JP2015530971A5 - - Google Patents
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- JP2015530971A5 JP2015530971A5 JP2015520685A JP2015520685A JP2015530971A5 JP 2015530971 A5 JP2015530971 A5 JP 2015530971A5 JP 2015520685 A JP2015520685 A JP 2015520685A JP 2015520685 A JP2015520685 A JP 2015520685A JP 2015530971 A5 JP2015530971 A5 JP 2015530971A5
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- Prior art keywords
- seq
- tau
- amino acid
- antibody
- acid sequence
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- 102000004965 antibodies Human genes 0.000 claims 32
- 108090001123 antibodies Proteins 0.000 claims 32
- 125000003275 alpha amino acid group Chemical group 0.000 claims 21
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- 238000006467 substitution reaction Methods 0.000 claims 5
- 230000002776 aggregation Effects 0.000 claims 4
- 238000004220 aggregation Methods 0.000 claims 4
- 150000001413 amino acids Chemical group 0.000 claims 3
- 238000003018 immunoassay Methods 0.000 claims 3
- 229920001850 Nucleic acid sequence Polymers 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- 206010001897 Alzheimer's disease Diseases 0.000 claims 1
- 206010003591 Ataxia Diseases 0.000 claims 1
- 210000004556 Brain Anatomy 0.000 claims 1
- 210000003169 Central Nervous System Anatomy 0.000 claims 1
- 206010057668 Cognitive disease Diseases 0.000 claims 1
- 206010010904 Convulsion Diseases 0.000 claims 1
- 206010039911 Seizure Diseases 0.000 claims 1
- 230000002730 additional Effects 0.000 claims 1
- 230000003542 behavioural Effects 0.000 claims 1
- 238000004166 bioassay Methods 0.000 claims 1
- 108091006028 chimera Proteins 0.000 claims 1
- 230000004064 dysfunction Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000002996 emotional Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000012133 immunoprecipitate Substances 0.000 claims 1
- 230000001771 impaired Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 210000000653 nervous system Anatomy 0.000 claims 1
- 238000010899 nucleation Methods 0.000 claims 1
- 238000007910 systemic administration Methods 0.000 claims 1
- 230000000699 topical Effects 0.000 claims 1
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261667515P | 2012-07-03 | 2012-07-03 | |
US61/667,515 | 2012-07-03 | ||
US201261694989P | 2012-08-30 | 2012-08-30 | |
US61/694,989 | 2012-08-30 | ||
PCT/US2013/049333 WO2014008404A1 (en) | 2012-07-03 | 2013-07-03 | Antibodies to tau |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018098889A Division JP2018184398A (ja) | 2012-07-03 | 2018-05-23 | タウに対する抗体 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2015530971A JP2015530971A (ja) | 2015-10-29 |
JP2015530971A5 true JP2015530971A5 (US20080131398A1-20080605-C00009.png) | 2016-08-18 |
JP6345655B2 JP6345655B2 (ja) | 2018-06-20 |
Family
ID=49882495
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015520685A Expired - Fee Related JP6345655B2 (ja) | 2012-07-03 | 2013-07-03 | タウに対する抗体 |
JP2018098889A Pending JP2018184398A (ja) | 2012-07-03 | 2018-05-23 | タウに対する抗体 |
JP2020070416A Pending JP2020125310A (ja) | 2012-07-03 | 2020-04-09 | タウに対する抗体 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018098889A Pending JP2018184398A (ja) | 2012-07-03 | 2018-05-23 | タウに対する抗体 |
JP2020070416A Pending JP2020125310A (ja) | 2012-07-03 | 2020-04-09 | タウに対する抗体 |
Country Status (17)
Families Citing this family (51)
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JP6568514B2 (ja) | 2013-03-15 | 2019-08-28 | エーシー イミューン エス.エー. | 抗タウ抗体及び使用方法 |
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TWI664190B (zh) | 2014-06-27 | 2019-07-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
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2014
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2015
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2018
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