JP2023516004A5 - - Google Patents

Info

Publication number
JP2023516004A5
JP2023516004A5 JP2022551742A JP2022551742A JP2023516004A5 JP 2023516004 A5 JP2023516004 A5 JP 2023516004A5 JP 2022551742 A JP2022551742 A JP 2022551742A JP 2022551742 A JP2022551742 A JP 2022551742A JP 2023516004 A5 JP2023516004 A5 JP 2023516004A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
acid sequence
cdr1
cdr2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022551742A
Other languages
English (en)
Japanese (ja)
Other versions
JP7702961B2 (ja
JP2023516004A (ja
JP7702961B6 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2021/078051 external-priority patent/WO2021170068A1/en
Publication of JP2023516004A publication Critical patent/JP2023516004A/ja
Publication of JP2023516004A5 publication Critical patent/JP2023516004A5/ja
Publication of JP7702961B2 publication Critical patent/JP7702961B2/ja
Application granted granted Critical
Publication of JP7702961B6 publication Critical patent/JP7702961B6/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022551742A 2020-02-28 2021-02-26 抗cd137コンストラクト、多重特異性抗体及びその使用 Active JP7702961B6 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2020077148 2020-02-28
CNPCT/CN2020/077148 2020-02-28
PCT/CN2021/078051 WO2021170068A1 (en) 2020-02-28 2021-02-26 Anti-cd137 constructs, multispecific antibody and uses thereof

Publications (4)

Publication Number Publication Date
JP2023516004A JP2023516004A (ja) 2023-04-17
JP2023516004A5 true JP2023516004A5 (https=) 2024-02-27
JP7702961B2 JP7702961B2 (ja) 2025-07-04
JP7702961B6 JP7702961B6 (ja) 2025-07-17

Family

ID=77489868

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022551742A Active JP7702961B6 (ja) 2020-02-28 2021-02-26 抗cd137コンストラクト、多重特異性抗体及びその使用

Country Status (9)

Country Link
US (1) US20230067770A1 (https=)
EP (1) EP4110827A4 (https=)
JP (1) JP7702961B6 (https=)
KR (1) KR20220148228A (https=)
CN (1) CN115190889A (https=)
AU (1) AU2021228077A1 (https=)
CA (1) CA3169943A1 (https=)
WO (1) WO2021170068A1 (https=)
ZA (1) ZA202210626B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114450306B (zh) * 2019-07-26 2024-04-05 Abl生物公司 抗egfr/抗4-1bb双特异性抗体及其用途
AU2022260298A1 (en) * 2021-04-23 2023-11-02 Shanghai Henlius Biotech, Inc. Anti-gpc3 antibodies, multispecific antibodies and methods of use
WO2024040194A1 (en) 2022-08-17 2024-02-22 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering
AU2024279278A1 (en) 2023-05-31 2025-12-18 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
US20250127728A1 (en) 2023-10-05 2025-04-24 Capstan Therapeutics, Inc. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
WO2025101526A1 (en) * 2023-11-06 2025-05-15 Beijing Starmab Biomed Technology Ltd Multi-specific cancer-targeting antibodies
US20250302763A1 (en) 2024-02-22 2025-10-02 Capstan Therapeutics, Inc. Immune engineering amplification
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles
WO2026037257A1 (en) * 2024-08-12 2026-02-19 Shanghai Henlius Biotech, Inc. Anti-egfr/met multispecific antibodies and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7288638B2 (en) * 2003-10-10 2007-10-30 Bristol-Myers Squibb Company Fully human antibodies against human 4-1BB
MX337040B (es) * 2010-09-09 2016-02-09 Pfizer Moleculas de union a 4-1bb.
EP3613433B1 (en) * 2014-05-30 2022-01-05 Shanghai Henlius Biotech, Inc. Anti-epidermal growth factor receptor (egfr) antibodies
EP3445788B1 (en) * 2016-04-22 2022-01-19 Alligator Bioscience AB Novel bispecific polypeptides against cd137
WO2018031258A1 (en) * 2016-08-12 2018-02-15 Janssen Biotech, Inc. Engineered antibodies and other fc-domain containing molecules with enhanced agonism and effector functions
EP3470428A1 (en) * 2017-10-10 2019-04-17 Numab Innovation AG Antibodies targeting cd137 and methods of use thereof

Similar Documents

Publication Publication Date Title
JP2023516004A5 (https=)
JP2023509448A5 (https=)
CN102369214B (zh) 三价、双特异性抗体
JP2023516941A5 (https=)
JP2023543031A5 (https=)
JP2021098733A5 (https=)
US20220002398A1 (en) ANTI-oxMIF/ANTI-CD3 ANTIBODY FOR CANCER TREATMENT
TWI874613B (zh) 微型導引和導航控制(miniGNC)類抗體蛋白及其製造和使用方法
JP2021510521A5 (https=)
JP2020533311A5 (ja) NKG2D、CD16およびNectin4に結合するタンパク質
RU2021110369A (ru) Белки, связывающие nkg2d, cd16 и опухолеассоциированный антиген
JP2018526981A5 (https=)
MX2011010159A (es) Anticuerpos multiespecificos que comprenden anticuerpos de longitud completa y fragmentos fab de cadena sencilla.
WO2010112194A1 (en) Antigen-binding polypeptides and multispecific antibodies comprising them
JP2021533159A5 (https=)
JP2022533538A5 (https=)
JP2024504390A5 (https=)
JP2023529842A5 (https=)
JP2023549537A5 (https=)
JP2023536461A5 (https=)
JP2024532489A5 (https=)
JP2020502233A5 (https=)
JP2023548529A5 (https=)
JP2023511376A5 (https=)
JP2025511288A (ja) 抗pvrig抗体、その医薬組成物及びその使用