JP2012528857A5 - - Google Patents
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- Publication number
- JP2012528857A5 JP2012528857A5 JP2012513928A JP2012513928A JP2012528857A5 JP 2012528857 A5 JP2012528857 A5 JP 2012528857A5 JP 2012513928 A JP2012513928 A JP 2012513928A JP 2012513928 A JP2012513928 A JP 2012513928A JP 2012528857 A5 JP2012528857 A5 JP 2012528857A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- lipid
- peg
- peg chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21762709P | 2009-06-02 | 2009-06-02 | |
| US61/217,627 | 2009-06-02 | ||
| US28406509P | 2009-12-12 | 2009-12-12 | |
| US61/284,065 | 2009-12-12 | ||
| PCT/US2010/001590 WO2010141069A2 (en) | 2009-06-02 | 2010-06-01 | Pure peg-lipid conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012528857A JP2012528857A (ja) | 2012-11-15 |
| JP2012528857A5 true JP2012528857A5 (enExample) | 2013-08-15 |
Family
ID=43298359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012513928A Pending JP2012528857A (ja) | 2009-06-02 | 2010-06-01 | 純粋ｐｅｇ−脂質コンジュゲート |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20110040113A1 (enExample) |
| EP (1) | EP2437756A2 (enExample) |
| JP (1) | JP2012528857A (enExample) |
| KR (1) | KR20120039564A (enExample) |
| CN (1) | CN102665685A (enExample) |
| AP (1) | AP2012006053A0 (enExample) |
| AU (1) | AU2010257181A1 (enExample) |
| BR (1) | BRPI1010175A2 (enExample) |
| CA (1) | CA2763819A1 (enExample) |
| CL (1) | CL2011003049A1 (enExample) |
| CO (1) | CO6511284A2 (enExample) |
| IL (1) | IL216719A0 (enExample) |
| MX (1) | MX2011012823A (enExample) |
| WO (1) | WO2010141069A2 (enExample) |
| ZA (1) | ZA201109366B (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9393315B2 (en) | 2011-06-08 | 2016-07-19 | Nitto Denko Corporation | Compounds for targeting drug delivery and enhancing siRNA activity |
| US20120202890A1 (en) | 2011-02-08 | 2012-08-09 | Nian Wu | Polymer-carbohydrate-lipid conjugates |
| WO2012122144A1 (en) * | 2011-03-07 | 2012-09-13 | Wu Nian | Highly monodisperse branched peg-lipid conjugates |
| US10196637B2 (en) | 2011-06-08 | 2019-02-05 | Nitto Denko Corporation | Retinoid-lipid drug carrier |
| US8883177B2 (en) | 2011-06-28 | 2014-11-11 | Nian Wu | Pharmaceutical compositions for parenteral administration |
| JP6051758B2 (ja) * | 2011-10-17 | 2016-12-27 | 日油株式会社 | ジアシルグリセロールと結合した分岐型ポリエチレングリコール、その製造方法およびポリエチレングリコール修飾リポソーム |
| PL2887958T3 (pl) | 2012-08-21 | 2021-11-22 | Opko Pharmaceuticals, Llc | Formulacje liposomowe |
| US11458199B2 (en) | 2012-08-21 | 2022-10-04 | Opko Pharmaceuticals, Llc | Liposome formulations |
| PL2887923T3 (pl) | 2012-08-24 | 2023-08-14 | Sun Pharmaceutical Industries Limited | Preparat okulistyczny polioksylipidu lub polioksylowego kwasu tłuszczowego i leczenie chorób oczu |
| WO2015021044A1 (en) * | 2013-08-05 | 2015-02-12 | University Of Rochester | Compositions and methods for stimuli-responsive release of a therapeutic agent |
| CN113274506A (zh) * | 2013-12-05 | 2021-08-20 | 念·吴 | 聚合物-碳水化合物的缀合物的药物转递技术 |
| JP6461973B2 (ja) * | 2013-12-20 | 2019-01-30 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ２以上の疎水性ドメインおよびｐｅｇ部分を含む親水性ドメインを含む化合物の、細胞の安定化のための使用 |
| ES2708360T3 (es) * | 2013-12-20 | 2019-04-09 | Hoffmann La Roche | Compuestos que comprenden uno o más dominios hidrófobos y un dominio hidrófilo que comprende restos de PEG, útiles para unir células |
| WO2015091948A1 (en) | 2013-12-20 | 2015-06-25 | Roche Diagnostics Gmbh | Method of immobilizing a cell on a support using compounds comprising a polyethylene glycol moiety |
| AU2015360794B2 (en) | 2014-12-08 | 2021-07-08 | The Board Of Regents Of The University Of Texas System | Lipocationic polymers and uses thereof |
| US10064954B2 (en) * | 2015-06-23 | 2018-09-04 | Nian Wu | Polymer-cyclodextrin-lipid conjugates |
| EP3349802B1 (en) | 2015-09-14 | 2021-08-04 | The Board of Regents of the University of Texas System | Lipocationic dendrimers and uses thereof |
| JP2018532809A (ja) | 2015-11-10 | 2018-11-08 | サン ファーマ グローバル エフジーイー | 局所製剤およびその使用 |
| MD3386484T2 (ro) | 2015-12-10 | 2022-11-30 | Modernatx Inc | Compoziții și metode de livrare a unor agenți terapeutici |
| CN106905120B (zh) * | 2015-12-21 | 2020-04-28 | 北京键凯科技股份有限公司 | Y型多缩乙二醇衍生物及其制备方法 |
| DK3423076T3 (da) | 2016-02-29 | 2024-07-08 | Sun Pharmaceutical Ind Ltd | Topisk cyclosporinholdige formuleringer og anvendelser deraf |
| CN109414451B (zh) | 2016-05-16 | 2022-08-12 | 德克萨斯大学系统董事会 | 用于作为纳米粒递送tRNA的组合物及其使用方法 |
| US10562849B2 (en) | 2016-05-16 | 2020-02-18 | The Board Of Regents Of The University Of Texas System | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids |
| KR102546103B1 (ko) * | 2018-03-20 | 2023-06-21 | 니치유 가부시키가이샤 | 분기형 단분산 폴리에틸렌 글리콜, 중간체 및 그 제조 방법 |
| CN111936549B (zh) * | 2018-03-29 | 2023-03-10 | 日油株式会社 | 包含三苯甲基的单分散聚乙二醇的纯化方法 |
| WO2019191597A1 (en) * | 2018-03-30 | 2019-10-03 | The Board Of Regents Of The University Of Oklahoma | Very long chain saturated fatty acid compounds, compositions containing same, and methods of use |
| US12357580B2 (en) | 2018-06-19 | 2025-07-15 | The Board Of Regents Of The University Of Texas System | Lipid nanoparticle compositions for delivery of mRNA and long nucleic acids |
| EP3846857A4 (en) | 2018-09-04 | 2022-10-12 | The Board Of Regents Of The University Of Texas System | COMPOSITIONS AND METHODS FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACIDS |
| GB2592505B (en) | 2018-09-04 | 2023-05-03 | Univ Texas | Compositions and methods for organ specific delivery of nucleic acids |
| EP4509118A3 (en) * | 2018-09-19 | 2025-05-14 | ModernaTX, Inc. | High-purity peg lipids and uses thereof |
| JP6805385B1 (ja) * | 2020-08-31 | 2020-12-23 | ジェイ−ネットワーク，インコーポレイテッド | 表皮内の保湿関連物質の発現増強剤 |
| IL320367A (en) | 2020-10-09 | 2025-06-01 | Univ Texas | Prefusion-stabilized hmpv f proteins |
| JP6860739B1 (ja) * | 2020-11-20 | 2021-04-21 | ジェイ−ネットワーク，インコーポレイテッド | 表皮内の抗酸化物質の発現増強剤 |
| CN114685778B (zh) * | 2020-12-30 | 2023-10-17 | 苏州艾博生物科技有限公司 | 长循环阳离子脂质体的合成方法 |
| US20240123076A1 (en) | 2021-02-08 | 2024-04-18 | The Board Of Regents Of The University Of Texas System | Unsaturated dendrimers compositions, related formulations, and methods of use thereof |
| AU2022242828A1 (en) | 2021-03-23 | 2023-10-12 | Recode Therapeutics, Inc. | Polynucleotide compositions, related formulations, and methods of use thereof |
| CA3215509A1 (en) | 2021-04-22 | 2022-10-27 | Daniel J. Siegwart | All-in-one dendrimer-based lipid nanoparticles enable precise hdr-mediated gene editing in vivo |
| CN114276535B (zh) | 2021-06-30 | 2022-06-21 | 天津键凯科技有限公司 | 聚乙二醇脂质及其应用 |
| CN113461929B (zh) * | 2021-07-13 | 2023-04-21 | 浙江倍合德制药有限公司 | 一种tpgs系列产品的精制提纯方法 |
| CN116410460B (zh) * | 2021-12-29 | 2025-08-05 | 辅必成（上海）医药科技有限公司 | 一种1,2-二肉豆蔻酰-rac-甘油-3-甲氧基聚乙二醇2000的制备方法 |
| CN114507342B (zh) * | 2022-03-18 | 2024-03-19 | 江苏东南纳米材料有限公司 | 一种1,2-二肉豆蔻酰-rac-甘油-3-甲氧基聚乙二醇及其中间体的制备方法 |
| EP4504265A1 (en) * | 2022-04-05 | 2025-02-12 | Capstan Therapeutics, Inc. | Peg-lipids and lipid nanoparticles |
| CN114524943B (zh) * | 2022-04-22 | 2022-09-16 | 天津凯莱英制药有限公司 | 聚乙二醇-甘油衍生物及其中间体各自的制备方法 |
| CN117003807A (zh) * | 2022-04-28 | 2023-11-07 | 北京科兴中维生物技术有限公司 | 一种结构脂质化合物及其制备方法和用途 |
| JP2025539101A (ja) * | 2022-11-15 | 2025-12-03 | エボニック オペレーションズ ゲーエムベーハー | ポリオキシアルキレンがｃ１～ｃ３－アルキルオキシメチル側鎖を有するポリ（エチレンオキシド）である、ポリオキシアルキレン－１，２－ジミリストイル－グリセロール化合物 |
| CN120693181A (zh) | 2022-12-08 | 2025-09-23 | 瑞科德治疗公司 | 脂质纳米颗粒组合物及其用途 |
| IL321992A (en) | 2023-01-09 | 2025-09-01 | Univ Texas | Human parainfluenza virus 3f proteins stabilized before transfusion |
| CN116178733B (zh) * | 2023-03-03 | 2023-08-01 | 浙江博美生物技术有限公司 | 一种基于三官能团氨基酸的支化单分散peg衍生物、制备方法和应用 |
| US12364773B2 (en) | 2023-12-01 | 2025-07-22 | Recode Therapeutics, Inc. | Lipid nanoparticle compositions and uses thereof |
| WO2025137646A1 (en) | 2023-12-22 | 2025-06-26 | Recode Therapeutics, Inc. | Gene editing methods and compositions for treating cystic fibrosis |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5827533A (en) * | 1997-02-06 | 1998-10-27 | Duke University | Liposomes containing active agents aggregated with lipid surfactants |
| US7141552B2 (en) * | 2000-01-10 | 2006-11-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of diseases |
| EP1664316B1 (en) * | 2003-09-15 | 2012-08-29 | Protiva Biotherapeutics Inc. | Polyethyleneglycol-modified lipid compounds and uses thereof |
| US20060051405A1 (en) * | 2004-07-19 | 2006-03-09 | Protiva Biotherapeutics, Inc. | Compositions for the delivery of therapeutic agents and uses thereof |
| CA2629330C (en) * | 2004-11-12 | 2018-05-22 | Cambridge University Technical Services Ltd. | Methods and means related to cancer stem cells |
| AU2008321174A1 (en) * | 2007-11-14 | 2009-05-22 | The Regents Of The University Of California | Sterol-modified amphiphilic lipids |
-
2010
- 2010-06-01 EP EP10783699A patent/EP2437756A2/en not_active Withdrawn
- 2010-06-01 JP JP2012513928A patent/JP2012528857A/ja active Pending
- 2010-06-01 US US12/802,197 patent/US20110040113A1/en not_active Abandoned
- 2010-06-01 BR BRPI1010175A patent/BRPI1010175A2/pt not_active Application Discontinuation
- 2010-06-01 KR KR1020117031713A patent/KR20120039564A/ko not_active Withdrawn
- 2010-06-01 CA CA2763819A patent/CA2763819A1/en not_active Abandoned
- 2010-06-01 AP AP2012006053A patent/AP2012006053A0/xx unknown
- 2010-06-01 CN CN2010800303714A patent/CN102665685A/zh active Pending
- 2010-06-01 WO PCT/US2010/001590 patent/WO2010141069A2/en not_active Ceased
- 2010-06-01 AU AU2010257181A patent/AU2010257181A1/en not_active Abandoned
- 2010-06-01 MX MX2011012823A patent/MX2011012823A/es not_active Application Discontinuation
-
2011
- 2011-12-01 IL IL216719A patent/IL216719A0/en unknown
- 2011-12-02 CL CL2011003049A patent/CL2011003049A1/es unknown
- 2011-12-20 ZA ZA2011/09366A patent/ZA201109366B/en unknown
- 2011-12-30 CO CO11181678A patent/CO6511284A2/es not_active Application Discontinuation
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