JP2013500006A5 - - Google Patents
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- JP2013500006A5 JP2013500006A5 JP2012521593A JP2012521593A JP2013500006A5 JP 2013500006 A5 JP2013500006 A5 JP 2013500006A5 JP 2012521593 A JP2012521593 A JP 2012521593A JP 2012521593 A JP2012521593 A JP 2012521593A JP 2013500006 A5 JP2013500006 A5 JP 2013500006A5
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- 210000004027 cell Anatomy 0.000 claims 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 12
- 230000000694 effects Effects 0.000 claims 12
- 230000001419 dependent effect Effects 0.000 claims 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 9
- 210000005253 yeast cell Anatomy 0.000 claims 7
- 102100036669 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic Human genes 0.000 claims 5
- 150000001720 carbohydrates Chemical class 0.000 claims 5
- 150000007523 nucleic acids Chemical group 0.000 claims 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 4
- 230000015572 biosynthetic process Effects 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 230000035772 mutation Effects 0.000 claims 4
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 claims 4
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 238000003786 synthesis reaction Methods 0.000 claims 4
- 102000008146 Acetate-CoA ligase Human genes 0.000 claims 3
- 108010049926 Acetate-CoA ligase Proteins 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 108010041921 Glycerolphosphate Dehydrogenase Proteins 0.000 claims 3
- 108010081577 aldehyde dehydrogenase (NAD(P)+) Proteins 0.000 claims 3
- 238000002360 preparation method Methods 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 108010021809 Alcohol dehydrogenase Proteins 0.000 claims 2
- 102000007698 Alcohol dehydrogenase Human genes 0.000 claims 2
- 241000722885 Brettanomyces Species 0.000 claims 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims 2
- XYZZKVRWGOWVGO-UHFFFAOYSA-N Glycerol-phosphate Chemical compound OP(O)(O)=O.OCC(O)CO XYZZKVRWGOWVGO-UHFFFAOYSA-N 0.000 claims 2
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 claims 2
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 claims 2
- 241000235070 Saccharomyces Species 0.000 claims 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims 1
- 101710088194 Dehydrogenase Proteins 0.000 claims 1
- 229930091371 Fructose Natural products 0.000 claims 1
- 239000005715 Fructose Substances 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 101150004714 GPP1 gene Proteins 0.000 claims 1
- 101150059691 GPP2 gene Proteins 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 102100030395 Glycerol-3-phosphate dehydrogenase, mitochondrial Human genes 0.000 claims 1
- 229920002488 Hemicellulose Polymers 0.000 claims 1
- 101001072574 Homo sapiens Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic Proteins 0.000 claims 1
- 101001009678 Homo sapiens Glycerol-3-phosphate dehydrogenase, mitochondrial Proteins 0.000 claims 1
- 235000014663 Kluyveromyces fragilis Nutrition 0.000 claims 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 1
- 244000253911 Saccharomyces fragilis Species 0.000 claims 1
- 235000018368 Saccharomyces fragilis Nutrition 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 claims 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 238000000855 fermentation Methods 0.000 claims 1
- 230000004151 fermentation Effects 0.000 claims 1
- 229930182830 galactose Natural products 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 229940031154 kluyveromyces marxianus Drugs 0.000 claims 1
- 239000002029 lignocellulosic biomass Substances 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 230000009261 transgenic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09166360.9 | 2009-07-24 | ||
| EP09166360A EP2277989A1 (en) | 2009-07-24 | 2009-07-24 | Fermentative glycerol-free ethanol production |
| PCT/NL2010/050475 WO2011010923A1 (en) | 2009-07-24 | 2010-07-23 | Fermentative glycerol-free ethanol production |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013500006A JP2013500006A (ja) | 2013-01-07 |
| JP2013500006A5 true JP2013500006A5 (cg-RX-API-DMAC10.html) | 2013-08-22 |
| JP5836271B2 JP5836271B2 (ja) | 2015-12-24 |
Family
ID=41460190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012521593A Active JP5836271B2 (ja) | 2009-07-24 | 2010-07-23 | グリセロールを含まない発酵によるエタノール生成 |
Country Status (15)
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2277989A1 (en) * | 2009-07-24 | 2011-01-26 | Technische Universiteit Delft | Fermentative glycerol-free ethanol production |
| WO2011140386A2 (en) * | 2010-05-05 | 2011-11-10 | Mascoma Corporation | Detoxification of biomass derived acetate via metabolic conversion to ethanol, acetone, isopropanol, or ethyl acetate |
| WO2011149353A1 (en) * | 2010-05-27 | 2011-12-01 | C5 Yeast Company B.V. | Yeast strains engineered to produce ethanol from acetic acid and glycerol |
| BR112012031362A2 (pt) | 2010-06-03 | 2015-10-13 | Mascoma Corp | levedura expressando enzimas sacarolíticas para bioprocessamento consolidado usando amido e celulose |
| EP3483279A1 (en) | 2011-04-05 | 2019-05-15 | Lallemand Hungary Liquidity Management LLC | Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors |
| WO2013061941A1 (ja) | 2011-10-24 | 2013-05-02 | トヨタ自動車株式会社 | 組換え酵母を用いたエタノールの製造方法 |
| ES2628847T3 (es) | 2011-11-09 | 2017-08-04 | Amyris, Inc. | Producción de isoprenoides derivados de acetil-coenzima a |
| BR112014012963B8 (pt) * | 2011-11-30 | 2022-04-26 | Dsm Ip Assets Bv | Processo para a produção de etanol e célula de levedura |
| CA2857498A1 (en) * | 2011-11-30 | 2013-09-26 | Mascoma Corporation | Engineering an increase in ethanol production by altering cofactor specificity |
| WO2014033019A1 (en) * | 2012-08-28 | 2014-03-06 | Dsm Ip Assets B.V. | Yeast strains engineered to produce ethanol from acetate |
| IN2015DN01041A (cg-RX-API-DMAC10.html) * | 2012-08-28 | 2015-06-26 | Dsm Ip Assets Bv | |
| US9745560B2 (en) | 2012-08-29 | 2017-08-29 | Lallemand Hungary Liquidity Management Llc | Expression of enzymes in yeast for lignocellulose derived oligomer CBP |
| EP2917343A2 (en) | 2012-11-09 | 2015-09-16 | Lallemand Hungary Liquidity Management LLC | Method for acetate consumption during ethanolic fermentation of cellulosic feedstocks |
| CA2902149C (en) | 2013-02-22 | 2022-07-26 | Technische Universiteit Delft | Recombinant micro-organism for use in method with increased product yield |
| US20160002674A1 (en) * | 2013-02-27 | 2016-01-07 | Toyota Jidosha Kabushiki Kaisha | Method for producing ethanol using recombinant yeast |
| ES2735024T3 (es) | 2013-03-14 | 2019-12-13 | Du Pont | Glicerol-3-fosfato deshidrogenasa para la producción de butanol |
| US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
| EP2970864B1 (en) | 2013-03-15 | 2020-10-28 | Lallemand Hungary Liquidity Management LLC | Methods for regulating nitrogen metabolism during the production of ethanol from corn by metabolically engineered yeast strains |
| WO2014180820A2 (en) * | 2013-05-08 | 2014-11-13 | Dsm Ip Assets B.V. | Gpd- yeast strains with improved osmotolerance |
| WO2015023989A1 (en) | 2013-08-15 | 2015-02-19 | Lallemand Hungary Liquidity Management Llc | Methods for the improvement of product yield and production in a microorganism through glycerol recycling |
| AR097480A1 (es) * | 2013-08-29 | 2016-03-16 | Dsm Ip Assets Bv | Células de levadura convertidoras de glicerol y ácido acético con una conversión de ácido acético mejorada |
| EP3063263A1 (en) | 2013-10-28 | 2016-09-07 | Danisco US Inc. | Large scale genetically engineered active dry yeast |
| KR102255306B1 (ko) * | 2013-11-15 | 2021-05-25 | 삼성전자주식회사 | 아세트알데히드 데히드로게나제를 포함하는 락테이트 생산능을 갖는 유전적으로 조작된 효모 세포, 그를 제조하는 방법 및 그를 사용하여 락테이트를 생산하는 방법 |
| US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
| AU2015231037B2 (en) * | 2014-03-21 | 2022-03-24 | Microbiogen Pty. Ltd. | Processes for producing ethanol and yeast |
| CN106687576B (zh) | 2014-03-28 | 2021-10-29 | 丹尼斯科美国公司 | 用于提高乙醇生产的改变的宿主细胞途径 |
| KR20160012561A (ko) * | 2014-07-24 | 2016-02-03 | 삼성전자주식회사 | Erg5의 활성이 증가되도록 유전적으로 조작된, 내산성을 갖는 효모 세포 및 그를 이용하여 락테이트를 생산하는 방법 |
| WO2016153924A1 (en) * | 2015-03-20 | 2016-09-29 | Novozymes A/S | Processes for producing ethanol and ethanol producing yeast |
| ES2755680T3 (es) * | 2015-05-22 | 2020-04-23 | Dsm Ip Assets Bv | Célula de levadura que consume acetato |
| MY186400A (en) * | 2015-10-06 | 2021-07-22 | Dsm Ip Assets Bv | Eukaryotic cell with increased production of fermentation product |
| EP3448988A1 (en) * | 2016-04-28 | 2019-03-06 | Danisco US Inc. | Redox balancing in yeast |
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| JP6447583B2 (ja) * | 2016-06-24 | 2019-01-09 | トヨタ自動車株式会社 | 組換え酵母、及びそれを用いたエタノールの製造方法 |
| CN110177801B (zh) | 2016-11-09 | 2024-02-23 | 丹尼斯科美国公司 | 具有改善的醇生产的酵母 |
| CA3047268A1 (en) | 2016-12-16 | 2018-06-21 | Danisco Us Inc. | Bifunctional phosphoketolase-phosphotransacetylase fusion polypeptides |
| CN110088288B (zh) * | 2016-12-20 | 2023-08-29 | 帝斯曼知识产权资产管理有限公司 | 用于乙醇生产的改良酵母菌株 |
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| JP6879111B2 (ja) | 2017-08-02 | 2021-06-02 | トヨタ自動車株式会社 | 組換え酵母及びこれを用いたエタノールの製造方法 |
| UY37835A (es) | 2017-08-08 | 2019-03-29 | Danisco Us Inc | Producción incrementada de etanol por levaduras que albergan alelos del activador de transcripción constitutivo mal |
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| WO2019063507A1 (en) | 2017-09-26 | 2019-04-04 | Dsm Ip Assets B.V. | IMPROVED PROCESS FOR THE PRODUCTION OF ETHANOL |
| EP3688177A1 (en) | 2017-09-26 | 2020-08-05 | DSM IP Assets B.V. | Acetic acid consuming strain |
| CA3077115A1 (en) | 2017-09-29 | 2019-04-04 | Dsm Ip Assets B.V. | Improved glycerol free ethanol production |
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| MX2020008309A (es) * | 2018-02-15 | 2020-10-14 | Novozymes As | Levadura mejorada para produccion de etanol. |
| RS65389B1 (sr) | 2018-03-06 | 2024-04-30 | Danisco Us Inc | Smanjenje proizvodnje acetata kod kvasaca koji prekomerno eksprimiraju pab1 |
| WO2019173225A1 (en) * | 2018-03-06 | 2019-09-12 | Danisco Us Inc | Yeast with improved alcohol production under high dissolved solids conditions |
| US20210047660A1 (en) | 2018-03-06 | 2021-02-18 | Danisco Us Inc. | Compositions and methods for increasing ethanol production by yeast using gcy1 and dak1 |
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| BR112022007870A2 (pt) | 2019-11-08 | 2022-07-12 | Dsm Ip Assets Bv | Processo para produzir etanol |
| MX2022006340A (es) | 2019-11-26 | 2022-10-07 | Danisco Us Inc | Reducción de la producción de acetato mediante una levadura que sobreexpresa polipéptidos mig. |
| US20230116556A1 (en) | 2020-01-23 | 2023-04-13 | Danisco Us Inc. | Increased ethanol production by overexpression of jid1 in yeast |
| US20230374443A1 (en) | 2020-10-05 | 2023-11-23 | Dsm Ip Assets B.V. | Saccharomyces yeast cell and fermentation process using such |
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| CN117916381A (zh) | 2021-07-12 | 2024-04-19 | 丹尼斯科美国公司 | 重组酵母细胞 |
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| MX2024005281A (es) | 2021-11-04 | 2024-05-17 | Danisco Us Inc | Celula de levadura recombinante. |
| US20240425888A1 (en) | 2021-11-04 | 2024-12-26 | Danisco Us Inc. | Process for the production of ethanol and recombinant yeast cell |
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| US7026463B2 (en) | 1999-08-13 | 2006-04-11 | Matthew Glenn | Polynucleotides and polypeptides, materials incorporating them and methods for using them |
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| FR2807446B1 (fr) | 2000-04-11 | 2005-05-06 | Agronomique Inst Nat Rech | Genomes de lactococcus lactis, polypeptides et utilisations |
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| WO2002094867A2 (fr) | 2001-02-07 | 2002-11-28 | Institut Pasteur | Sequence du genome de photorhabdus luminescens souche tto1 et utilisations |
| US7253001B2 (en) | 2002-03-19 | 2007-08-07 | Forskarpatent I Syd Ab | Metabolic engineering for improved xylose utilisation of Saccharomyces cerevisiae |
| SE0200857D0 (sv) * | 2002-03-19 | 2002-03-19 | Forskarpatent I Syd Ab | Metabolic engineering for improved xylose utilisation of saccharomyces cerevisiae |
| JP4372408B2 (ja) | 2002-11-14 | 2009-11-25 | 三菱レイヨン株式会社 | ロドコッカス（Ｒｈｏｄｏｃｏｃｃｕｓ）属細菌組換え体、及びそれを用いた光学活性体の製造方法 |
| GB0227435D0 (en) * | 2002-11-25 | 2002-12-31 | Univ Denmark Tech Dtu | Metabolically engineered micro-organisms having reduced production of undesired metobolic products |
| WO2004085627A1 (en) | 2003-03-26 | 2004-10-07 | Forskarpatent I Syd Ab | New saccharomyces cerevisiae strains utilizing xylose |
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| BRPI0614990A2 (pt) | 2005-08-19 | 2011-04-26 | Univ California | células hospedeiras geneticamente modificadas e uso das mesmas para produção de compostos isoprenóides |
| EP1948814B1 (en) | 2005-10-26 | 2018-11-21 | Butamax (TM) Advanced Biofuels LLC | Fermentive production of four carbon alcohols |
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| DE102008004253B4 (de) * | 2008-01-14 | 2011-07-28 | Butalco Gmbh | Gesteigerte Produktion von Acetyl-Coenzym A |
| WO2009113101A2 (en) | 2008-02-20 | 2009-09-17 | Nagarjuna Fertilizers And Chemicals Limited | Genetically transformed microorganisms with simultaneous enhancement of reduction potential and reductive enzyme activities for biomass fermentation |
| SI2262901T1 (sl) * | 2008-03-05 | 2019-02-28 | Genomatica, Inc. | Primarni alkohol producirajoči organizmi |
| EP2277989A1 (en) * | 2009-07-24 | 2011-01-26 | Technische Universiteit Delft | Fermentative glycerol-free ethanol production |
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2009
- 2009-07-24 EP EP09166360A patent/EP2277989A1/en not_active Withdrawn
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2010
- 2010-07-23 MX MX2012001062A patent/MX2012001062A/es active IP Right Grant
- 2010-07-23 EP EP20217514.7A patent/EP3828261A1/en active Pending
- 2010-07-23 JP JP2012521593A patent/JP5836271B2/ja active Active
- 2010-07-23 BR BR112012001642A patent/BR112012001642B1/pt active IP Right Grant
- 2010-07-23 DK DK10740412.1T patent/DK2456851T3/en active
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- 2010-07-23 CA CA2768897A patent/CA2768897C/en active Active
- 2010-07-23 CN CN201080042861.6A patent/CN102712895B/zh active Active
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