JP2009544303A5 - - Google Patents
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- Publication number
- JP2009544303A5 JP2009544303A5 JP2009521375A JP2009521375A JP2009544303A5 JP 2009544303 A5 JP2009544303 A5 JP 2009544303A5 JP 2009521375 A JP2009521375 A JP 2009521375A JP 2009521375 A JP2009521375 A JP 2009521375A JP 2009544303 A5 JP2009544303 A5 JP 2009544303A5
- Authority
- JP
- Japan
- Prior art keywords
- recombinant
- padv
- adenovirus
- adenoviral vector
- fiber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000013598 vector Substances 0.000 claims description 64
- 241000701161 unidentified adenovirus Species 0.000 claims description 55
- 210000004027 cell Anatomy 0.000 claims description 52
- 108090000623 proteins and genes Proteins 0.000 claims description 43
- 238000000034 method Methods 0.000 claims description 39
- 101710145505 Fiber protein Proteins 0.000 claims description 27
- 239000000835 fiber Substances 0.000 claims description 21
- 239000000203 mixture Substances 0.000 claims description 20
- 241000188845 Porcine adenovirus Species 0.000 claims description 16
- 102000004169 proteins and genes Human genes 0.000 claims description 15
- 239000002773 nucleotide Substances 0.000 claims description 12
- 125000003729 nucleotide group Chemical group 0.000 claims description 12
- 229920001184 polypeptide Polymers 0.000 claims description 12
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 12
- 241000283690 Bos taurus Species 0.000 claims description 6
- 102000004127 Cytokines Human genes 0.000 claims description 6
- 108090000695 Cytokines Proteins 0.000 claims description 6
- 241001494479 Pecora Species 0.000 claims description 6
- 241001492389 Porcine adenovirus 3 Species 0.000 claims description 6
- 239000000427 antigen Substances 0.000 claims description 6
- 102000036639 antigens Human genes 0.000 claims description 6
- 108091007433 antigens Proteins 0.000 claims description 6
- 239000000122 growth hormone Substances 0.000 claims description 6
- 230000002163 immunogen Effects 0.000 claims description 6
- 239000002955 immunomodulating agent Substances 0.000 claims description 6
- 229940121354 immunomodulator Drugs 0.000 claims description 6
- 244000052769 pathogen Species 0.000 claims description 6
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 6
- 230000010076 replication Effects 0.000 claims description 6
- 230000001225 therapeutic effect Effects 0.000 claims description 6
- 108700026758 Adenovirus hexon capsid Proteins 0.000 claims description 4
- 241000271566 Aves Species 0.000 claims description 4
- 241000701157 Canine mastadenovirus A Species 0.000 claims description 4
- 241000598171 Human adenovirus sp. Species 0.000 claims description 4
- 241000701168 Murine adenovirus 1 Species 0.000 claims description 4
- 230000002950 deficient Effects 0.000 claims description 4
- 230000028993 immune response Effects 0.000 claims description 4
- 210000004962 mammalian cell Anatomy 0.000 claims description 4
- 229960005486 vaccine Drugs 0.000 claims description 4
- 108010051696 Growth Hormone Proteins 0.000 claims description 3
- 102000018997 Growth Hormone Human genes 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 claims description 3
- 230000002584 immunomodulator Effects 0.000 claims description 3
- 230000001939 inductive effect Effects 0.000 claims description 3
- 230000001717 pathogenic effect Effects 0.000 claims description 3
- 241000283073 Equus caballus Species 0.000 claims description 2
- 241000282414 Homo sapiens Species 0.000 claims description 2
- 241000700605 Viruses Species 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 210000000234 capsid Anatomy 0.000 claims description 2
- 238000012258 culturing Methods 0.000 claims description 2
- 210000005260 human cell Anatomy 0.000 claims description 2
- 102000039446 nucleic acids Human genes 0.000 claims description 2
- 108020004707 nucleic acids Proteins 0.000 claims description 2
- 150000007523 nucleic acids Chemical class 0.000 claims description 2
- 230000000644 propagated effect Effects 0.000 claims description 2
- 241000990167 unclassified Simian adenoviruses Species 0.000 claims description 2
- 208000015181 infectious disease Diseases 0.000 claims 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83398506P | 2006-07-28 | 2006-07-28 | |
| PCT/IB2007/002710 WO2008012682A2 (en) | 2006-07-28 | 2007-07-27 | Methods and compositions for increasing tissue tropism of recombinant adenoviral vectors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009544303A JP2009544303A (ja) | 2009-12-17 |
| JP2009544303A5 true JP2009544303A5 (enExample) | 2010-08-26 |
Family
ID=38981845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009521375A Pending JP2009544303A (ja) | 2006-07-28 | 2007-07-27 | 組換え型アデノウイルスベクターの組織親和性を増大させるための方法および組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8163544B2 (enExample) |
| EP (1) | EP2059602A4 (enExample) |
| JP (1) | JP2009544303A (enExample) |
| KR (1) | KR20090038910A (enExample) |
| CN (1) | CN101849012A (enExample) |
| AR (1) | AR062145A1 (enExample) |
| AU (1) | AU2007278887A1 (enExample) |
| BR (1) | BRPI0714932A2 (enExample) |
| CA (1) | CA2658805A1 (enExample) |
| MX (1) | MX2009000898A (enExample) |
| TW (1) | TW200829273A (enExample) |
| WO (1) | WO2008012682A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2658805A1 (en) * | 2006-07-28 | 2008-01-31 | Commonwealth Scientific And Industrial Research Organisation | Methods and compositions for increasing tissue tropism of recombinant adenoviral vectors |
| US20100150959A1 (en) * | 2008-12-15 | 2010-06-17 | Vectogen Pty Ltd. | PCV 2-Based Methods and Compositions for the Treatment of Pigs |
| US8865182B2 (en) * | 2009-07-31 | 2014-10-21 | Paxvax, Inc. | Adenoviral-based vectors |
| RU2727847C2 (ru) * | 2016-05-12 | 2020-07-24 | Биоэппликейшнз Инк. | Растительная композиция для вакцинации против чумы свиней и способ ее приготовления |
| CN107267469B (zh) * | 2017-08-22 | 2020-06-16 | 广州医科大学附属第一医院 | 纤毛蛋白嵌合型重组人b型腺病毒及其制备方法 |
| CN112625095B (zh) * | 2021-01-13 | 2023-01-03 | 武汉科前生物股份有限公司 | 一种猪轮状病毒重组蛋白以及表达该蛋白的重组腺病毒和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7232899B2 (en) * | 1996-09-25 | 2007-06-19 | The Scripps Research Institute | Adenovirus vectors, packaging cell lines, compositions, and methods for preparation and use |
| AUPO856097A0 (en) * | 1997-08-14 | 1997-09-04 | Commonwealth Scientific And Industrial Research Organisation | Vector |
| US6492343B1 (en) * | 1998-04-15 | 2002-12-10 | University Of Saskatchewan | Porcine adenovirus type 3 genome |
| WO1999055365A1 (en) | 1998-04-30 | 1999-11-04 | Cornell Research Foundation, Inc. | Adenoviral vectors with tandem fiber proteins |
| EP1191105A1 (en) | 2000-09-25 | 2002-03-27 | Galapagos Genomics B.V. | Gene delivery vectors provided with a tissue tropism for T-lymphocytes |
| AU6368901A (en) | 2000-05-31 | 2001-12-11 | Univ Saskatchewan | Modified bovine adenovirus having altered tropism |
| US20030219899A1 (en) * | 2001-04-17 | 2003-11-27 | Nikolay Korokhov | Mosaic adenoviral vectors |
| CA2658805A1 (en) * | 2006-07-28 | 2008-01-31 | Commonwealth Scientific And Industrial Research Organisation | Methods and compositions for increasing tissue tropism of recombinant adenoviral vectors |
-
2007
- 2007-07-27 CA CA002658805A patent/CA2658805A1/en not_active Abandoned
- 2007-07-27 CN CN200780026689A patent/CN101849012A/zh active Pending
- 2007-07-27 US US12/373,772 patent/US8163544B2/en not_active Expired - Fee Related
- 2007-07-27 MX MX2009000898A patent/MX2009000898A/es unknown
- 2007-07-27 AU AU2007278887A patent/AU2007278887A1/en not_active Abandoned
- 2007-07-27 JP JP2009521375A patent/JP2009544303A/ja active Pending
- 2007-07-27 KR KR1020097003405A patent/KR20090038910A/ko not_active Withdrawn
- 2007-07-27 EP EP07804942A patent/EP2059602A4/en not_active Withdrawn
- 2007-07-27 WO PCT/IB2007/002710 patent/WO2008012682A2/en not_active Ceased
- 2007-07-27 BR BRPI0714932-8A patent/BRPI0714932A2/pt not_active IP Right Cessation
- 2007-07-30 TW TW096127865A patent/TW200829273A/zh unknown
- 2007-07-30 AR ARP070103361A patent/AR062145A1/es unknown
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