JP2015523362A5 - - Google Patents
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- JP2015523362A5 JP2015523362A5 JP2015520531A JP2015520531A JP2015523362A5 JP 2015523362 A5 JP2015523362 A5 JP 2015523362A5 JP 2015520531 A JP2015520531 A JP 2015520531A JP 2015520531 A JP2015520531 A JP 2015520531A JP 2015523362 A5 JP2015523362 A5 JP 2015523362A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- urolithin
- pharmaceutical composition
- disease
- food
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261665137P | 2012-06-27 | 2012-06-27 | |
| US61/665,137 | 2012-06-27 | ||
| US201261712886P | 2012-10-12 | 2012-10-12 | |
| US61/712,886 | 2012-10-12 | ||
| US201361791137P | 2013-03-15 | 2013-03-15 | |
| US61/791,137 | 2013-03-15 | ||
| PCT/US2013/048310 WO2014004902A2 (en) | 2012-06-27 | 2013-06-27 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018140453A Division JP6879980B2 (ja) | 2012-06-27 | 2018-07-26 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015523362A JP2015523362A (ja) | 2015-08-13 |
| JP2015523362A5 true JP2015523362A5 (cg-RX-API-DMAC7.html) | 2016-10-06 |
| JP6422163B2 JP6422163B2 (ja) | 2018-11-14 |
Family
ID=48782652
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015520531A Active JP6422163B2 (ja) | 2012-06-27 | 2013-06-27 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
| JP2018140453A Active JP6879980B2 (ja) | 2012-06-27 | 2018-07-26 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
| JP2021077856A Active JP7339296B2 (ja) | 2012-06-27 | 2021-04-30 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
| JP2023097670A Pending JP2023107934A (ja) | 2012-06-27 | 2023-06-14 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
| JP2025135511A Pending JP2025161884A (ja) | 2012-06-27 | 2025-08-15 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018140453A Active JP6879980B2 (ja) | 2012-06-27 | 2018-07-26 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
| JP2021077856A Active JP7339296B2 (ja) | 2012-06-27 | 2021-04-30 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
| JP2023097670A Pending JP2023107934A (ja) | 2012-06-27 | 2023-06-14 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
| JP2025135511A Pending JP2025161884A (ja) | 2012-06-27 | 2025-08-15 | ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長 |
Country Status (16)
| Country | Link |
|---|---|
| US (10) | US11020373B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP4566677A3 (cg-RX-API-DMAC7.html) |
| JP (5) | JP6422163B2 (cg-RX-API-DMAC7.html) |
| KR (4) | KR20210128511A (cg-RX-API-DMAC7.html) |
| CN (2) | CN110934863A (cg-RX-API-DMAC7.html) |
| AR (1) | AR091604A1 (cg-RX-API-DMAC7.html) |
| AU (6) | AU2013284419A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014032809A8 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2877718C (cg-RX-API-DMAC7.html) |
| DK (1) | DK4233858T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2968368T3 (cg-RX-API-DMAC7.html) |
| MX (3) | MX378354B (cg-RX-API-DMAC7.html) |
| PL (1) | PL4233858T3 (cg-RX-API-DMAC7.html) |
| PT (2) | PT2866804T (cg-RX-API-DMAC7.html) |
| SG (3) | SG10201610798QA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014004902A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210128511A (ko) * | 2012-06-27 | 2021-10-26 | 아마젠티스 에스에이 | 우롤리틴 또는 이의 전구체를 투여에 의한 자가포식 향상 또는 장수 증가 |
| AU2014206777A1 (en) * | 2013-01-18 | 2015-07-09 | Procell Sprl | Urolithin B for muscle growth |
| WO2015035391A1 (en) | 2013-09-09 | 2015-03-12 | Natreon, Inc. | Regulation of body weight gain by using dibenzo-alpha-pyrones |
| EP2862568A1 (en) * | 2013-10-15 | 2015-04-22 | Centre National de la Recherche Scientifique (CNRS) | Compositions comprising urolithins and uses thereof for the stimulation of insulin secretion |
| US9394269B2 (en) | 2013-12-23 | 2016-07-19 | Amazentis Sa | Process-scale synthesis of urolithins |
| GB201323008D0 (en) | 2013-12-24 | 2014-02-12 | Amazentis As | Compounds and uses thereof |
| GB201413228D0 (en) * | 2014-07-25 | 2014-09-10 | Nugerontix Ltd | Polyphenol compositions |
| CN107427488A (zh) * | 2014-12-19 | 2017-12-01 | 光环生命科学有限公司 | 鞣花酸二水合物在食品和保健品中的用途 |
| EP3284734B1 (en) | 2015-04-13 | 2021-12-01 | Sumitomo Seika Chemicals Co., Ltd. | Method for producing 2-halogenated benzoic acids |
| JP6740548B2 (ja) * | 2015-05-15 | 2020-08-19 | 公立大学法人岡山県立大学 | ウロリチン類を含有する育毛剤、及び、ウロリチン類を含有する5αレダクターゼ活性阻害剤 |
| JP2017014154A (ja) * | 2015-07-01 | 2017-01-19 | 公立大学法人岡山県立大学 | ウロリチン類を含有するヒアルロン酸産生促進剤 |
| JP6799767B2 (ja) * | 2015-07-07 | 2020-12-16 | 公立大学法人岡山県立大学 | ウロリチン類を含有するメラニン産生抑制剤 |
| GB201515391D0 (en) | 2015-08-28 | 2015-10-14 | Amazentis Sa | Compositions |
| WO2017109195A1 (en) * | 2015-12-24 | 2017-06-29 | Amazentis Sa | Compositions comprising nicotinamide riboside and a urolithin |
| JP6791478B2 (ja) * | 2016-05-26 | 2020-11-25 | 株式会社ダイセル | ウロリチン類を含有するアンジオテンシン変換酵素阻害剤 |
| JP2017210444A (ja) * | 2016-05-26 | 2017-11-30 | 株式会社ダイセル | ウロリチン類を含有するリパーゼ阻害剤 |
| US10981928B2 (en) * | 2016-06-29 | 2021-04-20 | Halo Life Science, Llc | Methods of making low odor choline salts of an organic compound |
| US10774328B2 (en) | 2016-07-11 | 2020-09-15 | University Of North Texas Health Science Center At Fort Worth | Treatment for glaucoma and other eye diseases |
| WO2018085419A1 (en) | 2016-11-01 | 2018-05-11 | Jian Feng | Method of producing naive pluripotent stem cells |
| EP3354645A1 (en) | 2017-01-26 | 2018-08-01 | Patheon Austria GmbH & Co KG | Process for preparing urolithins |
| EP3592425A1 (en) * | 2017-03-08 | 2020-01-15 | Amazentis SA | Methods for improving mitophagy in subjects |
| CA3055669A1 (en) | 2017-03-08 | 2018-09-13 | Amazentis Sa | Skin treatment methods |
| JP7761371B2 (ja) * | 2017-03-08 | 2025-10-28 | アマゼンティス エスアー | 対象におけるマイトファジーを改善するための方法 |
| JP2019097566A (ja) * | 2017-12-07 | 2019-06-24 | 大正製薬株式会社 | 体内時計調整用組成物 |
| JP7410025B2 (ja) * | 2017-12-20 | 2024-01-09 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | オートファジーの誘導のために高タンパク質を使用する組成物及び方法 |
| CN111479580B (zh) * | 2017-12-20 | 2024-08-06 | 雀巢产品有限公司 | 采用自噬诱发剂和高蛋白质的组合来诱发自噬的组合物和方法 |
| EP3755320A4 (en) * | 2018-02-19 | 2022-04-20 | Natreon, Inc. | SYNERGIC COMBINATIONS OF UROLITHINES A AND B TO IMPROVE COGNITIVE ABILITY OR FUNCTION |
| WO2019163437A1 (ja) | 2018-02-21 | 2019-08-29 | 株式会社ダイセル | ウロリチン類を含有する破骨細胞分化抑制剤 |
| IL313537A (en) * | 2018-02-27 | 2024-08-01 | Amazentis Sa | Urolitin A synthesis process |
| JP7217542B2 (ja) * | 2018-03-29 | 2023-02-03 | 国立大学法人 琉球大学 | 分化コントロール化合物を用いて造腫瘍性をもつおそれのある未分化iPS細胞等の混入を除去する方法 |
| JP7557374B2 (ja) * | 2018-04-30 | 2024-09-27 | アマゼンティス エスアー | 免疫増強剤としてのウロリチンa |
| CA3100335A1 (en) | 2018-05-15 | 2019-11-21 | University Of Louisville Research Foundation, Inc. | Urolithin a and derivatives thereof for use in therapy |
| WO2019236765A1 (en) * | 2018-06-05 | 2019-12-12 | Flagship Pioneering Innovations V, Inc. | Acylated catechin polyphenols and methods of their use for the treatment of cancer |
| EP3801496A4 (en) | 2018-06-05 | 2022-07-06 | Flagship Pioneering Innovations V, Inc. | ACTIVE AGENTS AND METHODS OF USE THEREOF FOR TREATING METABOLIC DISORDERS AND NAFLD |
| CN108676013B (zh) * | 2018-06-25 | 2021-01-01 | 中国医学科学院医药生物技术研究所 | 具有自噬激活活性的黄醇酮类化合物、其制备方法及其制药应用 |
| CN109316478A (zh) * | 2018-11-06 | 2019-02-12 | 上海出入境检验检疫局动植物与食品检验检疫技术中心 | 一种尿石素a在制备抗衰老的药物、化妆品中的应用及药物、化妆品 |
| PL245399B1 (pl) | 2018-11-29 | 2024-07-15 | Univ Warszawski Medyczny | Kompozycja farmaceutyczna zawierająca urolitynę A lub jej pochodną do zastosowania zewnętrznego miejscowego w leczeniu, hamowaniu i zapobieganiu chorobom skóry i błon śluzowych o podłożu zapalnym |
| EP3911312A1 (en) * | 2019-01-18 | 2021-11-24 | Société des Produits Nestlé S.A. | Agents and methods for increasing stem cell function |
| CN110066284B (zh) * | 2019-02-01 | 2021-06-04 | 贵阳倍隆生物科技有限公司 | 一种一锅法合成鞣花酸的方法 |
| CN110229167B (zh) * | 2019-05-22 | 2020-11-24 | 珠海萱嘉君行健康产业发展有限公司 | 一种利用五倍子制备鞣花酸的方法、制得的鞣花酸及其应用 |
| CN111995610A (zh) * | 2019-05-27 | 2020-11-27 | 首都医科大学 | 一种尿石素类化合物用于治疗胶质母细胞瘤药物的应用 |
| WO2020257283A1 (en) * | 2019-06-18 | 2020-12-24 | Mitopower Llc | Nicotinyl riboside compounds and their uses |
| US20220184015A1 (en) * | 2019-06-20 | 2022-06-16 | Societe Des Produits Nestle S.A. | Compositions and methods to potentiate musculoskeletal effect of one or more anabolic amino acids on bone health |
| GB201912107D0 (en) | 2019-08-22 | 2019-10-09 | Amazentis Sa | Combination |
| GB201915191D0 (en) | 2019-10-21 | 2019-12-04 | Floratek Gmbh | Novel heterocyclic compounds |
| GB201916046D0 (en) | 2019-11-04 | 2019-12-18 | Amazentis Sa | Diagnostic method |
| CN114760996A (zh) * | 2019-11-27 | 2022-07-15 | 雀巢产品有限公司 | 与间接ampk活化剂化合物组合的直接ampk活化剂化合物、组合物、方法和其用途 |
| WO2021105073A1 (en) * | 2019-11-27 | 2021-06-03 | Société des Produits Nestlé S.A. | Benzocoumarin ampk activator compounds, compositions, methods and uses thereof |
| CN113018305A (zh) * | 2019-12-24 | 2021-06-25 | 兰州大学 | 一种化合物在制备治疗阿尔兹海默症药物中的应用 |
| US20230075822A1 (en) * | 2020-02-20 | 2023-03-09 | The Royal Institution For The Advancement Of Learning/Mcgill University | Use of castalagin or analogs thereof for anti-cancer efficacy and to increase the response to immune checkpoint inhibitors |
| US20240000753A1 (en) * | 2020-07-17 | 2024-01-04 | The Trustees Of Columbia University In The City Of New York | Methods and compositions to increase lifespan and healthspan by mimicking the effects of time-restricted feeding |
| CN111983058B (zh) * | 2020-07-30 | 2023-06-23 | 云南中医药大学 | 中药抗非酒精性脂肪肝活性物质的筛选方法 |
| WO2022051643A1 (en) * | 2020-09-04 | 2022-03-10 | Natreon, Inc. | Methods of treating and preventing hepatotoxicity |
| CA3188397A1 (en) | 2020-09-25 | 2022-03-31 | Anupama Dattatreya | Compositions and methods using xanthan gum to stabilize at least one urolithin in an aqueous matrix |
| KR102623664B1 (ko) | 2020-12-10 | 2024-01-12 | 서울대학교산학협력단 | 유로리틴 a를 이용한 당뇨성 알츠하이머병의 치료 조성물 및 치료 방법 |
| CA3206062A1 (en) | 2021-01-27 | 2022-08-04 | Said Oumouch | Urolithin derivatives and methods of use thereof |
| CN112716938A (zh) * | 2021-02-25 | 2021-04-30 | 新疆医科大学 | 鞣花酸在制备缓解眼组织病变的药物中的用途 |
| KR102677423B1 (ko) * | 2021-09-17 | 2024-06-21 | 조선대학교산학협력단 | 망기페린을 포함하는 자가포식 활성화용 조성물 |
| KR102690860B1 (ko) * | 2021-10-13 | 2024-08-05 | 한국해양과학기술원 | 남극 진균 균주 Pleosporales sp. SF-7343 유래 대사화합물을 포함하는 염증질환 예방 또는 치료용 조성물 |
| WO2023073079A1 (en) * | 2021-10-28 | 2023-05-04 | Société des Produits Nestlé S.A. | Compositions and methods using a combination of nutrients to support cognition and emotional health in a mammal |
| EP4482947A1 (en) | 2022-02-24 | 2025-01-01 | Amazentis SA | Uses of urolithins |
| US20230301890A1 (en) | 2022-03-22 | 2023-09-28 | Amazentis Sa | Compositions comprising urolithins |
| CA3258478A1 (en) * | 2022-06-06 | 2023-12-14 | Amazentis Sa | Urolithines to improve heart function and health |
| CN119947717A (zh) * | 2022-07-27 | 2025-05-06 | 范徳利亚股份公司 | 尿石素衍生物的治疗用途 |
| CN115433151A (zh) * | 2022-09-02 | 2022-12-06 | 苏州大学 | 一种6,7,8-三羟基香豆素的制备方法 |
| CN115581689B (zh) * | 2022-10-17 | 2024-05-14 | 常州大学 | 尿石素b酰胺类衍生物的应用 |
| GB202219317D0 (en) | 2022-12-20 | 2023-02-01 | Amazentis Sa | Methods for improving mitophagy in subjects |
| GB202308224D0 (en) | 2023-06-01 | 2023-07-19 | Amazentis Sa | Formulation |
| CN116966188A (zh) * | 2023-07-14 | 2023-10-31 | 天津医科大学总医院 | 丁香素在制备治疗和/或预防炎症性肠病药物中的应用 |
| GB202312220D0 (en) | 2023-08-09 | 2023-09-20 | Amazentis Sa | Formulation |
| WO2025076497A1 (en) * | 2023-10-06 | 2025-04-10 | Northeast Ohio Medical University | Combination treatment of tau pathology |
| FR3153998A1 (fr) * | 2023-10-13 | 2025-04-18 | L'oreal | Utilisation cosmétique d’iso-urolithine A sur une peau sensible |
| FR3153997A1 (fr) * | 2023-10-13 | 2025-04-18 | L'oreal | Utilisation cosmétique d'au moins l’urolithine B sur une peau sensible |
| FR3153996A1 (fr) * | 2023-10-13 | 2025-04-18 | L'oreal | Utilisation cosmétique d'au moins l’urolithine C sur une peau sensible |
| WO2025078645A1 (en) * | 2023-10-13 | 2025-04-17 | L'oreal | Cosmetic use of at least urolithin b or c on a sensitive skin |
| GB202316295D0 (en) | 2023-10-24 | 2023-12-06 | Amazentis Sa | Composition |
| GB202319994D0 (en) | 2023-12-22 | 2024-02-07 | Amazentis Sa | Compositions for use |
| CN117771237B (zh) * | 2024-02-27 | 2024-05-03 | 南昌医学院 | 一种松香烷型二萜化合物的用途和制备方法 |
| WO2025194036A1 (en) * | 2024-03-14 | 2025-09-18 | Washington University | Autophagy enhancers |
| WO2025224366A1 (en) | 2024-04-26 | 2025-10-30 | Amazentis Sa | Immune health improvers |
| WO2025252771A1 (en) | 2024-06-03 | 2025-12-11 | Amazentis Sa | Urolithin combinations |
| CN119792272B (zh) * | 2025-02-07 | 2025-10-03 | 陕西中鸿科瑞再生医学研究院有限公司 | 一种改善睡眠的组合物及其制备方法与制剂 |
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| ES3026991T3 (en) | 2010-12-23 | 2025-06-12 | Amazentis Sa | Non-therapeutic method of increasing or maintaining mitochondrial function |
| WO2012113835A1 (en) | 2011-02-22 | 2012-08-30 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | C-glucosidic ellagitannin compounds for use for altering the supramolecular arrangement of actin and for the treatment of osteoporosis, cancer, bacterial infection and viral infection |
| KR20210128511A (ko) | 2012-06-27 | 2021-10-26 | 아마젠티스 에스에이 | 우롤리틴 또는 이의 전구체를 투여에 의한 자가포식 향상 또는 장수 증가 |
| WO2017109195A1 (en) | 2015-12-24 | 2017-06-29 | Amazentis Sa | Compositions comprising nicotinamide riboside and a urolithin |
-
2013
- 2013-06-27 KR KR1020217033621A patent/KR20210128511A/ko not_active Ceased
- 2013-06-27 PT PT137355434T patent/PT2866804T/pt unknown
- 2013-06-27 SG SG10201610798QA patent/SG10201610798QA/en unknown
- 2013-06-27 EP EP25157187.3A patent/EP4566677A3/en active Pending
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