JP2013526366A - 薬物送達装置 - Google Patents
薬物送達装置 Download PDFInfo
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- JP2013526366A JP2013526366A JP2013511159A JP2013511159A JP2013526366A JP 2013526366 A JP2013526366 A JP 2013526366A JP 2013511159 A JP2013511159 A JP 2013511159A JP 2013511159 A JP2013511159 A JP 2013511159A JP 2013526366 A JP2013526366 A JP 2013526366A
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- 238000012377 drug delivery Methods 0.000 title claims abstract description 56
- 239000003814 drug Substances 0.000 claims abstract description 31
- 229940079593 drug Drugs 0.000 claims abstract description 26
- 238000003780 insertion Methods 0.000 claims abstract description 4
- 230000037431 insertion Effects 0.000 claims abstract description 4
- 230000004913 activation Effects 0.000 claims description 15
- 238000004891 communication Methods 0.000 claims description 9
- 239000000853 adhesive Substances 0.000 claims description 5
- 230000001070 adhesive effect Effects 0.000 claims description 5
- 230000000007 visual effect Effects 0.000 claims description 2
- 238000006073 displacement reaction Methods 0.000 abstract description 23
- 238000002347 injection Methods 0.000 abstract description 11
- 239000007924 injection Substances 0.000 abstract description 11
- 238000000034 method Methods 0.000 description 12
- 238000007789 sealing Methods 0.000 description 12
- 230000007246 mechanism Effects 0.000 description 8
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- 239000013013 elastic material Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000007769 metal material Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 239000012815 thermoplastic material Substances 0.000 description 2
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
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- 238000013459 approach Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
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- 230000004044 response Effects 0.000 description 1
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- 239000000126 substance Substances 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1413—Modular systems comprising interconnecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/3157—Means providing feedback signals when administration is completed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
- A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
- A61M2005/1426—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with means for preventing access to the needle after use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31515—Connection of piston with piston rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims (13)
- 薬剤を注入する薬物送達装置であって、前記薬物送達装置は、
薬剤を収容するチューブ状の貯留部であって、長手方向軸線に沿って延在している貯留部、
前記貯留部内に摺動可能に配置されているストッパー、
前記ストッパーを前記貯留部内で第1の位置から第2の位置へ移動させるスプリング、
少なくとも1つのニードルであって、前記ニードルは患者への挿入のための末端部、及び前記末端部から基端方向に延在している空腔であって、前記空腔は直接又は間接に前記貯留部に連通しており、前記末端部から基端方向に延在している前記空腔の少なくとも一部は前記長手方向軸線と同軸ではない基準の軸線に沿って延在している空腔を有している少なくとも1つのニードル、
前記ニードルを第1の状態から第2の状態へ変位させるニードル駆動器、及び
アクチュエーター、を備え、
前記アクチュエーターの活性化は、
前記スプリングが前記ストッパーを前記第1の位置から前記第2の位置に向けて移動させ、及び
前記ニードル駆動器が前記ニードルを前記第1の状態から前記第2の状態に向けて変位させることを生じさせ、
ここで、前記ニードルは、前記ニードルが前記第1の状態から前記第2の状態に向けて変位されている状態で、前記貯留部に対して及びそれとは別に移動することを特徴とする薬物送達装置。 - 前記ニードルの前記空腔に連通する流れのチャンネルであって、前記流れのチャンネルは前記貯留部に選択的に連通可能であり、及び初期状態においては、前記流れのチャンネルは前記貯留部に連通していない流れのチャンネルをさらに備えることを特徴とする請求項1に記載の薬物送達装置。
- 前記アクチュエーターの活性化が前記チャンネルの前記貯留部との連通を生じさせることを特徴とする請求項2に記載の薬物送達装置。
- 前記流れのチャンネル及び前記貯留部の間の選択的な連通を可能にする調節可能なバルブをさらに備えることを特徴とする請求項2に記載の薬物送達装置。
- 前記貯留部内に配置され、及び前記ストッパーから離間されている第2のストッパーをさらに備えることを特徴とする請求項1に記載の薬物送達装置。
- 前記流路に連通する空腔を有する少なくとも1つの二次的なニードルであって、前記二次的なニードルは基端部を有し、初期状態において、前記二次的なニードルの前記基端部は、前記第2のストッパーから離間されるか、又は前記第2のストッパー内に部分的に埋設され、及び、前記第2のストッパーは、前記二次的なニードルの前記基端部が前記貯留部に連通されるのを可能にすべく前記二次的なニードルによって貫通して穿刺されるように変位可能であることを特徴とする請求項5に記載の薬物送達装置。
- 注入器を患者へ取外し可能に粘着して固定する接着剤をさらに備えることを特徴とする請求項1に記載の薬物送達装置。
- 前記ニードル駆動器は片持ち梁のアームを含み、前記片持ち梁のアームの変形が前記ニードルの前記第1の状態から前記第2の状態へ向けての変位を生じさせることを特徴とする請求項1に記載の薬物送達装置。
- 前記ニードル駆動器は、前記片持ち梁のアームの変形を生じさせるスプリングをさらに含むことを特徴とする請求項8に記載の薬物送達装置。
- 前記ストッパーが前記第2の位置に移動したことを指示する指示器をさらに備えることを特徴とする請求項1に記載の薬物送達装置。
- 前記貯留部が内部に収容される本体をさらに備え、窓が、前記貯留部の少なくとも一部の視認を可能にするべく、前記本体に形成されていることを特徴とする請求項1に記載の薬物送達装置。
- 前記貯留部が内部に収容される本体をさらに備え、前記第1の状態において、前記ニードルの前記末端部は前記本体内にあり、及び前記第2の状態において、前記ニードルの前記末端部は前記本体の外に露出されることを特徴とする請求項1に記載の薬物送達装置。
- 前記長手方向軸線に平行でないことを特徴とする請求項1に記載の薬物送達装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34654210P | 2010-05-20 | 2010-05-20 | |
US61/346,542 | 2010-05-20 | ||
PCT/US2011/030182 WO2011146166A1 (en) | 2010-05-20 | 2011-03-28 | Drug delivery device |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015257430A Division JP6141400B2 (ja) | 2010-05-20 | 2015-12-28 | 薬物送達装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013526366A true JP2013526366A (ja) | 2013-06-24 |
JP5934188B2 JP5934188B2 (ja) | 2016-06-15 |
Family
ID=44359824
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013511159A Active JP5934188B2 (ja) | 2010-05-20 | 2011-03-28 | 薬物送達装置 |
JP2015257430A Active JP6141400B2 (ja) | 2010-05-20 | 2015-12-28 | 薬物送達装置 |
JP2017091851A Active JP6454751B2 (ja) | 2010-05-20 | 2017-05-02 | 薬物送達装置 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015257430A Active JP6141400B2 (ja) | 2010-05-20 | 2015-12-28 | 薬物送達装置 |
JP2017091851A Active JP6454751B2 (ja) | 2010-05-20 | 2017-05-02 | 薬物送達装置 |
Country Status (12)
Country | Link |
---|---|
US (5) | US9408985B2 (ja) |
EP (6) | EP3028726B1 (ja) |
JP (3) | JP5934188B2 (ja) |
CN (2) | CN102971027B (ja) |
AU (1) | AU2011256804B2 (ja) |
BR (1) | BR112012029642B1 (ja) |
CA (2) | CA2799721C (ja) |
DK (3) | DK3028726T3 (ja) |
ES (5) | ES2859665T3 (ja) |
MX (6) | MX369242B (ja) |
SG (5) | SG10202001055YA (ja) |
WO (1) | WO2011146166A1 (ja) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015102078A1 (ja) * | 2014-01-06 | 2015-07-09 | 大研医器株式会社 | 輸液セット及びその駆動を制御する制御装置並びにこれらを備えた薬液送り機能付き輸液セット |
JP2019504710A (ja) * | 2016-02-12 | 2019-02-21 | ペルキュフロー, エルエルシー | 携行用注入ポンプおよびそれとの使用のためのアセンブリ |
JP2019528945A (ja) * | 2016-09-27 | 2019-10-17 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 薬剤送達デバイス |
JP2022009664A (ja) * | 2016-06-09 | 2022-01-14 | ベクトン・ディキンソン・アンド・カンパニー | 薬物送達システムのための駆動アセンブリ |
Families Citing this family (129)
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DK1762259T3 (da) | 2005-09-12 | 2011-01-03 | Unomedical As | Indføringsindretning til infusionssæt med en første og en anden fjederenhed |
US9656019B2 (en) | 2007-10-02 | 2017-05-23 | Medimop Medical Projects Ltd. | Apparatuses for securing components of a drug delivery system during transport and methods of using same |
US9345836B2 (en) | 2007-10-02 | 2016-05-24 | Medimop Medical Projects Ltd. | Disengagement resistant telescoping assembly and unidirectional method of assembly for such |
EP2195052B1 (en) | 2007-10-02 | 2019-09-04 | Medimop Medical Projects Ltd. | External drug pump |
US10420880B2 (en) | 2007-10-02 | 2019-09-24 | West Pharma. Services IL, Ltd. | Key for securing components of a drug delivery system during assembly and/or transport and methods of using same |
US7967795B1 (en) | 2010-01-19 | 2011-06-28 | Lamodel Ltd. | Cartridge interface assembly with driving plunger |
US8052645B2 (en) | 2008-07-23 | 2011-11-08 | Avant Medical Corp. | System and method for an injection using a syringe needle |
MX2010012691A (es) | 2008-05-20 | 2011-03-30 | Avant Medical Corp Star | Sistema auto-inyector. |
US9393369B2 (en) | 2008-09-15 | 2016-07-19 | Medimop Medical Projects Ltd. | Stabilized pen injector |
US10071196B2 (en) | 2012-05-15 | 2018-09-11 | West Pharma. Services IL, Ltd. | Method for selectively powering a battery-operated drug-delivery device and device therefor |
USD810279S1 (en) | 2009-09-15 | 2018-02-13 | Medimop Medical Projects Ltd. | Injector device |
US10071198B2 (en) | 2012-11-02 | 2018-09-11 | West Pharma. Servicees IL, Ltd. | Adhesive structure for medical device |
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