JP2013155195A5 - - Google Patents
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- JP2013155195A5 JP2013155195A5 JP2013099331A JP2013099331A JP2013155195A5 JP 2013155195 A5 JP2013155195 A5 JP 2013155195A5 JP 2013099331 A JP2013099331 A JP 2013099331A JP 2013099331 A JP2013099331 A JP 2013099331A JP 2013155195 A5 JP2013155195 A5 JP 2013155195A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- cysteine
- peptide
- compound
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22969509P | 2009-07-29 | 2009-07-29 | |
| US61/229,695 | 2009-07-29 | ||
| US25581609P | 2009-10-28 | 2009-10-28 | |
| US61/255,816 | 2009-10-28 | ||
| US31363510P | 2010-03-12 | 2010-03-12 | |
| US61/313,635 | 2010-03-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523061A Division JP5270799B2 (ja) | 2009-07-29 | 2010-07-29 | 副甲状腺ホルモンを低減する治療剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014023488A Division JP2014094967A (ja) | 2009-07-29 | 2014-02-10 | 副甲状腺ホルモンを低減する治療剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013155195A JP2013155195A (ja) | 2013-08-15 |
| JP2013155195A5 true JP2013155195A5 (enExample) | 2014-03-27 |
| JP5764613B2 JP5764613B2 (ja) | 2015-08-19 |
Family
ID=43527590
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523061A Active JP5270799B2 (ja) | 2009-07-29 | 2010-07-29 | 副甲状腺ホルモンを低減する治療剤 |
| JP2013099331A Active JP5764613B2 (ja) | 2009-07-29 | 2013-05-09 | 副甲状腺ホルモンを低減する治療剤 |
| JP2014023488A Pending JP2014094967A (ja) | 2009-07-29 | 2014-02-10 | 副甲状腺ホルモンを低減する治療剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523061A Active JP5270799B2 (ja) | 2009-07-29 | 2010-07-29 | 副甲状腺ホルモンを低減する治療剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014023488A Pending JP2014094967A (ja) | 2009-07-29 | 2014-02-10 | 副甲状腺ホルモンを低減する治療剤 |
Country Status (29)
| Country | Link |
|---|---|
| US (11) | US8999932B2 (enExample) |
| EP (5) | EP4154900B1 (enExample) |
| JP (3) | JP5270799B2 (enExample) |
| KR (1) | KR101781841B1 (enExample) |
| CN (2) | CN102711789B (enExample) |
| AU (1) | AU2010278897B2 (enExample) |
| BR (1) | BR112012002143B8 (enExample) |
| CA (1) | CA2769525C (enExample) |
| CY (3) | CY1118388T1 (enExample) |
| DK (2) | DK3192520T3 (enExample) |
| ES (2) | ES2607954T3 (enExample) |
| FR (1) | FR17C1009I2 (enExample) |
| HR (2) | HRP20161614T1 (enExample) |
| HU (3) | HUE043838T2 (enExample) |
| IL (1) | IL217749A (enExample) |
| LT (3) | LT3192520T (enExample) |
| LU (1) | LUC00008I2 (enExample) |
| MX (1) | MX2012001213A (enExample) |
| NO (1) | NO2017021I1 (enExample) |
| NZ (1) | NZ597922A (enExample) |
| PL (2) | PL2459208T3 (enExample) |
| PT (2) | PT3192520T (enExample) |
| RU (1) | RU2557654C3 (enExample) |
| SG (2) | SG178143A1 (enExample) |
| SI (2) | SI3192520T1 (enExample) |
| SM (3) | SMT201700014B (enExample) |
| TW (1) | TWI520744B (enExample) |
| WO (1) | WO2011014707A2 (enExample) |
| ZA (1) | ZA201200726B (enExample) |
Families Citing this family (33)
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| CA2669914C (en) * | 2006-11-16 | 2017-11-07 | Kai Pharmaceuticals, Inc. | Polycationic calcium modulator peptides for the treatment of hyperparathyroidism and hypercalcemic disorders |
| LT3192520T (lt) | 2009-07-29 | 2019-06-25 | Kai Pharmaceuticals, Inc. | Terapiniai agentai, skirti paratiroidinio hormono lygių sumažinimui |
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| CN102781910B (zh) | 2010-03-04 | 2015-03-11 | 味之素株式会社 | 烷基胺衍生物 |
| JP5796570B2 (ja) | 2010-03-24 | 2015-10-21 | 味の素株式会社 | グルタミン酸エステル誘導体又はその塩 |
| EP2554165A4 (en) | 2010-04-02 | 2014-04-30 | Ajinomoto Kk | PROPHYLACTIC OR THERAPEUTIC ACTIVE AGAINST DIABETES OR ADIPOSITAS |
| SI2717896T1 (sl) * | 2011-06-08 | 2017-04-26 | Kai Pharmaceuticals, Inc. | Terapevtska sredstva za reguliranje serumskega fosforja |
| MX355063B (es) | 2011-11-10 | 2018-04-04 | Kai Pharmaceuticals Inc | Calcimiméticos y métodos para su uso. |
| US20150126457A1 (en) * | 2012-04-17 | 2015-05-07 | Brown University | Neuroprotective composition and method of use |
| US20200354428A9 (en) | 2013-06-23 | 2020-11-12 | Wisconsin Alumni Research Foundation | Analogues of parathyroid hormone (1-34) that function as agonists of the parathyroid hormone receptor-1 and display modified activity profiles |
| EP3246017B1 (en) * | 2013-06-28 | 2021-03-24 | Amgen Inc. | Stable liquid formulation of amg 416 hcl (etelcalcetide) |
| ME03781B (me) * | 2014-04-03 | 2021-04-20 | Amgen Inc | Metoda za pripremanje amg 416 |
| CN105504012A (zh) * | 2014-09-30 | 2016-04-20 | 深圳翰宇药业股份有限公司 | 一种多肽的制备方法 |
| US9616109B2 (en) | 2014-10-22 | 2017-04-11 | Extend Biosciences, Inc. | Insulin vitamin D conjugates |
| CA2964463C (en) | 2014-10-22 | 2024-02-13 | Extend Biosciences, Inc. | Therapeutic vitamin d conjugates |
| EP3274360B1 (en) | 2015-03-26 | 2020-05-06 | Amgen Inc. | Solution phase method for preparing etelcalcetide |
| US9336841B1 (en) * | 2015-04-16 | 2016-05-10 | Taiwan Semiconductor Manufacturing Co., Ltd. | Pipeline register with data alignment therein |
| CN106928320B (zh) * | 2015-12-31 | 2021-01-15 | 深圳翰宇药业股份有限公司 | 一种合成Etelcalcetide的方法 |
| CN106928321B (zh) * | 2015-12-31 | 2019-07-26 | 深圳翰宇药业股份有限公司 | 一种合成Etelcalcetide的方法 |
| US10105375B2 (en) | 2016-08-30 | 2018-10-23 | Wisconsin Alumni Research Foundation | Combination of low dose 2-methylene-19-nor-(20S)1α, 25-dihydroxyvitamin D3 and calcimimetics to treat secondary hyperparathyroidism |
| JP2021501793A (ja) * | 2017-11-07 | 2021-01-21 | アルファコア ファーマ リミテッド ライアビリティ カンパニーAlphacore Pharma Llc | 心疾患、心血管疾患及び関連する病状と症状を治療し保護する方法 |
| WO2019124411A1 (ja) | 2017-12-20 | 2019-06-27 | Eaファーマ株式会社 | 維持透析下の二次性副甲状腺機能亢進症の予防または治療用医薬組成物 |
| KR101933685B1 (ko) * | 2018-06-29 | 2018-12-28 | 주식회사 에스알바이오텍 | 약물이 코팅된 마이크로 니들 및 이의 제조방법 |
| EP3906059A4 (en) * | 2018-11-02 | 2022-06-22 | Ampersand Biopharmaceuticals, Inc. | MANAGING THE RISK OF CATION OVERLOAD AND ELECTROLYTE BALANCE WITH TOPICALLY APPLIED BUFFER |
| EP3950058A4 (en) | 2019-04-03 | 2023-01-04 | EA Pharma Co., Ltd. | PHARMACEUTICAL COMPOSITION WITH FAVORABLE STABILITY |
| WO2021115272A1 (zh) * | 2019-12-09 | 2021-06-17 | 北京拓界生物医药科技有限公司 | 钙敏感受体激动剂化合物及其应用 |
| WO2021226064A1 (en) * | 2020-05-04 | 2021-11-11 | University Of Louisville Research Foundation, Inc. | Artificial intelligence-based systems and methods for dosing of pharmacologic agents |
| JP7440132B2 (ja) * | 2020-09-10 | 2024-02-28 | シャンシー・ミコ・テクノロジー・カンパニー・リミテッド | 二重特異性融合ポリペプチド化合物 |
| US11359134B2 (en) | 2020-10-19 | 2022-06-14 | Saudi Arabian Oil Company | Treatment fluids and methods for recovering hydrocarbons from a subterranean formation |
| TW202247854A (zh) * | 2021-06-08 | 2022-12-16 | 大陸商北京拓界生物醫藥科技有限公司 | 一種鈣敏感受體激動劑的組成物及其應用 |
| CN117500820A (zh) * | 2021-06-08 | 2024-02-02 | 北京拓界生物医药科技有限公司 | 钙敏感受体激动剂化合物的盐酸盐及药物组合物和其应用 |
| KR20250075704A (ko) | 2022-09-30 | 2025-05-28 | 익스텐드 바이오사이언시즈, 인크. | 장기-지속형 부갑상선 호르몬 |
| WO2025054169A1 (en) * | 2023-09-05 | 2025-03-13 | Wake Forest University Health Sciences | Compositions and methods for topical treatment |
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| MX355063B (es) | 2011-11-10 | 2018-04-04 | Kai Pharmaceuticals Inc | Calcimiméticos y métodos para su uso. |
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2010
- 2010-07-29 LT LTEP16190682.1T patent/LT3192520T/lt unknown
- 2010-07-29 AU AU2010278897A patent/AU2010278897B2/en active Active
- 2010-07-29 JP JP2012523061A patent/JP5270799B2/ja active Active
- 2010-07-29 SM SM201700014T patent/SMT201700014B/it unknown
- 2010-07-29 EP EP22193946.5A patent/EP4154900B1/en active Active
- 2010-07-29 CN CN201080045024.9A patent/CN102711789B/zh active Active
- 2010-07-29 EP EP19159337.5A patent/EP3539555B1/en active Active
- 2010-07-29 DK DK16190682.1T patent/DK3192520T3/da active
- 2010-07-29 BR BR112012002143A patent/BR112012002143B8/pt active IP Right Grant
- 2010-07-29 HU HUE16190682A patent/HUE043838T2/hu unknown
- 2010-07-29 CN CN201710873189.9A patent/CN107674114B/zh active Active
- 2010-07-29 HR HRP20161614TT patent/HRP20161614T1/hr unknown
- 2010-07-29 TW TW099125105A patent/TWI520744B/zh active
- 2010-07-29 ES ES10805078.2T patent/ES2607954T3/es active Active
- 2010-07-29 NZ NZ597922A patent/NZ597922A/en unknown
- 2010-07-29 DK DK10805078.2T patent/DK2459208T3/en active
- 2010-07-29 ES ES16190682T patent/ES2729051T3/es active Active
- 2010-07-29 PT PT16190682T patent/PT3192520T/pt unknown
- 2010-07-29 PT PT108050782T patent/PT2459208T/pt unknown
- 2010-07-29 SM SM20190307T patent/SMT201900307T1/it unknown
- 2010-07-29 CA CA2769525A patent/CA2769525C/en active Active
- 2010-07-29 KR KR1020127004785A patent/KR101781841B1/ko active Active
- 2010-07-29 EP EP16190682.1A patent/EP3192520B1/en active Active
- 2010-07-29 US US12/846,724 patent/US8999932B2/en active Active
- 2010-07-29 PL PL10805078T patent/PL2459208T3/pl unknown
- 2010-07-29 HU HUE10805078A patent/HUE030960T2/en unknown
- 2010-07-29 SI SI201031894T patent/SI3192520T1/sl unknown
- 2010-07-29 SG SG2012006185A patent/SG178143A1/en unknown
- 2010-07-29 MX MX2012001213A patent/MX2012001213A/es active IP Right Grant
- 2010-07-29 LT LTEP10805078.2T patent/LT2459208T/lt unknown
- 2010-07-29 SG SG10201406921SA patent/SG10201406921SA/en unknown
- 2010-07-29 EP EP20209086.6A patent/EP3808363B1/en active Active
- 2010-07-29 RU RU2012107428A patent/RU2557654C3/ru active
- 2010-07-29 SM SM20170014T patent/SMT201700014T1/it unknown
- 2010-07-29 WO PCT/US2010/043792 patent/WO2011014707A2/en not_active Ceased
- 2010-07-29 PL PL16190682T patent/PL3192520T3/pl unknown
- 2010-07-29 EP EP10805078.2A patent/EP2459208B1/en active Active
- 2010-07-29 SI SI201031337A patent/SI2459208T1/sl unknown
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2012
- 2012-01-26 IL IL217749A patent/IL217749A/en active Protection Beyond IP Right Term
- 2012-01-30 ZA ZA2012/00726A patent/ZA201200726B/en unknown
- 2012-02-02 US US13/365,213 patent/US8377880B2/en active Active
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2013
- 2013-02-18 US US13/769,744 patent/US9278995B2/en active Active
- 2013-05-09 JP JP2013099331A patent/JP5764613B2/ja active Active
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2014
- 2014-02-10 JP JP2014023488A patent/JP2014094967A/ja active Pending
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2015
- 2015-03-04 US US14/639,020 patent/US9567370B2/en active Active
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2016
- 2016-02-08 US US15/018,567 patent/US9701712B2/en active Active
- 2016-12-27 CY CY20161101349T patent/CY1118388T1/el unknown
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2017
- 2017-01-09 US US15/402,133 patent/US20170114095A1/en not_active Abandoned
- 2017-03-01 HU HUS1700008 patent/HUS1700008I1/hu unknown
- 2017-03-09 LU LU00008C patent/LUC00008I2/fr unknown
- 2017-03-10 LT LTPA2017007C patent/LTC2459208I2/lt unknown
- 2017-03-16 CY CY2017010C patent/CY2017010I1/el unknown
- 2017-03-17 FR FR17C1009C patent/FR17C1009I2/fr active Active
- 2017-05-05 NO NO2017021C patent/NO2017021I1/no unknown
- 2017-06-21 US US15/629,536 patent/US10280198B2/en active Active
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2019
- 2019-03-11 US US16/298,902 patent/US20190194252A1/en not_active Abandoned
- 2019-05-17 HR HRP20190923TT patent/HRP20190923T1/hr unknown
- 2019-05-31 CY CY20191100579T patent/CY1121922T1/el unknown
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2020
- 2020-09-02 US US17/010,773 patent/US20200399309A1/en not_active Abandoned
-
2022
- 2022-10-04 US US17/960,060 patent/US20240116983A1/en not_active Abandoned
-
2025
- 2025-01-16 US US19/025,984 patent/US20250163103A1/en active Pending
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