JP2013502931A5 - - Google Patents
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- JP2013502931A5 JP2013502931A5 JP2012527011A JP2012527011A JP2013502931A5 JP 2013502931 A5 JP2013502931 A5 JP 2013502931A5 JP 2012527011 A JP2012527011 A JP 2012527011A JP 2012527011 A JP2012527011 A JP 2012527011A JP 2013502931 A5 JP2013502931 A5 JP 2013502931A5
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- mirna
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- lung cancer
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- 108091070501 miRNA Proteins 0.000 claims description 45
- 238000000034 method Methods 0.000 claims description 43
- 239000002679 microRNA Substances 0.000 claims description 42
- -1 miR-195 Proteins 0.000 claims description 25
- 208000020816 lung neoplasm Diseases 0.000 claims description 16
- 208000019693 Lung disease Diseases 0.000 claims description 14
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims description 13
- 201000005202 lung cancer Diseases 0.000 claims description 13
- 210000002966 serum Anatomy 0.000 claims description 10
- 108091079658 miR-142-1 stem-loop Proteins 0.000 claims description 8
- 108091071830 miR-142-2 stem-loop Proteins 0.000 claims description 8
- 108091028066 Mir-126 Proteins 0.000 claims description 7
- 108091031326 miR-15b stem-loop Proteins 0.000 claims description 6
- 108091044721 miR-422a stem-loop Proteins 0.000 claims description 6
- 108091028080 MiR-132 Proteins 0.000 claims description 5
- 108091073628 miR-181d stem-loop Proteins 0.000 claims description 5
- 108091048308 miR-210 stem-loop Proteins 0.000 claims description 5
- 108091070404 miR-27b stem-loop Proteins 0.000 claims description 5
- 108091046551 miR-324 stem-loop Proteins 0.000 claims description 5
- 108091046841 MiR-150 Proteins 0.000 claims description 4
- 108091033773 MiR-155 Proteins 0.000 claims description 4
- 108091028049 Mir-221 microRNA Proteins 0.000 claims description 4
- 108091060302 Mir-320 Proteins 0.000 claims description 4
- 206010028980 Neoplasm Diseases 0.000 claims description 4
- 238000010240 RT-PCR analysis Methods 0.000 claims description 4
- 206010041067 Small cell lung cancer Diseases 0.000 claims description 4
- 230000003321 amplification Effects 0.000 claims description 4
- 201000011510 cancer Diseases 0.000 claims description 4
- 230000003902 lesion Effects 0.000 claims description 4
- 108091007423 let-7b Proteins 0.000 claims description 4
- 108091033753 let-7d stem-loop Proteins 0.000 claims description 4
- 108091007427 let-7g Proteins 0.000 claims description 4
- 208000037841 lung tumor Diseases 0.000 claims description 4
- 108091028466 miR-130b stem-loop Proteins 0.000 claims description 4
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- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims description 4
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 4
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- 108091063986 let-7f stem-loop Proteins 0.000 claims description 2
- 108091042844 let-7i stem-loop Proteins 0.000 claims description 2
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- 108091064157 miR-106a stem-loop Proteins 0.000 claims description 2
- 108091035155 miR-10a stem-loop Proteins 0.000 claims description 2
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- 108091061917 miR-221 stem-loop Proteins 0.000 claims description 2
- 108091063489 miR-221-1 stem-loop Proteins 0.000 claims description 2
- 108091055391 miR-221-2 stem-loop Proteins 0.000 claims description 2
- 108091031076 miR-221-3 stem-loop Proteins 0.000 claims description 2
- 108091080321 miR-222 stem-loop Proteins 0.000 claims description 2
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- 108091061970 miR-26a stem-loop Proteins 0.000 claims description 2
- 108091083275 miR-26b stem-loop Proteins 0.000 claims description 2
- 108091088477 miR-29a stem-loop Proteins 0.000 claims description 2
- 108091029716 miR-29a-1 stem-loop Proteins 0.000 claims description 2
- 108091092089 miR-29a-2 stem-loop Proteins 0.000 claims description 2
- 108091066559 miR-29a-3 stem-loop Proteins 0.000 claims description 2
- 108091063344 miR-30b stem-loop Proteins 0.000 claims description 2
- 108091055059 miR-30c stem-loop Proteins 0.000 claims description 2
- 108091057431 miR-30d stem-loop Proteins 0.000 claims description 2
- 108091023108 miR-30e stem-loop Proteins 0.000 claims description 2
- 108091027549 miR-30e-1 stem-loop Proteins 0.000 claims description 2
- 108091029213 miR-30e-2 stem-loop Proteins 0.000 claims description 2
- 108091085488 miR-30e-3 stem-loop Proteins 0.000 claims description 2
- 108091042879 miR-326 stem-loop Proteins 0.000 claims description 2
- 108091031484 miR-335 stem-loop Proteins 0.000 claims description 2
- 108091065159 miR-339 stem-loop Proteins 0.000 claims description 2
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- 108091029119 miR-34a stem-loop Proteins 0.000 claims description 2
- 108091030670 miR-365 stem-loop Proteins 0.000 claims description 2
- 108091036688 miR-365-3 stem-loop Proteins 0.000 claims description 2
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- 108091035982 miR-485 stem-loop Proteins 0.000 claims description 2
- 108091041309 miR-505 stem-loop Proteins 0.000 claims description 2
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- 108091023818 miR-7 stem-loop Proteins 0.000 claims description 2
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- 108091053257 miR-99b stem-loop Proteins 0.000 claims description 2
- 238000012216 screening Methods 0.000 claims description 2
- 108091063348 miR-193 stem-loop Proteins 0.000 claims 1
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- 108091026807 MiR-214 Proteins 0.000 description 3
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- 239000000090 biomarker Substances 0.000 description 1
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- 108091047758 miR-185 stem-loop Proteins 0.000 description 1
- 108091063796 miR-206 stem-loop Proteins 0.000 description 1
- 108091048549 miR-29b stem-loop Proteins 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23797209P | 2009-08-28 | 2009-08-28 | |
| US61/237,972 | 2009-08-28 | ||
| PCT/US2010/046916 WO2011025919A1 (en) | 2009-08-28 | 2010-08-27 | Mirna biomarkers of lung disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013502931A JP2013502931A (ja) | 2013-01-31 |
| JP2013502931A5 true JP2013502931A5 (cg-RX-API-DMAC7.html) | 2013-10-10 |
| JP5995721B2 JP5995721B2 (ja) | 2016-09-21 |
Family
ID=43625469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012527011A Expired - Fee Related JP5995721B2 (ja) | 2009-08-28 | 2010-08-27 | 肺疾患のｍｉＲＮＡバイオマーカー |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8735074B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2775300A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5995721B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102725632A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011025919A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100035244A1 (en) | 2005-04-14 | 2010-02-11 | The Trustees Of Boston University | Diagnostic for lung disorders using class prediction |
| AU2007223788B2 (en) | 2006-03-09 | 2012-11-29 | The Trustees Of Boston University | Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells |
| WO2009039457A1 (en) | 2007-09-19 | 2009-03-26 | The Trustees Of Boston University | Identification of novel pathways for drug development for lung disease |
| US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US20100240049A1 (en) | 2009-01-16 | 2010-09-23 | Cepheid | Methods of Detecting Cervical Cancer |
| CN102459636B (zh) | 2009-05-07 | 2016-08-17 | 威拉赛特公司 | 用于诊断甲状腺病症的方法和组合物 |
| EP2505663A1 (en) | 2011-03-30 | 2012-10-03 | IFOM Fondazione Istituto Firc di Oncologia Molecolare | A method to identify asymptomatic high-risk individuals with early stage lung cancer by means of detecting miRNAs in biologic fluids |
| WO2012103355A2 (en) | 2011-01-26 | 2012-08-02 | Cepheid | Methods of detecting lung cancer |
| JP6021893B2 (ja) | 2011-04-18 | 2016-11-09 | ディアミール, エルエルシーDiamir, Llc | 軽度認知機能障害（ＭＣＩ）およびアルツハイマー病（ＡＤ）の早期検出ならびにモニタリングのために体液からのｍｉＲＮＡを使用する方法 |
| EE201100037A (et) | 2011-05-16 | 2012-12-17 | Tartu Ülikool | MikroRNAde kasutamine biomarkeritena ja sihtmrkidena raku proliferatiivsete omaduste m?jutamiseks ja meetod ning komplekt nende ekspressioonitaseme tuvastamiseks |
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| CN102851282B (zh) * | 2011-06-30 | 2014-10-08 | 上海市肿瘤研究所 | 用于区分原发性肺癌与癌旁组织的microRNA标志物 |
| CA2844197A1 (en) | 2011-08-03 | 2013-02-07 | The Charlotte-Mecklenburg Hospital Authority D/B/A Carolina Healthcare System | Treatment of fibrosis using microrna-19b |
| US20130040303A1 (en) * | 2011-08-08 | 2013-02-14 | Eugenia Wang | Biomarker for Alzheimer's Disease and/or Mild Cognitive Impairment, and Use Thereof |
| EP2751292A4 (en) * | 2011-09-01 | 2015-05-20 | Allegro Diagnostics Corp | METHOD AND COMPOSITIONS FOR DETECTING CANCER BASED ON MIRNA EXPRESSION PROFILES |
| US9745578B2 (en) | 2011-11-30 | 2017-08-29 | Cedars-Sinai Medical Center | Targeting microRNA miR-409-3P to treat prostate cancer |
| CA2799163C (en) | 2011-12-18 | 2025-01-07 | 20/20 Genesystems, Inc. | METHODS AND ALGORITHMS TO AID IN CANCER DETECTION |
| EP2800820B1 (en) | 2011-12-19 | 2020-04-08 | Valley Health System | Methods and kits for detecting subjects having pancreatic cancer |
| CN102533983A (zh) * | 2011-12-19 | 2012-07-04 | 苏州福英基因科技有限公司 | 癌症病理演变前期microrna-330水平原位杂交检测试剂盒及检测方法和应用 |
| JP2015512249A (ja) | 2012-03-19 | 2015-04-27 | プレスティズィアＰｒｅｓｔｉｚｉａ | 循環から採取される身体試料中のウイルス、特に、ｈｉｖの親和性及び受容体使用の決定方法 |
| CN102743765A (zh) * | 2012-05-24 | 2012-10-24 | 上海大学 | 非小细胞肺癌中miR-10a基因的应用 |
| WO2014186036A1 (en) | 2013-03-14 | 2014-11-20 | Allegro Diagnostics Corp. | Methods for evaluating copd status |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| CN103602678B (zh) * | 2013-06-18 | 2016-02-10 | 潘世扬 | 非小细胞肺癌预后检测组合物及其应用 |
| CN103751801A (zh) * | 2013-09-10 | 2014-04-30 | 上海大学 | 非小细胞肺癌中miR-143基因的应用 |
| CN103555724B (zh) * | 2013-10-24 | 2015-08-05 | 浙江理工大学 | 2型糖尿病的血清miRNA生物标志物及其应用 |
| ES2813699T3 (es) | 2013-11-18 | 2021-03-24 | Diamir Llc | Métodos de uso de miARN de fluidos corporales para la detección y monitoreo de la enfermedad de Parkinson (PD) |
| CN103667459A (zh) * | 2013-11-26 | 2014-03-26 | 上海中医药大学附属岳阳中西医结合医院 | 微小核苷酸在高血压诊断和制备降血压药物中的应用 |
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| CN103937826B (zh) * | 2014-04-04 | 2016-04-06 | 东华大学 | 一种中枢神经系统中特异表达miR-505的载体的制备方法 |
| FR3019901B1 (fr) * | 2014-04-09 | 2020-10-30 | Bio Rad Innovations | Marqueur de controle pour la mise en oeuvre de procedes d'analyse sur spots |
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| WO2018009915A1 (en) | 2016-07-08 | 2018-01-11 | Trustees Of Boston University | Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions |
| WO2018170622A1 (zh) * | 2017-03-18 | 2018-09-27 | 深圳市博奥康生物科技有限公司 | 一种同步下调微小rna-152和微小rna-185表达的方法 |
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