JP2014533491A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014533491A5 JP2014533491A5 JP2014521869A JP2014521869A JP2014533491A5 JP 2014533491 A5 JP2014533491 A5 JP 2014533491A5 JP 2014521869 A JP2014521869 A JP 2014521869A JP 2014521869 A JP2014521869 A JP 2014521869A JP 2014533491 A5 JP2014533491 A5 JP 2014533491A5
- Authority
- JP
- Japan
- Prior art keywords
- pluripotent stem
- myf5
- myod
- stem cells
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001778 pluripotent stem cell Anatomy 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 102100038380 Myogenic factor 5 Human genes 0.000 claims 5
- 101710099061 Myogenic factor 5 Proteins 0.000 claims 5
- 101001023030 Toxoplasma gondii Myosin-D Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 238000012258 culturing Methods 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 3
- 210000002363 skeletal muscle cell Anatomy 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 102100024785 Fibroblast growth factor 2 Human genes 0.000 claims 1
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 1
- 208000021642 Muscular disease Diseases 0.000 claims 1
- 201000009623 Myopathy Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 210000002242 embryoid body Anatomy 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000004043 responsiveness Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161561586P | 2011-11-18 | 2011-11-18 | |
| US61/561,586 | 2011-11-18 | ||
| PCT/JP2012/071373 WO2013073246A1 (en) | 2011-11-18 | 2012-08-17 | Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533491A JP2014533491A (ja) | 2014-12-15 |
| JP2014533491A5 true JP2014533491A5 (enExample) | 2015-10-08 |
| JP6083877B2 JP6083877B2 (ja) | 2017-02-22 |
Family
ID=48429327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014521869A Active JP6083877B2 (ja) | 2011-11-18 | 2012-08-17 | 多能性幹細胞から骨格筋細胞への分化誘導方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US9862929B2 (enExample) |
| JP (1) | JP6083877B2 (enExample) |
| WO (1) | WO2013073246A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6566520B2 (ja) * | 2013-10-29 | 2019-08-28 | 国立大学法人 熊本大学 | 筋疾患の治療または予防のための医薬組成物 |
| US20160251625A1 (en) * | 2013-10-30 | 2016-09-01 | The Curators Of The University Of Missouri | Method for scalable skeletal muscle lineage specification and cultivation |
| JP6845500B2 (ja) * | 2014-12-29 | 2021-03-17 | 国立大学法人京都大学 | 骨格筋前駆細胞の製造方法 |
| JP6883791B2 (ja) * | 2015-01-14 | 2021-06-09 | 国立大学法人京都大学 | 骨格筋前駆細胞の選択方法 |
| WO2016141234A1 (en) | 2015-03-03 | 2016-09-09 | Regents Of The University Of Minnesota | Etv2 and uses thereof |
| CN108472318A (zh) | 2015-06-30 | 2018-08-31 | 明尼苏达大学校董会 | 人源化心脏肌肉 |
| US10874092B2 (en) | 2015-06-30 | 2020-12-29 | Regents Of The University Of Minnesota | Humanized skeletal muscle |
| HK1252090A1 (zh) * | 2015-08-31 | 2019-05-17 | 爱平世股份有限公司 | 多能干细胞制造系统和生产诱导多能干细胞的方法 |
| US11396644B2 (en) | 2016-01-31 | 2022-07-26 | Keio University | Method for promoting differentiation of pluripotent stem cells by reducing undifferentiated state thereof |
| US20190161731A1 (en) * | 2016-04-06 | 2019-05-30 | The General Hospital Corporation | Direct reprogramming of somatic cells into myogenic cells |
| JP7090544B2 (ja) * | 2016-04-27 | 2022-06-24 | 武田薬品工業株式会社 | 骨格筋前駆細胞及び骨格筋細胞の製造方法 |
| CA3044691A1 (en) | 2016-10-26 | 2018-05-03 | Genea Biocells USA (Holdings), Inc. | Improved generation of muscle lineage cells and therapeutic uses thereof |
| US11136555B2 (en) * | 2017-03-01 | 2021-10-05 | Elixirgen Scientific, Inc. | Compositions and methods for differentiation of human pluripotent stem cells into desired cell types |
| ES2985769T3 (es) | 2017-05-06 | 2024-11-07 | Upside Foods Inc | Composiciones y métodos para aumentar la densidad de cultivo de una biomasa celular dentro de una infraestructura de cultivo |
| US11479792B2 (en) | 2017-07-13 | 2022-10-25 | Upside Foods, Inc. | Compositions and methods for increasing the efficiency of cell cultures used for food production |
| JP7548494B2 (ja) * | 2018-10-30 | 2024-09-10 | 国立大学法人京都大学 | 細胞の製造方法 |
| JP7533896B2 (ja) | 2019-03-29 | 2024-08-14 | 公立大学法人横浜市立大学 | スクリーニング方法および毒性評価法 |
| EP4232563A4 (en) * | 2020-10-26 | 2024-12-04 | University of Massachusetts | METHODS AND COMPOSITIONS FOR TREATING MUSCLE DISEASES WITH IPSC-INDUCED HUMAN SKELETAL MUSCLE STEM CELLS |
| CN112430624B (zh) * | 2020-11-25 | 2023-08-18 | 汕头大学 | 一种斑马鱼肌肉特异诱导型表达载体及应用 |
| US20240002806A1 (en) * | 2022-03-10 | 2024-01-04 | Innocent Meat GmbH | Method for differentiating adult stem cells into final tissue |
| WO2023240152A1 (en) | 2022-06-07 | 2023-12-14 | Upside Foods, Inc. | Engineering cell lines capable of proliferation in growth factor free media formulations |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6432711B1 (en) * | 1993-11-03 | 2002-08-13 | Diacrin, Inc. | Embryonic stem cells capable of differentiating into desired cell lines |
| US6201168B1 (en) * | 1999-08-20 | 2001-03-13 | University Of Iowa Research Foundation | Pathogenesis of cardiomyopathy |
| WO2010008100A1 (ja) * | 2008-07-17 | 2010-01-21 | 国立大学法人名古屋大学 | 骨格筋細胞又は骨細胞の誘導法 |
-
2012
- 2012-08-17 US US14/357,982 patent/US9862929B2/en active Active
- 2012-08-17 WO PCT/JP2012/071373 patent/WO2013073246A1/en not_active Ceased
- 2012-08-17 JP JP2014521869A patent/JP6083877B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Scalise et al. | From spheroids to organoids: the next generation of model systems of human cardiac regeneration in a dish | |
| Barreto et al. | Cardiac progenitor cells from stem cells: learning from genetics and biomaterials | |
| JP2018508198A5 (enExample) | ||
| JP2015165823A5 (enExample) | ||
| BR112015022770A8 (pt) | meio e sistema de cultivo da célula livre de xenógeno, livre de albumina, forma concentrada, métodos de diferenciação de células-tronco pluripotentes humanas, para a produção de mesenquimoangioblastos e sistema definido de cultivo da célula para diferenciação hematoendotelial das células- tronco pluripotentes humanas | |
| BR112015019950A2 (pt) | Método para gerar linhagem de células-tronco embrionárias (es) de rato, e, cultura in vitro | |
| NZ745940A (en) | Methods for providing single-stranded rna | |
| CA2821065C (en) | Culture method to obtain and maintain a pure or enriched population of mammalian neural stem cells and/or neural progenitor cells that are prone to differentiate into oligodendrocyte-lineage cells in vitro | |
| MX363017B (es) | Métodos y productos para la expresión de proteínas en células. | |
| MX2021000211A (es) | Metodos y productos para transfeccion de celulas. | |
| MY151979A (en) | Method for producing mesenchymal stem cells from human pluripotent stem cells, and mesenchymal stem cells produced by same | |
| WO2015120096A3 (en) | Methods for producing autologous t cells useful to treat b cell malignancies and other cancers and compositions thereof | |
| JP2016500260A5 (enExample) | ||
| MX2012007117A (es) | Metodo para cultivar celulas adherentes. | |
| HK1212148A2 (en) | A method for the isolation and cultivation of mesenchymal stem cells from umbilical cords, and a method for the differentiation of the umbilical cord-derived mesenchymal stem cells into various mesenchymal tissues | |
| EP3369810A4 (en) | METHOD FOR PRODUCING CELL POPULATION WITH MESENCHYMAL STEM CELLS, MESENCHYMAL STEM CELLS, CELL POPULATION AND PHARMACEUTICAL COMPOSITION | |
| JP2017500013A5 (enExample) | ||
| JP2012532585A5 (enExample) | ||
| RU2014143979A (ru) | Пригодные для использования в пищу бактерии lactobacillus rhamnosus | |
| JP2015159895A5 (enExample) | ||
| MX2012006759A (es) | Tejido adiposo descelularizado. | |
| JP2018529389A5 (enExample) | ||
| WO2015073625A3 (en) | Synergistic genome-nonintegrating reprogramming by micrornas and transcription factors | |
| WO2015108944A3 (en) | Stem cell-derived hepatocytes in co-culture and uses thereof | |
| JP2012143229A5 (enExample) |