CN103229055A - 莱姆病的诊断方法 - Google Patents

莱姆病的诊断方法 Download PDF

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Publication number
CN103229055A
CN103229055A CN2011800562501A CN201180056250A CN103229055A CN 103229055 A CN103229055 A CN 103229055A CN 2011800562501 A CN2011800562501 A CN 2011800562501A CN 201180056250 A CN201180056250 A CN 201180056250A CN 103229055 A CN103229055 A CN 103229055A
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ospc
ospf
antibody
ospa
mammal
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Chinese (zh)
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B·瓦格纳
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Cornell University
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Cornell University
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN2011800562501A 2010-09-27 2011-09-27 莱姆病的诊断方法 Pending CN103229055A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38669410P 2010-09-27 2010-09-27
US61/386,694 2010-09-27
PCT/US2011/053359 WO2012047607A2 (en) 2010-09-27 2011-09-27 Methods for diagnosing lyme disease

Publications (1)

Publication Number Publication Date
CN103229055A true CN103229055A (zh) 2013-07-31

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CN2011800562501A Pending CN103229055A (zh) 2010-09-27 2011-09-27 莱姆病的诊断方法

Country Status (11)

Country Link
US (1) US8946393B2 (https=)
EP (1) EP2622346A4 (https=)
JP (1) JP2013539032A (https=)
KR (1) KR20130101067A (https=)
CN (1) CN103229055A (https=)
BR (1) BR112013007329A2 (https=)
CA (1) CA2812759A1 (https=)
MX (1) MX2013003609A (https=)
RU (1) RU2013118647A (https=)
WO (1) WO2012047607A2 (https=)
ZA (1) ZA201302402B (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104374921A (zh) * 2014-11-21 2015-02-25 安徽医科大学 一种用于莱姆病鞭毛抗原免疫血清学诊断的蛋白质芯片及其制备方法和应用
CN105524989A (zh) * 2015-12-31 2016-04-27 中国疾病预防控制中心传染病预防控制所 用于检测莱姆病螺旋体的rpa引物和探针及检测方法
CN105628918A (zh) * 2016-02-04 2016-06-01 浙江大学 一种蜱传莱姆病伯氏疏螺旋体检测试剂及应用
CN113302493A (zh) * 2018-10-01 2021-08-24 小利兰·斯坦福大学托管委员会 同时解析多种抗体同种型的高特异性和灵敏度免疫吸附诊断测定

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT106942B (pt) 2013-05-15 2020-09-10 STAB VIDA, Investigação e Serviços em Ciências Biológicas, Lda Biochip (1) e bouquet de 16 antigénios (2) para a deteção da doença de lyme aguda e crónica
EP4108256A1 (en) * 2014-08-11 2022-12-28 University of Massachusetts Anti-ospa antibodies and methods of use
CN108139401B (zh) 2015-09-25 2022-02-18 凯杰科技有限公司 诊断莱姆病并用于预测治疗后莱姆病螺旋体消除的组合物和方法
CA3164344A1 (en) * 2020-01-10 2021-07-15 Samantha Chang Test strip with structured substrate for multiplex lateral flow assay for disease diagnostics
CA3175297A1 (en) 2020-04-13 2021-10-21 Jyotsna Shah Detection of lyme disease
US20230324382A1 (en) * 2022-02-01 2023-10-12 Trustees Of Tufts College Antiphospholipid antibodies for the diagnosis of lyme disease

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CN1159831A (zh) * 1994-08-17 1997-09-17 马克斯·普朗克促进科学协会 含有布氏疏螺旋体ospg的疫苗
CN101374858A (zh) * 2005-11-29 2009-02-25 弗吉尼亚州立大学 多价嵌合ospc疫苗原及诊断抗原
US7794727B2 (en) * 2005-11-29 2010-09-14 Virginia Commonwealth University Polyvalent chimeric OspC vaccinogen and diagnostic antigen

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104374921A (zh) * 2014-11-21 2015-02-25 安徽医科大学 一种用于莱姆病鞭毛抗原免疫血清学诊断的蛋白质芯片及其制备方法和应用
CN105524989A (zh) * 2015-12-31 2016-04-27 中国疾病预防控制中心传染病预防控制所 用于检测莱姆病螺旋体的rpa引物和探针及检测方法
CN105628918A (zh) * 2016-02-04 2016-06-01 浙江大学 一种蜱传莱姆病伯氏疏螺旋体检测试剂及应用
CN113302493A (zh) * 2018-10-01 2021-08-24 小利兰·斯坦福大学托管委员会 同时解析多种抗体同种型的高特异性和灵敏度免疫吸附诊断测定

Also Published As

Publication number Publication date
WO2012047607A3 (en) 2012-08-16
KR20130101067A (ko) 2013-09-12
RU2013118647A (ru) 2014-11-10
MX2013003609A (es) 2013-10-17
JP2013539032A (ja) 2013-10-17
EP2622346A4 (en) 2014-04-16
US8946393B2 (en) 2015-02-03
US20130273572A1 (en) 2013-10-17
BR112013007329A2 (pt) 2016-07-19
WO2012047607A2 (en) 2012-04-12
CA2812759A1 (en) 2012-04-12
EP2622346A2 (en) 2013-08-07
ZA201302402B (en) 2014-06-25

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Application publication date: 20130731