JP2013513388A5 - - Google Patents
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- JP2013513388A5 JP2013513388A5 JP2012543304A JP2012543304A JP2013513388A5 JP 2013513388 A5 JP2013513388 A5 JP 2013513388A5 JP 2012543304 A JP2012543304 A JP 2012543304A JP 2012543304 A JP2012543304 A JP 2012543304A JP 2013513388 A5 JP2013513388 A5 JP 2013513388A5
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- mouse
- heavy chain
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- human
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28525009P | 2009-12-10 | 2009-12-10 | |
| US61/285,250 | 2009-12-10 | ||
| PCT/US2010/059845 WO2011072204A1 (en) | 2009-12-10 | 2010-12-10 | Mice that make heavy chain antibodies |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015008099A Division JP6271450B2 (ja) | 2009-12-10 | 2015-01-19 | 重鎖抗体を作製するマウス |
| JP2015094069A Division JP6293702B2 (ja) | 2009-12-10 | 2015-05-01 | 重鎖抗体を作製するマウス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013513388A JP2013513388A (ja) | 2013-04-22 |
| JP2013513388A5 true JP2013513388A5 (https=) | 2015-03-12 |
| JP5909449B2 JP5909449B2 (ja) | 2016-04-26 |
Family
ID=43534479
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543304A Active JP5909449B2 (ja) | 2009-12-10 | 2010-12-10 | 重鎖抗体を作製するマウス |
| JP2015008099A Active JP6271450B2 (ja) | 2009-12-10 | 2015-01-19 | 重鎖抗体を作製するマウス |
| JP2015094069A Active JP6293702B2 (ja) | 2009-12-10 | 2015-05-01 | 重鎖抗体を作製するマウス |
| JP2017106527A Active JP6615830B2 (ja) | 2009-12-10 | 2017-05-30 | 重鎖抗体を作製するマウス |
| JP2019088172A Withdrawn JP2019141095A (ja) | 2009-12-10 | 2019-05-08 | 重鎖抗体を作製するマウス |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015008099A Active JP6271450B2 (ja) | 2009-12-10 | 2015-01-19 | 重鎖抗体を作製するマウス |
| JP2015094069A Active JP6293702B2 (ja) | 2009-12-10 | 2015-05-01 | 重鎖抗体を作製するマウス |
| JP2017106527A Active JP6615830B2 (ja) | 2009-12-10 | 2017-05-30 | 重鎖抗体を作製するマウス |
| JP2019088172A Withdrawn JP2019141095A (ja) | 2009-12-10 | 2019-05-08 | 重鎖抗体を作製するマウス |
Country Status (24)
| Country | Link |
|---|---|
| US (9) | US8754287B2 (https=) |
| EP (3) | EP2509409B1 (https=) |
| JP (5) | JP5909449B2 (https=) |
| KR (2) | KR101553244B1 (https=) |
| CN (3) | CN102711449B (https=) |
| AU (1) | AU2010328046C1 (https=) |
| CA (1) | CA2782936C (https=) |
| CY (2) | CY1118163T1 (https=) |
| DK (2) | DK2954779T3 (https=) |
| ES (2) | ES2724975T3 (https=) |
| HR (1) | HRP20190820T1 (https=) |
| HU (2) | HUE043556T2 (https=) |
| IL (4) | IL220150A0 (https=) |
| LT (2) | LT2954779T (https=) |
| MY (2) | MY173363A (https=) |
| PL (2) | PL2954779T3 (https=) |
| PT (2) | PT2954779T (https=) |
| RS (1) | RS58709B1 (https=) |
| RU (1) | RU2603102C2 (https=) |
| SG (2) | SG10201408181PA (https=) |
| SI (2) | SI2954779T1 (https=) |
| SM (1) | SMT201900251T1 (https=) |
| TR (1) | TR201906488T4 (https=) |
| WO (1) | WO2011072204A1 (https=) |
Families Citing this family (161)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101151957B1 (ko) | 2004-07-22 | 2012-06-01 | 로저 킹돈 크레이그 | 결합 분자 |
| AU2009298458B2 (en) | 2008-09-30 | 2015-10-08 | Ablexis, Llc | Non-human mammals for the production of chimeric antibodies |
| GB0905023D0 (en) | 2009-03-24 | 2009-05-06 | Univ Erasmus Medical Ct | Binding molecules |
| DK3622815T3 (da) | 2009-07-08 | 2023-06-26 | Kymab Ltd | Gnavermodeller og terapeutiske molekyler |
| US9445581B2 (en) | 2012-03-28 | 2016-09-20 | Kymab Limited | Animal models and therapeutic molecules |
| ES2724975T3 (es) * | 2009-12-10 | 2019-09-18 | Regeneron Pharma | Ratones que producen anticuerpos de cadena pesada |
| US20130045492A1 (en) | 2010-02-08 | 2013-02-21 | Regeneron Pharmaceuticals, Inc. | Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain |
| US9796788B2 (en) | 2010-02-08 | 2017-10-24 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
| SMT202600080T1 (it) | 2010-02-08 | 2026-03-09 | Regeneron Pharma | Topo con catena leggera comune |
| ES2984483T3 (es) | 2010-03-31 | 2024-10-29 | Ablexis Llc | Ingeniería genética de ratones para la producción de anticuerpos quiméricos |
| CN103025884B (zh) | 2010-07-26 | 2015-11-25 | 特里安尼公司 | 转基因动物和使用方法 |
| US10662256B2 (en) | 2010-07-26 | 2020-05-26 | Trianni, Inc. | Transgenic mammals and methods of use thereof |
| US10793829B2 (en) | 2010-07-26 | 2020-10-06 | Trianni, Inc. | Transgenic mammals and methods of use thereof |
| SMT201700023T1 (it) | 2010-08-02 | 2017-03-08 | Regeneron Pharma | Topi che producono proteine leganti vl |
| ME02106B (me) | 2011-02-25 | 2015-10-20 | Regeneron Pharma | Miševi sa adam6 |
| EP2683735A1 (en) * | 2011-03-10 | 2014-01-15 | HCO Antibody, Inc. | Bispecific three-chain antibody-like molecules |
| HUE047278T2 (hu) | 2011-08-05 | 2020-04-28 | Regeneron Pharma | Humanizált univerzális könnyûláncú egerek |
| GB2501753A (en) * | 2012-05-04 | 2013-11-06 | Kymab Ltd | Human antibodies |
| BR112014006394A2 (pt) | 2011-09-19 | 2017-03-28 | Kymab Ltd | manipulação de diversidade genética de imunoglobulina e terapêuticos multi-anticorpos |
| WO2013045916A1 (en) | 2011-09-26 | 2013-04-04 | Kymab Limited | Chimaeric surrogate light chains (slc) comprising human vpreb |
| SG11201401181YA (en) | 2011-10-17 | 2014-04-28 | Regeneron Pharma | Restricted immunoglobulin heavy chain mice |
| JP2015502356A (ja) * | 2011-11-30 | 2015-01-22 | ウェルスタット ダイアグノスティクス，エルエルシー | ５−ｆｕに関連するアッセイ、抗体、免疫原および組成物 |
| US9253965B2 (en) | 2012-03-28 | 2016-02-09 | Kymab Limited | Animal models and therapeutic molecules |
| SG10201605675WA (en) | 2011-12-20 | 2016-09-29 | Regeneron Pharma | Humanized light chain mice |
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