JP2013539032A - ライム病の診断方法 - Google Patents

ライム病の診断方法 Download PDF

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Publication number
JP2013539032A
JP2013539032A JP2013530408A JP2013530408A JP2013539032A JP 2013539032 A JP2013539032 A JP 2013539032A JP 2013530408 A JP2013530408 A JP 2013530408A JP 2013530408 A JP2013530408 A JP 2013530408A JP 2013539032 A JP2013539032 A JP 2013539032A
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Prior art keywords
lyme disease
antibodies
ospc
ospf
ospa
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JP2013530408A
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Japanese (ja)
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JP2013539032A5 (https=
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ヴァグナー，ベッティーナ
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Cornell University
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Cornell University
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Publication of JP2013539032A5 publication Critical patent/JP2013539032A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2013530408A 2010-09-27 2011-09-27 ライム病の診断方法 Pending JP2013539032A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38669410P 2010-09-27 2010-09-27
US61/386,694 2010-09-27
PCT/US2011/053359 WO2012047607A2 (en) 2010-09-27 2011-09-27 Methods for diagnosing lyme disease

Publications (2)

Publication Number Publication Date
JP2013539032A true JP2013539032A (ja) 2013-10-17
JP2013539032A5 JP2013539032A5 (https=) 2014-11-20

Family

ID=45928310

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013530408A Pending JP2013539032A (ja) 2010-09-27 2011-09-27 ライム病の診断方法

Country Status (11)

Country Link
US (1) US8946393B2 (https=)
EP (1) EP2622346A4 (https=)
JP (1) JP2013539032A (https=)
KR (1) KR20130101067A (https=)
CN (1) CN103229055A (https=)
BR (1) BR112013007329A2 (https=)
CA (1) CA2812759A1 (https=)
MX (1) MX2013003609A (https=)
RU (1) RU2013118647A (https=)
WO (1) WO2012047607A2 (https=)
ZA (1) ZA201302402B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018536429A (ja) * 2015-09-25 2018-12-13 キアゲン サイエンシス リミテッド ライアビリティ カンパニー ライム病を診断するためのおよび治療後のライム病スピロヘータ除去を予測するための組成物および方法

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PT106942B (pt) 2013-05-15 2020-09-10 STAB VIDA, Investigação e Serviços em Ciências Biológicas, Lda Biochip (1) e bouquet de 16 antigénios (2) para a deteção da doença de lyme aguda e crónica
EP4108256A1 (en) * 2014-08-11 2022-12-28 University of Massachusetts Anti-ospa antibodies and methods of use
CN104374921B (zh) * 2014-11-21 2016-09-07 安徽医科大学 一种用于莱姆病鞭毛抗原免疫血清学诊断的蛋白质芯片及其制备方法和应用
CN105524989A (zh) * 2015-12-31 2016-04-27 中国疾病预防控制中心传染病预防控制所 用于检测莱姆病螺旋体的rpa引物和探针及检测方法
CN105628918A (zh) * 2016-02-04 2016-06-01 浙江大学 一种蜱传莱姆病伯氏疏螺旋体检测试剂及应用
CA3114668A1 (en) * 2018-10-01 2020-04-09 The Board Of Trustees Of The Leland Stanford Junior University High specificity and sensitivity immunosorbent diagnostic assays with simultaneous resolution of multiple antibody isotypes
CA3164344A1 (en) * 2020-01-10 2021-07-15 Samantha Chang Test strip with structured substrate for multiplex lateral flow assay for disease diagnostics
CA3175297A1 (en) 2020-04-13 2021-10-21 Jyotsna Shah Detection of lyme disease
US20230324382A1 (en) * 2022-02-01 2023-10-12 Trustees Of Tufts College Antiphospholipid antibodies for the diagnosis of lyme disease

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US6143872A (en) * 1988-10-24 2000-11-07 Symbicom Aktiebolag Borrelia burdorferi Osp A and B proteins and immunogenic peptides
US5777095A (en) * 1988-10-24 1998-07-07 Symbicom Aktiebolag Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90
US6300101B1 (en) 1988-10-24 2001-10-09 Board Of Regents, The University Of Texas System Methods and compositions including a 13kD B. burgdorferi protein
US6872550B1 (en) * 1991-07-11 2005-03-29 Baxter Vaccine Ag Immunogenic formulation of OspC antigen vaccines for the prevention and treatment of lyme disease and recombinant methods for the preparation of such antigens
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018536429A (ja) * 2015-09-25 2018-12-13 キアゲン サイエンシス リミテッド ライアビリティ カンパニー ライム病を診断するためのおよび治療後のライム病スピロヘータ除去を予測するための組成物および方法
US10983121B2 (en) 2015-09-25 2021-04-20 Qiagen Sciences Llc Compositions and methods for diagnosing Lyme disease and for predicting Lyme disease spirochete elimination after treatment
US12066436B2 (en) 2015-09-25 2024-08-20 Qiagen Sciences Llc Compositions and methods for diagnosing Lyme disease and for predicting Lyme disease spirochete elimination after treatment

Also Published As

Publication number Publication date
WO2012047607A3 (en) 2012-08-16
KR20130101067A (ko) 2013-09-12
RU2013118647A (ru) 2014-11-10
MX2013003609A (es) 2013-10-17
EP2622346A4 (en) 2014-04-16
US8946393B2 (en) 2015-02-03
US20130273572A1 (en) 2013-10-17
BR112013007329A2 (pt) 2016-07-19
WO2012047607A2 (en) 2012-04-12
CA2812759A1 (en) 2012-04-12
CN103229055A (zh) 2013-07-31
EP2622346A2 (en) 2013-08-07
ZA201302402B (en) 2014-06-25

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