JP2016047845A5 - - Google Patents
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- JP2016047845A5 JP2016047845A5 JP2015247222A JP2015247222A JP2016047845A5 JP 2016047845 A5 JP2016047845 A5 JP 2016047845A5 JP 2015247222 A JP2015247222 A JP 2015247222A JP 2015247222 A JP2015247222 A JP 2015247222A JP 2016047845 A5 JP2016047845 A5 JP 2016047845A5
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- JP
- Japan
- Prior art keywords
- nucleic acid
- sequence
- cells
- seq
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26020209P | 2009-11-11 | 2009-11-11 | |
| US61/260,202 | 2009-11-11 | ||
| EP09014136A EP2322555A1 (en) | 2009-11-11 | 2009-11-11 | Antibodies specific for claudin 6 (CLDN6) |
| EP09014136.7 | 2009-11-11 | ||
| US36161810P | 2010-07-06 | 2010-07-06 | |
| EP10006956.6 | 2010-07-06 | ||
| US61/361,618 | 2010-07-06 | ||
| EP10006956 | 2010-07-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012538239A Division JP5889196B2 (ja) | 2009-11-11 | 2010-11-11 | クローディン6(cldn6)に特異的な抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017075017A Division JP6502992B2 (ja) | 2009-11-11 | 2017-04-05 | クローディン6(cldn6)に特異的な抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016047845A JP2016047845A (ja) | 2016-04-07 |
| JP2016047845A5 true JP2016047845A5 (https=) | 2016-06-23 |
| JP6125604B2 JP6125604B2 (ja) | 2017-05-10 |
Family
ID=43480734
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012538239A Active JP5889196B2 (ja) | 2009-11-11 | 2010-11-11 | クローディン6(cldn6)に特異的な抗体 |
| JP2015247222A Active JP6125604B2 (ja) | 2009-11-11 | 2015-12-18 | クローディン6(cldn6)に特異的な抗体 |
| JP2017075017A Active JP6502992B2 (ja) | 2009-11-11 | 2017-04-05 | クローディン6(cldn6)に特異的な抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012538239A Active JP5889196B2 (ja) | 2009-11-11 | 2010-11-11 | クローディン6(cldn6)に特異的な抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017075017A Active JP6502992B2 (ja) | 2009-11-11 | 2017-04-05 | クローディン6(cldn6)に特異的な抗体 |
Country Status (29)
| Country | Link |
|---|---|
| US (5) | US9487584B2 (https=) |
| EP (4) | EP3305813B1 (https=) |
| JP (3) | JP5889196B2 (https=) |
| KR (4) | KR102317098B1 (https=) |
| CN (4) | CN111875703B (https=) |
| AU (3) | AU2010318316B2 (https=) |
| BR (1) | BR112012011143B1 (https=) |
| CA (2) | CA2775373C (https=) |
| CY (2) | CY1120300T1 (https=) |
| DK (2) | DK3305813T3 (https=) |
| ES (3) | ES2649389T3 (https=) |
| HR (2) | HRP20171749T1 (https=) |
| HU (2) | HUE049404T2 (https=) |
| IL (2) | IL218628B (https=) |
| LT (2) | LT2499161T (https=) |
| ME (1) | ME02943B (https=) |
| MX (3) | MX385874B (https=) |
| NO (1) | NO2499161T3 (https=) |
| NZ (2) | NZ716587A (https=) |
| PL (3) | PL3689911T3 (https=) |
| PT (2) | PT2499161T (https=) |
| RS (2) | RS56502B1 (https=) |
| RU (1) | RU2675997C2 (https=) |
| SG (2) | SG10202110692WA (https=) |
| SI (2) | SI2499161T1 (https=) |
| SM (1) | SMT201700566T1 (https=) |
| UA (2) | UA128302C2 (https=) |
| WO (1) | WO2011057788A1 (https=) |
| ZA (1) | ZA201202418B (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| US12492253B1 (en) * | 2008-02-25 | 2025-12-09 | Xencor, Inc. | Anti-human C5 antibodies |
| LT2398902T (lt) | 2009-02-20 | 2023-12-27 | Astellas Pharma Inc. | Vėžio diagnostikos ir gydymo būdai bei kompozicijos |
| NZ716587A (en) | 2009-11-11 | 2017-10-27 | Ganymed Pharmaceuticals Ag | Antibodies specific for claudin 6 (cldn6) |
| EP2404936A1 (en) | 2010-07-06 | 2012-01-11 | Ganymed Pharmaceuticals AG | Cancer therapy using CLDN6 target-directed antibodies in vivo |
| RS67768B1 (sr) | 2010-11-30 | 2026-03-31 | Chugai Pharmaceutical Co Ltd | Terapijski agens koji indukuje citotoksičnost |
| US9321842B2 (en) * | 2011-05-13 | 2016-04-26 | Ganymed Pharmaceuticals Ag | Antibodies for treatment of cancer |
| ES2703936T3 (es) * | 2011-05-13 | 2019-03-13 | Ganymed Pharmaceuticals Gmbh | Anticuerpos para el tratamiento de un cáncer que expresa la claudina 6 |
| CN103320381B (zh) * | 2012-03-23 | 2015-04-15 | 上海市儿童医院 | 一种多能干细胞表面标志物及其用途 |
| PL3489261T3 (pl) | 2012-08-24 | 2021-08-16 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
| EP3766903A3 (en) * | 2012-11-13 | 2021-02-17 | BioNTech SE | Bispecific anti claudin xcd3 antibodies for treatment of claudin expressing cancer diseases |
| WO2014075788A1 (en) * | 2012-11-13 | 2014-05-22 | Biontech Ag | Agents for treatment of claudin expressing cancer diseases |
| EP3747465A1 (en) * | 2013-07-31 | 2020-12-09 | BioNTech AG | Diagnosis and therapy of cancer involving cancer stem cells |
| WO2015014376A1 (en) * | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnosis and therapy of cancer involving cancer stem cells |
| PE20160870A1 (es) * | 2013-11-06 | 2016-09-09 | Abbvie Stemcentrx Llc | Anticuerpos anti-claudina novedosos y metodos de uso |
| TWI712421B (zh) | 2013-11-11 | 2020-12-11 | 日商中外製藥股份有限公司 | 含改變的抗體可變區之抗原結合分子 |
| SI3126381T2 (sl) * | 2014-04-01 | 2022-05-31 | Biontech Cell&Gene Therapies Gmbh | Claudin-6-specifični imunoreceptorji in t-celični epitopi |
| MA40921A (fr) * | 2014-11-05 | 2017-09-12 | Abbvie Stemcentrx Llc | Récepteurs antigéniques chimériques anti-cldn et procédés d'utilisation |
| TWI880146B (zh) | 2014-11-11 | 2025-04-11 | 日商中外製藥股份有限公司 | 包含經改變之抗體可變區之抗原結合分子的資料庫 |
| IL299099B2 (en) | 2016-06-27 | 2025-07-01 | Univ California | Cancer treatment combinations |
| WO2018105560A1 (ja) * | 2016-12-07 | 2018-06-14 | 国立大学法人大阪大学 | Claudin 5抗体、及びその抗体を含有する医薬 |
| EP3623384A4 (en) * | 2017-05-08 | 2021-01-27 | Osaka University | ANTI-CLDN-5 ANTIBODY AND ACTIVE SUBSTANCE WITH THIS ANTIBODY |
| WO2019048040A1 (en) * | 2017-09-06 | 2019-03-14 | Ganymed Pharmaceuticals Gmbh | ANTIBODIES USEFUL IN THE DIAGNOSIS OF CANCER |
| IL301637B2 (en) | 2017-09-29 | 2024-10-01 | Daiichi Sankyo Co Ltd | Antibody-pyrrolobenzodiazepine derivative conjugate |
| TW201938194A (zh) | 2017-12-05 | 2019-10-01 | 日商中外製藥股份有限公司 | 包含結合cd3及cd137的改變的抗體可變區之抗原結合分子 |
| US20210054076A1 (en) * | 2018-01-05 | 2021-02-25 | Chugai Seiyaku Kabushiki Kaisha | Cytotoxicity-inducing therapeutic agent |
| US12493039B2 (en) | 2018-10-09 | 2025-12-09 | Fukushima Medical University | Biomarker for predicting the prognosis for an endometrial cancer patient |
| EP3924389A4 (en) | 2019-02-15 | 2023-06-14 | Integral Molecular, Inc. | CLAUDIN-6 ANTIBODIES AND THEIR USES |
| AU2020241896A1 (en) | 2019-03-20 | 2021-09-23 | The Regents Of The University Of California | Claudin-6 antibodies and drug conjugates |
| EP3950061A4 (en) | 2019-03-25 | 2022-11-16 | Daiichi Sankyo Company, Limited | ANTIBODY PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE |
| CR20220049A (es) | 2019-07-10 | 2022-03-02 | Chugai Pharmaceutical Co Ltd | Moléculas de unión a claudina-6 y usos de las mismas |
| CN111087465B (zh) | 2019-12-24 | 2020-12-08 | 广州医科大学 | 一种针对密蛋白6的抗体偶联药物及应用 |
| CA3174094A1 (en) | 2020-03-31 | 2021-10-07 | Shinya Ishii | Claudin-6 targeting multispecific antigen-binding molecules and uses thereof |
| CA3212530A1 (en) * | 2021-03-05 | 2022-09-09 | Shanghai GenBase Biotechnology Co., Ltd. | Anti-cldn6 antibody and use thereof |
| JP2024511319A (ja) | 2021-03-09 | 2024-03-13 | ゼンコア インコーポレイテッド | Cd3及びcldn6に結合するヘテロ二量体抗体 |
| JPWO2023053282A1 (https=) | 2021-09-29 | 2023-04-06 | ||
| WO2024022512A1 (en) * | 2022-07-29 | 2024-02-01 | Nanjing Legend Biotech Co., Ltd. | Claudin-6 binding moieties and uses thereof |
| TW202434302A (zh) | 2022-10-31 | 2024-09-01 | 日商安斯泰來製藥股份有限公司 | 包含類鐸受體7/8雙重促效劑化合物之抗體藥物複合體 |
| EP4626933A1 (en) | 2022-11-30 | 2025-10-08 | Integral Molecular, Inc. | Antibodies directed to claudin 6, including bispecific formats thereof |
| CN116064622B (zh) * | 2023-02-13 | 2023-10-13 | 优睿赛思(武汉)生物科技有限公司 | Claudin6-mCherry报告基因CHO-K1稳转细胞株制备及应用 |
| WO2024235175A1 (zh) | 2023-05-12 | 2024-11-21 | 智泽童康(广州)生物科技有限公司 | 抗cldn6抗体及其用途 |
| US12403202B2 (en) | 2023-05-25 | 2025-09-02 | The Regents Of The University Of California | Dosage of claudin-6 conjugates for cancer treatment |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
| CN119371534B (zh) * | 2024-08-21 | 2025-05-27 | 百吉生物医药(广州)股份有限公司 | 一种紧密连接蛋白抗体e02及其应用 |
| CN118754987B (zh) * | 2024-08-21 | 2025-02-11 | 广州百吉生物制药有限公司 | 一种紧密连接蛋白抗体h04及其应用 |
| CN119320451B (zh) * | 2024-08-21 | 2025-05-16 | 百吉生物医药(广州)股份有限公司 | 一种紧密连接蛋白抗体d03及其应用 |
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-
2010
- 2010-11-11 NZ NZ716587A patent/NZ716587A/en unknown
- 2010-11-11 SI SI201031568T patent/SI2499161T1/sl unknown
- 2010-11-11 US US13/503,461 patent/US9487584B2/en active Active
- 2010-11-11 PT PT107788770T patent/PT2499161T/pt unknown
- 2010-11-11 ME MEP-2017-261A patent/ME02943B/me unknown
- 2010-11-11 ES ES10778877.0T patent/ES2649389T3/es active Active
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