JP2012506408A5 - - Google Patents
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- Publication number
- JP2012506408A5 JP2012506408A5 JP2011532704A JP2011532704A JP2012506408A5 JP 2012506408 A5 JP2012506408 A5 JP 2012506408A5 JP 2011532704 A JP2011532704 A JP 2011532704A JP 2011532704 A JP2011532704 A JP 2011532704A JP 2012506408 A5 JP2012506408 A5 JP 2012506408A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- group
- terminus
- compound
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0819287.4A GB0819287D0 (en) | 2008-10-22 | 2008-10-22 | Compounds |
| GB0819287.4 | 2008-10-22 | ||
| PCT/GB2009/002484 WO2010046628A1 (en) | 2008-10-22 | 2009-10-20 | Compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012506408A JP2012506408A (ja) | 2012-03-15 |
| JP2012506408A5 true JP2012506408A5 (enExample) | 2012-12-06 |
| JP5820272B2 JP5820272B2 (ja) | 2015-11-24 |
Family
ID=40097772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011532704A Expired - Fee Related JP5820272B2 (ja) | 2008-10-22 | 2009-10-20 | 化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US8927486B2 (enExample) |
| EP (2) | EP3446715A1 (enExample) |
| JP (1) | JP5820272B2 (enExample) |
| CN (2) | CN102143762B (enExample) |
| CA (1) | CA2741475A1 (enExample) |
| CY (1) | CY1121309T1 (enExample) |
| DK (1) | DK2349344T5 (enExample) |
| ES (1) | ES2714590T3 (enExample) |
| GB (1) | GB0819287D0 (enExample) |
| HR (1) | HRP20190437T8 (enExample) |
| HU (1) | HUE042688T2 (enExample) |
| LT (1) | LT2349344T (enExample) |
| PL (1) | PL2349344T3 (enExample) |
| PT (1) | PT2349344T (enExample) |
| SI (1) | SI2349344T1 (enExample) |
| SM (1) | SMT201900127T1 (enExample) |
| TR (1) | TR201902884T4 (enExample) |
| WO (1) | WO2010046628A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0707034D0 (en) | 2007-04-12 | 2007-05-23 | St Andrews The | Compounds |
| GB0819287D0 (en) | 2008-10-22 | 2008-11-26 | Univ Bradford | Compounds |
| JP6356684B2 (ja) | 2012-11-02 | 2018-07-11 | マレイ・アンド・プール・エンタープライゼズ・リミテッド | コルヒチン誘導体の投与による心血管イベントの処置または予防 |
| BR112015026418B1 (pt) | 2013-04-16 | 2022-10-04 | Murray And Poole Enterprises Limited | Formulação de liberação prolongada de colchicina e uso da referida formulação de liberação prolongada de colchicina |
| GB2516882A (en) * | 2013-08-02 | 2015-02-11 | Univ Bradford | Tumour-targeted theranostic |
| RU2715232C2 (ru) | 2013-09-25 | 2020-02-26 | Сайтомкс Терапьютикс, Инк. | Субстраты матриксной металлопротеиназы и другие расщипляемые фрагменты и способы их использования |
| ES3057033T3 (en) | 2014-01-31 | 2026-02-25 | Cytomx Therapeutics Inc | Matriptase and u-plasminogen activator substrates and other cleavable moieties and methods of use thereof |
| MA41374A (fr) | 2015-01-20 | 2017-11-28 | Cytomx Therapeutics Inc | Substrats clivables par métalloprotéase matricielle et clivables par sérine protéase et procédés d'utilisation de ceux-ci |
| GB2545169B (en) * | 2015-12-01 | 2019-10-09 | Ellipses Pharma Ltd | Taxane Prodrug Comprising A Membrane Type Matrix Metalloproteinase Cleavage Site |
| CA3120327A1 (en) | 2018-12-06 | 2020-06-11 | Cytomx Therapeutics, Inc. | Matrix metalloprotease-cleavable and serine or cysteine protease-cleavable substrates and methods of use thereof |
| CN115353534B (zh) * | 2021-12-31 | 2024-06-07 | 郑州大学第一附属医院 | 一种秋水仙碱衍生物及其制备和其应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US819287A (en) * | 1905-09-11 | 1906-05-01 | Caesar Klaus | Automatic brake. |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| EE200200522A (et) * | 2000-03-15 | 2004-04-15 | Bristol-Myers Squibb Pharma Company | Toimeainega konjugeerunud ensüüm-lõhustuv peptiid, seda sisaldav farmatseutiline kompositsioon ningühendi kasutamine kasvajavastase ravimina |
| GB0018240D0 (en) | 2000-07-25 | 2000-09-13 | Pharmacia & Upjohn Spa | Polymeric conjugates of antitumor agents |
| GB0105929D0 (en) | 2001-03-09 | 2001-04-25 | Btg Int Ltd | Physiologically activated prodrugs |
| DK1545613T3 (da) | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| US20050106100A1 (en) | 2003-09-03 | 2005-05-19 | Harris Thomas D. | Compounds containing matrix metalloproteinase substrates and methods of their use |
| GB0320691D0 (en) * | 2003-09-04 | 2003-10-01 | Smith & Nephew | Use of joint lining cells for articular cartilage repair |
| US8420603B2 (en) * | 2004-05-14 | 2013-04-16 | Abraxis Bioscience, Llc | SPARC and methods of use thereof |
| SG158919A1 (en) | 2005-01-24 | 2010-02-26 | Univ Texas | Constructs binding to phosphatidylserine and their use in disease treatment |
| WO2006090813A1 (ja) | 2005-02-25 | 2006-08-31 | National University Corporation Hokkaido University | 腫瘍組織で選択的に分解性を示す血中滞留性素子 |
| US7714016B2 (en) | 2005-04-08 | 2010-05-11 | Medarex, Inc. | Cytotoxic compounds and conjugates with cleavable substrates |
| GB0707034D0 (en) * | 2007-04-12 | 2007-05-23 | St Andrews The | Compounds |
| GB0819287D0 (en) | 2008-10-22 | 2008-11-26 | Univ Bradford | Compounds |
-
2008
- 2008-10-22 GB GBGB0819287.4A patent/GB0819287D0/en not_active Ceased
-
2009
- 2009-10-20 EP EP18194638.5A patent/EP3446715A1/en not_active Withdrawn
- 2009-10-20 CA CA2741475A patent/CA2741475A1/en not_active Abandoned
- 2009-10-20 WO PCT/GB2009/002484 patent/WO2010046628A1/en not_active Ceased
- 2009-10-20 CN CN200980141703.3A patent/CN102143762B/zh not_active Expired - Fee Related
- 2009-10-20 SM SM20190127T patent/SMT201900127T1/it unknown
- 2009-10-20 LT LTEP09760548.9T patent/LT2349344T/lt unknown
- 2009-10-20 EP EP09760548.9A patent/EP2349344B1/en active Active
- 2009-10-20 TR TR2019/02884T patent/TR201902884T4/tr unknown
- 2009-10-20 SI SI200931938T patent/SI2349344T1/sl unknown
- 2009-10-20 DK DK09760548.9T patent/DK2349344T5/en active
- 2009-10-20 CN CN201410401756.7A patent/CN104193802B/zh not_active Expired - Fee Related
- 2009-10-20 US US13/125,732 patent/US8927486B2/en not_active Expired - Fee Related
- 2009-10-20 PL PL09760548T patent/PL2349344T3/pl unknown
- 2009-10-20 ES ES09760548T patent/ES2714590T3/es active Active
- 2009-10-20 JP JP2011532704A patent/JP5820272B2/ja not_active Expired - Fee Related
- 2009-10-20 PT PT09760548T patent/PT2349344T/pt unknown
- 2009-10-20 HR HRP20190437TT patent/HRP20190437T8/hr unknown
- 2009-10-20 HU HUE09760548A patent/HUE042688T2/hu unknown
-
2014
- 2014-11-25 US US14/553,803 patent/US20150196658A1/en not_active Abandoned
-
2016
- 2016-10-19 US US15/297,649 patent/US9937267B2/en active Active
-
2018
- 2018-03-01 US US15/909,475 patent/US10912839B2/en not_active Expired - Fee Related
-
2019
- 2019-02-27 CY CY20191100241T patent/CY1121309T1/el unknown
-
2020
- 2020-06-19 US US16/946,391 patent/US20200316212A1/en not_active Abandoned
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