JP2012516894A5 - - Google Patents
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- Publication number
- JP2012516894A5 JP2012516894A5 JP2011549242A JP2011549242A JP2012516894A5 JP 2012516894 A5 JP2012516894 A5 JP 2012516894A5 JP 2011549242 A JP2011549242 A JP 2011549242A JP 2011549242 A JP2011549242 A JP 2011549242A JP 2012516894 A5 JP2012516894 A5 JP 2012516894A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- methyl
- somechi
- pyridin
- fluorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- -1 pyridin-yl Chemical group 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14940209P | 2009-02-03 | 2009-02-03 | |
| US61/149,402 | 2009-02-03 | ||
| PCT/US2010/023122 WO2010091131A1 (en) | 2009-02-03 | 2010-02-03 | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012516894A JP2012516894A (ja) | 2012-07-26 |
| JP2012516894A5 true JP2012516894A5 (https=) | 2013-03-07 |
| JP5584705B2 JP5584705B2 (ja) | 2014-09-03 |
Family
ID=42289775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011549242A Active JP5584705B2 (ja) | 2009-02-03 | 2010-02-03 | Ｒ）−３−（４−（２−（２−メチルテトラゾール−５−イル）ピリジン−５−イル）−３−フルオロフェニル）−５−ヒドロキシメチルオキサゾリジン−２−オンリン酸二水素の結晶形 |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US8426389B2 (https=) |
| EP (1) | EP2393808B1 (https=) |
| JP (1) | JP5584705B2 (https=) |
| KR (3) | KR101918678B1 (https=) |
| CN (2) | CN107082790A (https=) |
| AP (1) | AP2987A (https=) |
| AU (1) | AU2010210627B2 (https=) |
| BR (1) | BRPI1008829A2 (https=) |
| CA (1) | CA2751392C (https=) |
| CL (1) | CL2011001855A1 (https=) |
| CO (1) | CO6620071A2 (https=) |
| CR (1) | CR20110464A (https=) |
| CU (1) | CU24089B1 (https=) |
| DO (1) | DOP2011000251A (https=) |
| EC (1) | ECSP11011285A (https=) |
| ES (1) | ES2734724T3 (https=) |
| IL (1) | IL214401B (https=) |
| MA (1) | MA33092B1 (https=) |
| MX (3) | MX2011008093A (https=) |
| MY (1) | MY156354A (https=) |
| NZ (3) | NZ620458A (https=) |
| PE (1) | PE20120585A1 (https=) |
| PH (1) | PH12014500092B1 (https=) |
| RU (2) | RU2655928C1 (https=) |
| SG (2) | SG173497A1 (https=) |
| TN (1) | TN2011000381A1 (https=) |
| UA (1) | UA114068C2 (https=) |
| WO (1) | WO2010091131A1 (https=) |
| ZA (2) | ZA201106412B (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| RU2659792C1 (ru) | 2008-10-10 | 2018-07-04 | Мерк Шарп Энд Домэ Корп. | Оксазолидиноны и способ их очистки |
| MY156354A (en) | 2009-02-03 | 2016-02-15 | Merck Sharp & Dohme | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
| US8580767B2 (en) | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
| US8461188B2 (en) | 2011-10-20 | 2013-06-11 | Trius Therapeutics, Inc. | Therapeutic combination of daptomycin and protein synthesis inhibitor antibiotic, and methods of use |
| WO2015054246A1 (en) * | 2013-10-07 | 2015-04-16 | Trius Therapeutics, Inc. | Methods of treating subjects with renal impairment using tedizolid |
| US10189870B2 (en) | 2014-04-18 | 2019-01-29 | Hangzhou Pushai Pharmaeutical Technology Co., Ltd. | Crystalline form of oxazolidinone antibiotics and preparation method, composition and use thereof |
| WO2016009401A2 (en) * | 2014-07-18 | 2016-01-21 | Dr. Reddy's Laboratories Limited | Preparation of tedizolid phosphate |
| CN104327119A (zh) * | 2014-10-17 | 2015-02-04 | 苏州明锐医药科技有限公司 | 磷酸泰地唑胺的制备方法 |
| WO2016063246A1 (en) * | 2014-10-22 | 2016-04-28 | Sun Pharmaceutical Industries Limited | Crystalline form r of tedizolid phosphate |
| WO2016088100A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
| WO2016088102A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
| WO2016088101A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
| CZ306245B6 (cs) * | 2014-12-11 | 2016-10-26 | Univerzita Karlova v Praze Farmaceutická fakulta v Hradci Králové | Substituovaný fenyltetrazol, jeho použití a farmaceutický přípravek ho obsahující |
| CN104558034A (zh) * | 2015-01-21 | 2015-04-29 | 齐鲁制药有限公司 | 磷酸特地唑胺二钠盐的新晶型及其制备方法 |
| CN105837634B (zh) * | 2015-01-30 | 2020-09-04 | 上海创诺制药有限公司 | 一种泰地唑胺磷酸酯结晶体及其制备方法 |
| CN104592218B (zh) * | 2015-02-13 | 2015-11-04 | 江苏欧信医药化工有限公司 | 一种泰地唑胺的合成方法 |
| CN106146485B (zh) * | 2015-04-01 | 2021-04-30 | 上海迪赛诺化学制药有限公司 | 一种制备泰地唑胺的方法及其得到的泰地唑胺结晶体 |
| CN106146558A (zh) * | 2015-04-10 | 2016-11-23 | 博瑞生物医药（苏州）股份有限公司 | 新的噁唑烷酮类化合物及其制备方法 |
| CN106317114B (zh) * | 2015-07-02 | 2018-11-20 | 南京优科制药有限公司 | 一种磷酸特地唑胺的制备方法 |
| CN105085570B (zh) * | 2015-09-12 | 2017-11-28 | 山东罗欣药业集团股份有限公司 | 一种磷酸特地唑胺化合物及其制备方法 |
| CN105287407B (zh) * | 2015-11-24 | 2018-09-21 | 南京正大天晴制药有限公司 | 一种注射用磷酸特地唑胺 |
| CN107121503B (zh) * | 2017-03-14 | 2020-04-28 | 南京优科制药有限公司 | 一种磷酸特地唑胺及其有关物质的分析方法 |
| CN108948079A (zh) * | 2017-05-17 | 2018-12-07 | 上海奥博生物医药技术有限公司 | 一种特地唑胺二铵盐及晶型与其制备方法 |
| US11452719B2 (en) | 2017-12-13 | 2022-09-27 | Merck Sharp & Dohme Llc | Pharmaceutical compositions of tedizolid phosphate |
| WO2020021468A1 (en) | 2018-07-25 | 2020-01-30 | Cadila Healthcare Limited | Substituted oxazolidinones for the treatment of mammalian infections |
| CA3183397A1 (en) | 2020-06-18 | 2021-12-23 | Daryl C. Drummond | Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and methods of use thereof |
| CN112957332B (zh) * | 2021-02-04 | 2023-04-25 | 海南通用康力制药有限公司 | 注射用磷酸特地唑胺及其质量标准 |
| CN112957333B (zh) * | 2021-02-05 | 2022-11-22 | 海南通用康力制药有限公司 | 注射用磷酸特地唑胺及其制备方法 |
| CN113197874B (zh) * | 2021-04-28 | 2023-05-26 | 北京福元医药股份有限公司 | 一种磷酸特地唑胺口服固体制剂 |
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| LU80081A1 (fr) | 1977-08-26 | 1979-05-15 | Delalande Sa | Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique |
| US4128654A (en) | 1978-02-10 | 1978-12-05 | E. I. Du Pont De Nemours And Company | 5-Halomethyl-3-phenyl-2-oxazolidinones |
| US4340606A (en) | 1980-10-23 | 1982-07-20 | E. I. Du Pont De Nemours And Company | 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents |
| FR2500450A1 (fr) | 1981-02-25 | 1982-08-27 | Delalande Sa | Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique |
| US4461773A (en) | 1982-09-15 | 1984-07-24 | E. I. Dupont De Nemours And Company | P-Oxooxazolidinylbenzene compounds as antibacterial agents |
| CA1320730C (en) | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
| US5254577A (en) | 1988-07-29 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US4948801A (en) | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US5144911A (en) * | 1990-11-28 | 1992-09-08 | Moore Cheri L | Component bed system for a pet |
| EP0610265B1 (en) | 1991-11-01 | 1996-12-27 | PHARMACIA & UPJOHN COMPANY | Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents |
| SK283420B6 (sk) | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| WO1994013649A1 (en) | 1992-12-08 | 1994-06-23 | The Upjohn Company | Tropone-substituted phenyloxazolidinone antibacterial agents |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
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| CA2174107C (en) | 1993-11-22 | 2005-04-12 | Steven J. Brickner | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
| GB9702213D0 (en) | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
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| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
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| YU52403A (sh) | 2000-12-26 | 2006-03-03 | Dr.Reddy's Research Foundation | Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže |
| DE60212959T2 (de) | 2001-04-07 | 2007-02-15 | Astrazeneca Ab | Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika |
| US6623140B2 (en) | 2001-04-13 | 2003-09-23 | Scott R. Watterson | Illumination device having multiple light sources |
| US6627646B2 (en) * | 2001-07-17 | 2003-09-30 | Sepracor Inc. | Norastemizole polymorphs |
| SI1427711T1 (sl) | 2001-09-11 | 2005-12-31 | Astrazeneca Ab | Oksazolidinonski in/ali izoksazolinski derivati kot antibakterijska sredstva |
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| NZ515881A (en) | 2001-12-03 | 2004-09-24 | New Zealand Dairy Board | Cheese flavour ingredient and method of its production |
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| CN1653064A (zh) | 2002-02-28 | 2005-08-10 | 阿斯特拉曾尼卡有限公司 | 噁唑烷酮衍生物、其制备方法以及包含它们的药用组合物 |
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| US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| TW200500360A (en) | 2003-03-01 | 2005-01-01 | Astrazeneca Ab | Hydroxymethyl compounds |
| GB0306358D0 (en) | 2003-03-20 | 2003-04-23 | Astrazeneca Ab | Chemical compounds |
| US20070185132A1 (en) | 2003-07-02 | 2007-08-09 | Yasumichi Fukuda | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereo |
| ATE471937T1 (de) | 2003-07-02 | 2010-07-15 | Merck Sharp & Dohme | Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon |
| NZ529860A (en) | 2003-11-28 | 2006-10-27 | Ovita Ltd | Muscle growth regulator mighty and use in promoting muscle mass and treating muscle wasting diseases |
| WO2005051933A1 (en) | 2003-11-28 | 2005-06-09 | Ranbaxy Laboratories Limited | An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby |
| AR046782A1 (es) | 2003-12-17 | 2005-12-21 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos. |
| KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| US20070191336A1 (en) | 2003-12-24 | 2007-08-16 | Flynn Daniel L | Anti-inflammatory medicaments |
| US20080064689A1 (en) | 2004-05-25 | 2008-03-13 | Astrazeneca Ab | 3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents |
| WO2005116024A1 (en) | 2004-05-25 | 2005-12-08 | Astrazeneca Ab | 3- (4- (2-dihydroisoxazol-3-ylpyridin-5-yl) phenyl) -5-triazol-1-ylmethyloxazolidin-2-one derivaives as mao inhibitors for the treatment of bacterial infections |
| GB0411596D0 (en) | 2004-05-25 | 2004-06-30 | Astrazeneca Ab | Chemical process |
| CA2567929A1 (en) | 2004-05-25 | 2005-12-08 | Astrazeneca Ab | 3- {4- (pyridin-3-yl) phenyl} -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents |
| JP2008500317A (ja) | 2004-05-25 | 2008-01-10 | アストラゼネカ アクチボラグ | 抗菌剤としての３−’４−｛６−置換アルカノイル）ピリジン−３−イル｝−３−フェニル−５−（１ｈ−１，２，３−トリアゾール−１−イルメチル）−１，３−オキサゾリジン−２−オン |
| WO2006038100A1 (en) | 2004-10-08 | 2006-04-13 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
| WO2007023507A2 (en) | 2005-06-20 | 2007-03-01 | Wockhardt Limited | Oxazolidinones bearing antimicrobial activity composition and methods of preparation |
| WO2007138381A2 (en) | 2005-10-14 | 2007-12-06 | Targanta Therapeutics Inc. | Phosphonated oxazolidinones and uses thereof for the prevention and treatment of bone and joint infections |
| JP5455906B2 (ja) * | 2007-08-06 | 2014-03-26 | ミクウルク ファーマシューティカルズ，インコーポレイテッド | 細菌感染症治療のための抗微生物性オルト−フルオロフェニルオキサゾリジノン |
| CN101220001A (zh) * | 2008-01-25 | 2008-07-16 | 浙江博泰化工有限公司 | 一种利奈唑酮的合成方法 |
| RU2659792C1 (ru) | 2008-10-10 | 2018-07-04 | Мерк Шарп Энд Домэ Корп. | Оксазолидиноны и способ их очистки |
| MY156354A (en) | 2009-02-03 | 2016-02-15 | Merck Sharp & Dohme | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
| US8580767B2 (en) | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
-
2010
- 2010-02-03 MY MYPI2011003576A patent/MY156354A/en unknown
- 2010-02-03 AU AU2010210627A patent/AU2010210627B2/en active Active
- 2010-02-03 MX MX2011008093A patent/MX2011008093A/es not_active Application Discontinuation
- 2010-02-03 CN CN201710063034.9A patent/CN107082790A/zh active Pending
- 2010-02-03 EP EP10703403.5A patent/EP2393808B1/en active Active
- 2010-02-03 PE PE2011001433A patent/PE20120585A1/es active IP Right Grant
- 2010-02-03 MX MX2015007856A patent/MX384300B/es unknown
- 2010-02-03 MA MA34136A patent/MA33092B1/fr unknown
- 2010-02-03 RU RU2016100418A patent/RU2655928C1/ru active
- 2010-02-03 CA CA2751392A patent/CA2751392C/en active Active
- 2010-02-03 SG SG2011055456A patent/SG173497A1/en unknown
- 2010-02-03 CU CU2011000155A patent/CU24089B1/es active IP Right Grant
- 2010-02-03 AP AP2011005835A patent/AP2987A/xx active
- 2010-02-03 NZ NZ620458A patent/NZ620458A/en unknown
- 2010-02-03 KR KR1020177034181A patent/KR101918678B1/ko active Active
- 2010-02-03 ES ES10703403T patent/ES2734724T3/es active Active
- 2010-02-03 SG SG10201500207QA patent/SG10201500207QA/en unknown
- 2010-02-03 RU RU2011136537/04A patent/RU2011136537A/ru not_active Application Discontinuation
- 2010-02-03 KR KR1020117020614A patent/KR101739923B1/ko active Active
- 2010-02-03 JP JP2011549242A patent/JP5584705B2/ja active Active
- 2010-02-03 NZ NZ594408A patent/NZ594408A/en active IP Right Revival
- 2010-02-03 KR KR1020177008992A patent/KR20170040371A/ko not_active Ceased
- 2010-02-03 WO PCT/US2010/023122 patent/WO2010091131A1/en not_active Ceased
- 2010-02-03 NZ NZ712289A patent/NZ712289A/en unknown
- 2010-02-03 UA UAA201110617A patent/UA114068C2/uk unknown
- 2010-02-03 US US12/699,864 patent/US8426389B2/en active Active
- 2010-02-03 CN CN2010800143630A patent/CN102439006A/zh active Pending
- 2010-02-03 BR BRPI1008829A patent/BRPI1008829A2/pt not_active Application Discontinuation
-
2011
- 2011-08-01 MX MX2020011773A patent/MX2020011773A/es unknown
- 2011-08-01 DO DO2011000251A patent/DOP2011000251A/es unknown
- 2011-08-02 IL IL214401A patent/IL214401B/en active IP Right Grant
- 2011-08-02 CO CO11097215A patent/CO6620071A2/es not_active Application Discontinuation
- 2011-08-02 CL CL2011001855A patent/CL2011001855A1/es unknown
- 2011-08-03 TN TN2011000381A patent/TN2011000381A1/fr unknown
- 2011-08-23 EC EC2011011285A patent/ECSP11011285A/es unknown
- 2011-08-30 CR CR20110464A patent/CR20110464A/es unknown
- 2011-09-01 ZA ZA2011/06412A patent/ZA201106412B/en unknown
-
2013
- 2013-04-22 US US13/867,951 patent/US20130310343A1/en not_active Abandoned
- 2013-08-30 ZA ZA2013/06536A patent/ZA201306536B/en unknown
-
2014
- 2014-01-10 PH PH12014500092A patent/PH12014500092B1/en unknown
-
2015
- 2015-12-04 US US14/959,412 patent/US9624250B2/en active Active
-
2017
- 2017-03-10 US US15/455,463 patent/US9988406B2/en active Active
-
2018
- 2018-05-03 US US15/970,492 patent/US10065947B1/en active Active
- 2018-05-03 US US15/970,486 patent/US10442829B2/en active Active
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