PE20120991A1 - Antagonista del receptor opiaceo para los trastornos del tracto gastrointestinal - Google Patents

Antagonista del receptor opiaceo para los trastornos del tracto gastrointestinal

Info

Publication number
PE20120991A1
PE20120991A1 PE2012000347A PE2012000347A PE20120991A1 PE 20120991 A1 PE20120991 A1 PE 20120991A1 PE 2012000347 A PE2012000347 A PE 2012000347A PE 2012000347 A PE2012000347 A PE 2012000347A PE 20120991 A1 PE20120991 A1 PE 20120991A1
Authority
PE
Peru
Prior art keywords
opious
disorders
gastrointestinal tract
receptor antagonist
opiaceous
Prior art date
Application number
PE2012000347A
Other languages
English (en)
Inventor
Richard M Woodward
Original Assignee
Adolor Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43216894&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20120991(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adolor Corp filed Critical Adolor Corp
Publication of PE20120991A1 publication Critical patent/PE20120991A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Abstract

REFERIDA AL COMPUESTO 5-(2-METOXI-4-{[2-(TETRAHIDRO-PIRAN-4-IL)-ETILAMINO]-METIL}-FENOXI)-PIRAZIN-2-CARBOXAMIDA (COMPUESTO I) EL CUAL ES UN ANTAGONISTA DEL RECEPTOR OPIACEO Y ES UTIL EN EL TRATAMIENTO DEL ESTRENIMIENTO INDUCIDO POR OPIACEOS O DISFUNCION DEL INTESTINO INDUCIDA POR OPIACEOS SIN REDUCIR LA ANALGESIA DEL OPIACEO
PE2012000347A 2009-09-18 2010-09-17 Antagonista del receptor opiaceo para los trastornos del tracto gastrointestinal PE20120991A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24361609P 2009-09-18 2009-09-18

Publications (1)

Publication Number Publication Date
PE20120991A1 true PE20120991A1 (es) 2012-08-01

Family

ID=43216894

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2012000347A PE20120991A1 (es) 2009-09-18 2010-09-17 Antagonista del receptor opiaceo para los trastornos del tracto gastrointestinal

Country Status (19)

Country Link
US (1) US20110071163A1 (es)
EP (1) EP2477627B1 (es)
JP (1) JP5797655B2 (es)
KR (1) KR20120092592A (es)
CN (2) CN102695508A (es)
AU (1) AU2010295464B2 (es)
BR (1) BR112012006069A8 (es)
CA (1) CA2774021A1 (es)
CL (1) CL2012000676A1 (es)
CO (1) CO6531453A2 (es)
HK (1) HK1210959A1 (es)
IL (1) IL218679A0 (es)
MX (1) MX342548B (es)
NZ (1) NZ598783A (es)
PE (1) PE20120991A1 (es)
RU (1) RU2561873C2 (es)
TW (1) TW201118084A (es)
WO (1) WO2011035142A1 (es)
ZA (1) ZA201201954B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2548782T3 (es) 2012-12-28 2015-10-20 Instytut Medycyny Doswiadczalnej I Klinicznej Im Miroslawa Mossakowskiego Polskiej Akademii Nauk Peptidomiméticos y su aplicación
ES2823588T3 (es) 2016-05-20 2021-05-07 Esteve Pharmaceuticals Sa Derivados de tetrahidropirano que tienen actividad multimodal contra el dolor
CN106117190B (zh) * 2016-06-21 2019-03-29 山东川成医药股份有限公司 一种倍福普兰的合成方法

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US4992450A (en) * 1987-04-16 1991-02-12 Eli Lilly And Company Piperidine opioid antagonists
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WO2000018377A1 (en) 1998-09-28 2000-04-06 Warner-Lambert Company Enteric and colonic delivery using hpmc capsules
US6436959B1 (en) * 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides
US6194382B1 (en) * 1999-03-03 2001-02-27 Albert Einstein College Of Medicine Of Yeshiva University Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists
DK1220849T3 (da) * 1999-10-15 2004-09-27 Sucampo Ag Sammensætninger med bicykliske forbindelser og fremgangsmåde til stabilisering heraf
CZ299726B6 (cs) * 1999-11-01 2008-11-05 Lécivo pro lécení zácpy a syndromu dráždivého tracníku
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ATE391712T1 (de) * 2000-10-31 2008-04-15 Rensselaer Polytech Inst 4-arylpiperidine als opioidrezeptorbindende agenzien
WO2003030912A1 (en) * 2001-08-31 2003-04-17 Sucampo Ag Prostaglandin analogs as chloride channel opener
WO2003032990A2 (en) * 2001-10-18 2003-04-24 Nektar Therapeutics Al, Corporation Polymer conjugates of opioid antagonists
TWI331920B (en) * 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
PL212616B1 (pl) * 2002-09-19 2012-10-31 Lilly Co Eli Eter diarylowy i kompozycja farmaceutyczna zawierajaca ten eter
TWI336254B (en) * 2002-12-27 2011-01-21 Sucampo Ag Pharmaceutical composition for treating abdominal discomfort
AU2004220113A1 (en) * 2003-03-07 2004-09-23 Eli Lilly And Company Opioid receptor antagonists
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EP1699783B1 (en) * 2003-12-22 2012-07-25 Eli Lilly And Company Opioid receptor antagonists
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Also Published As

Publication number Publication date
IL218679A0 (en) 2012-05-31
AU2010295464B2 (en) 2015-11-26
JP2013505260A (ja) 2013-02-14
CN102695508A (zh) 2012-09-26
ZA201201954B (en) 2012-11-28
BR112012006069A8 (pt) 2017-10-10
MX2012003310A (es) 2012-07-17
BR112012006069A2 (pt) 2016-03-29
TW201118084A (en) 2011-06-01
EP2477627A1 (en) 2012-07-25
JP5797655B2 (ja) 2015-10-21
AU2010295464A1 (en) 2012-04-12
RU2012115450A (ru) 2013-10-27
US20110071163A1 (en) 2011-03-24
RU2561873C2 (ru) 2015-09-10
EP2477627B1 (en) 2018-08-15
CL2012000676A1 (es) 2012-10-19
CA2774021A1 (en) 2011-03-24
CN104958298A (zh) 2015-10-07
MX342548B (es) 2016-10-04
NZ598783A (en) 2013-07-26
KR20120092592A (ko) 2012-08-21
WO2011035142A1 (en) 2011-03-24
HK1210959A1 (en) 2016-05-13
CO6531453A2 (es) 2012-09-28

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