JP2015537212A5 - - Google Patents

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Publication number
JP2015537212A5
JP2015537212A5 JP2015542849A JP2015542849A JP2015537212A5 JP 2015537212 A5 JP2015537212 A5 JP 2015537212A5 JP 2015542849 A JP2015542849 A JP 2015542849A JP 2015542849 A JP2015542849 A JP 2015542849A JP 2015537212 A5 JP2015537212 A5 JP 2015537212A5
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JP
Japan
Prior art keywords
gradient
polypeptide
contaminants
ionic strength
chromatography material
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015542849A
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English (en)
Japanese (ja)
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JP2015537212A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/070415 external-priority patent/WO2014078729A1/en
Publication of JP2015537212A publication Critical patent/JP2015537212A/ja
Publication of JP2015537212A5 publication Critical patent/JP2015537212A5/ja
Pending legal-status Critical Current

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JP2015542849A 2012-11-15 2013-11-15 イオン強度媒介のｐｈ勾配イオン交換クロマトグラフィー Pending JP2015537212A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261727051P 2012-11-15 2012-11-15
US61/727,051 2012-11-15
US201361780707P 2013-03-13 2013-03-13
US61/780,707 2013-03-13
PCT/US2013/070415 WO2014078729A1 (en) 2012-11-15 2013-11-15 IONIC STRENGTH-MEDIATED pH GRADIENT ION EXCHANGE CHROMATOGRAPHY

Publications (2)

Publication Number Publication Date
JP2015537212A JP2015537212A (ja) 2015-12-24
JP2015537212A5 true JP2015537212A5 (enExample) 2016-12-28

Family

ID=50731733

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015542849A Pending JP2015537212A (ja) 2012-11-15 2013-11-15 イオン強度媒介のｐｈ勾配イオン交換クロマトグラフィー

Country Status (11)

Country Link
US (2) US9810670B2 (enExample)
EP (1) EP2920586A4 (enExample)
JP (1) JP2015537212A (enExample)
KR (1) KR20150084046A (enExample)
CN (1) CN105051528A (enExample)
BR (1) BR112015011011A2 (enExample)
CA (1) CA2890979A1 (enExample)
HK (1) HK1217232A1 (enExample)
MX (1) MX2015006149A (enExample)
RU (1) RU2015122726A (enExample)
WO (1) WO2014078729A1 (enExample)

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TW202128264A (zh) * 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 使用經預測之溶離緩衝鹽濃度的陽離子層析法
CN111024883B (zh) * 2019-12-31 2022-12-06 上海博威生物医药有限公司 一种奥马珠单抗的电荷异质体的分离方法
CN111239278B (zh) * 2020-02-05 2022-11-04 康立泰生物医药(青岛)有限公司 一种检测重组人白介素-12蛋白电荷变异体的方法及应用
JP7686180B2 (ja) * 2020-04-17 2025-06-02 小野薬品工業株式会社 タンパク質製剤原薬の着色除去方法
KR102283871B1 (ko) * 2021-03-02 2021-08-02 한국원자력연구원 크로마토그래피를 이용한 무담체 홀뮴-166의 분리 방법, 분리 장치 및 이에 의하여 분리된 무담체 홀뮴-166
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CN114544839B (zh) * 2022-01-20 2024-08-20 未名生物医药有限公司 一种抗人神经生长因子抗体的电荷变异体检测方法
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