseased cells
|
|
US8147832B2
(en)
|
2003-08-14 |
2012-04-03 |
Merck Patent Gmbh |
CD20-binding polypeptide compositions and methods
|
|
KR20060132554A
(ko)
*
|
2003-08-29 |
2006-12-21 |
제넨테크, 인크. |
안과 질병의 항-ｃｄ２０ 치료
|
|
US20080241884A1
(en)
|
2003-10-08 |
2008-10-02 |
Kenya Shitara |
Fused Protein Composition
|
|
US20070134759A1
(en)
|
2003-10-09 |
2007-06-14 |
Harue Nishiya |
Process for producing antibody composition by using rna inhibiting the function of alpha1,6-fucosyltransferase
|
|
ES2672640T3
(es)
|
2003-11-05 |
2018-06-15 |
Roche Glycart Ag |
Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas
|
|
US20050191297A1
(en)
|
2003-12-19 |
2005-09-01 |
Genentech, Inc. |
Detection of CD20 in transplant rejection
|
|
MXPA06006864A
(es)
|
2003-12-19 |
2006-08-23 |
Genentech Inc |
Deteccion de cd20 en la terapia de enfermedades autoinmunes.
|
|
EP1706424B1
(en)
|
2004-01-12 |
2009-07-22 |
Applied Molecular Evolution, Inc. |
Fc region variants
|
|
US7290012B2
(en)
|
2004-01-16 |
2007-10-30 |
International Business Machines Corporation |
Apparatus, system, and method for passing data between an extensible markup language document and a hierarchical database
|
|
JP2007532680A
(ja)
|
2004-04-16 |
2007-11-15 |
ジェネンテック・インコーポレーテッド |
疾患の治療方法
|
|
AU2005244751A1
(en)
|
2004-04-16 |
2005-12-01 |
Genentech, Inc. |
Method for augmenting B cell depletion
|
|
EP1745288A2
(en)
*
|
2004-04-16 |
2007-01-24 |
Genentech, Inc. |
Assay for antibodies
|
|
US7850962B2
(en)
|
2004-04-20 |
2010-12-14 |
Genmab A/S |
Human monoclonal antibodies against CD20
|
|
ZA200608982B
(en)
|
2004-05-05 |
2008-06-25 |
Genentech Inc |
Preventing autoimmune disease by using an anti-CD20 antibody
|
|
CA2562800A1
(en)
|
2004-05-15 |
2005-12-01 |
Genentech, Inc. |
Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
|
|
US7618627B2
(en)
|
2004-06-03 |
2009-11-17 |
The Regents Of The University Of California |
Method of increasing radiation sensitivity by inhibition of beta one integrin
|
|
BRPI0510915A
(pt)
|
2004-06-04 |
2007-11-13 |
Genentech Inc |
método para o tratamento da esclerose múltipla e artigo manufaturado
|
|
PA8635501A1
(es)
|
2004-06-04 |
2006-06-02 |
Genentech Inc |
Uso de un anticuerpo para el tratamiento del lupus
|
|
WO2006005477A1
(en)
*
|
2004-07-09 |
2006-01-19 |
Schering Ag |
Combination therapywith radiolabeled anti-cd20 antibody in the treatment of b-cell lymphoma
|
|
JP4501572B2
(ja)
*
|
2004-07-20 |
2010-07-14 |
富士ゼロックス株式会社 |
書類管理装置および書類管理システム
|
|
CA2573359A1
(en)
|
2004-07-22 |
2006-02-02 |
Genentech, Inc. |
Method of treating sjogren's syndrome
|
|
US20060067930A1
(en)
|
2004-08-19 |
2006-03-30 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
CN101048428A
(zh)
|
2004-09-08 |
2007-10-03 |
健泰科生物技术公司 |
利用死亡受体配体和cd20抗体的方法
|
|
RU2007112929A
(ru)
|
2004-09-08 |
2008-10-20 |
Дженентек, Инк. (Us) |
Способы применения лигандов рецептора смерти и антител к cd20
|
|
ZA200702335B
(en)
|
2004-10-05 |
2009-05-27 |
Genentech Inc |
Method for treating vasculitis
|
|
AR052774A1
(es)
|
2004-10-08 |
2007-04-04 |
Wyeth Corp |
Inmunoterapia para trastornos autoinmunes
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
FR2879204B1
(fr)
*
|
2004-12-15 |
2007-02-16 |
Lab Francais Du Fractionnement |
Anticorps cytotoxique dirige contre les proliferations hematopoietiques lymphoides de type b.
|
|
BRPI0518105A
(pt)
|
2004-12-17 |
2008-11-04 |
Genentech Inc |
uso de antagonista da angiogênese e uso de anticorpo anti-vegf
|
|
JP2008525041A
(ja)
|
2004-12-22 |
2008-07-17 |
ジェネンテック・インコーポレーテッド |
可溶性多膜貫通型タンパク質の産生方法
|
|
EP1841454A4
(en)
|
2005-01-13 |
2009-07-22 |
Genentech Inc |
Methods of Treatment
|
|
DOP2006000029A
(es)
|
2005-02-07 |
2006-08-15 |
Genentech Inc |
Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
|
|
TW200714289A
(en)
|
2005-02-28 |
2007-04-16 |
Genentech Inc |
Treatment of bone disorders
|
|
ATE517183T1
(de)
|
2005-03-31 |
2011-08-15 |
Biomedics Inc |
Monoklonaler antikörper gegen cd20
|
|
AR053579A1
(es)
|
2005-04-15 |
2007-05-09 |
Genentech Inc |
Tratamiento de la enfermedad inflamatoria intestinal (eii)
|
|
ZA200708857B
(en)
|
2005-04-22 |
2009-01-28 |
Genentech Inc |
Method for treating dementia or alzheimer's disease with a CD30 antibody
|
|
RU2007142523A
(ru)
|
2005-05-18 |
2009-06-27 |
БИОГЕН ИДЕК Инк. (US) |
Способы лечения фиброзных состояний
|
|
EP1902320B1
(en)
|
2005-05-20 |
2010-03-10 |
Genentech, Inc. |
Pretreatment of a biological sample from an autoimmune disease subject
|
|
MX2007014673A
(es)
|
2005-05-24 |
2008-04-08 |
Avestha Gengraine Tech Pvt Ltd |
Metodo para la produccion de un anticuerpo monoclonal para cd20 para el tratamiento de linfoma de celular b.
|
|
US20070014720A1
(en)
|
2005-06-02 |
2007-01-18 |
Gadi Gazit-Bornstein |
Antibodies directed to CD20 and uses thereof
|
|
EP1888638A2
(en)
|
2005-06-03 |
2008-02-20 |
Genentech, Inc. |
Method of producing antibodies with modified fucosylation level
|
|
CN1290864C
(zh)
|
2005-07-11 |
2006-12-20 |
中国人民解放军军事医学科学院生物工程研究所 |
一种抗cd20嵌合抗体
|
|
CA2616386A1
(en)
|
2005-07-25 |
2007-02-01 |
Trubion Pharmaceuticals Inc. |
Single dose use of cd20-specific binding molecules
|
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
|
AU2006318539B2
(en)
|
2005-11-23 |
2012-09-13 |
Genentech, Inc. |
Methods and compositions related to B cell assays
|
|
WO2007064911A1
(en)
|
2005-12-02 |
2007-06-07 |
Biogen Idec Inc. |
Anti-mouse cd20 antibodies and uses thereof
|
|
CL2007001536A1
(es)
*
|
2006-05-30 |
2008-01-25 |
Genentech Inc |
Anticuerpos anti-cd22; polinucleotidos que los codifica; vector y celula huesped que los comprende; metodo de fabricacion; metodo de deteccion del anticuerpo en una muestra biologica; inmunoconjugado que comprende al anticuerpo; composicion que lo comprende y su uso para tratar trastornos proliferativos de celulas b.
|
|
EP2046383B1
(en)
|
2006-07-04 |
2014-11-19 |
Genmab A/S |
Cd20 binding molecules for the treatment of copd
|
|
JP2010502841A
(ja)
|
2006-09-08 |
2010-01-28 |
トーソー エスエムディー，インク． |
非常に小さな結晶粒径と高エレクトロマイグレーション抵抗とを有する銅スパッタリングターゲットおよびそれを製造する方法
|
|
CL2008000948A1
(es)
|
2007-04-02 |
2008-10-10 |
Genentech Inc |
Uso de un antagonista de celulas b para tratar la artritis reumatoide a condicion que se observe la presencia de polimorfismo de nucleotido simple, epitope compartido o ambos en una muestra genetica del paciente.
|
|
WO2008157282A1
(en)
|
2007-06-18 |
2008-12-24 |
Genentech, Inc. |
Biological markers predictive of rheumatoid arthritis response to b-cell antagonists
|
|
MX354993B
(es)
|
2007-07-09 |
2018-03-28 |
Genentech Inc |
Prevención de reducción de enlaces de disulfuro durante la producción recombinante de polipéptidos.
|
|
US8144978B2
(en)
|
2007-08-01 |
2012-03-27 |
Tandent Vision Science, Inc. |
System and method for identifying complex tokens in an image
|
|
MX2010002406A
(es)
|
2007-09-05 |
2010-04-27 |
Hoffmann La Roche |
Terapia de combinacion con anticuerpos anti-cd20 de tipo i y de tipo ii.
|
|
GB0718684D0
(en)
|
2007-09-24 |
2007-10-31 |
Roche Products Ltd |
Treatment method
|
|
US20090098118A1
(en)
|
2007-10-15 |
2009-04-16 |
Thomas Friess |
Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent
|
|
US20090110688A1
(en)
|
2007-10-24 |
2009-04-30 |
Georg Fertig |
Combination therapy of type ii anti-cd20 antibody with a proteasome inhibitor
|
|
BRPI0817182A2
(pt)
|
2007-10-30 |
2015-03-17 |
Genentech Inc |
Método para purificar um anticorpo e composições
|
|
DK2234600T3
(da)
|
2007-12-21 |
2014-09-08 |
Hoffmann La Roche |
Antistofformulering
|
|
EP2235056A1
(en)
|
2007-12-21 |
2010-10-06 |
Genentech, Inc. |
Crystallization of anti-cd20 antibodies
|
|
AU2008342956A1
(en)
|
2007-12-21 |
2009-07-09 |
Genentech, Inc. |
Therapy of rituximab-refractory rheumatoid arthritis patients
|
|
MY163544A
(en)
|
2008-03-25 |
2017-09-29 |
Roche Glycart Ag |
Use of a type ii anti-cd20 antibody with increased antibody dependent cellular cytotoxicity (adcc) in combination with cyclophosphamide, vincristine and doxorubicine for treating non-hodgkin's lymphomas
|
|
WO2009134738A1
(en)
|
2008-04-29 |
2009-11-05 |
Genentech, Inc. |
Responses to immunizations in rheumatoid arthritis patients treated with a cd20 antibody
|
|
TW201438738A
(zh)
|
2008-09-16 |
2014-10-16 |
建南德克公司 |
治療進展型多發性硬化症之方法
|
|
KR20110097772A
(ko)
|
2008-11-17 |
2011-08-31 |
제넨테크, 인크. |
생리적 조건하에 거대분자의 응집을 감소시키는 방법 및 제제
|
|
AR074357A1
(es)
|
2008-11-17 |
2011-01-12 |
Genentech Inc |
Metodo y formulacion para reducir la agregacion de una macromolecula bajo condiciones fisiologicas. metodo de dialisis in vitro
|
|
CN102597268B
(zh)
*
|
2009-09-03 |
2017-09-22 |
弗·哈夫曼-拉罗切有限公司 |
用于治疗、诊断和监控类风湿性关节炎的方法
|
|
KR20160061492A
(ko)
|
2014-11-21 |
2016-06-01 |
삼성디스플레이 주식회사 |
휴대용 먼지 센서 및 이를 이용한 휴대전화
|