|
EP3208612B1
(en)
|
2008-04-09 |
2019-09-18 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
MA40835A
(fr)
|
2014-10-23 |
2017-08-29 |
Biogen Ma Inc |
Anticorps anti-gpiib/iiia et leurs utilisations
|
|
MA40861A
(fr)
*
|
2014-10-31 |
2017-09-05 |
Biogen Ma Inc |
Anticorps anti-glycoprotéines iib/iiia
|
|
EP3458485B1
(en)
|
2016-05-19 |
2021-12-29 |
The General Hospital Corporation |
Tethered interleukin-2 to its receptor il-2rbeta, a platform to enhance natural killer and regulatory t cell activity
|
|
CN110662552A
(zh)
|
2016-11-30 |
2020-01-07 |
昂科梅德制药有限公司 |
包含tigit结合剂的癌症治疗方法
|
|
RS64576B1
(sr)
|
2017-05-01 |
2023-10-31 |
Agenus Inc |
Anti-tigit antitela i postupci njihove primene
|
|
IL272227B2
(en)
*
|
2017-07-27 |
2025-09-01 |
iTeos Belgium SA |
Anti-tigit antibodies
|
|
JP2021534196A
(ja)
*
|
2018-08-23 |
2021-12-09 |
シージェン インコーポレイテッド |
抗ｔｉｇｉｔ抗体
|
|
US11376255B2
(en)
|
2018-09-11 |
2022-07-05 |
iTeos Belgium SA |
Thiocarbamate derivatives as A2A inhibitors, pharmaceutical composition thereof and combinations with anticancer agents
|
|
EP4410375A3
(en)
|
2018-09-11 |
2024-11-06 |
iTeos Belgium SA |
Thiocarbamate derivatives as a2a inhibitors, pharmaceutical composition thereof and combinations with anticancer agents
|
|
CN113614109A
(zh)
|
2018-12-21 |
2021-11-05 |
Ose免疫疗法公司 |
双功能抗pd-1/il-7分子
|
|
WO2020165374A1
(en)
|
2019-02-14 |
2020-08-20 |
Ose Immunotherapeutics |
Bifunctional molecule comprising il-15ra
|
|
EP3947640A4
(en)
|
2019-04-02 |
2022-12-14 |
The Brigham & Women's Hospital, Inc. |
PROCEDURE FOR DETERMINING THE PROGRESSION OF PRIMARY MELANOMA
|
|
KR102332847B1
(ko)
*
|
2019-06-13 |
2021-12-01 |
주식회사 녹십자 |
Tigit에 대한 항체 및 이의 용도
|
|
AU2020298324A1
(en)
*
|
2019-06-21 |
2022-01-27 |
Single Cell Technology, Inc. |
Anti-TIGIT antibodies
|
|
AU2020378335A1
(en)
*
|
2019-11-05 |
2022-04-07 |
Merck Patent Gmbh |
Anti-TIGIT antibodies and uses thereof
|
|
AU2020406083A1
(en)
|
2019-12-17 |
2022-06-16 |
Boehringer Ingelheim International Gmbh |
Bifunctional molecules comprising an IL-7 variant
|
|
CN112409450B
(zh)
*
|
2020-03-29 |
2023-01-24 |
郑州大学 |
TIGIT-IgV的亲和剂及其应用
|
|
CN113563470B
(zh)
|
2020-04-29 |
2023-02-10 |
广州昂科免疫生物技术有限公司 |
结合tigit抗原的抗体及其制备方法与应用
|
|
CA3176497A1
(en)
|
2020-05-07 |
2021-11-11 |
Fatima MECHTA-GRIGORIOU |
Antxr1 as a biomarker of immunosuppressive fibroblast populations and its use for predicting response to immunotherapy
|
|
CN111995681B
(zh)
*
|
2020-05-09 |
2022-03-08 |
华博生物医药技术（上海）有限公司 |
抗tigit的抗体、其制备方法和应用
|
|
BR112022024221A2
(pt)
|
2020-06-02 |
2022-12-20 |
Arcus Biosciences Inc |
Anticorpos para tigit
|
|
CN115916348A
(zh)
|
2020-06-18 |
2023-04-04 |
基因泰克公司 |
使用抗tigit抗体和pd-1轴结合拮抗剂的治疗
|
|
WO2021258337A1
(en)
*
|
2020-06-24 |
2021-12-30 |
Huahui Health Ltd. |
Human monoclonal antibodies against tigit for immune related diseases
|
|
CN111718415B
(zh)
*
|
2020-07-03 |
2021-02-23 |
上海洛启生物医药技术有限公司 |
一种抗tigit纳米抗体及其应用
|
|
TW202216778A
(zh)
|
2020-07-15 |
2022-05-01 |
美商安進公司 |
Ｔｉｇｉｔ及ｃｄ１１２ｒ阻斷
|
|
EP4192883A4
(en)
*
|
2020-08-05 |
2024-12-04 |
Crystal Bioscience Inc. |
Anti-tigit antibody and methods of use thereof
|
|
JP2023545099A
(ja)
|
2020-10-08 |
2023-10-26 |
アフィメド ゲーエムベーハー |
三重特異性バインダー
|
|
WO2022112198A1
(en)
|
2020-11-24 |
2022-06-02 |
Worldwide Innovative Network |
Method to select the optimal immune checkpoint therapies
|
|
WO2022148781A1
(en)
|
2021-01-05 |
2022-07-14 |
Institut Curie |
Combination of mcoln activators and immune checkpoint inhibitors
|
|
EP4294948A1
(en)
|
2021-02-17 |
2023-12-27 |
iTeos Belgium SA |
Compounds, compositions and methods of treatment thereof
|
|
AU2022253351A1
(en)
|
2021-04-09 |
2023-10-12 |
Boehringer Ingelheim International Gmbh |
New scaffold for bifunctional molecules with improved properties
|
|
EP4320156A1
(en)
|
2021-04-09 |
2024-02-14 |
Ose Immunotherapeutics |
Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
|
|
AR125753A1
(es)
|
2021-05-04 |
2023-08-09 |
Agenus Inc |
Anticuerpos anti-tigit, anticuerpos anti-cd96 y métodos de uso de estos
|
|
CN118871463A
(zh)
|
2021-07-28 |
2024-10-29 |
基因泰克公司 |
用于治疗癌症的方法和组合物
|
|
CA3216098A1
(en)
|
2021-07-30 |
2023-02-02 |
Uwe Reusch |
Duplexbodies
|
|
TW202321308A
(zh)
|
2021-09-30 |
2023-06-01 |
美商建南德克公司 |
使用抗ｔｉｇｉｔ抗體、抗ｃｄ３８抗體及ｐｄ—１軸結合拮抗劑治療血液癌症的方法
|
|
CA3256561A1
(en)
|
2022-05-02 |
2023-11-09 |
Arcus Biosciences, Inc. |
Anti-tigit antibodies and their uses
|
|
EP4537107A2
(en)
|
2022-06-07 |
2025-04-16 |
Genentech, Inc. |
Method for determining the efficacy of a lung cancer treatment comprising an anti-pd-l1 antagonist and an anti-tigit antagonist antibody
|
|
WO2024003360A1
(en)
|
2022-07-01 |
2024-01-04 |
Institut Curie |
Biomarkers and uses thereof for the treatment of neuroblastoma
|
|
WO2024028386A1
(en)
|
2022-08-02 |
2024-02-08 |
Ose Immunotherapeutics |
Multifunctional molecule directed against cd28
|
|
CN121358499A
(zh)
|
2023-03-30 |
2026-01-16 |
Ose免疫疗法 |
靶向活化的免疫细胞以表达免疫细胞增强分子的基于脂质的纳米粒及其用途
|
|
AU2024254671A1
(en)
|
2023-03-30 |
2025-10-02 |
Ose Immunotherapeutics |
Method of synthesis of targeted lipid nanoparticle and uses thereof
|
|
WO2025068461A1
(en)
|
2023-09-29 |
2025-04-03 |
Negio Therapeutics |
Guanfacine derivatives and their use in treating cancer
|
|
WO2025068452A1
(en)
|
2023-09-29 |
2025-04-03 |
Negio Therapeutics |
Guanfacine derivatives and their use in treating cancer
|
|
WO2025132831A1
(en)
|
2023-12-19 |
2025-06-26 |
Universite D'aix-Marseille |
N-heteroaryl derivatives and uses thereof for treating cancer
|
|
WO2025242836A1
(en)
|
2024-05-22 |
2025-11-27 |
Ose Immunotherapeutics |
Molecules comprising masking linkers and uses thereof for the treatment of auto-immune or inflammatory diseases and disorders
|
|
WO2025242835A1
(en)
|
2024-05-22 |
2025-11-27 |
Ose Immunotherapeutics |
Molecules comprising masking linkers and uses thereof for the treatment of cancer
|
|
WO2025255297A1
(en)
*
|
2024-06-05 |
2025-12-11 |
Agilent Technologies, Inc. |
Anti-human tigit antibodies for in vitro diagnostics
|
|
WO2025262250A1
(en)
|
2024-06-20 |
2025-12-26 |
Negio Therapeutics |
Guanfacine derivatives and their uses
|
|
WO2026068705A1
(en)
|
2024-09-26 |
2026-04-02 |
Ose Immunotherapeutics |
Lipid-based nanoparticles comprising non-glycosylated fc domains and uses thereof
|