JP2013519699A - 因子ｖｉｉｉ融合タンパク質 - Google Patents
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- C07K—PEPTIDES
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| US30617710P | 2010-02-19 | 2010-02-19 | |
| US61/306,177 | 2010-02-19 | ||
| PCT/EP2011/051959 WO2011101284A1 (en) | 2010-02-16 | 2011-02-10 | Factor viii fusion protein |
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| JP2017144266A Withdrawn JP2017190342A (ja) | 2010-02-16 | 2017-07-26 | 因子ｖｉｉｉ融合タンパク質 |
Country Status (5)
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| US (2) | US9493543B2 (enExample) |
| EP (2) | EP2536754A1 (enExample) |
| JP (3) | JP2013519699A (enExample) |
| CN (2) | CN105153313A (enExample) |
| WO (1) | WO2011101284A1 (enExample) |
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| JP2017536105A (ja) * | 2014-10-17 | 2017-12-07 | コディアック サイエンシーズ インコーポレイテッドＫｏｄｉａｋ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． | ブチリルコリンエステラーゼ両性イオン性ポリマーコンジュゲート |
| JP2019502361A (ja) * | 2015-11-13 | 2019-01-31 | アステリオン・リミテッド | 成長ホルモン受容体の細胞外結合ドメインを含む融合ポリペプチド |
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| US8716448B2 (en) | 2009-02-03 | 2014-05-06 | Amunix Operating Inc. | Coagulation factor VII compositions and methods of making and using same |
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| CA3150442A1 (en) * | 2019-09-02 | 2021-03-11 | Biotest Ag | Factor viii protein with increased half-life |
| WO2021094344A1 (en) | 2019-11-11 | 2021-05-20 | CSL Behring Lengnau AG | Polypeptides for inducing tolerance to factor viii |
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| KR20250013211A (ko) * | 2022-05-25 | 2025-01-31 | 지앙수 젠사이언시스 아이엔씨. | 연장된 반감기를 갖는 fviii 융합 단백질 접합체 및 이의 용도 |
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| JP2017536105A (ja) * | 2014-10-17 | 2017-12-07 | コディアック サイエンシーズ インコーポレイテッドＫｏｄｉａｋ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． | ブチリルコリンエステラーゼ両性イオン性ポリマーコンジュゲート |
| JP2019502361A (ja) * | 2015-11-13 | 2019-01-31 | アステリオン・リミテッド | 成長ホルモン受容体の細胞外結合ドメインを含む融合ポリペプチド |
| US11066465B2 (en) | 2015-12-30 | 2021-07-20 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
| US12071476B2 (en) | 2018-03-02 | 2024-08-27 | Kodiak Sciences Inc. | IL-6 antibodies and fusion constructs and conjugates thereof |
| JP2021530437A (ja) * | 2018-05-18 | 2021-11-11 | 鄭州晟斯生物科技有限公司Zhengzhou Gensciences Inc | 改良されたｆｖｉｉｉ融合タンパク質及びその応用 |
| JP2023093634A (ja) * | 2018-05-18 | 2023-07-04 | 鄭州晟斯生物科技有限公司 | 改良されたｆｖｉｉｉ融合タンパク質及びその応用 |
| JP7492780B2 (ja) | 2018-05-18 | 2024-05-30 | 鄭州晟斯生物科技有限公司 | 改良されたｆｖｉｉｉ融合タンパク質及びその応用 |
| US11912784B2 (en) | 2019-10-10 | 2024-02-27 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| JP7462762B2 (ja) | 2020-01-20 | 2024-04-05 | ウーシー バイオロジクス アイルランド リミテッド | アフィニティークロマトグラフィー用の新規な洗浄緩衝液 |
| JP2023511871A (ja) * | 2020-01-20 | 2023-03-23 | ウーシー バイオロジクス アイルランド リミテッド | アフィニティークロマトグラフィー用の新規な洗浄緩衝液 |
| JP2023542389A (ja) * | 2020-09-23 | 2023-10-06 | アブレヴィア バイオテック ゲーエムベーハー | 自己抗体で媒介される状態の予防又は治療のための化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US9493543B2 (en) | 2016-11-15 |
| JP2017190342A (ja) | 2017-10-19 |
| US20170015729A1 (en) | 2017-01-19 |
| EP2977055A1 (en) | 2016-01-27 |
| CN105153313A (zh) | 2015-12-16 |
| US20130040889A1 (en) | 2013-02-14 |
| CN102770450B (zh) | 2015-12-02 |
| WO2011101284A1 (en) | 2011-08-25 |
| JP2016084365A (ja) | 2016-05-19 |
| JP6185097B2 (ja) | 2017-08-23 |
| EP2536754A1 (en) | 2012-12-26 |
| CN102770450A (zh) | 2012-11-07 |
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