LUC00008I2 - - Google Patents

Info

Publication number
LUC00008I2
LUC00008I2 LU00008C LUC00008C LUC00008I2 LU C00008 I2 LUC00008 I2 LU C00008I2 LU 00008 C LU00008 C LU 00008C LU C00008 C LUC00008 C LU C00008C LU C00008 I2 LUC00008 I2 LU C00008I2
Authority
LU
Luxembourg
Application number
LU00008C
Other languages
French (fr)
Original Assignee
Kai Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43527590&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LUC00008(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kai Pharmaceuticals Inc filed Critical Kai Pharmaceuticals Inc
Publication of LUC00008I1 publication Critical patent/LUC00008I1/fr
Publication of LUC00008I2 publication Critical patent/LUC00008I2/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LU00008C 2009-07-29 2017-03-09 LUC00008I2 (enExample)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22969509P 2009-07-29 2009-07-29
US25581609P 2009-10-28 2009-10-28
US31363510P 2010-03-12 2010-03-12
PCT/US2010/043792 WO2011014707A2 (en) 2009-07-29 2010-07-29 Therapeutic agents for reducing parathyroid hormone levels

Publications (2)

Publication Number Publication Date
LUC00008I1 LUC00008I1 (enExample) 2017-03-16
LUC00008I2 true LUC00008I2 (enExample) 2017-05-30

Family

ID=43527590

Family Applications (1)

Application Number Title Priority Date Filing Date
LU00008C LUC00008I2 (enExample) 2009-07-29 2017-03-09

Country Status (29)

Country Link
US (11) US8999932B2 (enExample)
EP (5) EP3539555B1 (enExample)
JP (3) JP5270799B2 (enExample)
KR (1) KR101781841B1 (enExample)
CN (2) CN107674114B (enExample)
AU (1) AU2010278897B2 (enExample)
BR (1) BR112012002143B8 (enExample)
CA (1) CA2769525C (enExample)
CY (3) CY1118388T1 (enExample)
DK (2) DK3192520T3 (enExample)
ES (2) ES2607954T3 (enExample)
FR (1) FR17C1009I2 (enExample)
HR (2) HRP20161614T1 (enExample)
HU (3) HUE030960T2 (enExample)
IL (1) IL217749A (enExample)
LT (3) LT2459208T (enExample)
LU (1) LUC00008I2 (enExample)
MX (1) MX2012001213A (enExample)
NO (1) NO2017021I1 (enExample)
NZ (1) NZ597922A (enExample)
PL (2) PL3192520T3 (enExample)
PT (2) PT3192520T (enExample)
RU (1) RU2557654C3 (enExample)
SG (2) SG178143A1 (enExample)
SI (2) SI3192520T1 (enExample)
SM (3) SMT201700014T1 (enExample)
TW (1) TWI520744B (enExample)
WO (1) WO2011014707A2 (enExample)
ZA (1) ZA201200726B (enExample)

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CA2791174C (en) 2010-03-04 2015-11-17 Ajinomoto Co., Inc. Alkylamine derivative
WO2011118843A1 (ja) 2010-03-24 2011-09-29 味の素株式会社 グルタミン酸エステル誘導体又はその塩
WO2011126099A1 (ja) 2010-04-02 2011-10-13 味の素株式会社 糖尿病又は肥満症の予防又は治療剤
HRP20161566T1 (hr) * 2011-06-08 2017-02-24 Kai Pharmaceuticals, Inc. Terapijski agensi za reguliranje serumskog fosfora
AU2012335009B2 (en) * 2011-11-10 2017-08-31 Kai Pharmaceuticals, Inc. Calcimimetics and methods for their use
WO2013158739A1 (en) 2012-04-17 2013-10-24 Brown University Neuroprotective composition and method of use
US20200354428A9 (en) 2013-06-23 2020-11-12 Wisconsin Alumni Research Foundation Analogues of parathyroid hormone (1-34) that function as agonists of the parathyroid hormone receptor-1 and display modified activity profiles
SI3013318T1 (sl) * 2013-06-28 2017-11-30 Amgen Inc. Stabilna tekoča oblika amg 416 (velkalcetid)
ES2786225T3 (es) * 2014-04-03 2020-10-09 Amgen Inc Método para preparar AMG 416
CN105504012A (zh) * 2014-09-30 2016-04-20 深圳翰宇药业股份有限公司 一种多肽的制备方法
WO2016065052A1 (en) 2014-10-22 2016-04-28 Extend Biosciences, Inc. Insulin vitamin d conjugates
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US9336841B1 (en) * 2015-04-16 2016-05-10 Taiwan Semiconductor Manufacturing Co., Ltd. Pipeline register with data alignment therein
CN106928320B (zh) 2015-12-31 2021-01-15 深圳翰宇药业股份有限公司 一种合成Etelcalcetide的方法
CN106928321B (zh) * 2015-12-31 2019-07-26 深圳翰宇药业股份有限公司 一种合成Etelcalcetide的方法
US10105375B2 (en) 2016-08-30 2018-10-23 Wisconsin Alumni Research Foundation Combination of low dose 2-methylene-19-nor-(20S)1α, 25-dihydroxyvitamin D3 and calcimimetics to treat secondary hyperparathyroidism
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KR101933685B1 (ko) * 2018-06-29 2018-12-28 주식회사 에스알바이오텍 약물이 코팅된 마이크로 니들 및 이의 제조방법
WO2020093069A1 (en) * 2018-11-02 2020-05-07 Ampersand Biopharmaceuticals, Inc. Management of risk of cation overload and electrolyte imbalance with topically applied buffers
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US20230223125A1 (en) * 2020-05-04 2023-07-13 University Of Louisville Research Foundation, Inc. Artificial intelligence-based systems and methods for dosing of pharmacologic agents
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SMT201700014T1 (it) 2009-07-29 2017-03-08 Kai Pharmaceuticals Inc Agenti terapeutici per la riduzione dei livelli dell'ormone paratiroideo
HRP20161566T1 (hr) * 2011-06-08 2017-02-24 Kai Pharmaceuticals, Inc. Terapijski agensi za reguliranje serumskog fosfora
AU2012335009B2 (en) 2011-11-10 2017-08-31 Kai Pharmaceuticals, Inc. Calcimimetics and methods for their use

Also Published As

Publication number Publication date
NO2017021I1 (no) 2017-05-05
BR112012002143B1 (pt) 2020-12-08
CY2017010I2 (el) 2017-11-14
TW201116290A (en) 2011-05-16
LTPA2017007I1 (lt) 2017-03-27
HUE030960T2 (en) 2017-06-28
JP5270799B2 (ja) 2013-08-21
US20180022777A1 (en) 2018-01-25
SMT201700014B (it) 2017-03-08
US9278995B2 (en) 2016-03-08
EP3192520A1 (en) 2017-07-19
US20250163103A1 (en) 2025-05-22
EP4154900B1 (en) 2024-08-28
EP3539555A1 (en) 2019-09-18
FR17C1009I2 (fr) 2019-04-12
FR17C1009I1 (enExample) 2017-04-21
RU2557654C2 (ru) 2015-07-27
PL2459208T3 (pl) 2017-05-31
LUC00008I1 (enExample) 2017-03-16
JP2014094967A (ja) 2014-05-22
EP3539555B1 (en) 2020-12-30
CN107674114A (zh) 2018-02-09
JP2013500990A (ja) 2013-01-10
US20160159860A1 (en) 2016-06-09
CA2769525C (en) 2017-02-21
KR20120104513A (ko) 2012-09-21
US20110028394A1 (en) 2011-02-03
HRP20161614T1 (hr) 2017-02-24
EP3192520B1 (en) 2019-03-06
SMT201700014T1 (it) 2017-03-08
AU2010278897A1 (en) 2012-02-23
IL217749A (en) 2016-09-29
PT2459208T (pt) 2017-01-03
RU2012107428A (ru) 2013-09-10
HUS1700008I1 (hu) 2017-04-28
AU2010278897B2 (en) 2015-02-26
US20190194252A1 (en) 2019-06-27
BR112012002143B8 (pt) 2021-05-25
EP2459208A4 (en) 2014-06-04
DK3192520T3 (da) 2019-05-27
MX2012001213A (es) 2012-06-12
TWI520744B (zh) 2016-02-11
ZA201200726B (en) 2013-05-29
ES2729051T3 (es) 2019-10-30
CY1118388T1 (el) 2017-06-28
PT3192520T (pt) 2019-06-12
US20170114095A1 (en) 2017-04-27
EP4154900A1 (en) 2023-03-29
PL3192520T3 (pl) 2019-08-30
US9701712B2 (en) 2017-07-11
US20200399309A1 (en) 2020-12-24
CY2017010I1 (el) 2017-11-14
SI3192520T1 (sl) 2019-08-30
US8999932B2 (en) 2015-04-07
EP3808363A1 (en) 2021-04-21
US20130150297A1 (en) 2013-06-13
WO2011014707A3 (en) 2011-07-07
CN102711789A (zh) 2012-10-03
IL217749A0 (en) 2012-03-29
SI2459208T1 (sl) 2017-04-26
DK2459208T3 (en) 2017-01-23
EP2459208B1 (en) 2016-09-28
CY1121922T1 (el) 2020-10-14
US10280198B2 (en) 2019-05-07
CN102711789B (zh) 2018-06-08
NZ597922A (en) 2015-01-30
US20120178688A1 (en) 2012-07-12
RU2557654C3 (ru) 2017-07-05
LT3192520T (lt) 2019-06-25
EP2459208A2 (en) 2012-06-06
BR112012002143A2 (pt) 2016-11-08
SMT201900307T1 (it) 2019-07-11
EP3808363B1 (en) 2022-09-07
HRP20190923T1 (hr) 2019-10-04
US20150175664A1 (en) 2015-06-25
US20240116983A1 (en) 2024-04-11
US9567370B2 (en) 2017-02-14
SG10201406921SA (en) 2014-11-27
HK1167108A1 (zh) 2012-11-23
JP5764613B2 (ja) 2015-08-19
LTC2459208I2 (lt) 2021-07-12
HUE043838T2 (hu) 2019-09-30
CN107674114B (zh) 2022-10-25
WO2011014707A2 (en) 2011-02-03
SG178143A1 (en) 2012-03-29
US8377880B2 (en) 2013-02-19
CA2769525A1 (en) 2011-02-03
JP2013155195A (ja) 2013-08-15
LT2459208T (lt) 2017-02-27
ES2607954T3 (es) 2017-04-04
KR101781841B1 (ko) 2017-09-26

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