|
US4714681A
(en)
|
1981-07-01 |
1987-12-22 |
The Board Of Reagents, The University Of Texas System Cancer Center |
Quadroma cells and trioma cells and methods for the production of same
|
|
US4474893A
(en)
|
1981-07-01 |
1984-10-02 |
The University of Texas System Cancer Center |
Recombinant monoclonal antibodies
|
|
NZ201918A
(en)
|
1981-09-18 |
1987-04-30 |
Genentech Inc |
N-terminal methionyl analogues of bovine growth hormone
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4873192A
(en)
|
1987-02-17 |
1989-10-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
Process for site specific mutagenesis without phenotypic selection
|
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
WO1989012624A2
(en)
|
1988-06-14 |
1989-12-28 |
Cetus Corporation |
Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom
|
|
US4925648A
(en)
|
1988-07-29 |
1990-05-15 |
Immunomedics, Inc. |
Detection and treatment of infectious and inflammatory lesions
|
|
US5601819A
(en)
|
1988-08-11 |
1997-02-11 |
The General Hospital Corporation |
Bispecific antibodies for selective immune regulation and for selective immune cell binding
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
US5225538A
(en)
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
|
IE63847B1
(en)
|
1989-05-05 |
1995-06-14 |
Res Dev Foundation |
A novel antibody delivery system for biological response modifiers
|
|
EP0739904A1
(en)
|
1989-06-29 |
1996-10-30 |
Medarex, Inc. |
Bispecific reagents for aids therapy
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
EP1690935A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US5314995A
(en)
|
1990-01-22 |
1994-05-24 |
Oncogen |
Therapeutic interleukin-2-antibody based fusion proteins
|
|
DE69127749T2
(de)
|
1990-03-20 |
1998-04-16 |
The Trustees Of Columbia University In The City Of New York, New York, N.Y. |
Chimäre antikörper mit rezeptor-bindenden liganden anstelle ihrer konstanten region
|
|
DK0553244T4
(da)
|
1990-10-05 |
2005-08-01 |
Celldex Therapeutics Inc |
Målrettet immunostimulering med bispecifikke reagenser
|
|
AU8727291A
(en)
|
1990-10-29 |
1992-06-11 |
Cetus Oncology Corporation |
Bispecific antibodies, method of production, and uses thereof
|
|
ATE218889T1
(de)
|
1990-11-09 |
2002-06-15 |
Stephen D Gillies |
Cytokine immunokonjugate
|
|
EP0582595A1
(en)
|
1991-04-26 |
1994-02-16 |
Surface Active Limited |
Novel antibodies, and methods for their use
|
|
FR2686087A1
(fr)
|
1992-01-13 |
1993-07-16 |
Inst Nat Sante Rech Med |
Nouvel antigene lymphocytaire, anticorps correspondant et leurs applications.
|
|
EP1306095A3
(en)
|
1992-03-05 |
2003-06-25 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
US5633149A
(en)
|
1994-12-07 |
1997-05-27 |
Incyte Pharmaceuticals, Inc. |
Polynucleotide encoding novel chemokine expressed in inflamed adenoid
|
|
US6692920B1
(en)
|
1994-12-07 |
2004-02-17 |
Incyte Corporation |
Antibodies to a chemokine expressed in inflamed adenoid
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
CN1190991A
(zh)
|
1995-06-05 |
1998-08-19 |
人类基因组科学公司 |
人类趋化因子β-11和人类趋化因子α-1
|
|
WO1998011226A2
(en)
|
1996-09-10 |
1998-03-19 |
Schering Corporation |
Mammalian chemokines, related reagents
|
|
US6852508B1
(en)
|
1997-02-28 |
2005-02-08 |
Genetics Institute, Llc |
Chemokine with amino-terminal modifications
|
|
US20030207346A1
(en)
|
1997-05-02 |
2003-11-06 |
William R. Arathoon |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6110695A
(en)
|
1997-12-02 |
2000-08-29 |
The Regents Of The University Of California |
Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US6897044B1
(en)
|
1999-01-28 |
2005-05-24 |
Biogen Idec, Inc. |
Production of tetravalent antibodies
|
|
US6723538B2
(en)
|
1999-03-11 |
2004-04-20 |
Micromet Ag |
Bispecific antibody and chemokine receptor constructs
|
|
US6849425B1
(en)
|
1999-10-14 |
2005-02-01 |
Ixsys, Inc. |
Methods of optimizing antibody variable region binding affinity
|
|
US20030186889A1
(en)
|
2000-03-31 |
2003-10-02 |
Wolf-Georg Forssmann |
Diagnostic and medicament for analysing the cell surface proteome of tumour and inflammatory cells and for treating tumorous and inflammatory diseases, preferably using a specific chemokine receptor analysis and the chemokine receptor-ligand interaction
|
|
GB2361003A
(en)
|
2000-04-07 |
2001-10-10 |
Astrazeneca Ab |
Novel compounds
|
|
US7052676B2
(en)
|
2000-09-26 |
2006-05-30 |
The Regents Of The University Of Michigan |
Methods for inhibition of HIV replication using a small molecule inhibitor
|
|
US20020111290A1
(en)
|
2000-12-01 |
2002-08-15 |
Bernhard Homey |
Uses of mammalian genes and related reagents
|
|
AU2002327164A1
(en)
|
2001-01-29 |
2002-12-09 |
Idec Pharmaceuticals Corporation |
Engineered tetravalent antibodies and methods of use
|
|
US6818406B2
(en)
|
2001-03-23 |
2004-11-16 |
Mayo Foundation For Medical Education And Research |
Rheumatoid arthritis markers
|
|
US7442512B2
(en)
|
2001-11-30 |
2008-10-28 |
Chemocentryx, Inc. |
Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
|
|
US7413866B2
(en)
|
2001-11-30 |
2008-08-19 |
Chemocentryx, Inc. |
Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
CA2487932A1
(en)
|
2002-05-30 |
2003-12-11 |
Macrogenics, Inc. |
Cd16a binding proteins and use for the treatment of immune disorders
|
|
AU2003298607B9
(en)
|
2002-10-29 |
2011-08-04 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
US7964194B2
(en)
|
2002-11-15 |
2011-06-21 |
Morehouse School Of Medicine |
Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation
|
|
US7919083B2
(en)
|
2002-11-15 |
2011-04-05 |
Morehouse School Of Medicine |
Anti-chemokine and associated receptors antibodies for inhibition of growth of neoplasms
|
|
EP1572116A4
(en)
|
2002-11-26 |
2007-12-12 |
Genentech Inc |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE DISEASES
|
|
CA2520853A1
(en)
|
2003-03-28 |
2005-03-31 |
Centocor, Inc. |
Anti-amyloid antibodies, compositions, methods and uses
|
|
WO2005110492A2
(en)
|
2004-04-12 |
2005-11-24 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Method of using adenoviral vectors to induce an immune response
|
|
CA2501422C
(en)
|
2004-04-29 |
2014-08-12 |
University Of Rochester |
Lymphoid chemokines in the diagnosis, monitoring and treatment of autoimmune disease
|
|
AU2005256113B2
(en)
|
2004-07-09 |
2011-02-10 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-glypican 3 antibody
|
|
BRPI0518994A2
(pt)
|
2004-12-31 |
2008-12-02 |
Biogen Idec Inc |
anticorpos ou polipeptÍdeos que se ligam a br3, seus usos e formulaÇÕes lÍquidas
|
|
JP5838021B2
(ja)
|
2005-04-15 |
2015-12-24 |
マクロジェニクス,インコーポレーテッド |
共有結合型ダイアボディとその使用
|
|
WO2006117910A1
(ja)
|
2005-04-28 |
2006-11-09 |
Mochida Pharmaceutical Co., Ltd. |
抗血小板膜糖蛋白質ⅵモノクローナル抗体
|
|
US20070136826A1
(en)
|
2005-12-02 |
2007-06-14 |
Biogen Idec Inc. |
Anti-mouse CD20 antibodies and uses thereof
|
|
GB0607774D0
(en)
*
|
2006-04-20 |
2006-05-31 |
Renovo Group Plc |
Medicaments
|
|
EP2021016B1
(en)
|
2006-04-21 |
2016-01-06 |
Janssen Biotech, Inc. |
Cxcl-13 antagonists and tnf-alpha antagonists for use in a combination therapy
|
|
US20080227704A1
(en)
|
2006-12-21 |
2008-09-18 |
Kamens Joanne S |
CXCL13 binding proteins
|
|
US20080199481A1
(en)
|
2007-02-21 |
2008-08-21 |
Astrazeneca Ab |
Compounds
|
|
AU2008232536A1
(en)
|
2007-03-30 |
2008-10-09 |
Centocor, Inc. |
CXCL13 antagonists and their use for the treatment of inflammatory diseases
|
|
US20110300167A1
(en)
*
|
2008-11-04 |
2011-12-08 |
Mcmurry Thomas J |
Cxcr5 receptor compounds
|
|
EP2611832B1
(en)
|
2010-09-02 |
2017-11-29 |
Vaccinex, Inc. |
Anti-cxcl13 antibodies and methods of using the same
|
|
WO2013102123A2
(en)
|
2011-12-28 |
2013-07-04 |
Novelmed Therapeutics, Inc. |
Aglycosylated human antibody and fusion protein and uses thereof
|
|
JP6363623B2
(ja)
|
2013-01-31 |
2018-07-25 |
ヴァクシネックス, インコーポレイテッド |
免疫グロブリンaのレベルを増大するための方法
|
|
CA2902442A1
(en)
|
2013-03-08 |
2014-09-12 |
Vaccinex, Inc. |
Anti-cxcl13 antibodies and associated epitope sequences
|