DE69912827T2 - "ligand presenting assembly" (lpa), verfahren zu dessen herstellung und verwendungen - Google Patents

"ligand presenting assembly" (lpa), verfahren zu dessen herstellung und verwendungen Download PDF

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Publication number
DE69912827T2
DE69912827T2 DE69912827T DE69912827T DE69912827T2 DE 69912827 T2 DE69912827 T2 DE 69912827T2 DE 69912827 T DE69912827 T DE 69912827T DE 69912827 T DE69912827 T DE 69912827T DE 69912827 T2 DE69912827 T2 DE 69912827T2
Authority
DE
Germany
Prior art keywords
lpa
production
presenting assembly
ligand presenting
ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69912827T
Other languages
English (en)
Other versions
DE69912827D1 (de
Inventor
Arne Holm
Malene Jorgensen
Soren Ostergaard
Michael Theisen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOKE DIAGNOSTICS APS, AARHUS, DK
Original Assignee
LOKE DIAGNOSTICS APS AARHUS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOKE DIAGNOSTICS APS AARHUS filed Critical LOKE DIAGNOSTICS APS AARHUS
Application granted granted Critical
Publication of DE69912827D1 publication Critical patent/DE69912827D1/de
Publication of DE69912827T2 publication Critical patent/DE69912827T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02Linear peptides containing at least one abnormal peptide link
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/64Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • A61K2039/645Dendrimers; Multiple antigen peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Analytical Chemistry (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Liquid Crystal Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69912827T 1998-09-29 1999-09-29 "ligand presenting assembly" (lpa), verfahren zu dessen herstellung und verwendungen Expired - Lifetime DE69912827T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199801233 1998-09-29
PCT/DK1999/000510 WO2000018791A1 (en) 1998-09-29 1999-09-29 Ligand presenting assembly (lpa), method of preparation and uses thereof

Publications (2)

Publication Number Publication Date
DE69912827D1 DE69912827D1 (de) 2003-12-18
DE69912827T2 true DE69912827T2 (de) 2004-10-21

Family

ID=8102501

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69912827T Expired - Lifetime DE69912827T2 (de) 1998-09-29 1999-09-29 "ligand presenting assembly" (lpa), verfahren zu dessen herstellung und verwendungen

Country Status (6)

Country Link
US (1) US20040086949A1 (de)
EP (1) EP1117677B1 (de)
AT (1) ATE254137T1 (de)
AU (1) AU6078399A (de)
DE (1) DE69912827T2 (de)
WO (1) WO2000018791A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040242479A1 (en) 2001-08-17 2004-12-02 Elisabeth Bock Compounds capable of affecting differentiation, proliferation, regeneration, plasticity and survival of cells
DE602004027508D1 (de) * 2003-08-07 2010-07-15 Enkam Pharmaceuticals As Lpa-haltige verbindungen
US20070172496A1 (en) * 2004-01-28 2007-07-26 Curix Aps Conjugates of amyloid proteins as vaccines for amyloid-related diseases
EP2377884A1 (de) 2005-05-10 2011-10-19 Neoloch Aps Neuritogene peptide
US8618060B2 (en) 2006-02-14 2013-12-31 University Of Tasmania Metallothionein-derived peptide fragments
US20090285780A1 (en) * 2006-05-24 2009-11-19 Chyi Lee Peg linker compounds and biologically active conjugates thereof
EP2164992B1 (de) * 2007-05-30 2016-05-04 Lpath, Inc. Zusammensetzungen und verfahren zur bindung von lysophosphatidinsäure
US8470964B2 (en) 2007-11-28 2013-06-25 Enkam Pharmaceuticals A/S Peptides derived from NCAM (FGLs)
CN103229055A (zh) * 2010-09-27 2013-07-31 康奈尔大学 莱姆病的诊断方法
WO2014093196A1 (en) * 2012-12-10 2014-06-19 North Carolina State University Solid phase scaffold based libraries
WO2014147129A1 (en) * 2013-03-21 2014-09-25 Sanofi-Aventis Deutschland Gmbh Synthesis of cyclic imide containing peptide products

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596792A (en) * 1981-09-04 1986-06-24 The Regents Of The University Of California Safe vaccine for hepatitis containing polymerized serum albumin
US4599230A (en) * 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US4599231A (en) * 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US4608251A (en) * 1984-11-09 1986-08-26 Pitman-Moore, Inc. LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues
US4601903A (en) * 1985-05-01 1986-07-22 The United States Of America As Represented By The Department Of Health And Human Services Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease
GB9215780D0 (en) * 1992-07-24 1992-09-09 Univ London Pharmacy Peptide compounds
DE69718903T2 (de) * 1996-05-02 2003-12-04 Dakocytomation Denmark As Glos Verwendung von aus osp-c abgeleiteten peptidefragmenten für diagnostische methoden
CA2278200A1 (en) * 1997-01-29 1998-07-30 Nycomed Imaging As Polymers

Also Published As

Publication number Publication date
ATE254137T1 (de) 2003-11-15
EP1117677A1 (de) 2001-07-25
WO2000018791A1 (en) 2000-04-06
AU6078399A (en) 2000-04-17
DE69912827D1 (de) 2003-12-18
EP1117677B1 (de) 2003-11-12
US20040086949A1 (en) 2004-05-06

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Legal Events

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8327 Change in the person/name/address of the patent owner

Owner name: LOKE DIAGNOSTICS APS, AARHUS, DK

8364 No opposition during term of opposition