JP2010502734A5 - - Google Patents

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JP2010502734A5
JP2010502734A5 JP2009527565A JP2009527565A JP2010502734A5 JP 2010502734 A5 JP2010502734 A5 JP 2010502734A5 JP 2009527565 A JP2009527565 A JP 2009527565A JP 2009527565 A JP2009527565 A JP 2009527565A JP 2010502734 A5 JP2010502734 A5 JP 2010502734A5
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therapeutic composition
component comprises
elp component
composition according
elp
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JP2009527565A
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JP5395664B2 (ja
JP2010502734A (ja
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Priority claimed from PCT/US2007/077767 external-priority patent/WO2008030968A2/en
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JP2009527565A 2006-09-06 2007-09-06 融合ペプチド治療用組成物 Active JP5395664B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84246406P 2006-09-06 2006-09-06
US60/842,464 2006-09-06
PCT/US2007/077767 WO2008030968A2 (en) 2006-09-06 2007-09-06 Fusion peptide therapeutic compositions

Related Child Applications (1)

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JP2013217181A Division JP5802250B2 (ja) 2006-09-06 2013-10-18 融合ペプチド治療用組成物

Publications (3)

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JP2010502734A JP2010502734A (ja) 2010-01-28
JP2010502734A5 true JP2010502734A5 (enExample) 2010-10-14
JP5395664B2 JP5395664B2 (ja) 2014-01-22

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JP2009527565A Active JP5395664B2 (ja) 2006-09-06 2007-09-06 融合ペプチド治療用組成物
JP2013217181A Active JP5802250B2 (ja) 2006-09-06 2013-10-18 融合ペプチド治療用組成物
JP2015168457A Pending JP2016026167A (ja) 2006-09-06 2015-08-28 融合ペプチド治療用組成物

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JP2013217181A Active JP5802250B2 (ja) 2006-09-06 2013-10-18 融合ペプチド治療用組成物
JP2015168457A Pending JP2016026167A (ja) 2006-09-06 2015-08-28 融合ペプチド治療用組成物

Country Status (9)

Country Link
US (3) US20110039776A1 (enExample)
EP (1) EP2059606A4 (enExample)
JP (3) JP5395664B2 (enExample)
CN (2) CN101578373A (enExample)
AU (1) AU2007292295B2 (enExample)
CA (1) CA2663047A1 (enExample)
IL (2) IL197442A (enExample)
MX (1) MX2009002547A (enExample)
WO (1) WO2008030968A2 (enExample)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080082597A (ko) * 2005-07-28 2008-09-11 글로벌 리서치 테크놀로지스, 엘엘씨 공기로부터 이산화탄소의 제거
US8334257B2 (en) 2005-12-20 2012-12-18 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US7709227B2 (en) 2006-01-04 2010-05-04 Phasebio Pharmaceuticals, Inc. Multimeric ELP fusion constructs
EP2004813B1 (en) 2006-04-03 2015-06-03 Promega Corporation Permuted and nonpermuted luciferase biosensors binding cyclic nucleotides
JP6110591B2 (ja) 2008-05-19 2017-04-05 プロメガ コーポレイションPromega Corporation cAMPのためのルシフェラーゼバイオセンサー
EP3412300A1 (en) * 2008-06-27 2018-12-12 Duke University Therapeutic agents comprising elastin-like peptides
EP2307540B1 (en) 2008-07-07 2017-04-19 Oxford Nanopore Technologies Limited Enzyme-pore constructs
JP2011527191A (ja) 2008-07-07 2011-10-27 オックスフォード ナノポア テクノロジーズ リミテッド 塩基検出細孔
GB0820927D0 (en) 2008-11-14 2008-12-24 Isis Innovation Method
CN101418290A (zh) * 2008-12-02 2009-04-29 中山大学 一种高效的elp融合蛋白酶及其制备和应用
WO2010085768A1 (en) 2009-01-26 2010-07-29 Nanoink,Inc. Large area, homogeneous array fabbrication including leveling with use of bright spots
WO2010086622A1 (en) 2009-01-30 2010-08-05 Oxford Nanopore Technologies Limited Adaptors for nucleic acid constructs in transmembrane sequencing
BRPI1007215A2 (pt) * 2009-01-30 2017-08-29 Oxford Nanopore Tech Ltd Método de acoplamento covalente de duas ou mais porções, primeira e segunda porções, primeiro porção acoplada a uma segunda porção, par de primeiro e segundo ligantes, e, uso de um par de ligantes.
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
US20100316623A1 (en) * 2009-04-23 2010-12-16 Andrew Turner Phenylalanine hydroxylase fusion protein and methods for treating phenylketonuria
WO2011020091A1 (en) 2009-08-14 2011-02-17 Phasebio Pharmaceuticals, Inc. Modified vasoactive intestinal peptides
US8940868B2 (en) * 2009-10-08 2015-01-27 The General Hospital Corporation Elastin based growth factor delivery platform for wound healing and regeneration
US9035028B2 (en) * 2010-03-10 2015-05-19 Emory University Temperature sensitive conjugate compositions
EP2990479B1 (en) 2010-05-11 2019-03-27 Promega Corporation Mutant protease biosensors with enhanced detection characteristics
US9290794B2 (en) 2010-05-11 2016-03-22 Promega Corporation Mutant protease biosensors with enhanced detection characteristics
CN101955960B (zh) * 2010-08-03 2012-05-23 中山大学 一种利用类弹性蛋白标签纯化重组乳糖酶的方法
KR101939420B1 (ko) 2011-02-11 2019-01-16 옥스포드 나노포어 테크놀로지즈 리미티드 돌연변이체 세공
US20120213781A1 (en) 2011-02-11 2012-08-23 Zyngenia, Inc. Monovalent and Multivalent Multispecific Complexes and Uses Thereof
EP2717902B1 (en) 2011-06-06 2018-01-24 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
CN102241747A (zh) * 2011-06-17 2011-11-16 李立文 类人弹性蛋白及其生产方法
BR112014001699A2 (pt) 2011-07-25 2017-06-13 Oxford Nanopore Tech Ltd método para sequenciar de um polinucleotídeo alvo de filamento duplo, kit, métodos para preparar um polinucleotídeo alvo de filamento duplo para sequenciamento e para sequenciar um polinucleotídeo alvo de filamento duplo, e, aparelho
US9102763B2 (en) 2011-07-26 2015-08-11 University Of Southern California Controlled release of ocular biopharmaceuticals using bioresponsive protein polymers
CN104023784B (zh) * 2011-08-24 2018-05-25 费斯生物制药公司 供持续释放的活性剂制剂
WO2013120022A2 (en) * 2012-02-08 2013-08-15 Seneb Biosciences, Inc. Treatment of hypoglycemia
US20130210747A1 (en) 2012-02-13 2013-08-15 University Of Southern California Methods and Therapeutics Comprising Ligand-Targeted ELPs
JP6157877B2 (ja) * 2012-02-28 2017-07-05 三洋化成工業株式会社 組織再生用ゲル、組織再生用タンパク質溶液及び組織再生用ゲルの製造方法
CA2869546C (en) 2012-04-10 2020-07-21 Oxford Nanopore Technologies Limited Mutant lysenin pores
EP2875154B1 (en) 2012-07-19 2017-08-23 Oxford Nanopore Technologies Limited SSB method for characterising a nucleic acid
WO2014026054A2 (en) 2012-08-10 2014-02-13 University Of Southern California CD20 scFv-ELPs METHODS AND THERAPEUTICS
WO2014028776A1 (en) * 2012-08-15 2014-02-20 Zyngenia, Inc. Monovalent and multivalent multispecific complexes and uses thereof
JP2016505627A (ja) * 2013-01-15 2016-02-25 フェーズバイオ ファーマシューティカルズ,インコーポレイテッド 治療剤、組成物、および血糖コントロールのための方法
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
AU2014224432B2 (en) 2013-03-08 2019-10-24 Oxford Nanopore Technologies Limited Enzyme stalling method
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
EP3052125B1 (en) * 2013-10-01 2020-09-30 University of Mississippi Medical Center Elastin-like polypeptide coupled to therapeutic agent for delivery during pregnancy
WO2015120091A1 (en) * 2014-02-04 2015-08-13 Duke University Systems and devices for protease detection based on engineered polymers and biopolymers and methods of use
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
ES2879804T3 (es) 2014-04-21 2021-11-23 D&D Pharmatech Inc Agonistas del receptor de TRAIL para el tratamiento de enfermedades fibróticas
EP3137490B1 (en) 2014-05-02 2021-01-27 Oxford Nanopore Technologies Limited Mutant pores
US11052132B2 (en) 2014-05-08 2021-07-06 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating cystic fibrosis
WO2016034591A2 (en) 2014-09-01 2016-03-10 Vib Vzw Mutant pores
EP3204511B1 (en) 2014-10-07 2021-07-28 Oxford Nanopore Technologies Limited Mutant pores
GB201418159D0 (en) 2014-10-14 2014-11-26 Oxford Nanopore Tech Ltd Method
AU2015349743B2 (en) 2014-11-21 2021-06-10 Immunoforge Co., Ltd. ELP fusion proteins for controlled and sustained release
CA2970478A1 (en) 2014-12-10 2016-06-16 S-Aima Holding Company, Llc Generation of hemoglobin-based oxygen carriers using elastin-like polypeptides
CA2976038A1 (en) 2015-02-09 2016-08-18 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating muscle disease and disorders
US10639371B2 (en) * 2015-07-29 2020-05-05 University Of Delaware Thermoresponsive bioconjugates and their controlled delivery of cargo
CN106632682A (zh) * 2015-08-04 2017-05-10 清华大学 融合蛋白ifn-elp及其应用
CA2994279A1 (en) 2015-08-04 2017-02-09 Duke University Genetically encoded intrinsically disordered stealth polymers for delivery and methods of using same
KR101759122B1 (ko) 2015-08-07 2017-07-18 계명대학교 산학협력단 오렉신 a를 함유하는 당뇨병 치료용 약학 조성물
JP6797203B2 (ja) 2015-12-17 2020-12-09 ザ・ジョンズ・ホプキンス・ユニバーシティー デスレセプターアゴニストによる全身性硬化症の改善
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
US11059870B2 (en) 2016-03-14 2021-07-13 Industry-University Cooperation Foundation Hanyang University Erica Campus Polypeptides with phase transition, triblock polypeptides of the polypeptide-calmodulin-polypeptide with multi-stimuli responsiveness, hydrogel of the triblock polypeptides, and its uses
KR102028931B1 (ko) * 2016-03-24 2019-10-08 한양대학교 에리카산학협력단 지능형 약물 전달을 위한 다중 자극 반응성을 지닌 칼모듈린-엘라스틴 이중 블럭 폴리펩타이드의 동적 나노 전달체 및 제조방법
KR102508650B1 (ko) 2016-04-07 2023-03-13 더 존스 홉킨스 유니버시티 사멸 수용체 작용제로써 췌장암 및 통증을 치료하기 위한 조성물 및 방법
WO2017192449A1 (en) * 2016-05-06 2017-11-09 Phasebio Pharmaceuticals, Inc. Elp fusion proteins for controlled and sustained release
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
WO2017210476A1 (en) 2016-06-01 2017-12-07 Duke University Nonfouling biosensors
CN107459580A (zh) * 2016-06-06 2017-12-12 易金阳 一种利用酵母菌表达含有穿膜肽的寡肽‑1(egf)创新制备工艺
WO2018053201A1 (en) 2016-09-14 2018-03-22 Duke University Triblock polypeptide-based nanoparticles for the delivery of hydrophilic drugs
JP2020500150A (ja) 2016-09-23 2020-01-09 デューク ユニバーシティ 下限臨界溶液温度挙動を有する非反復かつ非構造的ポリペプチド
CN106519040B (zh) * 2016-11-02 2020-03-27 南京大学 一种含肿瘤坏死因子相关凋亡诱导配体的融合蛋白和其制备方法及由该蛋白自组装的纳米粒
US11648200B2 (en) 2017-01-12 2023-05-16 Duke University Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
WO2018213320A1 (en) 2017-05-15 2018-11-22 Duke University Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
KR101955366B1 (ko) * 2017-06-02 2019-03-07 인제대학교 산학협력단 인터페론 베타-엘라스틴 재조합 단백질 및 이의 생산방법
US11680083B2 (en) 2017-06-30 2023-06-20 Duke University Order and disorder as a design principle for stimuli-responsive biopolymer networks
JP7074995B2 (ja) * 2017-10-13 2022-05-25 林兼産業株式会社 線維芽細胞増殖促進剤及び線維芽細胞におけるエラスチン産生促進剤
WO2019147954A1 (en) 2018-01-26 2019-08-01 Duke University Albumin binding peptide-drug (aibiped) conjugates and methods of making and using same
CN108531492A (zh) * 2018-04-23 2018-09-14 内蒙古农业大学 利用类弹性蛋白elp构建活性绵羊β-防御素sbd-1体外表达的方法
US12257308B2 (en) 2018-04-30 2025-03-25 Duke University Stimuli-responsive PEG-like polymer-based drug delivery platform
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
US11649275B2 (en) 2018-08-02 2023-05-16 Duke University Dual agonist fusion proteins
EP3837276A4 (en) 2018-08-16 2022-05-18 Isolere Bio, Inc. Genetically encoded polypeptide for affinity capture and purification of biologics
US11512314B2 (en) 2019-07-12 2022-11-29 Duke University Amphiphilic polynucleotides
WO2021030196A1 (en) * 2019-08-09 2021-02-18 Phasebio Pharmaceuticals, Inc. Elp fusion proteins comprising parathyroid hormone for controlled and sustained release
US20230099707A1 (en) * 2020-02-19 2023-03-30 Isolere Bio, Inc. Protein-based purification matrices and methods of using the same
WO2021202546A1 (en) 2020-03-31 2021-10-07 Cyclerion Therapeutics, Inc. Early drug interventions to reduce covid-19 related respiratory distress, need for ventilator assistance and death
US11767353B2 (en) 2020-06-05 2023-09-26 Theraly Fibrosis, Inc. Trail compositions with reduced immunogenicity
KR102687389B1 (ko) * 2020-08-25 2024-07-25 한양대학교 에리카산학협력단 자극 반응성 및 표면 부착성을 가진 점착성 엘라스틴 및 서커린 기반 다중 블록 코폴리펩타이드, 그의 자가조립 구조체 및 주사형 하이드로겔의 생접착제 응용
KR20230125179A (ko) 2020-12-23 2023-08-29 재즈 파마슈티칼즈 아일랜드 리미티드 전하-차폐 융합 단백질의 정제 방법
JP2024509742A (ja) * 2021-02-19 2024-03-05 ドナルドソン カンパニー,インコーポレイティド 相挙動を有するタンパク質を含む融合タンパク質
EP4530300A4 (en) * 2022-05-23 2026-03-25 Univ Fudan Clover Factor 2 Fusion Protein/Interferon Alpha2 and its Use in the Prevention and Treatment of Viral Infectious Diseases
CN115724915B (zh) * 2022-08-17 2025-08-12 上普博源(北京)生物科技有限公司 类弹性蛋白多肽粘合剂及其制备方法与应用
CN117777303A (zh) * 2022-09-27 2024-03-29 北京大学 一种高亲和力pd1蛋白偶联物及其应用
JP2025541413A (ja) * 2022-12-27 2025-12-18 ネクスセラ カンパニー リミテッド エラスチン類似ポリペプチド基盤の組換えタンパク質の作製及びその動物細胞発現プラットフォーム
WO2025076213A1 (en) * 2023-10-04 2025-04-10 The Board Of Trustees Of The Leland Stanford Junior University Isothermally phase-separable elastin-like polypeptides, compositions, and methods of use thereof
WO2025100511A1 (ja) * 2023-11-10 2025-05-15 地方独立行政法人神奈川県立産業技術総合研究所 融合ペプチド

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100627590B1 (ko) * 1998-01-30 2006-09-25 다이이치 아스비오파마 가부시키가이샤 보조 펩타이드를 사용하는 펩타이드의 제조방법
US6852834B2 (en) * 2000-03-20 2005-02-08 Ashutosh Chilkoti Fusion peptides isolatable by phase transition
US20050255554A1 (en) * 2000-03-20 2005-11-17 Ashutosh Chilkoti Fusion peptides isolatable by phase transition
JP2003530838A (ja) * 2000-04-12 2003-10-21 ヒューマン ゲノム サイエンシズ インコーポレイテッド アルブミン融合タンパク質
UA93662C2 (uk) * 2000-12-07 2011-03-10 Эли Лилли Энд Компани Гетерологічний пептидильований глюкагон-подібний білок та його застосування для виготовлення лікарського засобу для лікування пацієнтів, що страждають на ожиріння або інсулінонезалежний цукровий діабет
US20030098869A1 (en) * 2001-11-09 2003-05-29 Arnold Glenn Christopher Real time interactive video system
EP1545595B1 (en) * 2002-08-30 2010-07-07 Biorexis Pharmaceutical Corporation Modified transferrin fusion proteins comprising duplicate transferrin amino or carboxy terminal domains
EA008831B1 (ru) * 2003-06-12 2007-08-31 Эли Лилли Энд Компани Слитые белки аналогов glp-1
JP4149867B2 (ja) * 2003-07-28 2008-09-17 キヤノンファインテック株式会社 プリンタ、その制御方法
US7019845B1 (en) * 2004-10-06 2006-03-28 Rudolph Technologies, Inc. Measuring elastic moduli of dielectric thin films using an optical metrology system
WO2006110292A2 (en) * 2005-03-25 2006-10-19 The Regents Of The University Of California Temperature-triggered immobilization and purification of antibodies

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