JP2015520758A5 - - Google Patents
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- JP2015520758A5 JP2015520758A5 JP2015512801A JP2015512801A JP2015520758A5 JP 2015520758 A5 JP2015520758 A5 JP 2015520758A5 JP 2015512801 A JP2015512801 A JP 2015512801A JP 2015512801 A JP2015512801 A JP 2015512801A JP 2015520758 A5 JP2015520758 A5 JP 2015520758A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- heavy chain
- antibody
- variable region
- light chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261649110P | 2012-05-18 | 2012-05-18 | |
| US61/649,110 | 2012-05-18 | ||
| US13/804,227 | 2013-03-14 | ||
| US13/804,227 US20130309223A1 (en) | 2012-05-18 | 2013-03-14 | CD33 Antibodies And Use Of Same To Treat Cancer |
| PCT/US2013/041209 WO2013173496A2 (en) | 2012-05-18 | 2013-05-15 | Cd33 antibodies and use of same to treat cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015520758A JP2015520758A (ja) | 2015-07-23 |
| JP2015520758A5 true JP2015520758A5 (https=) | 2016-05-19 |
| JP6454269B2 JP6454269B2 (ja) | 2019-01-16 |
Family
ID=49581477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512801A Expired - Fee Related JP6454269B2 (ja) | 2012-05-18 | 2013-05-15 | Ｃｄ３３抗体及び癌を処置するためのその使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US20130309223A1 (https=) |
| EP (2) | EP2850104B1 (https=) |
| JP (1) | JP6454269B2 (https=) |
| KR (2) | KR102100467B1 (https=) |
| CN (1) | CN104936617B (https=) |
| AU (3) | AU2013262788B2 (https=) |
| CA (1) | CA2873286C (https=) |
| DK (1) | DK2850104T3 (https=) |
| EA (1) | EA029987B1 (https=) |
| ES (1) | ES2686618T3 (https=) |
| IL (1) | IL235733B (https=) |
| IN (1) | IN2014DN10653A (https=) |
| MX (1) | MX350808B (https=) |
| NZ (1) | NZ702748A (https=) |
| SG (1) | SG11201407610WA (https=) |
| TW (1) | TWI593707B (https=) |
| WO (1) | WO2013173496A2 (https=) |
| ZA (1) | ZA201409224B (https=) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008070593A2 (en) | 2006-12-01 | 2008-06-12 | Seattle Genetics, Inc. | Variant target binding agents and uses thereof |
| US20130309223A1 (en) | 2012-05-18 | 2013-11-21 | Seattle Genetics, Inc. | CD33 Antibodies And Use Of Same To Treat Cancer |
| ES2826398T3 (es) | 2013-10-15 | 2021-05-18 | Seagen Inc | Enlazadores-fármacos pegilados para una mejor farmacocinética de los conjugados ligando-fármaco |
| WO2015077605A1 (en) * | 2013-11-25 | 2015-05-28 | Seattle Genetics, Inc. | Preparing antibodies from cho cell cultures for conjugation |
| EA201691214A1 (ru) * | 2013-12-13 | 2016-12-30 | Дженентек, Инк. | Антитела к cd33 и иммуноконъюгаты |
| KR20230088389A (ko) | 2014-02-11 | 2023-06-19 | 씨젠 인크. | 단백질의 선택적 환원 |
| SG10202001468UA (en) | 2014-02-17 | 2020-04-29 | Seattle Genetics Inc | Hydrophilic antibody-drug conjugates |
| EP3126390B2 (en) * | 2014-04-03 | 2026-01-07 | Cellectis | Cd33 specific chimeric antigen receptors for cancer immunotherapy |
| SG10201913765YA (en) * | 2014-07-21 | 2020-03-30 | Novartis Ag | Treatment of cancer using a cd33 chimeric antigen receptor |
| ES2869972T3 (es) | 2015-01-26 | 2021-10-26 | Cellectis | Sistemas de receptores de antígenos quiméricos dirigidos por mAb para clasificar/agotar células inmunitarias genomanipuladas |
| JP7376977B2 (ja) | 2015-06-12 | 2023-11-09 | アレクトル エルエルシー | 抗ｃｄ３３抗体及びその使用方法 |
| TW201709932A (zh) | 2015-06-12 | 2017-03-16 | 西雅圖遺傳學公司 | Ｃｄ１２３抗體及其共軛物 |
| JP7497953B2 (ja) | 2015-06-12 | 2024-06-11 | アレクトル エルエルシー | 抗ｃｄ３３抗体及びその使用方法 |
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| CN110352068A (zh) | 2016-12-02 | 2019-10-18 | 南加利福尼亚大学 | 合成的免疫受体及其使用方法 |
| JP7337698B2 (ja) | 2017-02-28 | 2023-09-04 | シージェン インコーポレイテッド | コンジュゲート化のためのシステイン突然変異抗体 |
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| IL301637B2 (en) | 2017-09-29 | 2024-10-01 | Daiichi Sankyo Co Ltd | Antibody-pyrrolobenzodiazepine derivative conjugate |
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| EP3849565A4 (en) | 2018-09-12 | 2022-12-28 | Fred Hutchinson Cancer Research Center | REDUCTION OF CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS |
| EP3856242A4 (en) * | 2018-09-25 | 2022-05-18 | Academia Sinica | ANTI-SIGLEC ANTIBODIES, PHARMACEUTICAL COMPOSITION THEREOF AND USES THEREOF |
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| AU2020225631A1 (en) | 2019-02-22 | 2021-09-16 | Memorial Sloan Kettering Cancer Center | CD33 antibodies and methods of using the same to treat cancer |
| EP3950061A4 (en) | 2019-03-25 | 2022-11-16 | Daiichi Sankyo Company, Limited | ANTIBODY PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE |
| AU2020246448A1 (en) | 2019-03-25 | 2021-10-14 | Daiichi Sankyo Company, Limited | Anti-HER2 antibody-pyrrolobenzodiazepine derivative conjugate |
| TWI841715B (zh) | 2019-03-27 | 2024-05-11 | 日商第一三共股份有限公司 | 抗體-吡咯并苯二氮呯衍生物結合物及ｐａｒｐ抑制劑之組合及其用途 |
| EP3962527A4 (en) | 2019-04-30 | 2023-11-01 | Senti Biosciences, Inc. | CHIMERIC RECEPTORS AND METHODS OF USE THEREOF |
| AU2020287378A1 (en) * | 2019-06-06 | 2022-02-03 | Mythic Therapeutics, Inc. | Antigen-binding protein constructs and uses thereof |
| WO2021138407A2 (en) | 2020-01-03 | 2021-07-08 | Marengo Therapeutics, Inc. | Multifunctional molecules that bind to cd33 and uses thereof |
| CA3173205A1 (en) * | 2020-03-31 | 2021-10-07 | Roland B. WALTER | Human anti-cd33 antibodies and uses thereof |
| WO2021207701A1 (en) | 2020-04-10 | 2021-10-14 | Seagen Inc. | Charge variant linkers |
| US20210402001A1 (en) * | 2020-06-30 | 2021-12-30 | David I. Cohen | Zinc Porters, and their Monoclonal Antibody Conjugates, for the Prevention and Treatment of COVID-19 (SARS-CoV-2), Other Infections, and Cancers |
| TW202227479A (zh) | 2020-09-02 | 2022-07-16 | 日商第一三共股份有限公司 | 新穎內－β－Ｎ－乙醯葡萄糖胺苷酶 |
| CA3201419A1 (en) * | 2020-11-11 | 2022-05-19 | Versapeutics Inc. | Antibody variants against wnt receptor ryk |
| CA3204628A1 (en) | 2021-01-13 | 2022-07-21 | John T. POIRIER | Antibody-pyrrolobenzodiazepine derivative conjugate |
| CN117062611A (zh) | 2021-01-26 | 2023-11-14 | 惠和生物技术(上海)有限公司 | 嵌合抗原受体（car）构建体和表达car构建体的nk细胞 |
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| AU2022262600A1 (en) | 2021-04-20 | 2023-10-05 | Seagen Inc. | Modulation of antibody-dependent cellular cytotoxicity |
| CA3221398A1 (en) | 2021-05-28 | 2022-12-01 | Seagen Inc. | Anthracycline antibody conjugates |
| IL312728A (en) | 2021-11-30 | 2024-07-01 | Daiichi Sankyo Co Ltd | Protease-cleavable masked antibodies |
| US20250170255A1 (en) | 2022-02-09 | 2025-05-29 | Daiichi Sankyo Company, Limited | Environmentally-responsive masked antibody and use thereof |
| US20250207169A1 (en) | 2022-03-02 | 2025-06-26 | Daiichi Sankyo Company, Limited | METHOD FOR PRODUCING Fc-CONTAINING MOLECULE |
| IL315508A (en) | 2022-03-17 | 2024-11-01 | Seagen Inc | Camptothecin conjugates |
| WO2024129756A1 (en) | 2022-12-13 | 2024-06-20 | Seagen Inc. | Site-specific engineered cysteine antibody drug conjugates |
| CN116375874B (zh) * | 2023-04-14 | 2023-12-26 | 上海精翰生物科技有限公司 | 一种cd33抗体及其应用 |
| WO2025090774A1 (en) | 2023-10-24 | 2025-05-01 | Seagen Inc. | Chemotherapeutic compounds and methods of use |
| WO2025149947A1 (en) | 2024-01-12 | 2025-07-17 | Seagen Inc. | Antibody-drug conjugates |
| WO2025174974A1 (en) * | 2024-02-14 | 2025-08-21 | Bristol-Myers Squibb Company | Anti-cd33 antibodies and uses thereof |
| CN121673409A (zh) * | 2024-09-12 | 2026-03-17 | 安诺柏德生物医药科技(苏州)有限公司 | 靶向人cd33的人源化抗体及其应用 |
| CN119080935B (zh) * | 2024-10-11 | 2026-04-14 | 上海市同仁医院 | 一种抗人SMIM45-107aa单克隆抗体及其用途 |
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-
2013
- 2013-03-14 US US13/804,227 patent/US20130309223A1/en not_active Abandoned
- 2013-05-15 SG SG11201407610WA patent/SG11201407610WA/en unknown
- 2013-05-15 EP EP13790467.8A patent/EP2850104B1/en active Active
- 2013-05-15 EA EA201492137A patent/EA029987B1/ru unknown
- 2013-05-15 NZ NZ702748A patent/NZ702748A/en not_active IP Right Cessation
- 2013-05-15 MX MX2014013866A patent/MX350808B/es active IP Right Grant
- 2013-05-15 EP EP18171884.2A patent/EP3421048A1/en not_active Withdrawn
- 2013-05-15 IN IN10653DEN2014 patent/IN2014DN10653A/en unknown
- 2013-05-15 CA CA2873286A patent/CA2873286C/en active Active
- 2013-05-15 WO PCT/US2013/041209 patent/WO2013173496A2/en not_active Ceased
- 2013-05-15 US US14/401,837 patent/US9587019B2/en active Active
- 2013-05-15 JP JP2015512801A patent/JP6454269B2/ja not_active Expired - Fee Related
- 2013-05-15 AU AU2013262788A patent/AU2013262788B2/en not_active Ceased
- 2013-05-15 ES ES13790467.8T patent/ES2686618T3/es active Active
- 2013-05-15 CN CN201380026079.9A patent/CN104936617B/zh active Active
- 2013-05-15 KR KR1020147035516A patent/KR102100467B1/ko not_active Expired - Fee Related
- 2013-05-15 KR KR1020207010113A patent/KR102241478B1/ko not_active Expired - Fee Related
- 2013-05-15 DK DK13790467.8T patent/DK2850104T3/en active
- 2013-05-17 TW TW102117539A patent/TWI593707B/zh active
-
2014
- 2014-11-17 IL IL235733A patent/IL235733B/en unknown
- 2014-12-15 ZA ZA2014/09224A patent/ZA201409224B/en unknown
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2017
- 2017-01-20 US US15/411,947 patent/US10787514B2/en active Active
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2018
- 2018-05-17 AU AU2018203508A patent/AU2018203508C1/en not_active Ceased
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2020
- 2020-05-22 AU AU2020203365A patent/AU2020203365B2/en not_active Ceased
- 2020-07-29 US US16/942,647 patent/US20210047404A1/en not_active Abandoned
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