HUS1700008I1 - Terápiás szerek a mellékpajzsmirigy-hormon szintjének csökkentésére - Google Patents
Terápiás szerek a mellékpajzsmirigy-hormon szintjének csökkentéséreInfo
- Publication number
- HUS1700008I1 HUS1700008I1 HUS1700008C HUS1700008I1 HU S1700008 I1 HUS1700008 I1 HU S1700008I1 HU S1700008 C HUS1700008 C HU S1700008C HU S1700008 I1 HUS1700008 I1 HU S1700008I1
- Authority
- HU
- Hungary
- Prior art keywords
- therapeutic agents
- parathyroid hormone
- hormone levels
- reducing parathyroid
- reducing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22969509P | 2009-07-29 | 2009-07-29 | |
| US25581609P | 2009-10-28 | 2009-10-28 | |
| US31363510P | 2010-03-12 | 2010-03-12 | |
| EP10805078.2A EP2459208B1 (en) | 2009-07-29 | 2010-07-29 | Therapeutic agents for reducing parathyroid hormone levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUS1700008I1 true HUS1700008I1 (hu) | 2017-04-28 |
Family
ID=43527590
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16190682A HUE043838T2 (hu) | 2009-07-29 | 2010-07-29 | Mellékpajzsmirigy-hormonszintek csökkentésére szolgáló terápiás szerek |
| HUE10805078A HUE030960T2 (hu) | 2009-07-29 | 2010-07-29 | Terápiás szerek a mellékpajzsmirigy-hormon szintjének csökkentésére |
| HUS1700008 HUS1700008I1 (hu) | 2009-07-29 | 2017-03-01 | Terápiás szerek a mellékpajzsmirigy-hormon szintjének csökkentésére |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16190682A HUE043838T2 (hu) | 2009-07-29 | 2010-07-29 | Mellékpajzsmirigy-hormonszintek csökkentésére szolgáló terápiás szerek |
| HUE10805078A HUE030960T2 (hu) | 2009-07-29 | 2010-07-29 | Terápiás szerek a mellékpajzsmirigy-hormon szintjének csökkentésére |
Country Status (30)
| Country | Link |
|---|---|
| US (10) | US8999932B2 (hu) |
| EP (5) | EP3192520B1 (hu) |
| JP (3) | JP5270799B2 (hu) |
| KR (1) | KR101781841B1 (hu) |
| CN (2) | CN102711789B (hu) |
| AU (1) | AU2010278897B2 (hu) |
| BR (1) | BR112012002143B8 (hu) |
| CA (1) | CA2769525C (hu) |
| CY (3) | CY1118388T1 (hu) |
| DK (2) | DK2459208T3 (hu) |
| ES (2) | ES2729051T3 (hu) |
| FR (1) | FR17C1009I2 (hu) |
| HK (1) | HK1167108A1 (hu) |
| HR (2) | HRP20161614T1 (hu) |
| HU (3) | HUE043838T2 (hu) |
| IL (1) | IL217749A (hu) |
| LT (3) | LT3192520T (hu) |
| LU (1) | LUC00008I2 (hu) |
| MX (1) | MX2012001213A (hu) |
| NO (1) | NO2017021I1 (hu) |
| NZ (1) | NZ597922A (hu) |
| PL (2) | PL3192520T3 (hu) |
| PT (2) | PT2459208T (hu) |
| RU (1) | RU2557654C3 (hu) |
| SG (2) | SG10201406921SA (hu) |
| SI (2) | SI2459208T1 (hu) |
| SM (1) | SMT201700014B (hu) |
| TW (1) | TWI520744B (hu) |
| WO (1) | WO2011014707A2 (hu) |
| ZA (1) | ZA201200726B (hu) |
Families Citing this family (31)
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| KR101552843B1 (ko) | 2006-11-16 | 2015-09-14 | 카이 파마슈티컬즈 | 부갑상선 기능항진증 및 고칼슘혈증 장애의 치료를 위한 폴리양이온성 칼슘 조절제 펩타이드 |
| SG10201406921SA (en) | 2009-07-29 | 2014-11-27 | Kai Pharmaceuticals Inc | Therapeutic agents for reducing parathyroid hormone levels |
| PL2546231T3 (pl) | 2010-03-04 | 2019-05-31 | Ea Pharma Co Ltd | Pochodna alkiloaminy |
| JP5761173B2 (ja) | 2010-03-04 | 2015-08-12 | 味の素株式会社 | 糖尿病又は肥満症の予防又は治療剤 |
| JP5796570B2 (ja) | 2010-03-24 | 2015-10-21 | 味の素株式会社 | グルタミン酸エステル誘導体又はその塩 |
| JPWO2011126099A1 (ja) | 2010-04-02 | 2013-07-11 | 味の素株式会社 | 糖尿病又は肥満症の予防又は治療剤 |
| CN103857405B (zh) * | 2011-06-08 | 2015-12-02 | 凯伊药品公司 | 用于调节血清磷的治疗剂 |
| AU2012335009B2 (en) * | 2011-11-10 | 2017-08-31 | Kai Pharmaceuticals, Inc. | Calcimimetics and methods for their use |
| JP2015514771A (ja) | 2012-04-17 | 2015-05-21 | ブラウン ユニバーシティ | 神経保護性組成物および使用方法 |
| US20200354428A9 (en) | 2013-06-23 | 2020-11-12 | Wisconsin Alumni Research Foundation | Analogues of parathyroid hormone (1-34) that function as agonists of the parathyroid hormone receptor-1 and display modified activity profiles |
| SG11201510647TA (en) | 2013-06-28 | 2016-01-28 | Amgen Inc | Stable liquid formulation of amg 416 (velcalcetide) |
| EP3708576B1 (en) * | 2014-04-03 | 2023-02-22 | Amgen Inc. | Method for preparing amg 416 |
| CN105504012A (zh) * | 2014-09-30 | 2016-04-20 | 深圳翰宇药业股份有限公司 | 一种多肽的制备方法 |
| US9585934B2 (en) | 2014-10-22 | 2017-03-07 | Extend Biosciences, Inc. | Therapeutic vitamin D conjugates |
| US9616109B2 (en) | 2014-10-22 | 2017-04-11 | Extend Biosciences, Inc. | Insulin vitamin D conjugates |
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| US9336841B1 (en) * | 2015-04-16 | 2016-05-10 | Taiwan Semiconductor Manufacturing Co., Ltd. | Pipeline register with data alignment therein |
| CN106928321B (zh) * | 2015-12-31 | 2019-07-26 | 深圳翰宇药业股份有限公司 | 一种合成Etelcalcetide的方法 |
| CN106928320B (zh) * | 2015-12-31 | 2021-01-15 | 深圳翰宇药业股份有限公司 | 一种合成Etelcalcetide的方法 |
| US10105375B2 (en) | 2016-08-30 | 2018-10-23 | Wisconsin Alumni Research Foundation | Combination of low dose 2-methylene-19-nor-(20S)1α, 25-dihydroxyvitamin D3 and calcimimetics to treat secondary hyperparathyroidism |
| CN111601614A (zh) * | 2017-11-07 | 2020-08-28 | 阿尔法科制药有限责任公司 | 治疗和预防心脏病、心血管疾病及相关病症和症状的方法 |
| BR112020012004A2 (pt) | 2017-12-20 | 2020-11-17 | Ea Pharma Co., Ltd. | composição medicinal para prevenir ou tratar hiperparatireoidismo secundário em diálise de manutenção, e, uso de uma composição medicinal campo da invenção |
| KR101933685B1 (ko) * | 2018-06-29 | 2018-12-28 | 주식회사 에스알바이오텍 | 약물이 코팅된 마이크로 니들 및 이의 제조방법 |
| US20210369769A1 (en) * | 2018-11-02 | 2021-12-02 | Dyve Biosciences, Inc. | Management of risk of cation overload and electrolyte imbalance with topically applied buffers |
| CN113260416A (zh) | 2019-04-03 | 2021-08-13 | Ea制药株式会社 | 稳定性良好的医药组合物 |
| AU2020399030A1 (en) * | 2019-12-09 | 2022-06-23 | Beijing Tuo Jie Biopharmaceutical Co. Ltd. | Calcium-sensing receptor agonist compound and application thereof |
| WO2021226064A1 (en) * | 2020-05-04 | 2021-11-11 | University Of Louisville Research Foundation, Inc. | Artificial intelligence-based systems and methods for dosing of pharmacologic agents |
| CA3194729A1 (en) * | 2020-09-10 | 2022-03-17 | Shaanxi Micot Technology Co., Ltd. | Bispecific fusion polypeptide compound |
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| TW202313655A (zh) * | 2021-06-08 | 2023-04-01 | 大陸商北京拓界生物醫藥科技有限公司 | 鈣敏感受體激動劑化合物的鹽酸鹽及醫藥組成物和其應用 |
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