JP2013505260A5 - - Google Patents

Download PDF

Info

Publication number
JP2013505260A5
JP2013505260A5 JP2012529934A JP2012529934A JP2013505260A5 JP 2013505260 A5 JP2013505260 A5 JP 2013505260A5 JP 2012529934 A JP2012529934 A JP 2012529934A JP 2012529934 A JP2012529934 A JP 2012529934A JP 2013505260 A5 JP2013505260 A5 JP 2013505260A5
Authority
JP
Japan
Prior art keywords
effective amount
therapeutically effective
pharmaceutical composition
opioid
day
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012529934A
Other languages
English (en)
Japanese (ja)
Other versions
JP5797655B2 (ja
JP2013505260A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/049311 external-priority patent/WO2011035142A1/en
Publication of JP2013505260A publication Critical patent/JP2013505260A/ja
Publication of JP2013505260A5 publication Critical patent/JP2013505260A5/ja
Application granted granted Critical
Publication of JP5797655B2 publication Critical patent/JP5797655B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012529934A 2009-09-18 2010-09-17 消化管障害のためのオピオイド受容体アンタゴニストの使用 Expired - Fee Related JP5797655B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24361609P 2009-09-18 2009-09-18
US61/243,616 2009-09-18
PCT/US2010/049311 WO2011035142A1 (en) 2009-09-18 2010-09-17 Use of opioid receptor antagonist for gastrointestinal tract disorders

Publications (3)

Publication Number Publication Date
JP2013505260A JP2013505260A (ja) 2013-02-14
JP2013505260A5 true JP2013505260A5 (enExample) 2013-11-07
JP5797655B2 JP5797655B2 (ja) 2015-10-21

Family

ID=43216894

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012529934A Expired - Fee Related JP5797655B2 (ja) 2009-09-18 2010-09-17 消化管障害のためのオピオイド受容体アンタゴニストの使用

Country Status (19)

Country Link
US (1) US20110071163A1 (enExample)
EP (1) EP2477627B1 (enExample)
JP (1) JP5797655B2 (enExample)
KR (1) KR20120092592A (enExample)
CN (2) CN102695508A (enExample)
AU (1) AU2010295464B2 (enExample)
BR (1) BR112012006069A8 (enExample)
CA (1) CA2774021A1 (enExample)
CL (1) CL2012000676A1 (enExample)
CO (1) CO6531453A2 (enExample)
HK (1) HK1210959A1 (enExample)
IL (1) IL218679A0 (enExample)
MX (1) MX342548B (enExample)
NZ (1) NZ598783A (enExample)
PE (1) PE20120991A1 (enExample)
RU (1) RU2561873C2 (enExample)
TW (1) TW201118084A (enExample)
WO (1) WO2011035142A1 (enExample)
ZA (1) ZA201201954B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE027856T2 (en) * 2012-12-28 2016-11-28 Inst Medycyny Doswiadczalnej I Klinicznej Im Miroslawa Mossakowskiego Polskiej Akademii Nauk Peptidomimetics and their use
TW201808937A (zh) 2016-05-20 2018-03-16 艾斯提夫博士實驗股份有限公司 針對疼痛具有多模態活性的四氫哌喃和噻喃衍生物
CN106117190B (zh) * 2016-06-21 2019-03-29 山东川成医药股份有限公司 一种倍福普兰的合成方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191771A (en) * 1974-09-06 1980-03-04 Eli Lilly And Company Analgesic method using 1,3,4-trisubstituted-4-arylpiperidines
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
US4992450A (en) * 1987-04-16 1991-02-12 Eli Lilly And Company Piperidine opioid antagonists
US5319087A (en) * 1987-04-16 1994-06-07 Eli Lilly And Company Piperidine opioid antagonists
US4891379A (en) * 1987-04-16 1990-01-02 Kabushiki Kaisha Kobe Seikosho Piperidine opioid antagonists
US5064834A (en) * 1987-04-16 1991-11-12 Eli Lilly And Company Piperidine opioid antagonists
US5159081A (en) * 1991-03-29 1992-10-27 Eli Lilly And Company Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
US5270328A (en) * 1991-03-29 1993-12-14 Eli Lilly And Company Peripherally selective piperidine opioid antagonists
US5250542A (en) * 1991-03-29 1993-10-05 Eli Lilly And Company Peripherally selective piperidine carboxylate opioid antagonists
US5698155A (en) 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
JP3867171B2 (ja) 1994-04-22 2007-01-10 アステラス製薬株式会社 結腸特異的薬物放出システム
US5378448A (en) * 1994-06-07 1995-01-03 Lin; Hsing K. Process for removing selenium from sulfur
TW490465B (en) * 1994-11-24 2002-06-11 Janssen Pharmaceutica Nv Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof
ES2171839T3 (es) * 1996-09-05 2002-09-16 Lilly Co Eli Analogos de carbazol como agonistas adrenergicos selectivos de beta3.
US6559158B1 (en) * 1997-11-03 2003-05-06 Ur Labs, Inc. Use of methylnaltrexone and related compounds to treat chronic opioid use side affects
US6022884A (en) * 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
MXPA01003197A (es) 1998-09-28 2004-04-21 Warner Lambert Co Suministro enterico y colonico utilizando capsulas de chpm.
US6436959B1 (en) * 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides
US6194382B1 (en) * 1999-03-03 2001-02-27 Albert Einstein College Of Medicine Of Yeshiva University Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists
PT1220849E (pt) * 1999-10-15 2004-10-29 Sucampo Ag Composicao de compostos biciclicos e metodo para a sua estabilizacao
EP1225897B1 (en) * 1999-11-01 2004-09-08 RHODES, John Composition for treatment of constipation and irritable bowel syndrome
US6469030B2 (en) * 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
US6414016B1 (en) * 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
JP4340437B2 (ja) * 2000-10-31 2009-10-07 レンセラール ポリテクニック インスティチュート ８−カルボキサミド−２，６−メタノ−３−ベンズアゾシン
MXPA04002006A (es) * 2001-08-31 2004-06-07 Sucampo Ag Analogos de prostagladina como abridor del canal de cloruro.
PT2939696E (pt) * 2001-10-18 2016-06-17 Nektar Therapeutics Conjugados poliméricos de antagonistas de opióides
AR037524A1 (es) * 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
UA80437C2 (en) * 2002-09-19 2007-09-25 Lilly Co Eli Diaryl ethers as opioid receptor antagonist
ES2591252T3 (es) * 2002-12-27 2016-11-25 Sucampo Ag Derivados de prostaglandinas para tratar el síndrome de colon irritable y/o la dispepsia funcional
MXPA05009367A (es) * 2003-03-07 2005-11-04 Lilly Co Eli Antagonistas del receptor opioide.
BRPI0417156A (pt) * 2003-12-12 2007-03-06 Lilly Co Eli composto, composição farmacêutica, e, métodos para bloquear receptor mu, capa, delta ou combinação (heterodìmero) dos mesmos em mamìferos, para tratar e/ou prevenir doenças relacionadas com obesidade e obesidade, para suprimir apetite em um paciente, para efetuar perda de peso em um paciente obeso
WO2005066164A1 (en) * 2003-12-22 2005-07-21 Eli Lilly And Company Opioid receptor antagonists
US7381750B2 (en) * 2004-03-12 2008-06-03 Eli Lilly And Company Amino-phenoxymethyl-benzamide opioid receptor antagonists
ES2308471T3 (es) * 2004-03-12 2008-12-01 Eli Lilly And Company Antagonistas de receptores de opioides.
US8524731B2 (en) * 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
WO2006126529A1 (ja) * 2005-05-25 2006-11-30 Shionogi & Co., Ltd. ６，７－不飽和－７－カルバモイル置換モルヒナン誘導体
JP4783794B2 (ja) * 2006-01-24 2011-09-28 株式会社アールテック・ウエノ 軟ゼラチンカプセル製剤
MY145633A (en) * 2006-03-01 2012-03-15 Theravance Inc 8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists
TWI409067B (zh) * 2007-02-28 2013-09-21 Theravance Inc ８-氮雜雙環〔３．２．１〕辛烷化合物之結晶型
WO2009051824A2 (en) * 2007-10-18 2009-04-23 Aiko Biotechnology Combination analgesic employing opioid and neutral antagonist
JP5403762B2 (ja) * 2007-12-11 2014-01-29 セラヴァンス， インコーポレーテッド μオピオイド受容体アンタゴニストとしての３−カルボキシプロピル−アミノテトラリン誘導体
TWI449685B (zh) * 2008-12-10 2014-08-21 Theravance Inc ３－羧基丙基－胺基四氫化萘化合物之結晶型
SMT201900357T1 (it) * 2009-12-04 2019-07-11 Alkermes Pharma Ireland Ltd Derivati di morfinano per trattamento di abuso di sostanze stupefacenti

Similar Documents

Publication Publication Date Title
RU2013136350A (ru) Фармацевтическая композиция, содержащая опиоидный агонист и секвестрированный антагонист
JP6279547B2 (ja) オピオイド誘発性有害薬力学的応答を治療するためのシステムおよび方法
JP2011137020A5 (enExample)
JP2010535252A5 (enExample)
JP2013527167A5 (enExample)
WO2007005716A2 (en) Methods of treatment and compositions for use thereof
JP2011519930A5 (enExample)
JP2010521417A5 (enExample)
JP2014505107A5 (enExample)
JP2015514743A5 (enExample)
JP2011515415A5 (enExample)
RU2683317C2 (ru) Конъюгаты оксикодона с бензойной кислотой, производными бензойной кислоты и гетероарилкарбоновой кислотой
JP2016507500A5 (enExample)
JP2013505260A5 (enExample)
EA200870182A1 (ru) Применение комбинации морфина и по меньшей мере одного антагониста опиатов для лечения зависимости от опиатов для предотвращения непероральной опиатомании у наркоманов
WO2007145863A3 (en) Sustained release formulation of naltrexone
US20180338968A1 (en) Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof
JP2010540648A5 (enExample)
JP2014515405A (ja) オピオイド受容体アゴニストの逐次投与のための組成物
JP7244992B2 (ja) オピオイドとｎ－アシルエタノールアミンの組み合わせ
RU2012115450A (ru) Применение антагонистов опиоидных рецепторов при заболеваниях желудочно-кишечного тракта
JP2017526719A5 (enExample)
RU2003135201A (ru) Применение антагониста опиоидов налтрексона для предупреждения и контроля побочных воздействий, вызванных опиоидами
JP2015515982A5 (enExample)
WO2018204163A1 (en) An opioid for use to reduce and/or treat drug addiction