JP2015057052A5 - - Google Patents
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- JP2015057052A5 JP2015057052A5 JP2014184006A JP2014184006A JP2015057052A5 JP 2015057052 A5 JP2015057052 A5 JP 2015057052A5 JP 2014184006 A JP2014184006 A JP 2014184006A JP 2014184006 A JP2014184006 A JP 2014184006A JP 2015057052 A5 JP2015057052 A5 JP 2015057052A5
- Authority
- JP
- Japan
- Prior art keywords
- adenovirus
- protein
- recombinant adenovirus
- seq
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 241000701161 unidentified adenovirus Species 0.000 claims 55
- 239000012634 fragment Substances 0.000 claims 15
- 210000000234 capsid Anatomy 0.000 claims 13
- 101710094396 Hexon protein Proteins 0.000 claims 12
- 101710145505 Fiber protein Proteins 0.000 claims 10
- 101710173835 Penton protein Proteins 0.000 claims 9
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
- 108700019146 Transgenes Proteins 0.000 claims 5
- 125000000539 amino acid group Chemical group 0.000 claims 5
- 150000007523 nucleic acids Chemical group 0.000 claims 5
- 108090000565 Capsid Proteins Proteins 0.000 claims 4
- 241000282693 Cercopithecidae Species 0.000 claims 4
- 102100023321 Ceruloplasmin Human genes 0.000 claims 4
- 101000833492 Homo sapiens Jouberin Proteins 0.000 claims 4
- 101000651236 Homo sapiens NCK-interacting protein with SH3 domain Proteins 0.000 claims 4
- 102100024407 Jouberin Human genes 0.000 claims 4
- 101710087110 ORF6 protein Proteins 0.000 claims 4
- 101710159752 Poly(3-hydroxyalkanoate) polymerase subunit PhaE Proteins 0.000 claims 4
- 101710130262 Probable Vpr-like protein Proteins 0.000 claims 4
- 101710110895 Uncharacterized 7.3 kDa protein in cox-rep intergenic region Proteins 0.000 claims 4
- 101710095001 Uncharacterized protein in nifU 5'region Proteins 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 230000010076 replication Effects 0.000 claims 4
- 101000768957 Acholeplasma phage L2 Uncharacterized 37.2 kDa protein Proteins 0.000 claims 3
- 101000823746 Acidianus ambivalens Uncharacterized 17.7 kDa protein in bps2 3'region Proteins 0.000 claims 3
- 101000916369 Acidianus ambivalens Uncharacterized protein in sor 5'region Proteins 0.000 claims 3
- 101000769342 Acinetobacter guillouiae Uncharacterized protein in rpoN-murA intergenic region Proteins 0.000 claims 3
- 101000823696 Actinobacillus pleuropneumoniae Uncharacterized glycosyltransferase in aroQ 3'region Proteins 0.000 claims 3
- 101000786513 Agrobacterium tumefaciens (strain 15955) Uncharacterized protein outside the virF region Proteins 0.000 claims 3
- 101000618005 Alkalihalobacillus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4) Uncharacterized protein BpOF4_00885 Proteins 0.000 claims 3
- 102100020724 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 Human genes 0.000 claims 3
- 101000967489 Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571) Uncharacterized protein AZC_3924 Proteins 0.000 claims 3
- 101000823761 Bacillus licheniformis Uncharacterized 9.4 kDa protein in flaL 3'region Proteins 0.000 claims 3
- 101000819719 Bacillus methanolicus Uncharacterized N-acetyltransferase in lysA 3'region Proteins 0.000 claims 3
- 101000789586 Bacillus subtilis (strain 168) UPF0702 transmembrane protein YkjA Proteins 0.000 claims 3
- 101000792624 Bacillus subtilis (strain 168) Uncharacterized protein YbxH Proteins 0.000 claims 3
- 101000790792 Bacillus subtilis (strain 168) Uncharacterized protein YckC Proteins 0.000 claims 3
- 101000819705 Bacillus subtilis (strain 168) Uncharacterized protein YlxR Proteins 0.000 claims 3
- 101000948218 Bacillus subtilis (strain 168) Uncharacterized protein YtxJ Proteins 0.000 claims 3
- 101000718627 Bacillus thuringiensis subsp. kurstaki Putative RNA polymerase sigma-G factor Proteins 0.000 claims 3
- 101000641200 Bombyx mori densovirus Putative non-structural protein Proteins 0.000 claims 3
- 101000947633 Claviceps purpurea Uncharacterized 13.8 kDa protein Proteins 0.000 claims 3
- 101000948901 Enterobacteria phage T4 Uncharacterized 16.0 kDa protein in segB-ipI intergenic region Proteins 0.000 claims 3
- 101000805958 Equine herpesvirus 4 (strain 1942) Virion protein US10 homolog Proteins 0.000 claims 3
- 101000790442 Escherichia coli Insertion element IS2 uncharacterized 11.1 kDa protein Proteins 0.000 claims 3
- 101000788354 Escherichia phage P2 Uncharacterized 8.2 kDa protein in gpA 5'region Proteins 0.000 claims 3
- 101000770304 Frankia alni UPF0460 protein in nifX-nifW intergenic region Proteins 0.000 claims 3
- 101000797344 Geobacillus stearothermophilus Putative tRNA (cytidine(34)-2'-O)-methyltransferase Proteins 0.000 claims 3
- 101000748410 Geobacillus stearothermophilus Uncharacterized protein in fumA 3'region Proteins 0.000 claims 3
- 101000772675 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) UPF0438 protein HI_0847 Proteins 0.000 claims 3
- 101000631019 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) Uncharacterized protein HI_0350 Proteins 0.000 claims 3
- 101000768938 Haemophilus phage HP1 (strain HP1c1) Uncharacterized 8.9 kDa protein in int-C1 intergenic region Proteins 0.000 claims 3
- 101000785414 Homo sapiens Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 Proteins 0.000 claims 3
- 101000782488 Junonia coenia densovirus (isolate pBRJ/1990) Putative non-structural protein NS2 Proteins 0.000 claims 3
- 101000811523 Klebsiella pneumoniae Uncharacterized 55.8 kDa protein in cps region Proteins 0.000 claims 3
- 101000818409 Lactococcus lactis subsp. lactis Uncharacterized HTH-type transcriptional regulator in lacX 3'region Proteins 0.000 claims 3
- 101000878851 Leptolyngbya boryana Putative Fe(2+) transport protein A Proteins 0.000 claims 3
- 101000758828 Methanosarcina barkeri (strain Fusaro / DSM 804) Uncharacterized protein Mbar_A1602 Proteins 0.000 claims 3
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 claims 3
- 101001122401 Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) Non-structural protein ORF3 Proteins 0.000 claims 3
- 101001055788 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) Pentapeptide repeat protein MfpA Proteins 0.000 claims 3
- 101000740670 Orgyia pseudotsugata multicapsid polyhedrosis virus Protein C42 Proteins 0.000 claims 3
- 101000769182 Photorhabdus luminescens Uncharacterized protein in pnp 3'region Proteins 0.000 claims 3
- 101000961392 Pseudescherichia vulneris Uncharacterized 29.9 kDa protein in crtE 3'region Proteins 0.000 claims 3
- 101000731030 Pseudomonas oleovorans Poly(3-hydroxyalkanoate) polymerase 2 Proteins 0.000 claims 3
- 101001065485 Pseudomonas putida Probable fatty acid methyltransferase Proteins 0.000 claims 3
- 101000711023 Rhizobium leguminosarum bv. trifolii Uncharacterized protein in tfuA 3'region Proteins 0.000 claims 3
- 101000948156 Rhodococcus erythropolis Uncharacterized 47.3 kDa protein in thcA 5'region Proteins 0.000 claims 3
- 101000917565 Rhodococcus fascians Uncharacterized 33.6 kDa protein in fasciation locus Proteins 0.000 claims 3
- 101000790284 Saimiriine herpesvirus 2 (strain 488) Uncharacterized 9.5 kDa protein in DHFR 3'region Proteins 0.000 claims 3
- 101000936719 Streptococcus gordonii Accessory Sec system protein Asp3 Proteins 0.000 claims 3
- 101000788499 Streptomyces coelicolor Uncharacterized oxidoreductase in mprA 5'region Proteins 0.000 claims 3
- 101001102841 Streptomyces griseus Purine nucleoside phosphorylase ORF3 Proteins 0.000 claims 3
- 101000708557 Streptomyces lincolnensis Uncharacterized 17.2 kDa protein in melC2-rnhH intergenic region Proteins 0.000 claims 3
- 101000649826 Thermotoga neapolitana Putative anti-sigma factor antagonist TM1081 homolog Proteins 0.000 claims 3
- 101000827562 Vibrio alginolyticus Uncharacterized protein in proC 3'region Proteins 0.000 claims 3
- 101000778915 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) Uncharacterized membrane protein VP2115 Proteins 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 210000004899 c-terminal region Anatomy 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 3
- 239000012678 infectious agent Substances 0.000 claims 3
- 101000621943 Acholeplasma phage L2 Probable integrase/recombinase Proteins 0.000 claims 2
- 101000618348 Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) Uncharacterized protein Alvin_0065 Proteins 0.000 claims 2
- 101000781117 Autographa californica nuclear polyhedrosis virus Uncharacterized 12.4 kDa protein in CTL-LEF2 intergenic region Proteins 0.000 claims 2
- 101000708323 Azospirillum brasilense Uncharacterized 28.8 kDa protein in nifR3-like 5'region Proteins 0.000 claims 2
- 101000770311 Azotobacter chroococcum mcd 1 Uncharacterized 19.8 kDa protein in nifW 5'region Proteins 0.000 claims 2
- 101000748761 Bacillus subtilis (strain 168) Uncharacterized MFS-type transporter YcxA Proteins 0.000 claims 2
- 101000765620 Bacillus subtilis (strain 168) Uncharacterized protein YlxP Proteins 0.000 claims 2
- 101000916134 Bacillus subtilis (strain 168) Uncharacterized protein YqxJ Proteins 0.000 claims 2
- 101000754349 Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) UPF0065 protein BP0148 Proteins 0.000 claims 2
- 101000827633 Caldicellulosiruptor sp. (strain Rt8B.4) Uncharacterized 23.9 kDa protein in xynA 3'region Proteins 0.000 claims 2
- 101000947628 Claviceps purpurea Uncharacterized 11.8 kDa protein Proteins 0.000 claims 2
- 101000686796 Clostridium perfringens Replication protein Proteins 0.000 claims 2
- 102100031725 Cortactin-binding protein 2 Human genes 0.000 claims 2
- 101150029662 E1 gene Proteins 0.000 claims 2
- 101000788129 Escherichia coli Uncharacterized protein in sul1 3'region Proteins 0.000 claims 2
- 101000788370 Escherichia phage P2 Uncharacterized 12.9 kDa protein in GpA 3'region Proteins 0.000 claims 2
- 101000787096 Geobacillus stearothermophilus Uncharacterized protein in gldA 3'region Proteins 0.000 claims 2
- 101000976889 Haemophilus phage HP1 (strain HP1c1) Uncharacterized 19.2 kDa protein in cox-rep intergenic region Proteins 0.000 claims 2
- 241001135569 Human adenovirus 5 Species 0.000 claims 2
- 241000193096 Human adenovirus B3 Species 0.000 claims 2
- 101000908757 Human adenovirus C serotype 2 Early 4 ORF4 protein Proteins 0.000 claims 2
- 101000827627 Klebsiella pneumoniae Putative low molecular weight protein-tyrosine-phosphatase Proteins 0.000 claims 2
- 101001130841 Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) Non-structural protein ORF5 Proteins 0.000 claims 2
- 101710197985 Probable protein Rev Proteins 0.000 claims 2
- 102100040307 Protein FAM3B Human genes 0.000 claims 2
- 101000974028 Rhizobium leguminosarum bv. viciae (strain 3841) Putative cystathionine beta-lyase Proteins 0.000 claims 2
- 101000756519 Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) Uncharacterized protein RCAP_rcc00048 Proteins 0.000 claims 2
- 101000948219 Rhodococcus erythropolis Uncharacterized 11.5 kDa protein in thcD 3'region Proteins 0.000 claims 2
- 101000936711 Streptococcus gordonii Accessory secretory protein Asp4 Proteins 0.000 claims 2
- 101000929863 Streptomyces cinnamonensis Monensin polyketide synthase putative ketoacyl reductase Proteins 0.000 claims 2
- 101000788468 Streptomyces coelicolor Uncharacterized protein in mprR 3'region Proteins 0.000 claims 2
- 101000845085 Streptomyces violaceoruber Granaticin polyketide synthase putative ketoacyl reductase 1 Proteins 0.000 claims 2
- 101000711771 Thiocystis violacea Uncharacterized 76.5 kDa protein in phbC 3'region Proteins 0.000 claims 2
- 101710198378 Uncharacterized 10.8 kDa protein in cox-rep intergenic region Proteins 0.000 claims 2
- 101710134973 Uncharacterized 9.7 kDa protein in cox-rep intergenic region Proteins 0.000 claims 2
- 101000711318 Vibrio alginolyticus Uncharacterized 11.6 kDa protein in scrR 3'region Proteins 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000000835 fiber Substances 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33195101P | 2001-11-21 | 2001-11-21 | |
| US60/331,951 | 2001-11-21 | ||
| US36679802P | 2002-03-22 | 2002-03-22 | |
| US60/366,798 | 2002-03-22 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013167091A Division JP2013252144A (ja) | 2001-11-21 | 2013-08-09 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016220443A Division JP2017070292A (ja) | 2001-11-21 | 2016-11-11 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2016220444A Division JP2017035111A (ja) | 2001-11-21 | 2016-11-11 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015057052A JP2015057052A (ja) | 2015-03-26 |
| JP2015057052A5 true JP2015057052A5 (enExample) | 2015-05-07 |
Family
ID=26987985
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003547559A Withdrawn JP2005511035A (ja) | 2001-11-21 | 2002-11-20 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2009018231A Expired - Fee Related JP5715749B2 (ja) | 2001-11-21 | 2009-01-29 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2010225018A Pending JP2011055835A (ja) | 2001-11-21 | 2010-10-04 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2013167091A Pending JP2013252144A (ja) | 2001-11-21 | 2013-08-09 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2014184003A Withdrawn JP2015057051A (ja) | 2001-11-21 | 2014-09-10 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2014184006A Ceased JP2015057052A (ja) | 2001-11-21 | 2014-09-10 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2016220440A Pending JP2017035110A (ja) | 2001-11-21 | 2016-11-11 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2016220444A Pending JP2017035111A (ja) | 2001-11-21 | 2016-11-11 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2016220443A Pending JP2017070292A (ja) | 2001-11-21 | 2016-11-11 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003547559A Withdrawn JP2005511035A (ja) | 2001-11-21 | 2002-11-20 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2009018231A Expired - Fee Related JP5715749B2 (ja) | 2001-11-21 | 2009-01-29 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2010225018A Pending JP2011055835A (ja) | 2001-11-21 | 2010-10-04 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2013167091A Pending JP2013252144A (ja) | 2001-11-21 | 2013-08-09 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2014184003A Withdrawn JP2015057051A (ja) | 2001-11-21 | 2014-09-10 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016220440A Pending JP2017035110A (ja) | 2001-11-21 | 2016-11-11 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2016220444A Pending JP2017035111A (ja) | 2001-11-21 | 2016-11-11 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
| JP2016220443A Pending JP2017070292A (ja) | 2001-11-21 | 2016-11-11 | サルアデノウイルス核酸およびアミノ酸配列、それを含むベクターおよび使用方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (5) | US7247472B2 (enExample) |
| EP (4) | EP2301582B1 (enExample) |
| JP (9) | JP2005511035A (enExample) |
| KR (1) | KR100987360B1 (enExample) |
| CN (1) | CN1578678B (enExample) |
| AU (1) | AU2002365366B2 (enExample) |
| BR (1) | BR0214350A (enExample) |
| CA (3) | CA2852277C (enExample) |
| CO (1) | CO5590973A2 (enExample) |
| HU (3) | HU230488B1 (enExample) |
| IL (5) | IL161584A0 (enExample) |
| MX (2) | MXPA04004876A (enExample) |
| NO (3) | NO332692B1 (enExample) |
| NZ (3) | NZ550416A (enExample) |
| PH (1) | PH12016500338A1 (enExample) |
| PL (1) | PL209133B1 (enExample) |
| SG (2) | SG2013034475A (enExample) |
| WO (1) | WO2003046124A2 (enExample) |
| ZA (1) | ZA200403117B (enExample) |
Families Citing this family (120)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7344872B2 (en) | 2001-06-22 | 2008-03-18 | The Trustees Of The University Of Pennsylvania | Method for rapid screening of bacterial transformants and novel simian adenovirus proteins |
| US20040136963A1 (en) * | 2001-06-22 | 2004-07-15 | The Trustees Of The University Of Pennsylvania | Simian adenovirus vectors and methods of use |
| MXPA04004876A (es) * | 2001-11-21 | 2004-07-30 | Univ Pennsylvania | Secuencias de acido nucleico y de aminoacido de adenovirus de simio, vectores que contienen los mismos y metodos de uso. |
| US8232255B2 (en) | 2002-10-23 | 2012-07-31 | Glaxosmithkline Biologicals S.A. | Methods for vaccinating against malaria |
| WO2005001103A2 (en) * | 2003-06-20 | 2005-01-06 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| US7291498B2 (en) | 2003-06-20 | 2007-11-06 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| JP4814800B2 (ja) * | 2004-01-23 | 2011-11-16 | イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー | チンパンジーアデノウイルスワクチン担体 |
| WO2006078279A2 (en) * | 2004-04-28 | 2006-07-27 | The Trustees Of The University Of Pennsylvania | Sequential delivery of immunogenic molecules via adenovirus and adeno-associated virus-mediated administrations |
| US9592284B2 (en) * | 2004-04-28 | 2017-03-14 | The Trustees Of The University Of Pennsylvania | Immunization regimen with E4-deleted adenovirus prime and E1-deleted adenovirus boost |
| US7964196B2 (en) * | 2004-05-25 | 2011-06-21 | Chimeros, Inc. | Self-assembling nanoparticle drug delivery system |
| GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
| BRPI0518933A2 (pt) | 2004-11-16 | 2008-12-16 | Crucell Holland B V E Aeras Gl | adenovÍrus recombinante defeituoso de replicaÇço, vetor de polinucleotÍdeo recombinante, vacina multivalente da tuberculose, e, uso do antÍgeno tb10.4 de mycobacterium |
| EP1863520B1 (en) * | 2005-03-08 | 2014-12-31 | Aptose Biosciences Inc. | Use of interleukin 17e for the treatment of cancer |
| GB0513421D0 (en) | 2005-06-30 | 2005-08-03 | Glaxosmithkline Biolog Sa | Vaccines |
| JP2009533350A (ja) * | 2006-04-07 | 2009-09-17 | キメロス， インコーポレイテッド | Ｂ細胞悪性疾患を処置するための組成物および方法 |
| CN101437538A (zh) * | 2006-04-28 | 2009-05-20 | 宾夕法尼亚州立大学托管会 | 修饰的腺病毒六邻体蛋白和其应用 |
| US20090246220A1 (en) | 2006-08-28 | 2009-10-01 | Ertl Hildegund C J | Constructs for enhancing immune responses |
| CN103550764A (zh) | 2007-03-02 | 2014-02-05 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗组合物及其在刺激免疫反应中的用途 |
| US20090226525A1 (en) * | 2007-04-09 | 2009-09-10 | Chimeros Inc. | Self-assembling nanoparticle drug delivery system |
| WO2009073103A2 (en) * | 2007-11-28 | 2009-06-11 | The Trustees Of The University Of Pennsylvania | Simian subfamily b adenoviruses sadv-28,27,-29,-32,-33, and -35 and uses thereof |
| AU2014203073B2 (en) * | 2007-11-28 | 2016-07-07 | The Trustees Of The University Of Pennsylvania | Simian E adenovirus SAdV-30 |
| CN102131920B (zh) * | 2007-11-28 | 2013-11-06 | 宾夕法尼亚大学托管会 | 猿猴亚家族C腺病毒SAdV-40、-31和-34及其应用 |
| KR101662574B1 (ko) * | 2007-11-28 | 2016-10-05 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 유인원 ｅ 아데노바이러스 ｓａｄｖ-39, -25.2, -26, -30, -37, 및 -38 |
| EP2325298B1 (en) | 2008-03-04 | 2016-10-05 | The Trustees Of The University Of Pennsylvania | SIMIAN ADENOVIRUSES SAdV-36, -42.1, -42.2, AND -44 AND USES THEREOF |
| US9217155B2 (en) * | 2008-05-28 | 2015-12-22 | University Of Massachusetts | Isolation of novel AAV'S and uses thereof |
| EP2774985B1 (en) * | 2008-10-31 | 2016-12-14 | The Trustees Of The University Of Pennsylvania | Simian adenovirus SAdV-43 and uses thereof |
| WO2010085984A1 (en) * | 2009-02-02 | 2010-08-05 | Okairos Ag | Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof |
| HUE039908T2 (hu) | 2009-02-02 | 2019-02-28 | Glaxosmithkline Biologicals Sa | Majom adenovírusból származó nukleinsav- és aminosav-szekvenciák, azt tartalmazó vektorok és alkalmazásuk |
| BRPI1009873A2 (pt) | 2009-03-17 | 2016-03-08 | Glaxosmithkline Biolog Sa | detecção aperfeiçoada de expressão gênica |
| WO2010120874A2 (en) | 2009-04-14 | 2010-10-21 | Chimeros, Inc. | Chimeric therapeutics, compositions, and methods for using same |
| US8734809B2 (en) | 2009-05-28 | 2014-05-27 | University Of Massachusetts | AAV's and uses thereof |
| US8846031B2 (en) | 2009-05-29 | 2014-09-30 | The Trustees Of The University Of Pennsylvania | Simian adenovirus 41 and uses thereof |
| WO2011057254A2 (en) * | 2009-11-09 | 2011-05-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Simian adenoviral vector-based vaccines |
| WO2011057248A2 (en) | 2009-11-09 | 2011-05-12 | Genvec, Inc. | Simian adenovirus and methods of use |
| EP2558481B1 (en) * | 2010-04-14 | 2017-12-20 | Mogam Biotechnology Research Institute | Hexon isolated from simian adenovirus serotype 19, hypervariable region thereof and chimeric adenovirus using the same |
| DK2561073T3 (en) | 2010-04-23 | 2016-12-12 | Univ Massachusetts | Aav vectors targeted to central nervous system and methods of use thereof |
| CA3050894C (en) | 2010-04-23 | 2022-10-18 | University Of Massachusetts | Multicistronic expression constructs |
| CA2833912C (en) | 2010-04-23 | 2021-09-21 | University Of Massachusetts | Aav-based treatment of cholesterol-related disorders |
| PT3351636T (pt) * | 2010-05-14 | 2020-09-24 | Univ Oregon Health & Science | Vectores de hcmv e rhcmv recombinantes codificadores de um antigénio heterólogo isolado a partir de um vírus paramyxoviridae e seus usos |
| WO2012021730A2 (en) | 2010-08-11 | 2012-02-16 | Genvec, Inc. | Respiratory syncytial virus (rsv) vaccine |
| CA2808556A1 (en) | 2010-09-20 | 2012-03-29 | Crucell Holland B.V. | Therapeutic vaccination against active tuberculosis |
| EP2643465B1 (en) | 2010-11-23 | 2016-05-11 | The Trustees Of The University Of Pennsylvania | Subfamily e simian adenovirus a1321 and uses thereof |
| JP6055779B2 (ja) | 2010-12-27 | 2016-12-27 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | ナトリウム利尿ペプチドを含む組成物およびその使用方法 |
| WO2012089231A1 (en) * | 2010-12-30 | 2012-07-05 | Okairòs Ag | Paramyxovirus vaccines |
| US9267112B2 (en) | 2011-05-10 | 2016-02-23 | The Regents Of The University Of California | Adenovirus isolated from Titi Monkeys |
| US10221218B2 (en) | 2011-05-10 | 2019-03-05 | The Regents Of The University Of California | Adenovirus isolated from titi monkeys |
| GB201108879D0 (en) * | 2011-05-25 | 2011-07-06 | Isis Innovation | Vector |
| TWI575070B (zh) | 2011-07-12 | 2017-03-21 | 傳斯堅公司 | Ｈｂｖ聚合酶突變體 |
| CA2847888A1 (en) | 2011-09-09 | 2013-03-14 | Biomed Realty, L.P. | Methods and compositions for controlling assembly of viral proteins |
| US20140348791A1 (en) * | 2011-09-09 | 2014-11-27 | Beth Israel Deaconess Medical Center, Inc. | Modified adenoviral vectors and methods of treatment using same |
| TW201318637A (zh) | 2011-09-29 | 2013-05-16 | Transgene Sa | 免疫療法組成物及用於治療ｃ型肝炎病毒感染之療程（一） |
| WO2013045668A2 (en) | 2011-09-29 | 2013-04-04 | Transgene Sa | Immunotherapy composition and regimen for treating hepatitis c virus infection |
| CA2850627C (en) * | 2011-10-05 | 2024-05-21 | Genvec, Inc. | Affenadenovirus (gorilla) or adenoviral vectors and methods of use |
| KR20140084201A (ko) | 2011-10-19 | 2014-07-04 | 알렉시온 파마 홀딩 | 알칼리성 포스파타제 및/또는 나트륨이뇨 펩티드를 포함하는 조성물 및 그의 사용 방법 |
| WO2013063019A1 (en) | 2011-10-28 | 2013-05-02 | The Wistar Institute Of Anatomy And Biology | Methods and compositions for enhancing the therapeutic effect of anti-tumor t cells |
| US10238755B2 (en) | 2011-11-30 | 2019-03-26 | The Wistar Institute Of Anatomy And Biology | Methods and compositions for regulation of cell aging, carcinogenesis and reprogramming |
| AU2013262626B2 (en) | 2012-05-18 | 2018-11-29 | The Trustees Of The University Of Pennsylvania | Subfamily E simian adenoviruses A1302, A1320, A1331 and A1337 and uses thereof |
| EP2892554B1 (en) | 2012-09-07 | 2020-08-26 | Emory University | Hiv immune stimulating compositions comprising recombinantly expressed pili on bacteria and methods related thereto |
| US9683268B2 (en) * | 2012-09-19 | 2017-06-20 | Beth Israel Deaconess | Viruses associated with immunodeficiency and enteropathy and methods using same |
| CA2891349C (en) * | 2012-11-16 | 2023-07-18 | Beth Israel Deaconess Medical Center, Inc. | Recombinant adenoviruses and use thereof |
| CN105189755A (zh) * | 2013-01-15 | 2015-12-23 | 加利福尼亚大学董事会 | 腺病毒及其用途 |
| US9624510B2 (en) | 2013-03-01 | 2017-04-18 | The Wistar Institute | Adenoviral vectors comprising partial deletions of E3 |
| SG11201507393TA (en) | 2013-03-14 | 2015-10-29 | Salk Inst For Biological Studi | Oncolytic adenovirus compositions |
| US9402888B2 (en) | 2013-03-14 | 2016-08-02 | The Wistar Institute Of Anatomy And Biology | Methods and compositions for treating cancer |
| EP3524262A1 (en) * | 2013-11-01 | 2019-08-14 | Pfizer Inc | Vectors for expression of prostate-associated antigens |
| US10577627B2 (en) | 2014-06-09 | 2020-03-03 | Voyager Therapeutics, Inc. | Chimeric capsids |
| ES2899913T3 (es) | 2014-09-24 | 2022-03-15 | Salk Inst For Biological Studi | Virus tumorales oncolíticos y métodos de uso |
| CN114150018A (zh) | 2014-10-02 | 2022-03-08 | 威斯塔解剖学和生物学研究所 | 治疗癌症的方法和组合物 |
| WO2016057387A1 (en) | 2014-10-06 | 2016-04-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for isolation of circulating tumor cells (ctc) |
| WO2016065001A1 (en) | 2014-10-21 | 2016-04-28 | University Of Massachusetts | Recombinant aav variants and uses thereof |
| EP3215191B1 (en) | 2014-11-05 | 2024-08-14 | Voyager Therapeutics, Inc. | Aadc polynucleotides for the treatment of parkinson's disease |
| KR20230145206A (ko) | 2014-11-14 | 2023-10-17 | 보이저 테라퓨틱스, 인크. | 조절성 폴리뉴클레오티드 |
| CN114717264A (zh) | 2014-11-14 | 2022-07-08 | 沃雅戈治疗公司 | 治疗肌萎缩性侧索硬化(als)的组合物和方法 |
| US11697825B2 (en) | 2014-12-12 | 2023-07-11 | Voyager Therapeutics, Inc. | Compositions and methods for the production of scAAV |
| CA2975432A1 (en) | 2015-02-13 | 2016-08-18 | Transgene Sa | Immunotherapeutic vaccine and antibody combination therapy |
| WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
| WO2016198621A1 (en) * | 2015-06-12 | 2016-12-15 | Glaxosmithkline Biologicals Sa | Adenovirus polynucleotides and polypeptides |
| AU2016362477A1 (en) | 2015-12-02 | 2018-06-14 | Voyager Therapeutics, Inc. | Assays for the detection of AAV neutralizing antibodies |
| EP3416668A4 (en) | 2016-02-18 | 2020-02-19 | The Wistar Institute Of Anatomy And Biology | METHOD AND COMPOSITIONS FOR TREATING MELANOMA |
| EP3390645B1 (en) | 2016-02-23 | 2022-09-14 | Salk Institute for Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| EP3448987A4 (en) | 2016-04-29 | 2020-05-27 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| CA3023022A1 (en) | 2016-05-04 | 2017-11-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
| IL297576B2 (en) | 2016-05-18 | 2024-02-01 | Voyager Therapeutics Inc | Compositions and methods of treating huntington's disease |
| US10584337B2 (en) | 2016-05-18 | 2020-03-10 | Voyager Therapeutics, Inc. | Modulatory polynucleotides |
| EP3490610A4 (en) * | 2016-08-01 | 2020-05-20 | The Wistar Institute Of Anatomy And Biology | COMPOSITIONS AND METHODS FOR REPLICATION-DEFICIENT ADENOVIRAL VECTORS FOR VACCINE APPLICATIONS |
| CA3034089A1 (en) | 2016-08-18 | 2018-02-22 | The Regents Of The University Of California | Crispr-cas genome engineering via a modular aav delivery system |
| EP3831281B1 (en) | 2016-08-30 | 2026-02-25 | The Regents of The University of California | Devices and systems for biomedical targeting and delivery |
| WO2018069316A2 (en) | 2016-10-10 | 2018-04-19 | Transgene Sa | Immunotherapeutic product and mdsc modulator combination therapy |
| KR20190075964A (ko) | 2016-10-13 | 2019-07-01 | 유니버시티 오브 매사추세츠 | Aav 캡시드 설계 |
| AU2017375633C1 (en) | 2016-12-12 | 2023-04-27 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| MX2019013172A (es) | 2017-05-05 | 2020-09-07 | Voyager Therapeutics Inc | Composiciones y metodos para tratar la enfermedad de huntington. |
| EP3618839A4 (en) | 2017-05-05 | 2021-06-09 | Voyager Therapeutics, Inc. | COMPOSITIONS AND METHODS OF TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| CA3070087A1 (en) | 2017-07-17 | 2019-01-24 | Voyager Therapeutics, Inc. | Trajectory array guide system |
| US11512327B2 (en) | 2017-08-03 | 2022-11-29 | Voyager Therapeutics, Inc. | Compositions and methods for delivery of AAV |
| MX2020003042A (es) | 2017-09-29 | 2020-11-18 | Voyager Therapeutics Inc | Rescate del fenotipo neurológico central y periférico de la ataxia de friedreich mediante administración intravenosa. |
| WO2019079242A1 (en) | 2017-10-16 | 2019-04-25 | Voyager Therapeutics, Inc. | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| TW202413649A (zh) | 2017-10-16 | 2024-04-01 | 美商航海家醫療公司 | 肌萎縮性脊髓側索硬化症(als)之治療 |
| WO2019118480A1 (en) | 2017-12-11 | 2019-06-20 | Beth Israel Deaconess Medical Center, Inc. | Recombinant adenoviruses and uses thereof |
| BR112020019942A2 (pt) | 2018-04-09 | 2021-01-26 | Salk Institute For Biological Studies | composições de adenovírus oncolítico com propriedades de replicação aprimoradas |
| CN112424359A (zh) | 2018-05-15 | 2021-02-26 | 沃雅戈治疗公司 | 用于治疗帕金森氏病的组合物和方法 |
| WO2019241486A1 (en) | 2018-06-13 | 2019-12-19 | Voyager Therapeutics, Inc. | Engineered 5' untranslated regions (5' utr) for aav production |
| CA3106078A1 (en) | 2018-07-17 | 2020-01-23 | Junghun Lee | Treatment of neuropathy with dna constructs expressing igf-1 isoforms |
| WO2020023612A1 (en) | 2018-07-24 | 2020-01-30 | Voyager Therapeutics, Inc. | Systems and methods for producing gene therapy formulations |
| US12281321B2 (en) | 2018-09-28 | 2025-04-22 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
| WO2020072849A1 (en) | 2018-10-04 | 2020-04-09 | Voyager Therapeutics, Inc. | Methods for measuring the titer and potency of viral vector particles |
| AU2019354793A1 (en) | 2018-10-05 | 2021-05-13 | Voyager Therapeutics, Inc. | Engineered nucleic acid constructs encoding AAV production proteins |
| WO2020081490A1 (en) | 2018-10-15 | 2020-04-23 | Voyager Therapeutics, Inc. | EXPRESSION VECTORS FOR LARGE-SCALE PRODUCTION OF rAAV IN THE BACULOVIRUS/Sf9 SYSTEM |
| CN119390787A (zh) | 2019-01-31 | 2025-02-07 | 俄勒冈健康与科学大学 | 用于aav衣壳的使用转录依赖性定向进化的方法 |
| CN114269363A (zh) * | 2019-04-17 | 2022-04-01 | 威斯达研究所 | 用于hiv疫苗应用的复制缺陷型腺病毒载体 |
| NL2023464B1 (en) | 2019-07-09 | 2021-02-02 | Academisch Ziekenhuis Leiden | Oncolytic Non-human adenoviruses and uses thereof |
| KR20230038496A (ko) | 2020-07-13 | 2023-03-20 | 트랜스진 | 면역 억제의 치료 |
| MX2023008826A (es) | 2021-02-01 | 2023-09-15 | Regenxbio Inc | Terapia génica para lipofuscinosis neuronal ceroidea. |
| CN112831524B (zh) * | 2021-02-20 | 2023-06-13 | 苏州相奕生物技术有限公司 | 人工改造的重组腺病毒载体、由其包装的病毒及其应用 |
| US20250277234A1 (en) * | 2021-03-29 | 2025-09-04 | Genematrix, Inc. | Recombinant chimeric adenoviral vector substituted by knob gene of chimpanzee adenovirus serotype 6, and application thereof |
| WO2022218997A1 (en) | 2021-04-12 | 2022-10-20 | Centre National De La Recherche Scientifique (Cnrs) | Novel universal vaccine presenting system |
| KR102874372B1 (ko) * | 2022-03-03 | 2025-10-23 | (주)진매트릭스 | 사스-코로나바이러스-2 감염증 예방용 재조합 발현 벡터 및 그 응용 |
| WO2023213764A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5240846A (en) | 1989-08-22 | 1993-08-31 | The Regents Of The University Of Michigan | Gene therapy vector for cystic fibrosis |
| US6174666B1 (en) | 1992-03-27 | 2001-01-16 | The United States Of America As Represented By The Department Of Health And Human Services | Method of eliminating inhibitory/instability regions from mRNA |
| JPH10507758A (ja) | 1994-10-19 | 1998-07-28 | ジェネティック セラピー，インコーポレイテッド | アデノウイルスおよび免疫抑制剤同時反復投与を伴う遺伝子治療 |
| CA2203809C (en) | 1994-10-28 | 2008-06-03 | James M. Wilson | Recombinant adenovirus and methods of use thereof |
| US5856152A (en) | 1994-10-28 | 1999-01-05 | The Trustees Of The University Of Pennsylvania | Hybrid adenovirus-AAV vector and methods of use therefor |
| US5770442A (en) * | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
| US6127525A (en) | 1995-02-21 | 2000-10-03 | Cornell Research Foundation, Inc. | Chimeric adenoviral coat protein and methods of using same |
| US5698202A (en) | 1995-06-05 | 1997-12-16 | The Wistar Institute Of Anatomy & Biology | Replication-defective adenovirus human type 5 recombinant as a rabies vaccine carrier |
| US6019978A (en) | 1995-06-05 | 2000-02-01 | The Wistar Institute Of Anatomy And Biology | Replication-defective adenovirus human type 5 recombinant as a vaccine carrier |
| US6083716A (en) | 1996-09-06 | 2000-07-04 | The Trustees Of The University Of Pennsylvania | Chimpanzee adenovirus vectors |
| CA2264482A1 (en) | 1996-09-06 | 1998-03-12 | The Trustees Of The University Of Pennsylvania | An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase |
| US5922315A (en) | 1997-01-24 | 1999-07-13 | Genetic Therapy, Inc. | Adenoviruses having altered hexon proteins |
| US5891994A (en) | 1997-07-11 | 1999-04-06 | Thymon L.L.C. | Methods and compositions for impairing multiplication of HIV-1 |
| JP2001517454A (ja) | 1997-09-19 | 2001-10-09 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 組換えアデノ随伴ウイルスの産生に有用な方法および細胞株 |
| WO1999014354A1 (en) | 1997-09-19 | 1999-03-25 | The Trustees Of The University Of The Pennsylvania | Methods and vector constructs useful for production of recombinant aav |
| GB9720585D0 (en) | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
| ATE286138T1 (de) | 1998-03-20 | 2005-01-15 | Univ Pennsylvania | Zusammensetzungen und verfahren zur helfer-freien herstellung von rekombinante adeno-assoziierten viren |
| US20030017138A1 (en) * | 1998-07-08 | 2003-01-23 | Menzo Havenga | Chimeric adenoviruses |
| WO2000011140A1 (en) | 1998-08-20 | 2000-03-02 | The Wistar Institute Of Anatomy And Biology | Methods of augmenting mucosal immunity through systemic priming and mucosal boosting |
| US6258595B1 (en) | 1999-03-18 | 2001-07-10 | The Trustees Of The University Of Pennsylvania | Compositions and methods for helper-free production of recombinant adeno-associated viruses |
| JP2003530307A (ja) | 1999-07-06 | 2003-10-14 | メルク・アンド・カンパニー・インコーポレーテッド | ｇａｇ遺伝子保有アデノウイルスＨＩＶワクチン |
| JP2003529559A (ja) | 2000-01-31 | 2003-10-07 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規用途 |
| AU2001234981A1 (en) | 2000-02-09 | 2001-08-20 | Genvec, Inc. | Adenoviral capsid containing chimeric protein ix |
| US7344872B2 (en) * | 2001-06-22 | 2008-03-18 | The Trustees Of The University Of Pennsylvania | Method for rapid screening of bacterial transformants and novel simian adenovirus proteins |
| US20040136963A1 (en) | 2001-06-22 | 2004-07-15 | The Trustees Of The University Of Pennsylvania | Simian adenovirus vectors and methods of use |
| AU2002308713B2 (en) | 2001-06-22 | 2008-05-15 | The Trustees Of The University Of Pennsylvania | Methods of inducing a cytotoxic immune response and recombinant simian adenovirus compositions useful therein |
| MXPA04004876A (es) * | 2001-11-21 | 2004-07-30 | Univ Pennsylvania | Secuencias de acido nucleico y de aminoacido de adenovirus de simio, vectores que contienen los mismos y metodos de uso. |
| US8232255B2 (en) | 2002-10-23 | 2012-07-31 | Glaxosmithkline Biologicals S.A. | Methods for vaccinating against malaria |
| WO2005001103A2 (en) | 2003-06-20 | 2005-01-06 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| US7291498B2 (en) | 2003-06-20 | 2007-11-06 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| CN1965086B (zh) | 2004-04-28 | 2012-12-26 | 宾夕法尼亚大学托管会 | 多价病毒载体和产生它的系统 |
| WO2006078279A2 (en) | 2004-04-28 | 2006-07-27 | The Trustees Of The University Of Pennsylvania | Sequential delivery of immunogenic molecules via adenovirus and adeno-associated virus-mediated administrations |
| US9592284B2 (en) | 2004-04-28 | 2017-03-14 | The Trustees Of The University Of Pennsylvania | Immunization regimen with E4-deleted adenovirus prime and E1-deleted adenovirus boost |
| BRPI0608798A2 (pt) | 2005-05-12 | 2011-03-15 | Glaxo Group Ltd | vetor de adenovìrus, composição imunogênica, uso de um vetor de adenovìrus, método para preparar um vetor, uso de um vetor de vìrus e um carreador ou adjuvante farmaceuticamente aceitável, e, proteìna de fusão |
| CN101437538A (zh) * | 2006-04-28 | 2009-05-20 | 宾夕法尼亚州立大学托管会 | 修饰的腺病毒六邻体蛋白和其应用 |
| JP5222289B2 (ja) | 2006-07-18 | 2013-06-26 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | マラリア用ワクチン |
| CN103550764A (zh) | 2007-03-02 | 2014-02-05 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗组合物及其在刺激免疫反应中的用途 |
| EP2777185B1 (en) | 2011-10-13 | 2016-08-24 | Telefonaktiebolaget LM Ericsson (publ) | Method and node related to channel estimation |
-
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- 2013-11-07 US US14/073,979 patent/US9133483B2/en not_active Expired - Fee Related
-
2014
- 2014-01-02 IL IL230292A patent/IL230292A/en active IP Right Grant
- 2014-03-13 IL IL231502A patent/IL231502A/en not_active IP Right Cessation
- 2014-09-10 JP JP2014184003A patent/JP2015057051A/ja not_active Withdrawn
- 2014-09-10 JP JP2014184006A patent/JP2015057052A/ja not_active Ceased
-
2015
- 2015-08-12 US US14/824,336 patent/US20170119873A9/en not_active Abandoned
-
2016
- 2016-02-19 PH PH12016500338A patent/PH12016500338A1/en unknown
- 2016-11-11 JP JP2016220440A patent/JP2017035110A/ja active Pending
- 2016-11-11 JP JP2016220444A patent/JP2017035111A/ja active Pending
- 2016-11-11 JP JP2016220443A patent/JP2017070292A/ja active Pending
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