CN102695508A - 阿片样受体拮抗剂用于胃肠道疾病的用途 - Google Patents

阿片样受体拮抗剂用于胃肠道疾病的用途 Download PDF

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Publication number
CN102695508A
CN102695508A CN2010800522092A CN201080052209A CN102695508A CN 102695508 A CN102695508 A CN 102695508A CN 2010800522092 A CN2010800522092 A CN 2010800522092A CN 201080052209 A CN201080052209 A CN 201080052209A CN 102695508 A CN102695508 A CN 102695508A
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CN
China
Prior art keywords
compound
opioid
effective amount
therapeutically effective
formula
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Pending
Application number
CN2010800522092A
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English (en)
Chinese (zh)
Inventor
R.M.伍德沃德
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Adolor Corp
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Adolor Corp
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43216894&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN102695508(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adolor Corp filed Critical Adolor Corp
Priority to CN201510256187.6A priority Critical patent/CN104958298A/zh
Publication of CN102695508A publication Critical patent/CN102695508A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN2010800522092A 2009-09-18 2010-09-17 阿片样受体拮抗剂用于胃肠道疾病的用途 Pending CN102695508A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510256187.6A CN104958298A (zh) 2009-09-18 2010-09-17 阿片样受体拮抗剂用于胃肠道疾病的用途

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24361609P 2009-09-18 2009-09-18
US61/243,616 2009-09-18
PCT/US2010/049311 WO2011035142A1 (en) 2009-09-18 2010-09-17 Use of opioid receptor antagonist for gastrointestinal tract disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201510256187.6A Division CN104958298A (zh) 2009-09-18 2010-09-17 阿片样受体拮抗剂用于胃肠道疾病的用途

Publications (1)

Publication Number Publication Date
CN102695508A true CN102695508A (zh) 2012-09-26

Family

ID=43216894

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2010800522092A Pending CN102695508A (zh) 2009-09-18 2010-09-17 阿片样受体拮抗剂用于胃肠道疾病的用途
CN201510256187.6A Pending CN104958298A (zh) 2009-09-18 2010-09-17 阿片样受体拮抗剂用于胃肠道疾病的用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201510256187.6A Pending CN104958298A (zh) 2009-09-18 2010-09-17 阿片样受体拮抗剂用于胃肠道疾病的用途

Country Status (19)

Country Link
US (1) US20110071163A1 (enExample)
EP (1) EP2477627B1 (enExample)
JP (1) JP5797655B2 (enExample)
KR (1) KR20120092592A (enExample)
CN (2) CN102695508A (enExample)
AU (1) AU2010295464B2 (enExample)
BR (1) BR112012006069A8 (enExample)
CA (1) CA2774021A1 (enExample)
CL (1) CL2012000676A1 (enExample)
CO (1) CO6531453A2 (enExample)
HK (1) HK1210959A1 (enExample)
IL (1) IL218679A0 (enExample)
MX (1) MX342548B (enExample)
NZ (1) NZ598783A (enExample)
PE (1) PE20120991A1 (enExample)
RU (1) RU2561873C2 (enExample)
TW (1) TW201118084A (enExample)
WO (1) WO2011035142A1 (enExample)
ZA (1) ZA201201954B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106117190A (zh) * 2016-06-21 2016-11-16 山东川成医药股份有限公司 一种倍福普兰的合成方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE027856T2 (en) * 2012-12-28 2016-11-28 Inst Medycyny Doswiadczalnej I Klinicznej Im Miroslawa Mossakowskiego Polskiej Akademii Nauk Peptidomimetics and their use
TW201808937A (zh) 2016-05-20 2018-03-16 艾斯提夫博士實驗股份有限公司 針對疼痛具有多模態活性的四氫哌喃和噻喃衍生物

Citations (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106117190A (zh) * 2016-06-21 2016-11-16 山东川成医药股份有限公司 一种倍福普兰的合成方法
CN106117190B (zh) * 2016-06-21 2019-03-29 山东川成医药股份有限公司 一种倍福普兰的合成方法

Also Published As

Publication number Publication date
CN104958298A (zh) 2015-10-07
BR112012006069A8 (pt) 2017-10-10
NZ598783A (en) 2013-07-26
AU2010295464B2 (en) 2015-11-26
IL218679A0 (en) 2012-05-31
KR20120092592A (ko) 2012-08-21
PE20120991A1 (es) 2012-08-01
ZA201201954B (en) 2012-11-28
WO2011035142A1 (en) 2011-03-24
HK1210959A1 (en) 2016-05-13
US20110071163A1 (en) 2011-03-24
JP5797655B2 (ja) 2015-10-21
BR112012006069A2 (pt) 2016-03-29
MX2012003310A (es) 2012-07-17
RU2561873C2 (ru) 2015-09-10
MX342548B (es) 2016-10-04
AU2010295464A1 (en) 2012-04-12
EP2477627A1 (en) 2012-07-25
EP2477627B1 (en) 2018-08-15
JP2013505260A (ja) 2013-02-14
TW201118084A (en) 2011-06-01
RU2012115450A (ru) 2013-10-27
CO6531453A2 (es) 2012-09-28
CA2774021A1 (en) 2011-03-24
CL2012000676A1 (es) 2012-10-19

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Application publication date: 20120926