JP2015520752A - Ｎａｍｐｔ阻害薬としてのピリダジンおよびピリジン誘導体 - Google Patents

Ｎａｍｐｔ阻害薬としてのピリダジンおよびピリジン誘導体 Download PDF

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JP2015520752A
JP2015520752A JP2015511730A JP2015511730A JP2015520752A JP 2015520752 A JP2015520752 A JP 2015520752A JP 2015511730 A JP2015511730 A JP 2015511730A JP 2015511730 A JP2015511730 A JP 2015511730A JP 2015520752 A JP2015520752 A JP 2015520752A
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carboxamide
phenyl
pyridazin
azetidine
piperidin
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JP2015520752A5 (enExample
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ハンセン，トッド・エム
ロングネッカー，ケントン
ヘイマン，ハワード・アール
カーティン，マイケル・エル
クラーク，リチャード・エフ
ソーレンセン，ブライアン
ジー，ジーチン
ドハーティ，ジョージ
フレイ，ロビン
ウォーラー，ケビン
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アッヴィ・インコーポレイテッド
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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Public Health (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • AIDS & HIV (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
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JP2015511730A 2012-05-11 2013-05-10 Ｎａｍｐｔ阻害薬としてのピリダジンおよびピリジン誘導体 Pending JP2015520752A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261645692P 2012-05-11 2012-05-11
US61/645,692 2012-05-11
US201261719013P 2012-10-26 2012-10-26
US61/719,013 2012-10-26
US201361779756P 2013-03-13 2013-03-13
US61/779,756 2013-03-13
PCT/US2013/040481 WO2013170115A1 (en) 2012-05-11 2013-05-10 Pyridazine and pyridine derivatives as nampt inhibitors

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Publication Number Publication Date
JP2015520752A true JP2015520752A (ja) 2015-07-23
JP2015520752A5 JP2015520752A5 (enExample) 2016-06-30

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JP2015511730A Pending JP2015520752A (ja) 2012-05-11 2013-05-10 Ｎａｍｐｔ阻害薬としてのピリダジンおよびピリジン誘導体

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US (4) US8975398B2 (enExample)
EP (1) EP2847181A1 (enExample)
JP (1) JP2015520752A (enExample)
CN (1) CN104583194A (enExample)
AR (1) AR091023A1 (enExample)
CA (1) CA2873097A1 (enExample)
HK (1) HK1209739A1 (enExample)
MX (1) MX2014013751A (enExample)
TW (1) TW201350478A (enExample)
UY (1) UY34804A (enExample)
WO (1) WO2013170115A1 (enExample)

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JP2019521114A (ja) 2016-06-08 2019-07-25 アッヴィ・インコーポレイテッド 抗ｅｇｆｒ抗体薬物コンジュゲート
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MA46660A (fr) 2016-10-18 2019-08-28 Seattle Genetics Inc Administration ciblée d'inhibiteurs de la voie de récupération de nicotinamide adénine dinucléotide
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