MX2020011619A - Urolitina como mejorador inmunitario. - Google Patents
Urolitina como mejorador inmunitario.Info
- Publication number
- MX2020011619A MX2020011619A MX2020011619A MX2020011619A MX2020011619A MX 2020011619 A MX2020011619 A MX 2020011619A MX 2020011619 A MX2020011619 A MX 2020011619A MX 2020011619 A MX2020011619 A MX 2020011619A MX 2020011619 A MX2020011619 A MX 2020011619A
- Authority
- MX
- Mexico
- Prior art keywords
- stem cell
- urolithins
- immune
- relates
- urolithin
- Prior art date
Links
- 239000003623 enhancer Substances 0.000 title abstract 4
- 229930186301 urolithin Natural products 0.000 title abstract 4
- 210000000130 stem cell Anatomy 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000002708 enhancing effect Effects 0.000 abstract 2
- 230000028993 immune response Effects 0.000 abstract 2
- 230000001737 promoting effect Effects 0.000 abstract 2
- 230000003190 augmentative effect Effects 0.000 abstract 1
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 230000003915 cell function Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente invención se refiere a compuestos para usar a fin de generar una respuesta inmunitaria a un antígeno y/o mejorar, modular o aumentar una respuesta inmunitaria a un antígeno. Particularmente el uso de urolitinas. La invención también se refiere a mejoradores inmunitarios que comprenden urolitinas, métodos para usar tales mejoradores inmunitarios y procesos para la preparación de tales mejoradores inmunitarios. La invención también se refiere al uso de urolitinas en métodos para modular la función de las células madre, por ejemplo, mejorar la cantidad de células madre, promover la regeneración de las células madre y promover la diferenciación de las células madre.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1807051.6A GB201807051D0 (en) | 2018-04-30 | 2018-04-30 | Biological enhancer |
GBGB1807819.6A GB201807819D0 (en) | 2018-05-14 | 2018-05-14 | Biological enhancer |
PCT/EP2019/061093 WO2019211294A1 (en) | 2018-04-30 | 2019-04-30 | Urolithin a as immune enhancer |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020011619A true MX2020011619A (es) | 2021-01-15 |
Family
ID=66379918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020011619A MX2020011619A (es) | 2018-04-30 | 2019-04-30 | Urolitina como mejorador inmunitario. |
Country Status (7)
Country | Link |
---|---|
US (3) | US10792276B2 (es) |
EP (1) | EP3787615A1 (es) |
JP (1) | JP2021522296A (es) |
CN (1) | CN112512517A (es) |
BR (1) | BR112020022159A2 (es) |
MX (1) | MX2020011619A (es) |
WO (1) | WO2019211294A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2020011619A (es) | 2018-04-30 | 2021-01-15 | Amazentis Sa | Urolitina como mejorador inmunitario. |
US20240000747A1 (en) * | 2020-11-26 | 2024-01-04 | Daicel Corporation | Sirtuin 6 activator |
AU2022212883A1 (en) | 2021-01-27 | 2023-08-17 | Vandria Sa | Urolithin derivatives and methods of use thereof |
JP2024516187A (ja) * | 2021-05-05 | 2024-04-12 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 幹細胞機能を向上させるためのウロリチン |
CN113813255B (zh) * | 2021-10-20 | 2023-09-01 | 山东大学 | 尿石素a及其衍生物在肿瘤免疫治疗的应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2646177T3 (es) | 2006-04-26 | 2017-12-12 | The Regents Of The University Of California | Usos terapéuticos de las urolitinas |
PT2866804T (pt) | 2012-06-27 | 2023-12-18 | Amazentis Sa | Melhoria da autofagia ou aumento da longevidade por administração de urolitinas ou seus precursores |
EP3087065B1 (en) | 2013-12-23 | 2020-01-22 | Amazentis SA | Synthesis of urolithins |
WO2016099947A1 (en) * | 2014-12-19 | 2016-06-23 | Halo Life Science, Llc | Use of ellagic acid dihydrate in food products and nutraceuticals |
US20170304263A1 (en) * | 2016-04-20 | 2017-10-26 | John Michael Pezzuto | Antioxidative stress compositions, methods of preparing and uses thereof |
MX2020011619A (es) | 2018-04-30 | 2021-01-15 | Amazentis Sa | Urolitina como mejorador inmunitario. |
-
2019
- 2019-04-30 MX MX2020011619A patent/MX2020011619A/es unknown
- 2019-04-30 US US16/398,956 patent/US10792276B2/en active Active
- 2019-04-30 EP EP19721270.7A patent/EP3787615A1/en active Pending
- 2019-04-30 BR BR112020022159-7A patent/BR112020022159A2/pt unknown
- 2019-04-30 CN CN201980044615.5A patent/CN112512517A/zh active Pending
- 2019-04-30 JP JP2020561032A patent/JP2021522296A/ja active Pending
- 2019-04-30 WO PCT/EP2019/061093 patent/WO2019211294A1/en unknown
-
2020
- 2020-10-01 US US17/061,265 patent/US11426380B2/en active Active
-
2022
- 2022-08-24 US US17/822,027 patent/US20230097072A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20230097072A1 (en) | 2023-03-30 |
BR112020022159A2 (pt) | 2021-01-26 |
WO2019211294A1 (en) | 2019-11-07 |
US10792276B2 (en) | 2020-10-06 |
US11426380B2 (en) | 2022-08-30 |
US20190328703A1 (en) | 2019-10-31 |
JP2021522296A (ja) | 2021-08-30 |
CN112512517A (zh) | 2021-03-16 |
EP3787615A1 (en) | 2021-03-10 |
US20210085642A1 (en) | 2021-03-25 |
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