JP2014533491A5 - - Google Patents
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- Publication number
- JP2014533491A5 JP2014533491A5 JP2014521869A JP2014521869A JP2014533491A5 JP 2014533491 A5 JP2014533491 A5 JP 2014533491A5 JP 2014521869 A JP2014521869 A JP 2014521869A JP 2014521869 A JP2014521869 A JP 2014521869A JP 2014533491 A5 JP2014533491 A5 JP 2014533491A5
- Authority
- JP
- Japan
- Prior art keywords
- pluripotent stem
- myf5
- myod
- stem cells
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000001778 pluripotent stem cell Anatomy 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 102100038380 Myogenic factor 5 Human genes 0.000 claims 5
- 101710099061 Myogenic factor 5 Proteins 0.000 claims 5
- 101001023030 Toxoplasma gondii Myosin-D Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 238000012258 culturing Methods 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 3
- 210000002363 skeletal muscle cell Anatomy 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 102100024785 Fibroblast growth factor 2 Human genes 0.000 claims 1
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 1
- 208000021642 Muscular disease Diseases 0.000 claims 1
- 201000009623 Myopathy Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 210000002242 embryoid body Anatomy 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000004043 responsiveness Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161561586P | 2011-11-18 | 2011-11-18 | |
| US61/561,586 | 2011-11-18 | ||
| PCT/JP2012/071373 WO2013073246A1 (en) | 2011-11-18 | 2012-08-17 | Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533491A JP2014533491A (ja) | 2014-12-15 |
| JP2014533491A5 true JP2014533491A5 (enExample) | 2015-10-08 |
| JP6083877B2 JP6083877B2 (ja) | 2017-02-22 |
Family
ID=48429327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014521869A Active JP6083877B2 (ja) | 2011-11-18 | 2012-08-17 | 多能性幹細胞から骨格筋細胞への分化誘導方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US9862929B2 (enExample) |
| JP (1) | JP6083877B2 (enExample) |
| WO (1) | WO2013073246A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6566520B2 (ja) * | 2013-10-29 | 2019-08-28 | 国立大学法人 熊本大学 | 筋疾患の治療または予防のための医薬組成物 |
| JP6728049B2 (ja) * | 2013-10-30 | 2020-07-22 | ザ キュレイターズ オブ ザ ユニバーシティ オブ ミズーリ | 拡張性のある骨格筋系譜形成及び培養の方法 |
| JP6845500B2 (ja) * | 2014-12-29 | 2021-03-17 | 国立大学法人京都大学 | 骨格筋前駆細胞の製造方法 |
| EP3246398B1 (en) * | 2015-01-14 | 2021-06-16 | Kyoto University | Method for selecting skeletal muscle progenitor cell |
| MX2017011345A (es) | 2015-03-03 | 2018-04-24 | Univ Minnesota | Gen de variante ets2 etv2 y usos del mismo. |
| JP2018523999A (ja) | 2015-06-30 | 2018-08-30 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | ヒト化心筋 |
| JP2018522553A (ja) * | 2015-06-30 | 2018-08-16 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | ヒト化骨格筋 |
| HK1252090A1 (zh) * | 2015-08-31 | 2019-05-17 | 爱平世股份有限公司 | 多能干细胞制造系统和生产诱导多能干细胞的方法 |
| WO2017131238A1 (ja) | 2016-01-31 | 2017-08-03 | 学校法人慶應義塾 | 未分化性低減による多能性幹細胞の分化促進法 |
| US20190161731A1 (en) * | 2016-04-06 | 2019-05-30 | The General Hospital Corporation | Direct reprogramming of somatic cells into myogenic cells |
| JP7090544B2 (ja) * | 2016-04-27 | 2022-06-24 | 武田薬品工業株式会社 | 骨格筋前駆細胞及び骨格筋細胞の製造方法 |
| CA3044691A1 (en) | 2016-10-26 | 2018-05-03 | Genea Biocells USA (Holdings), Inc. | Improved generation of muscle lineage cells and therapeutic uses thereof |
| JP2018143239A (ja) | 2017-03-01 | 2018-09-20 | エリクサジェン，エルエルシー． | 多能性幹細胞を所望の細胞型へ効率的に分化する方法 |
| EP3612623B1 (en) | 2017-05-06 | 2024-07-03 | Upside Foods, Inc. | Compositions and methods for increasing the culture density of a cellular biomass within a cultivation infrastructure |
| EP3638777A4 (en) | 2017-07-13 | 2021-05-12 | Memphis Meats, Inc. | COMPOSITIONS AND METHODS FOR INCREASING THE EFFICIENCY OF CELL CULTURES FOR FOOD MANUFACTURING |
| WO2020090836A1 (ja) * | 2018-10-30 | 2020-05-07 | 国立大学法人京都大学 | 細胞の製造方法 |
| WO2020204149A1 (ja) | 2019-03-29 | 2020-10-08 | 公立大学法人横浜市立大学 | スクリーニング方法および毒性評価法 |
| US20240018479A1 (en) * | 2020-10-26 | 2024-01-18 | University Of Massachusetts | Methods and compositions for treatment of muscle disease with ipsc-induced human skeletal muscle stem cells |
| CN112430624B (zh) * | 2020-11-25 | 2023-08-18 | 汕头大学 | 一种斑马鱼肌肉特异诱导型表达载体及应用 |
| US20240002806A1 (en) * | 2022-03-10 | 2024-01-04 | Innocent Meat GmbH | Method for differentiating adult stem cells into final tissue |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6432711B1 (en) * | 1993-11-03 | 2002-08-13 | Diacrin, Inc. | Embryonic stem cells capable of differentiating into desired cell lines |
| US6201168B1 (en) * | 1999-08-20 | 2001-03-13 | University Of Iowa Research Foundation | Pathogenesis of cardiomyopathy |
| JPWO2010008100A1 (ja) | 2008-07-17 | 2012-01-05 | 国立大学法人名古屋大学 | 骨格筋細胞又は骨細胞の誘導法 |
-
2012
- 2012-08-17 US US14/357,982 patent/US9862929B2/en active Active
- 2012-08-17 JP JP2014521869A patent/JP6083877B2/ja active Active
- 2012-08-17 WO PCT/JP2012/071373 patent/WO2013073246A1/en not_active Ceased
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